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The map label for this gene is ttuB [H]

Identifier: 94310776

GI number: 94310776

Start: 1992435

End: 1993793

Strand: Direct

Name: ttuB [H]

Synonym: Rmet_1838

Alternate gene names: 94310776

Gene position: 1992435-1993793 (Clockwise)

Preceding gene: 335055550

Following gene: 94310777

Centisome position: 50.72

GC content: 64.02

Gene sequence:

>1359_bases
ATGACCGCTTCCAACCCCGCGGTGGGGACCCCTGTTGCCGACACCCGGCTGGACGCCGACGGCACCATCGAGAAACGCGC
CTACAACAAGGTGTTCTGGCGCATCATGCCGTTCCTGATGCTCTGCTACGTGATCGCGTATCTCGACCGCGTCAACGTCG
GCTTTGCCAAGTTGCAGATGGCGCAGGACCTGCAGTTCTCGGAAACCGTGTTCGGCCTTGGCGCTGGCCTGTTCTTCATC
GGCTACTTCCTGTTCGAGGTGCCCAGCAACCTGCTGATGCACCACATCGGCGCGCGCATTTGGATCGCGCGGATCATGAT
CACCTGGGGCATCATCTCGGCCGCCTTCGTGTTCGTGCAGACGCCAACGCAGTTCTACGTCATGCGCTTCCTGCTGGGCC
TGGCCGAAGCGGGCTTCTATCCGGGCGTGATCCTGTACCTGACGTACTGGTATCCGTCGCACCGCCGCGCCAAGATGATC
GCGCTGTTCATGTCGGGCATTCCAGTGGCCGGCATGTTCGGCAATCCGCTGTCAGGCTGGATCATGGACGCGTTCCACAA
CACCCATGGCTGGACCGGCTGGCAATGGATGTTCCTCATCGAGGCCCTGCCCGCCTTCGCGATCGGCATCGCTACGATCT
TCGTGCTGCGCGATGGCATCGACCGCGCTCCGTGGCTCAGCCCCGATGAAAAGCACGTGCTCAAGCGCAATATCGAGGAC
GACGAACGCGCCGCGTCGGCTGCGGCCACCACGGGCGGCCAACGCCACGTGCATTCGCTGGGCGCCGTGTTCCGCGACAG
CCGTGTTTGGTGGATGTGCCTGATCTACTTCTGCTTCGTGACCGGCCAGTACGCGCTGACGTTCTGGATGCCGACGCTGG
TCAAGGCCAGCGGCGTGACAGGCAACTTCAACATCGGCCTGCTGTCCGCCATCCCGTTCCTCTGCGCCATCGTCGTCATG
AACATCCTGGGCCACAGCGCCGACGCGCGCCGCGAGCGCCGCTGGCACCTGATCGTGCCGGCACTGATGGGTGCCACGGG
CTTTGCGATTGCGGCGTCGTTCACCCACAATACGACCGTGGCCATCGCAGCGCTGTCGCTGGCCGCCGCTGGCGTGCTGA
CCTGCGCCCCGCTGTTCTGGTCATTGCCGACCGCATTCCTGAGCGGCATCGCCGCCGCCTCGGGTATCGCCGTGGTGAAC
TCTGTCGGCAATCTGGCAGGCTTCGTGTCGCCGTATATGGTCGGCGCGCTCAAGGACATGACGCAAAGCACGCAATTGCC
GATGTACGTGCTGTCGGCGATCCTGGTCGTGGGCGCCCTGCTGGTCTGGCTGACCCCGGCGAAGCTCGTCAATCGCTGA

Upstream 100 bases:

>100_bases
AACTCCGCAAAACAAAGCCCCTGCCCTCTCCCAAACCCTCTCCCGCCATGCGAGAGAGGGAGCAAACCGGCTGCATTTTC
AATACACGTGGAGACTTCCA

Downstream 100 bases:

>100_bases
TATCGAATCTGAGGCTCAAGGAGACCTGACATGCCGCGCTTCGCCGCGAACCTTTCAATGATGTACACGGAGCACGACTT
TCTGGACCGCTTTGCCGCCG

Product: MFS transporter, ACS family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTASNPAVGTPVADTRLDADGTIEKRAYNKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMAQDLQFSETVFGLGAGLFFI
GYFLFEVPSNLLMHHIGARIWIARIMITWGIISAAFVFVQTPTQFYVMRFLLGLAEAGFYPGVILYLTYWYPSHRRAKMI
ALFMSGIPVAGMFGNPLSGWIMDAFHNTHGWTGWQWMFLIEALPAFAIGIATIFVLRDGIDRAPWLSPDEKHVLKRNIED
DERAASAAATTGGQRHVHSLGAVFRDSRVWWMCLIYFCFVTGQYALTFWMPTLVKASGVTGNFNIGLLSAIPFLCAIVVM
NILGHSADARRERRWHLIVPALMGATGFAIAASFTHNTTVAIAALSLAAAGVLTCAPLFWSLPTAFLSGIAAASGIAVVN
SVGNLAGFVSPYMVGALKDMTQSTQLPMYVLSAILVVGALLVWLTPAKLVNR

Sequences:

>Translated_452_residues
MTASNPAVGTPVADTRLDADGTIEKRAYNKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMAQDLQFSETVFGLGAGLFFI
GYFLFEVPSNLLMHHIGARIWIARIMITWGIISAAFVFVQTPTQFYVMRFLLGLAEAGFYPGVILYLTYWYPSHRRAKMI
ALFMSGIPVAGMFGNPLSGWIMDAFHNTHGWTGWQWMFLIEALPAFAIGIATIFVLRDGIDRAPWLSPDEKHVLKRNIED
DERAASAAATTGGQRHVHSLGAVFRDSRVWWMCLIYFCFVTGQYALTFWMPTLVKASGVTGNFNIGLLSAIPFLCAIVVM
NILGHSADARRERRWHLIVPALMGATGFAIAASFTHNTTVAIAALSLAAAGVLTCAPLFWSLPTAFLSGIAAASGIAVVN
SVGNLAGFVSPYMVGALKDMTQSTQLPMYVLSAILVVGALLVWLTPAKLVNR
>Mature_451_residues
TASNPAVGTPVADTRLDADGTIEKRAYNKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMAQDLQFSETVFGLGAGLFFIG
YFLFEVPSNLLMHHIGARIWIARIMITWGIISAAFVFVQTPTQFYVMRFLLGLAEAGFYPGVILYLTYWYPSHRRAKMIA
LFMSGIPVAGMFGNPLSGWIMDAFHNTHGWTGWQWMFLIEALPAFAIGIATIFVLRDGIDRAPWLSPDEKHVLKRNIEDD
ERAASAAATTGGQRHVHSLGAVFRDSRVWWMCLIYFCFVTGQYALTFWMPTLVKASGVTGNFNIGLLSAIPFLCAIVVMN
ILGHSADARRERRWHLIVPALMGATGFAIAASFTHNTTVAIAALSLAAAGVLTCAPLFWSLPTAFLSGIAAASGIAVVNS
VGNLAGFVSPYMVGALKDMTQSTQLPMYVLSAILVVGALLVWLTPAKLVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI21322234, Length=441, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI6912666, Length=406, Percent_Identity=22.6600985221675, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI9966811, Length=450, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87082071, Length=426, Percent_Identity=36.6197183098592, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=23.7327188940092, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI2367379, Length=445, Percent_Identity=23.1460674157303, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=22.4586288416076, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789152, Length=435, Percent_Identity=23.6781609195402, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=231, Percent_Identity=25.974025974026, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=332, Percent_Identity=22.5903614457831, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=212, Percent_Identity=25.9433962264151, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=255, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584153, Length=371, Percent_Identity=21.832884097035, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583789, Length=384, Percent_Identity=24.7395833333333, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641682, Length=415, Percent_Identity=22.6506024096386, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49628; Mature: 49497

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCHHHHHHHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure 
TASNPAVGTPVADTRLDADGTIEKRAYNKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQM
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH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HHHCCCHHHHHHHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]