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The map label for this gene is aaeR [H]

Identifier: 94310832

GI number: 94310832

Start: 2061562

End: 2062536

Strand: Reverse

Name: aaeR [H]

Synonym: Rmet_1894

Alternate gene names: 94310832

Gene position: 2062536-2061562 (Counterclockwise)

Preceding gene: 94310835

Following gene: 94310831

Centisome position: 52.51

GC content: 64.62

Gene sequence:

>975_bases
ATGCGTAAGAATCTCGACTATGGATTGCTCCATGCGATGACAGCGTTTCTGCGGGTCGTCGATGCGGGCAGTTTTACGGC
CGCCGCCGCCCAAATGGCGCTCACGACGGCGCAGGTCTCGCGGCTGGTTTCCGAGTTGGAAAAGCGCCTGCAGGCCAAGC
TTCTGCAACGGACAACCCGCAGGCTGGCGCTGACCAGCGTCGGCGAGCGGTATGCTGACCAGTGCCGGAGCATTCTCGAG
CTGGTGGCCGAGGCGGAAAGCGGGGTGGGCGGCGCAAATGTCGAACCAGACGGACGGCTCAGGGTGCGTTGCATGGCCGC
GTTTGGCGAACGCTATGTGGTCCCGCTTGTGTCGATGTACTGCGCGAGGTATCCGAAGGTGGCCGTGGAGTACGGCACGT
CCCAATACGCCCCGGACCTGATTGCCGAAGGCGTGGACGCCAGCGTCTACCTGGCGCAACGGCTCTCCGATTCGAACCTG
GTGGCGCAGGCCCTTGGGGAAACCTACGGTTTGCTGTGCGCGGCGCCGTCCTATCTGAAGCGGCGCGGCACGCCGAAATC
CGTTGAGGAACTTGCAGCACATGCCTGTCTGCGCATCGCCAACCCGTCCACGACGCCCGATTGGACGCTGACGGACGGCA
CACGGAGCTTCACACTGGACGCGGGCGGCCCGCTGGTGGGTGACAACCCCGGCGTTGTCCTCCACGCCGCGAGCAGCGGG
CTGGGCATTGCGCTGCTGCCGATCTTTTCGGCTGTGGACCACATCCGCAACGGCGAACTACGCGTCGTACTGCCCGCGTG
GCGCTCCCCGGCTATCGGCGTCTACTTGATGCTGCCGTCGCGGAAGTTTCTTGAGGCGAAAACGCGCGCGTGGATCGAAT
TGCTGAAGACCGAACTGCCGACTGCGCTGCAGCGAGATGCCGGTCATCCTGCAGCAGCGACGAGGGCCAAACCGCGTCGA
TACTCGTCTCGCTGA

Upstream 100 bases:

>100_bases
TTCGTAGCAGGGCAACGAGGTTGTGCAACCGAGCACGGATCGATAGTAGAAACTCCGATTCGATGTAAAAATACAGCCAA
CTCAGAAACTCTGTTACGTC

Downstream 100 bases:

>100_bases
GCGGTAGCAACCGTTTGCACGTCGGTGTGTGGCGAAAGGTTAGGCCGAACTTTGCTGCAGTTCGCTGACGAGCTTGGCGA
TGCGACGCTGCCGCGTCTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRKNLDYGLLHAMTAFLRVVDAGSFTAAAAQMALTTAQVSRLVSELEKRLQAKLLQRTTRRLALTSVGERYADQCRSILE
LVAEAESGVGGANVEPDGRLRVRCMAAFGERYVVPLVSMYCARYPKVAVEYGTSQYAPDLIAEGVDASVYLAQRLSDSNL
VAQALGETYGLLCAAPSYLKRRGTPKSVEELAAHACLRIANPSTTPDWTLTDGTRSFTLDAGGPLVGDNPGVVLHAASSG
LGIALLPIFSAVDHIRNGELRVVLPAWRSPAIGVYLMLPSRKFLEAKTRAWIELLKTELPTALQRDAGHPAAATRAKPRR
YSSR

Sequences:

>Translated_324_residues
MRKNLDYGLLHAMTAFLRVVDAGSFTAAAAQMALTTAQVSRLVSELEKRLQAKLLQRTTRRLALTSVGERYADQCRSILE
LVAEAESGVGGANVEPDGRLRVRCMAAFGERYVVPLVSMYCARYPKVAVEYGTSQYAPDLIAEGVDASVYLAQRLSDSNL
VAQALGETYGLLCAAPSYLKRRGTPKSVEELAAHACLRIANPSTTPDWTLTDGTRSFTLDAGGPLVGDNPGVVLHAASSG
LGIALLPIFSAVDHIRNGELRVVLPAWRSPAIGVYLMLPSRKFLEAKTRAWIELLKTELPTALQRDAGHPAAATRAKPRR
YSSR
>Mature_324_residues
MRKNLDYGLLHAMTAFLRVVDAGSFTAAAAQMALTTAQVSRLVSELEKRLQAKLLQRTTRRLALTSVGERYADQCRSILE
LVAEAESGVGGANVEPDGRLRVRCMAAFGERYVVPLVSMYCARYPKVAVEYGTSQYAPDLIAEGVDASVYLAQRLSDSNL
VAQALGETYGLLCAAPSYLKRRGTPKSVEELAAHACLRIANPSTTPDWTLTDGTRSFTLDAGGPLVGDNPGVVLHAASSG
LGIALLPIFSAVDHIRNGELRVVLPAWRSPAIGVYLMLPSRKFLEAKTRAWIELLKTELPTALQRDAGHPAAATRAKPRR
YSSR

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=33.1010452961672, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=33.5570469798658, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=30.2405498281787, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=27.8169014084507, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=28.6206896551724, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=25.4180602006689, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=25.7839721254355, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788706, Length=240, Percent_Identity=23.3333333333333, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35054; Mature: 35054

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLDYGLLHAMTAFLRVVDAGSFTAAAAQMALTTAQVSRLVSELEKRLQAKLLQRTTR
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLALTSVGERYADQCRSILELVAEAESGVGGANVEPDGRLRVRCMAAFGERYVVPLVSMY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHCCHHHHHHHHHH
CARYPKVAVEYGTSQYAPDLIAEGVDASVYLAQRLSDSNLVAQALGETYGLLCAAPSYLK
HHHCCCEEEECCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
RRGTPKSVEELAAHACLRIANPSTTPDWTLTDGTRSFTLDAGGPLVGDNPGVVLHAASSG
HCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCEEEEECCCC
LGIALLPIFSAVDHIRNGELRVVLPAWRSPAIGVYLMLPSRKFLEAKTRAWIELLKTELP
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
TALQRDAGHPAAATRAKPRRYSSR
HHHHHCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MRKNLDYGLLHAMTAFLRVVDAGSFTAAAAQMALTTAQVSRLVSELEKRLQAKLLQRTTR
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLALTSVGERYADQCRSILELVAEAESGVGGANVEPDGRLRVRCMAAFGERYVVPLVSMY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHCCHHHHHHHHHH
CARYPKVAVEYGTSQYAPDLIAEGVDASVYLAQRLSDSNLVAQALGETYGLLCAAPSYLK
HHHCCCEEEECCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
RRGTPKSVEELAAHACLRIANPSTTPDWTLTDGTRSFTLDAGGPLVGDNPGVVLHAASSG
HCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCEEEEECCCC
LGIALLPIFSAVDHIRNGELRVVLPAWRSPAIGVYLMLPSRKFLEAKTRAWIELLKTELP
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
TALQRDAGHPAAATRAKPRRYSSR
HHHHHCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]