Click here to switch to the map view.

The map label for this gene is der [H]

Identifier: 94311040

GI number: 94311040

Start: 2282796

End: 2284139

Strand: Reverse

Name: der [H]

Synonym: Rmet_2102

Alternate gene names: 94311040

Gene position: 2284139-2282796 (Counterclockwise)

Preceding gene: 94311041

Following gene: 94311039

Centisome position: 58.15

GC content: 63.1

Gene sequence:

>1344_bases
ATGAAACCAGTTATCGCACTCGTCGGCCGTCCCAATGTAGGGAAGTCGACGCTATTCAATCGCATGACCCGCTCGCGCGA
CGCGCTCGTCGCCGATTTGCCGGGCCTGACACGGGACCGCCATTACGGCGAGGGCCGTATCGGCGATCGCCCCTTCATCG
TGATCGATACCGGGGGCTTCGAGCCGGTGGCCAAGGAAGGCATCGTGGCCGAAATGGCCAAGCAGACGCGCCAGGCCGTG
GTGGAAGCGGATGTCGTCATCTTTCTCGTCGATGGTCGCCTGGGGCTGGCGCCGCAGGACCGTGTCATCGCGGACTACCT
CCGCAAGACAGGTCGCCGCGTGATGCTGGCGATCAACAAGGCCGAGGGCATGAAGTACACCTCGGTGGCCGCGGATTTCT
ATGAACTGGGCATGGGTGATCCGTACGCGATCTCGTCGACGCATGGCGACGGCGTGCGCGAACTGGTCGATGAAGCCCTC
GACCTGGCCGTTCAGGAGCGTCCGGAACTGGCAGATCAGGAAGATGCCGGCCAGCACGGCGTCAAGATCGCCATCGTTGG
TCGCCCGAACGTCGGCAAGTCCACGCTCGTGAACACCCTGATCGGCGAAGAGCGCGTGATTGCCTTCGACATGCCGGGTA
CCACGCGCGACGCTATCTATGTGGAGTTCGAGCGTGGCGGCAAGCCTTACACGCTGATTGACACGGCTGGCCTGCGCAAG
CGCGGCAAGGTGTTCGAAGCGATTGAGAAGTTCTCGGTGGTCAAGACGCTGCAGTCGATCGCGGACGCCAATGTGGTGGT
GCTGCTGCTCGATGCCCAGCAGGATATCTCCGAGCAGGACGCGCATATCGCCGGGTTCATCGTGGAGTCGGGCAGGGCGT
TGGTGGTAGGCGTGAACAAGTGGGACGGCCTGGACGGCCATCAGCGCGACCGGGTCAAGCACGACCTGGAGCGCAAGTTG
CAGTTCCTGAGTTTCGCGAACATCCACTTCGTATCCGCCCGCGAGCGCACCGGCATTGGCGCGCTTTTGCGCTCGGTGGA
CGACGCGTACGCCGCTGCGATGATCAAGCTTCCGACGCCGCAGATCACGCGGGTGCTCCAGGAAGCGGTGGAGTTCCAGC
AGCCGAAGCGCGTGGGCGTGTCCCGCCCGAAACTGCGCTACGCGCACCAGGGTGGATCGAATCCGCCGATCATCGTTGTG
CACGGGAACGCGCTGTCCGGCGTGACCGACGCGTACCGGCGCTACCTCGAGAACCGCTTCCGCACGGCGTTCAAACTCAA
GGGAACACCGCTTCGGATCGAATTTCGTACGAACAAAAACCCGTACGCCGAATCGAAGGATTGA

Upstream 100 bases:

>100_bases
AAAAGCGGCCAGACGTGCATAGGCACGATGGTTGTCGGATCAACATGACTCCGGAATAGCTGGGGGACGGCGCGAGCCGC
CCCCTGTTTCCGTTTATTGA

Downstream 100 bases:

>100_bases
CCAGGAAAAGGGACAGGTTTTGCCGCCAAGTTTCGTTTGCGTTCGTTTGGAACTGCGGCTAAATTCACGGTAGCGGGGAA
ACCCTGCTCGTAGATGCCAG

Product: GTP-binding protein Der

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKPVIALVGRPNVGKSTLFNRMTRSRDALVADLPGLTRDRHYGEGRIGDRPFIVIDTGGFEPVAKEGIVAEMAKQTRQAV
VEADVVIFLVDGRLGLAPQDRVIADYLRKTGRRVMLAINKAEGMKYTSVAADFYELGMGDPYAISSTHGDGVRELVDEAL
DLAVQERPELADQEDAGQHGVKIAIVGRPNVGKSTLVNTLIGEERVIAFDMPGTTRDAIYVEFERGGKPYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISEQDAHIAGFIVESGRALVVGVNKWDGLDGHQRDRVKHDLERKL
QFLSFANIHFVSARERTGIGALLRSVDDAYAAAMIKLPTPQITRVLQEAVEFQQPKRVGVSRPKLRYAHQGGSNPPIIVV
HGNALSGVTDAYRRYLENRFRTAFKLKGTPLRIEFRTNKNPYAESKD

Sequences:

>Translated_447_residues
MKPVIALVGRPNVGKSTLFNRMTRSRDALVADLPGLTRDRHYGEGRIGDRPFIVIDTGGFEPVAKEGIVAEMAKQTRQAV
VEADVVIFLVDGRLGLAPQDRVIADYLRKTGRRVMLAINKAEGMKYTSVAADFYELGMGDPYAISSTHGDGVRELVDEAL
DLAVQERPELADQEDAGQHGVKIAIVGRPNVGKSTLVNTLIGEERVIAFDMPGTTRDAIYVEFERGGKPYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISEQDAHIAGFIVESGRALVVGVNKWDGLDGHQRDRVKHDLERKL
QFLSFANIHFVSARERTGIGALLRSVDDAYAAAMIKLPTPQITRVLQEAVEFQQPKRVGVSRPKLRYAHQGGSNPPIIVV
HGNALSGVTDAYRRYLENRFRTAFKLKGTPLRIEFRTNKNPYAESKD
>Mature_447_residues
MKPVIALVGRPNVGKSTLFNRMTRSRDALVADLPGLTRDRHYGEGRIGDRPFIVIDTGGFEPVAKEGIVAEMAKQTRQAV
VEADVVIFLVDGRLGLAPQDRVIADYLRKTGRRVMLAINKAEGMKYTSVAADFYELGMGDPYAISSTHGDGVRELVDEAL
DLAVQERPELADQEDAGQHGVKIAIVGRPNVGKSTLVNTLIGEERVIAFDMPGTTRDAIYVEFERGGKPYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISEQDAHIAGFIVESGRALVVGVNKWDGLDGHQRDRVKHDLERKL
QFLSFANIHFVSARERTGIGALLRSVDDAYAAAMIKLPTPQITRVLQEAVEFQQPKRVGVSRPKLRYAHQGGSNPPIIVV
HGNALSGVTDAYRRYLENRFRTAFKLKGTPLRIEFRTNKNPYAESKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=470, Percent_Identity=50.2127659574468, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=39.3617021276596, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788919, Length=121, Percent_Identity=33.8842975206612, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=235, Percent_Identity=28.0851063829787, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550813, Length=161, Percent_Identity=32.2981366459627, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49324; Mature: 49324

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRMTRSRDALVADLPGLTRDRHYGEGRIGDRPFIVIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKEGIVAEMAKQTRQAVVEADVVIFLVDGRLGLAPQDRVIADYLRKTGRRVMLAINK
CHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEC
AEGMKYTSVAADFYELGMGDPYAISSTHGDGVRELVDEALDLAVQERPELADQEDAGQHG
CCCCEEHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VKIAIVGRPNVGKSTLVNTLIGEERVIAFDMPGTTRDAIYVEFERGGKPYTLIDTAGLRK
EEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCH
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISEQDAHIAGFIVESGRALVVGVNK
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCC
WDGLDGHQRDRVKHDLERKLQFLSFANIHFVSARERTGIGALLRSVDDAYAAAMIKLPTP
CCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCH
QITRVLQEAVEFQQPKRVGVSRPKLRYAHQGGSNPPIIVVHGNALSGVTDAYRRYLENRF
HHHHHHHHHHHHCCCHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
RTAFKLKGTPLRIEFRTNKNPYAESKD
HEEEEECCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRMTRSRDALVADLPGLTRDRHYGEGRIGDRPFIVIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKEGIVAEMAKQTRQAVVEADVVIFLVDGRLGLAPQDRVIADYLRKTGRRVMLAINK
CHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEC
AEGMKYTSVAADFYELGMGDPYAISSTHGDGVRELVDEALDLAVQERPELADQEDAGQHG
CCCCEEHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VKIAIVGRPNVGKSTLVNTLIGEERVIAFDMPGTTRDAIYVEFERGGKPYTLIDTAGLRK
EEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCH
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISEQDAHIAGFIVESGRALVVGVNK
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCC
WDGLDGHQRDRVKHDLERKLQFLSFANIHFVSARERTGIGALLRSVDDAYAAAMIKLPTP
CCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCH
QITRVLQEAVEFQQPKRVGVSRPKLRYAHQGGSNPPIIVVHGNALSGVTDAYRRYLENRF
HHHHHHHHHHHHCCCHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
RTAFKLKGTPLRIEFRTNKNPYAESKD
HEEEEECCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA