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The map label for this gene is cynT [H]

Identifier: 94311016

GI number: 94311016

Start: 2257111

End: 2257845

Strand: Direct

Name: cynT [H]

Synonym: Rmet_2078

Alternate gene names: 94311016

Gene position: 2257111-2257845 (Clockwise)

Preceding gene: 94311015

Following gene: 94311017

Centisome position: 57.46

GC content: 65.99

Gene sequence:

>735_bases
ATGCACGAGATCGAACGTCTGCTCAAGGGCTTCGAACGGTTCCAGCGGCGCTACTTCGAGGCCAGGCCGGAACTCTTCGA
TGCCCTGCGCACGGGCCAGAAGCCTCAGACGCTGCTGATCGGCTGTAGCGATTCGCGCGTGGACCCGGGCCTGCTGCTCG
ACTGCGACCCGGGAGAGCTGTTCACGGTGCGCAACGTCGCCAACCTCGTACCGCCGTGCGGGGATGGCGCCAGCGGGCGG
CTCCACGGTGTCTCGGCGGCGATCCAGTTCGCCGTGGAGCAACTGCATGTGGTCCGCATCATCGTGATGGGCCACGCTGG
ATGTGGCGGCATCCGTGCTTTGCTGGCCCATCCGCAAAACGACGATACGAACGCGCCGCAGGACTTTATCGGGCCCTGGG
TCCGCATTGCAGGCCCTGCCCGGCGCATGGTCGAGCAGACGCTGCCCAACGCCAGTCCCGCGGAACGGCAGCGCGCATGC
GAACAAGCGGCGATCCTGGTGTCGCTGCGCAATCTCGAGAGTTTTCCGTTCGTCCGCGAGGCCTGCGAGCGCGGTGCGCT
CACGCTGCATGGCTGGTACTTCGACCTCCAGGCGGGCGCGCTGCTGGCCTACTCGGAACGTGCAGACGACTTCCTGCCGC
TGGTCTGCCCTCTGACACCTGAGGCGCGCCCGCATCGTCAACCGTCGAATCGCCCCAGCATTGACAGCGGTCAAGCCGAA
ATGCTGGGTTCTTAA

Upstream 100 bases:

>100_bases
CCCGTTCACGCGACTGGTGCACGTCTGGAGCGGCTTTGCCTCGGTGACCTACCTGGGACGCGCCTGGCAACTCGTCCGGG
GCCGGTAAGGCCGTGTCCCC

Downstream 100 bases:

>100_bases
TAATGATGTCGGCATTTGCCCCACTCGCTGGCGAACCCATGCCAACCCTGCGCTGGATCTGCATTCCCATCCTTTCGTGT
ATTGCCGCCACGGCTATCGC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MHEIERLLKGFERFQRRYFEARPELFDALRTGQKPQTLLIGCSDSRVDPGLLLDCDPGELFTVRNVANLVPPCGDGASGR
LHGVSAAIQFAVEQLHVVRIIVMGHAGCGGIRALLAHPQNDDTNAPQDFIGPWVRIAGPARRMVEQTLPNASPAERQRAC
EQAAILVSLRNLESFPFVREACERGALTLHGWYFDLQAGALLAYSERADDFLPLVCPLTPEARPHRQPSNRPSIDSGQAE
MLGS

Sequences:

>Translated_244_residues
MHEIERLLKGFERFQRRYFEARPELFDALRTGQKPQTLLIGCSDSRVDPGLLLDCDPGELFTVRNVANLVPPCGDGASGR
LHGVSAAIQFAVEQLHVVRIIVMGHAGCGGIRALLAHPQNDDTNAPQDFIGPWVRIAGPARRMVEQTLPNASPAERQRAC
EQAAILVSLRNLESFPFVREACERGALTLHGWYFDLQAGALLAYSERADDFLPLVCPLTPEARPHRQPSNRPSIDSGQAE
MLGS
>Mature_244_residues
MHEIERLLKGFERFQRRYFEARPELFDALRTGQKPQTLLIGCSDSRVDPGLLLDCDPGELFTVRNVANLVPPCGDGASGR
LHGVSAAIQFAVEQLHVVRIIVMGHAGCGGIRALLAHPQNDDTNAPQDFIGPWVRIAGPARRMVEQTLPNASPAERQRAC
EQAAILVSLRNLESFPFVREACERGALTLHGWYFDLQAGALLAYSERADDFLPLVCPLTPEARPHRQPSNRPSIDSGQAE
MLGS

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=226, Percent_Identity=35.8407079646018, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786318, Length=204, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI25147564, Length=241, Percent_Identity=25.3112033195021, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115532990, Length=240, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26856; Mature: 26856

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEIERLLKGFERFQRRYFEARPELFDALRTGQKPQTLLIGCSDSRVDPGLLLDCDPGEL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCE
FTVRNVANLVPPCGDGASGRLHGVSAAIQFAVEQLHVVRIIVMGHAGCGGIRALLAHPQN
EEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCC
DDTNAPQDFIGPWVRIAGPARRMVEQTLPNASPAERQRACEQAAILVSLRNLESFPFVRE
CCCCCCHHHHCCHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ACERGALTLHGWYFDLQAGALLAYSERADDFLPLVCPLTPEARPHRQPSNRPSIDSGQAE
HHHCCCEEEEEEEEEECCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHH
MLGS
HCCC
>Mature Secondary Structure
MHEIERLLKGFERFQRRYFEARPELFDALRTGQKPQTLLIGCSDSRVDPGLLLDCDPGEL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCE
FTVRNVANLVPPCGDGASGRLHGVSAAIQFAVEQLHVVRIIVMGHAGCGGIRALLAHPQN
EEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCC
DDTNAPQDFIGPWVRIAGPARRMVEQTLPNASPAERQRACEQAAILVSLRNLESFPFVRE
CCCCCCHHHHCCHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ACERGALTLHGWYFDLQAGALLAYSERADDFLPLVCPLTPEARPHRQPSNRPSIDSGQAE
HHHCCCEEEEEEEEEECCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHH
MLGS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]