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The map label for this gene is ppx [H]

Identifier: 94311115

GI number: 94311115

Start: 2382819

End: 2384351

Strand: Reverse

Name: ppx [H]

Synonym: Rmet_2177

Alternate gene names: 94311115

Gene position: 2384351-2382819 (Counterclockwise)

Preceding gene: 94311117

Following gene: 335055584

Centisome position: 60.7

GC content: 63.93

Gene sequence:

>1533_bases
ATGACACAGACTCCCCGCTTGCTGGCCGCCGTCGACATGGGCTCCAACAGCTTCCGCCTGATGATTGGGCGGGTGGATGA
AACCCCCACGGCTTCCGGCCCCGCCAGCCAGATCTTCCAGGTCGACGCACTCCGTGAGCCGGTTCGCCTGGCCGCCGGCC
TGACCCCCGACAAGTATCTGGATCAGCCGGCCCGCCGCCGCGGTATCGAGGCCCTGCGACGCTTCGGTGACCGCCTGCGT
GACTTCTCTCCCGACCAGGTACGCGCCGTGGCGACGAATACGCTGCGCGTGGCCAAGAATGCCTCTGAATTCCTGATCGA
GGCCGAGGCGGCGCTTGGGTTCCCCATCGAAGTCATTGCCGGCCGGGAAGAGGCGCGACTGATCTACCTGGGCGCCTCGC
ACGACGCACCCGCCTGCCAGGGCAACCGGCTCGTCGTCGATATCGGCGGCGGCTCCACCGAGTTCATCATCGGTAGCGGC
TACCAGTCGAAGTTGATGGAAAGTCTCTACATCGGTTGCGTGTCTCACAGCCGCCAGTTCTTTCCAAGCGGCAACGTCGA
TGAATACGCAATGAAGCAGGCCGAGCTTGCCGCGCGTCGCGAGATCCAGGTGCTGGTCCGCCAGTATCGGGCCGCAGGCT
GGCAGCAGGCGGTGGGCTCGTCAGGCACGGCGCGGGCGTTGGCCGAGCTGATCGAGCTGAACGGCATGAACGACAGTGCG
TCCGAGCATGGCATCACGCGTGAAGGTCTGGAGCGGCTAAAGCGCGCGCTGGTTAAGGCCGAGAACGCCAACCGCGTGAA
GCTCGCCGGCCTCAAGGCAGACCGTATTCCCGTGCTACCTGGCGGATTGTCGATCATGCTTGGCGTGTTCGCGGAGCTCG
ATCTCGACCGCATGGACGTGACCGATGGCGCGTTGCGGCTCGGTGTGTTGTACGACCTGCTCGGCCGCAGTCATCACGAG
GATATGCGCACGGTCACCGTGGATCAGTTCATGCGCCGCTACGGTGTCGATCGCGCGCAAGCGGGCCGGGTAGGGGTGGC
CGCACGAGACCTGCTTTCGCAGTTTCCCGATCCGCCCAACGAACGCCGCTCCGATAACCTGGCACTGCTGGGCTGGGCTG
CAAGCCTGCACGAGATCGGCATGACGATCTCGCACAGCGGCTATCACAAGCACTCGGCCTACATCGCGACGCATGCTGAC
ATGCCGGGGTTCTCGAAGACCGATCAGGCGCGTCTTGCCACGCTGCTGCTCGGACACGCGAGCAAGCTCAGCAAGCTCTC
GGGCAGCGGAAAGTTTCTCGACTGGCGCATGCTGTTCAGCCTTCGACTCGCTTTCGTGTTGTGCCGTCGGCGTGCCGATG
TGAAGCTGCCCGAGATTCAGGTTGGCCAGCGCTCCGACGAACTCGACGAAGGGTTTGAAGTACGATTGCCGAAGTCGTGG
ATCGACATGAATCCGCTCGTCGAATACAGCCTGGCGCAGGAGGCGGATGAGTGGGAGCGCATCGGCAAGCGGTACAAGGT
GGTCTACGTCTAA

Upstream 100 bases:

>100_bases
CAGTTTAATGACACTTTGATTTTGTCATGATGCGGACATGGCTACGACATAATCTTACGAGTTTGGCTCACCAGAGCCTA
GCTCGCGCTTGACAGACGCA

Downstream 100 bases:

>100_bases
GGTGCGTCTGACTGGGAGCCATCTCGGGCCTCAGATTGACGTGGCCTGCGATGCAAAACGGCGACTCCAGGGAGTCGCCG
TTTTGTTTGCCAGGTCAGAG

Product: exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTQTPRLLAAVDMGSNSFRLMIGRVDETPTASGPASQIFQVDALREPVRLAAGLTPDKYLDQPARRRGIEALRRFGDRLR
DFSPDQVRAVATNTLRVAKNASEFLIEAEAALGFPIEVIAGREEARLIYLGASHDAPACQGNRLVVDIGGGSTEFIIGSG
YQSKLMESLYIGCVSHSRQFFPSGNVDEYAMKQAELAARREIQVLVRQYRAAGWQQAVGSSGTARALAELIELNGMNDSA
SEHGITREGLERLKRALVKAENANRVKLAGLKADRIPVLPGGLSIMLGVFAELDLDRMDVTDGALRLGVLYDLLGRSHHE
DMRTVTVDQFMRRYGVDRAQAGRVGVAARDLLSQFPDPPNERRSDNLALLGWAASLHEIGMTISHSGYHKHSAYIATHAD
MPGFSKTDQARLATLLLGHASKLSKLSGSGKFLDWRMLFSLRLAFVLCRRRADVKLPEIQVGQRSDELDEGFEVRLPKSW
IDMNPLVEYSLAQEADEWERIGKRYKVVYV

Sequences:

>Translated_510_residues
MTQTPRLLAAVDMGSNSFRLMIGRVDETPTASGPASQIFQVDALREPVRLAAGLTPDKYLDQPARRRGIEALRRFGDRLR
DFSPDQVRAVATNTLRVAKNASEFLIEAEAALGFPIEVIAGREEARLIYLGASHDAPACQGNRLVVDIGGGSTEFIIGSG
YQSKLMESLYIGCVSHSRQFFPSGNVDEYAMKQAELAARREIQVLVRQYRAAGWQQAVGSSGTARALAELIELNGMNDSA
SEHGITREGLERLKRALVKAENANRVKLAGLKADRIPVLPGGLSIMLGVFAELDLDRMDVTDGALRLGVLYDLLGRSHHE
DMRTVTVDQFMRRYGVDRAQAGRVGVAARDLLSQFPDPPNERRSDNLALLGWAASLHEIGMTISHSGYHKHSAYIATHAD
MPGFSKTDQARLATLLLGHASKLSKLSGSGKFLDWRMLFSLRLAFVLCRRRADVKLPEIQVGQRSDELDEGFEVRLPKSW
IDMNPLVEYSLAQEADEWERIGKRYKVVYV
>Mature_509_residues
TQTPRLLAAVDMGSNSFRLMIGRVDETPTASGPASQIFQVDALREPVRLAAGLTPDKYLDQPARRRGIEALRRFGDRLRD
FSPDQVRAVATNTLRVAKNASEFLIEAEAALGFPIEVIAGREEARLIYLGASHDAPACQGNRLVVDIGGGSTEFIIGSGY
QSKLMESLYIGCVSHSRQFFPSGNVDEYAMKQAELAARREIQVLVRQYRAAGWQQAVGSSGTARALAELIELNGMNDSAS
EHGITREGLERLKRALVKAENANRVKLAGLKADRIPVLPGGLSIMLGVFAELDLDRMDVTDGALRLGVLYDLLGRSHHED
MRTVTVDQFMRRYGVDRAQAGRVGVAARDLLSQFPDPPNERRSDNLALLGWAASLHEIGMTISHSGYHKHSAYIATHADM
PGFSKTDQARLATLLLGHASKLSKLSGSGKFLDWRMLFSLRLAFVLCRRRADVKLPEIQVGQRSDELDEGFEVRLPKSWI
DMNPLVEYSLAQEADEWERIGKRYKVVYV

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=511, Percent_Identity=38.5518590998043, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI48994966, Length=506, Percent_Identity=35.9683794466403, Blast_Score=295, Evalue=4e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 56388; Mature: 56257

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTPRLLAAVDMGSNSFRLMIGRVDETPTASGPASQIFQVDALREPVRLAAGLTPDKYL
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHEEHHHHHHHHHHHCCCCCHHHH
DQPARRRGIEALRRFGDRLRDFSPDQVRAVATNTLRVAKNASEFLIEAEAALGFPIEVIA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHEEHHHHCCCCEEEEC
GREEARLIYLGASHDAPACQGNRLVVDIGGGSTEFIIGSGYQSKLMESLYIGCVSHSRQF
CCCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
FPSGNVDEYAMKQAELAARREIQVLVRQYRAAGWQQAVGSSGTARALAELIELNGMNDSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCH
SEHGITREGLERLKRALVKAENANRVKLAGLKADRIPVLPGGLSIMLGVFAELDLDRMDV
HHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
TDGALRLGVLYDLLGRSHHEDMRTVTVDQFMRRYGVDRAQAGRVGVAARDLLSQFPDPPN
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCCCCCC
ERRSDNLALLGWAASLHEIGMTISHSGYHKHSAYIATHADMPGFSKTDQARLATLLLGHA
CCCCCCEEEEEHHHHHHHHCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
SKLSKLSGSGKFLDWRMLFSLRLAFVLCRRRADVKLPEIQVGQRSDELDEGFEVRLPKSW
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEEECCHHH
IDMNPLVEYSLAQEADEWERIGKRYKVVYV
CCCCHHHHHHHHHCHHHHHHHCCEEEEEEC
>Mature Secondary Structure 
TQTPRLLAAVDMGSNSFRLMIGRVDETPTASGPASQIFQVDALREPVRLAAGLTPDKYL
CCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHEEHHHHHHHHHHHCCCCCHHHH
DQPARRRGIEALRRFGDRLRDFSPDQVRAVATNTLRVAKNASEFLIEAEAALGFPIEVIA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHEEHHHHCCCCEEEEC
GREEARLIYLGASHDAPACQGNRLVVDIGGGSTEFIIGSGYQSKLMESLYIGCVSHSRQF
CCCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
FPSGNVDEYAMKQAELAARREIQVLVRQYRAAGWQQAVGSSGTARALAELIELNGMNDSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCH
SEHGITREGLERLKRALVKAENANRVKLAGLKADRIPVLPGGLSIMLGVFAELDLDRMDV
HHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
TDGALRLGVLYDLLGRSHHEDMRTVTVDQFMRRYGVDRAQAGRVGVAARDLLSQFPDPPN
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCCCCCC
ERRSDNLALLGWAASLHEIGMTISHSGYHKHSAYIATHADMPGFSKTDQARLATLLLGHA
CCCCCCEEEEEHHHHHHHHCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
SKLSKLSGSGKFLDWRMLFSLRLAFVLCRRRADVKLPEIQVGQRSDELDEGFEVRLPKSW
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEEECCHHH
IDMNPLVEYSLAQEADEWERIGKRYKVVYV
CCCCHHHHHHHHHCHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]