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The map label for this gene is ycdJ [C]

Identifier: 94310698

GI number: 94310698

Start: 1911300

End: 1912208

Strand: Reverse

Name: ycdJ [C]

Synonym: Rmet_1760

Alternate gene names: 94310698

Gene position: 1912208-1911300 (Counterclockwise)

Preceding gene: 94310700

Following gene: 94310694

Centisome position: 48.68

GC content: 61.17

Gene sequence:

>909_bases
ATGCGAAGACTCCTTGCAGCCGTCGTATTCATGCTTGCCATGGTCCAGCCGTTGCAAGCACAGGTGAAGCCATTTCCGCC
AGGTTTCCGGCACCAGAATATCCAGACCGAGGGCGCGACGCTGTATGTGCGGGTGGGTGGCAGCGGGCCTGCCGTGGTCC
TGCTGCACGGTTTTGGCGATACAGGGGACATGTGGGCGCCACTGGCCGCCGAACTGGCACGCACCCATACGGTGGTGGTG
CCGGATCTGCGCGGAATGGGGCTGTCATCGCATCCTGACGGCGGCTACGACAAGCGCACACAGGCTGGGGACATCCGGTC
GGTGCTGGCGCAACTGAACATCGACCAAGCGGACGTGGTCGGCCACGACATCGGCACGATGGTCGCCTATGCCTATGCGG
CGCGCTACCCGGACAAAACGAAAAGGCTGATCGTCATGGACGCGCCAGTGCCAGGAGTCCCGCCGTGGGAACAGATCGTC
CGAATGCCAGCGCTCTGGCATTTCTCCTTCGGCGGCCCGGATGCGGAGCGGCTGGTAAAAGGCCGGGAACGCATCTACCT
GGACAGGTTCTGGAACGAGTTCGCCGGAGACCCTTCGAAGATCGACGAAGCCACACGGGTTCACTATTCCCGGCTCTATG
CCAAGCCGGGCGCGATGCATTCAGCGTTCGCGCAATTCCTCTCAATTCCGCAAGACGCCGAGGACAATCAGAAATCGCTG
GCGACCAAGCTGACCATGCCAGTACTGGCGATTGGCGGCGCGAAGTCCTTTGGCCAGAACGAAGCGATCGTCATGCGCAA
TGCGGCCACCAACGTGAAAGAACTAGTCATTCCGAATGCCGGGCATTGGCTGATGGAAGAACAACCACAGGCCACAGTGG
GCGCGATCGTCGATTTCCTCGGACAATAG

Upstream 100 bases:

>100_bases
TTGCACTACGCTTCAGGGGGCTCGTGCGAAGCGAAGCCATTCAGGCGATCCGATAACCGTGACTTTCCGACACCGGCCAC
TCCCGCCCCCGGAGAAAAAC

Downstream 100 bases:

>100_bases
CCAGAAGATCGCTGGCGTCCTGATGCAGCTGAACTGCAATAGAGGTGGGGCGGGTGAACGGCGGCGCTCTCCGCGTTCGA
GTCAGGCGGCGGCAATGGCA

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRRLLAAVVFMLAMVQPLQAQVKPFPPGFRHQNIQTEGATLYVRVGGSGPAVVLLHGFGDTGDMWAPLAAELARTHTVVV
PDLRGMGLSSHPDGGYDKRTQAGDIRSVLAQLNIDQADVVGHDIGTMVAYAYAARYPDKTKRLIVMDAPVPGVPPWEQIV
RMPALWHFSFGGPDAERLVKGRERIYLDRFWNEFAGDPSKIDEATRVHYSRLYAKPGAMHSAFAQFLSIPQDAEDNQKSL
ATKLTMPVLAIGGAKSFGQNEAIVMRNAATNVKELVIPNAGHWLMEEQPQATVGAIVDFLGQ

Sequences:

>Translated_302_residues
MRRLLAAVVFMLAMVQPLQAQVKPFPPGFRHQNIQTEGATLYVRVGGSGPAVVLLHGFGDTGDMWAPLAAELARTHTVVV
PDLRGMGLSSHPDGGYDKRTQAGDIRSVLAQLNIDQADVVGHDIGTMVAYAYAARYPDKTKRLIVMDAPVPGVPPWEQIV
RMPALWHFSFGGPDAERLVKGRERIYLDRFWNEFAGDPSKIDEATRVHYSRLYAKPGAMHSAFAQFLSIPQDAEDNQKSL
ATKLTMPVLAIGGAKSFGQNEAIVMRNAATNVKELVIPNAGHWLMEEQPQATVGAIVDFLGQ
>Mature_302_residues
MRRLLAAVVFMLAMVQPLQAQVKPFPPGFRHQNIQTEGATLYVRVGGSGPAVVLLHGFGDTGDMWAPLAAELARTHTVVV
PDLRGMGLSSHPDGGYDKRTQAGDIRSVLAQLNIDQADVVGHDIGTMVAYAYAARYPDKTKRLIVMDAPVPGVPPWEQIV
RMPALWHFSFGGPDAERLVKGRERIYLDRFWNEFAGDPSKIDEATRVHYSRLYAKPGAMHSAFAQFLSIPQDAEDNQKSL
ATKLTMPVLAIGGAKSFGQNEAIVMRNAATNVKELVIPNAGHWLMEEQPQATVGAIVDFLGQ

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=293, Percent_Identity=26.2798634812287, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=278, Percent_Identity=25.1798561151079, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 33022; Mature: 33022

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLAAVVFMLAMVQPLQAQVKPFPPGFRHQNIQTEGATLYVRVGGSGPAVVLLHGFGD
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCC
TGDMWAPLAAELARTHTVVVPDLRGMGLSSHPDGGYDKRTQAGDIRSVLAQLNIDQADVV
CCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
GHDIGTMVAYAYAARYPDKTKRLIVMDAPVPGVPPWEQIVRMPALWHFSFGGPDAERLVK
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCEEEECCCCCCHHHHHH
GRERIYLDRFWNEFAGDPSKIDEATRVHYSRLYAKPGAMHSAFAQFLSIPQDAEDNQKSL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHH
ATKLTMPVLAIGGAKSFGQNEAIVMRNAATNVKELVIPNAGHWLMEEQPQATVGAIVDFL
HHHHHHHHEEECCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
GQ
CC
>Mature Secondary Structure
MRRLLAAVVFMLAMVQPLQAQVKPFPPGFRHQNIQTEGATLYVRVGGSGPAVVLLHGFGD
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCC
TGDMWAPLAAELARTHTVVVPDLRGMGLSSHPDGGYDKRTQAGDIRSVLAQLNIDQADVV
CCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
GHDIGTMVAYAYAARYPDKTKRLIVMDAPVPGVPPWEQIVRMPALWHFSFGGPDAERLVK
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCEEEECCCCCCHHHHHH
GRERIYLDRFWNEFAGDPSKIDEATRVHYSRLYAKPGAMHSAFAQFLSIPQDAEDNQKSL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHH
ATKLTMPVLAIGGAKSFGQNEAIVMRNAATNVKELVIPNAGHWLMEEQPQATVGAIVDFL
HHHHHHHHEEECCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
GQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]