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The map label for this gene is ppiD [H]

Identifier: 94310820

GI number: 94310820

Start: 2044208

End: 2046151

Strand: Reverse

Name: ppiD [H]

Synonym: Rmet_1882

Alternate gene names: 94310820

Gene position: 2046151-2044208 (Counterclockwise)

Preceding gene: 94310821

Following gene: 94310818

Centisome position: 52.09

GC content: 61.93

Gene sequence:

>1944_bases
ATGCTTGATTTCGTACGCAACAACCGGCGCCTGATGCTCCTTCTGCTGCTGGTGCTTGTCTTCCCGTCGTTCGTATTCTT
CGGCGTGGAGAGCTATTCGCGCTTCATGGACAGCTCGCACGATGCTGCCAAGGTCGACGGCCGGGCCATCACCGTGCAGG
AAGTCGACAATGTGGTGCGCGACCAGAGCGAACGGATGCGCCAGATGCTGGGCAACAACTACGATCCGCGCATGTTCGAA
GGCCCTGCCGCGCGGCAGGCCGTGCTGGACCAGTTGATCCAGCAGCGTGTTATTTCGGAAGCCACTCAGAAGAAGCACCT
GACGGTTTCCGATGCGCAGATCGCTGCTGCGATCCAGAGCATTCCCGCCATCGCCCAGCTTCGCACGGCGGACGGCAAGT
TCGACGAGAAGGCCTACGTGCAGCTGCTGGCGGCGCAAGGTATGACGCCCGAGCAGCTCGACGCACGGATGCGTTTCGAA
CTCTCCACGCAGCAACTGGGTGGTGCCATCGGTACGACAGCTTTCGTGCCGAAGTCGCTGCTCGATCGCCTGATCGCGAT
TCGCGACCAGCAGCGTGATGTGCAGGCCATCGTGATCAAGCCGGCCGATTTCACGGCCAAGGTGACGCCGGACGCCGCCG
CGCTGAAGGCCTACTACGAGTCCCATCTGGCAGCGTACACGATGCCCGAGCAGGCCAAGGTCGAGTATCTGGTGCTGTCG
GGTGATGCCCTGGCTGCCAGCCAGACGATCACCCCCGATCAGTTGAAGTCGTATTACGACAGCAACATACAACGTTTCCA
TACTGACGAGCAACGTCGCGCCAGCCACATCCTGATCGCCGCGCCGAAGGATGGCAAGGAGGCAGACCGCAAGGCCGCCA
AGGAGAAGGCCGAGAAGCTGCTGGAGGACCTGCGCAAGCATCCAGACACGTTCGCCGATGTTGCGAAGAAGAACTCGCAG
GATCCTGGTTCGGCGGAGAAGGGCGGCGACCTCGGCTTCATGGGTCGTGGTGCCCTGGTCAAGCCGTTTGAAGACGCGAT
GTTTGCGCTCAAGGATGGCCAGATCAGCGATGTTGTGGAAACCGATTACGGCTATCACATCATCAAGCTGACGGGTATCA
AGCCGGCAGCGACCGAGCCGCTCGAGGCAGTGCGTCCCGAACTCGAGATCGAACTCAAGAAGCAGCTTGCCGCGAAGGCG
TATACCGAGCAGGCCGATGCGTTCGGCAACATGGTGTACGAGCAGTCCGAGAGCCTCAAGCCCGCCGCCGACAAGTTCAA
GCTGACGATCCAGACTGCGGACAATGTCACGCGTACGCCGAATCCGGTGTTGGGCAAGGACAACCCGCTCAATAACGAGA
AGGTGCTCAAGGCGCTGTTCAGCGATGACGCCATCAAGAACAAGCGCAATACGGAAGCCGTGCAAGTCGGCCCGACTACG
CTGGTGTCGGCGCGCATCGTCGACTATCGCCCGGCCGCCGCGCGCAAGTTCGAAGAGGTAGAGGCGCTGGTGCGTCAGGC
CTACGTCGCACAGCAGGCGGCGGAACTGGCACGCAAGGATGGCGAAGCCCGTCTTGATGCCTTGAAGAAGAGCGGCAGCG
CTGATGGCTTCGGCTCGATGGTGACCGTGTCGCGTGCCAAGGCTGATGGCGTGTCGCCGAAGGCTGTCGATTCGATCATG
CGTGCCGATGCCTCGAAGCTGCCTTCGCTCGTGGGTGTGGACCTCGGCGCGGATGGGTACGCGATCTACCGTATCGCCAA
GGTTGGCACGCCGCCGCAGGCCAACGCAAACCAGCGTGAGGCTGACGCGCAGCAACTGGGCCAGATGGCCGGCCAGACGG
AACTGGCAGCGTTCTATGACGTGCTCAAGGCCGGTGCGAAGGTGAAGATCCTGCATCCGGCCAAGACGGACGACGCGGCA
GCGAGCGCACCTGCTGCACACTGA

Upstream 100 bases:

>100_bases
TTTCGCATGATCTCTCGACGCACATTCAAGCAGTACAACTCCTCGCTTTTGATAGAATCGCAAGGTTTGACTTTCGAGCC
ACCCCTTTAACCGGATCAGC

Downstream 100 bases:

>100_bases
CGCGACGTCACCTGCGATGTAAAGAAGCCCCTGCGGTTGCGAGCCTGCAGGGGCTTTTTTGCATGTGGTCTTGCCGATCA
GCTCGGGATGCCGTGGTGCG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDAAKVDGRAITVQEVDNVVRDQSERMRQMLGNNYDPRMFE
GPAARQAVLDQLIQQRVISEATQKKHLTVSDAQIAAAIQSIPAIAQLRTADGKFDEKAYVQLLAAQGMTPEQLDARMRFE
LSTQQLGGAIGTTAFVPKSLLDRLIAIRDQQRDVQAIVIKPADFTAKVTPDAAALKAYYESHLAAYTMPEQAKVEYLVLS
GDALAASQTITPDQLKSYYDSNIQRFHTDEQRRASHILIAAPKDGKEADRKAAKEKAEKLLEDLRKHPDTFADVAKKNSQ
DPGSAEKGGDLGFMGRGALVKPFEDAMFALKDGQISDVVETDYGYHIIKLTGIKPAATEPLEAVRPELEIELKKQLAAKA
YTEQADAFGNMVYEQSESLKPAADKFKLTIQTADNVTRTPNPVLGKDNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPTT
LVSARIVDYRPAAARKFEEVEALVRQAYVAQQAAELARKDGEARLDALKKSGSADGFGSMVTVSRAKADGVSPKAVDSIM
RADASKLPSLVGVDLGADGYAIYRIAKVGTPPQANANQREADAQQLGQMAGQTELAAFYDVLKAGAKVKILHPAKTDDAA
ASAPAAH

Sequences:

>Translated_647_residues
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDAAKVDGRAITVQEVDNVVRDQSERMRQMLGNNYDPRMFE
GPAARQAVLDQLIQQRVISEATQKKHLTVSDAQIAAAIQSIPAIAQLRTADGKFDEKAYVQLLAAQGMTPEQLDARMRFE
LSTQQLGGAIGTTAFVPKSLLDRLIAIRDQQRDVQAIVIKPADFTAKVTPDAAALKAYYESHLAAYTMPEQAKVEYLVLS
GDALAASQTITPDQLKSYYDSNIQRFHTDEQRRASHILIAAPKDGKEADRKAAKEKAEKLLEDLRKHPDTFADVAKKNSQ
DPGSAEKGGDLGFMGRGALVKPFEDAMFALKDGQISDVVETDYGYHIIKLTGIKPAATEPLEAVRPELEIELKKQLAAKA
YTEQADAFGNMVYEQSESLKPAADKFKLTIQTADNVTRTPNPVLGKDNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPTT
LVSARIVDYRPAAARKFEEVEALVRQAYVAQQAAELARKDGEARLDALKKSGSADGFGSMVTVSRAKADGVSPKAVDSIM
RADASKLPSLVGVDLGADGYAIYRIAKVGTPPQANANQREADAQQLGQMAGQTELAAFYDVLKAGAKVKILHPAKTDDAA
ASAPAAH
>Mature_647_residues
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDAAKVDGRAITVQEVDNVVRDQSERMRQMLGNNYDPRMFE
GPAARQAVLDQLIQQRVISEATQKKHLTVSDAQIAAAIQSIPAIAQLRTADGKFDEKAYVQLLAAQGMTPEQLDARMRFE
LSTQQLGGAIGTTAFVPKSLLDRLIAIRDQQRDVQAIVIKPADFTAKVTPDAAALKAYYESHLAAYTMPEQAKVEYLVLS
GDALAASQTITPDQLKSYYDSNIQRFHTDEQRRASHILIAAPKDGKEADRKAAKEKAEKLLEDLRKHPDTFADVAKKNSQ
DPGSAEKGGDLGFMGRGALVKPFEDAMFALKDGQISDVVETDYGYHIIKLTGIKPAATEPLEAVRPELEIELKKQLAAKA
YTEQADAFGNMVYEQSESLKPAADKFKLTIQTADNVTRTPNPVLGKDNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPTT
LVSARIVDYRPAAARKFEEVEALVRQAYVAQQAAELARKDGEARLDALKKSGSADGFGSMVTVSRAKADGVSPKAVDSIM
RADASKLPSLVGVDLGADGYAIYRIAKVGTPPQANANQREADAQQLGQMAGQTELAAFYDVLKAGAKVKILHPAKTDDAA
ASAPAAH

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=651, Percent_Identity=27.9569892473118, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786238, Length=78, Percent_Identity=42.3076923076923, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322478, Length=108, Percent_Identity=37.962962962963, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 70519; Mature: 70519

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDAAKVDGRAITVQEVDNVVR
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
DQSERMRQMLGNNYDPRMFEGPAARQAVLDQLIQQRVISEATQKKHLTVSDAQIAAAIQS
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
IPAIAQLRTADGKFDEKAYVQLLAAQGMTPEQLDARMRFELSTQQLGGAIGTTAFVPKSL
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHEEECHHHHCCHHHHHHHHHHHH
LDRLIAIRDQQRDVQAIVIKPADFTAKVTPDAAALKAYYESHLAAYTMPEQAKVEYLVLS
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GDALAASQTITPDQLKSYYDSNIQRFHTDEQRRASHILIAAPKDGKEADRKAAKEKAEKL
CCCHHCCCCCCHHHHHHHHHCCHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
LEDLRKHPDTFADVAKKNSQDPGSAEKGGDLGFMGRGALVKPFEDAMFALKDGQISDVVE
HHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHH
TDYGYHIIKLTGIKPAATEPLEAVRPELEIELKKQLAAKAYTEQADAFGNMVYEQSESLK
CCCCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAADKFKLTIQTADNVTRTPNPVLGKDNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPTT
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHH
LVSARIVDYRPAAARKFEEVEALVRQAYVAQQAAELARKDGEARLDALKKSGSADGFGSM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCE
VTVSRAKADGVSPKAVDSIMRADASKLPSLVGVDLGADGYAIYRIAKVGTPPQANANQRE
EEEEHHHCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCEEEEEEEECCCCCCCCCCHHH
ADAQQLGQMAGQTELAAFYDVLKAGAKVKILHPAKTDDAAASAPAAH
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDAAKVDGRAITVQEVDNVVR
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
DQSERMRQMLGNNYDPRMFEGPAARQAVLDQLIQQRVISEATQKKHLTVSDAQIAAAIQS
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
IPAIAQLRTADGKFDEKAYVQLLAAQGMTPEQLDARMRFELSTQQLGGAIGTTAFVPKSL
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHEEECHHHHCCHHHHHHHHHHHH
LDRLIAIRDQQRDVQAIVIKPADFTAKVTPDAAALKAYYESHLAAYTMPEQAKVEYLVLS
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GDALAASQTITPDQLKSYYDSNIQRFHTDEQRRASHILIAAPKDGKEADRKAAKEKAEKL
CCCHHCCCCCCHHHHHHHHHCCHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
LEDLRKHPDTFADVAKKNSQDPGSAEKGGDLGFMGRGALVKPFEDAMFALKDGQISDVVE
HHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHH
TDYGYHIIKLTGIKPAATEPLEAVRPELEIELKKQLAAKAYTEQADAFGNMVYEQSESLK
CCCCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAADKFKLTIQTADNVTRTPNPVLGKDNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPTT
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHH
LVSARIVDYRPAAARKFEEVEALVRQAYVAQQAAELARKDGEARLDALKKSGSADGFGSM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCE
VTVSRAKADGVSPKAVDSIMRADASKLPSLVGVDLGADGYAIYRIAKVGTPPQANANQRE
EEEEHHHCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCEEEEEEEECCCCCCCCCCHHH
ADAQQLGQMAGQTELAAFYDVLKAGAKVKILHPAKTDDAAASAPAAH
HHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]