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The map label for this gene is rcsB [H]

Identifier: 94311091

GI number: 94311091

Start: 2350869

End: 2351510

Strand: Direct

Name: rcsB [H]

Synonym: Rmet_2153

Alternate gene names: 94311091

Gene position: 2350869-2351510 (Clockwise)

Preceding gene: 94311090

Following gene: 94311092

Centisome position: 59.85

GC content: 60.28

Gene sequence:

>642_bases
ATGCCCATTTCGATCATGGTCCTGGATGACCACGAAATTGTTCATCAGGGTATCGTCCGGGTACTGCAGCAGAACTCTGC
ATTCGCAATTCTCGGGACATTCACCCGCAGCAGGGATTTCGTGCAGGCGCTCAGGAACAAGGCGCCCGATCTGGTGATCA
TCGACTATGCGCTAGAGCCTTCGGATGCGGACGGCATCGGCGTTATCCGGATGATCCGGCGACAGTATCCGGGCATCAAG
ATCCTCGTTCTATCCGCCCACGACAGCCCCGTCACTATCGCCCTGGCAATGAAGGCGGGGGCCGATGGGTACTGCATCAA
GAACGGCTCGATTGCCGATATTACGGCGGCTATCGCCAAGATTCTCCGGGGGGCAAGCCACATCCCAGCCCAGGTTGCCT
CGCTTTCCGTGTTCGGCAAGGAACAGGGGGAAGGCGCGCCGGGCTCGGGGGGCCTCACCGCCGCGCTGACCGAAAAGGAA
CGCGAGGTGCTCAGGTGCTTTCTGGACGGGATGACGGTCAACGAAATCGCCGCGAAATTCTCGCGCAGCAAGAAGACGGT
GAGCGGCCACAAGCAGTCGGCGCTCCGCAAGCTGGGGATCCGCTCCGACAACGAACTGTTCAAGGTGCGCCACCTTATCT
GA

Upstream 100 bases:

>100_bases
GGAGTGGTTCCGGCAAGACGCCGATAACGTGTGACGCCTCGGGCGCGATTGCTGCAAGGCTTATAATTCAGCGCCTGCGA
TACGTCTTGGAAACCGCAAA

Downstream 100 bases:

>100_bases
CCTACGCCCAGCGACTTGCCCGCAACCCAGGACGAAGATATCGATGTCGGCACCGAATCCCCACGCATCATGAAACGGGC
ACTGCTTCTGATCCTGGCTG

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MPISIMVLDDHEIVHQGIVRVLQQNSAFAILGTFTRSRDFVQALRNKAPDLVIIDYALEPSDADGIGVIRMIRRQYPGIK
ILVLSAHDSPVTIALAMKAGADGYCIKNGSIADITAAIAKILRGASHIPAQVASLSVFGKEQGEGAPGSGGLTAALTEKE
REVLRCFLDGMTVNEIAAKFSRSKKTVSGHKQSALRKLGIRSDNELFKVRHLI

Sequences:

>Translated_213_residues
MPISIMVLDDHEIVHQGIVRVLQQNSAFAILGTFTRSRDFVQALRNKAPDLVIIDYALEPSDADGIGVIRMIRRQYPGIK
ILVLSAHDSPVTIALAMKAGADGYCIKNGSIADITAAIAKILRGASHIPAQVASLSVFGKEQGEGAPGSGGLTAALTEKE
REVLRCFLDGMTVNEIAAKFSRSKKTVSGHKQSALRKLGIRSDNELFKVRHLI
>Mature_212_residues
PISIMVLDDHEIVHQGIVRVLQQNSAFAILGTFTRSRDFVQALRNKAPDLVIIDYALEPSDADGIGVIRMIRRQYPGIKI
LVLSAHDSPVTIALAMKAGADGYCIKNGSIADITAAIAKILRGASHIPAQVASLSVFGKEQGEGAPGSGGLTAALTEKER
EVLRCFLDGMTVNEIAAKFSRSKKTVSGHKQSALRKLGIRSDNELFKVRHLI

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=32.512315270936, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788222, Length=214, Percent_Identity=29.9065420560748, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=30.7317073170732, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=27.6699029126214, Blast_Score=88, Evalue=3e-19,
Organism=Escherichia coli, GI1788712, Length=209, Percent_Identity=32.0574162679426, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788521, Length=205, Percent_Identity=24.8780487804878, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22956; Mature: 22825

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISIMVLDDHEIVHQGIVRVLQQNSAFAILGTFTRSRDFVQALRNKAPDLVIIDYALEP
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHCCCCCEEEEEEEECC
SDADGIGVIRMIRRQYPGIKILVLSAHDSPVTIALAMKAGADGYCIKNGSIADITAAIAK
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCCEEEECCCHHHHHHHHHH
ILRGASHIPAQVASLSVFGKEQGEGAPGSGGLTAALTEKEREVLRCFLDGMTVNEIAAKF
HHCCCCCCCHHHHHHHEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHH
SRSKKTVSGHKQSALRKLGIRSDNELFKVRHLI
HHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure 
PISIMVLDDHEIVHQGIVRVLQQNSAFAILGTFTRSRDFVQALRNKAPDLVIIDYALEP
CEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHCCCCCEEEEEEEECC
SDADGIGVIRMIRRQYPGIKILVLSAHDSPVTIALAMKAGADGYCIKNGSIADITAAIAK
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCCEEEECCCHHHHHHHHHH
ILRGASHIPAQVASLSVFGKEQGEGAPGSGGLTAALTEKEREVLRCFLDGMTVNEIAAKF
HHCCCCCCCHHHHHHHEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHH
SRSKKTVSGHKQSALRKLGIRSDNELFKVRHLI
HHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]