Click here to switch to the map view.

The map label for this gene is fnr [H]

Identifier: 94310632

GI number: 94310632

Start: 1832542

End: 1833276

Strand: Reverse

Name: fnr [H]

Synonym: Rmet_1692

Alternate gene names: 94310632

Gene position: 1833276-1832542 (Counterclockwise)

Preceding gene: 94310633

Following gene: 335055544

Centisome position: 46.67

GC content: 59.05

Gene sequence:

>735_bases
ATGCCTCGCTGCTCTGCATGTACCTTCGCCAGCTTTTGCCTCCCGGGTGGATTGAATCGCCGCGACATCGATCGCCTGGA
CTCCGTCGTACATGGCCGAATCAGCCTGCACAAGGGCGAATCGCTCTATCGGCTGGGTGATCCCGTGACATCCATCTATG
CAATCCGTGTCGGCACATTGAAGAGTCAGGTTTCCACCCAGGATGGACGCGTACAGATCGTTGGGTTTCATCTTCCCGGC
GAACTGGTCGGCCTCGACAGCCTCGTGTCCCCGCAATATATGTCTCACGCGGTGGCCCTCGAGGACGCCCGGCTCTGCCG
CATCAATCTGACAGCGTTGCGCGATCTGGCTGTCGCGCTGCCCGGGTTGTACAACAACATCTTGCGGCTCATGGCAAACG
AAGTCCGTCACGACCATGCCATGCTGAGAACGCTTGGGGTGCTCAATGCCGAGGAAAGGCTGATCGCGTTCCTTCTCAGT
CTTTCCGCGCGGCTGTCCGCCAGGGGCTTTGCGGCAAGCGAGTTCCAACTGCGGATGACCCGGGAGGAGATCGGCAGCTA
TCTGGGCCTGAAACTCGAGACGATCAGCCGCCTGTTCTCCAGGCTTTCGGAGACGGGACTGATCACCGTACGACACCGCA
GCGTGAAGCTCAACGATCTCAACGGACTACGCCTGATATATGAAGGATCGTCGGGCGCTCTGGCATCGTTCCAGAATCAC
TGTCTTGCGAACTGA

Upstream 100 bases:

>100_bases
CCAGGTGTCCGCCACCGCCTCTCGCCTTCCGGGTAGCCATCGCTGCCAACGGTCTGCAAGTTACGGAAATTGCGCCCCTC
TCGCATCGCCTCACTTGAAA

Downstream 100 bases:

>100_bases
AATGATTTTTGATACTGATTTATTTGCTATTGATTCTGGCATTTCACGCACTCATTAATTTTGCGCAAATGCAATATTTT
AACGTTTATTTTTCTTGTTT

Product: DNA-binding transcriptional dual regulator, global regulator of anaerobic growth

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MPRCSACTFASFCLPGGLNRRDIDRLDSVVHGRISLHKGESLYRLGDPVTSIYAIRVGTLKSQVSTQDGRVQIVGFHLPG
ELVGLDSLVSPQYMSHAVALEDARLCRINLTALRDLAVALPGLYNNILRLMANEVRHDHAMLRTLGVLNAEERLIAFLLS
LSARLSARGFAASEFQLRMTREEIGSYLGLKLETISRLFSRLSETGLITVRHRSVKLNDLNGLRLIYEGSSGALASFQNH
CLAN

Sequences:

>Translated_244_residues
MPRCSACTFASFCLPGGLNRRDIDRLDSVVHGRISLHKGESLYRLGDPVTSIYAIRVGTLKSQVSTQDGRVQIVGFHLPG
ELVGLDSLVSPQYMSHAVALEDARLCRINLTALRDLAVALPGLYNNILRLMANEVRHDHAMLRTLGVLNAEERLIAFLLS
LSARLSARGFAASEFQLRMTREEIGSYLGLKLETISRLFSRLSETGLITVRHRSVKLNDLNGLRLIYEGSSGALASFQNH
CLAN
>Mature_243_residues
PRCSACTFASFCLPGGLNRRDIDRLDSVVHGRISLHKGESLYRLGDPVTSIYAIRVGTLKSQVSTQDGRVQIVGFHLPGE
LVGLDSLVSPQYMSHAVALEDARLCRINLTALRDLAVALPGLYNNILRLMANEVRHDHAMLRTLGVLNAEERLIAFLLSL
SARLSARGFAASEFQLRMTREEIGSYLGLKLETISRLFSRLSETGLITVRHRSVKLNDLNGLRLIYEGSSGALASFQNHC
LAN

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=220, Percent_Identity=41.8181818181818, Blast_Score=196, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26902; Mature: 26770

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRCSACTFASFCLPGGLNRRDIDRLDSVVHGRISLHKGESLYRLGDPVTSIYAIRVGTL
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCEECCCCHHHEEEEEEHHH
KSQVSTQDGRVQIVGFHLPGELVGLDSLVSPQYMSHAVALEDARLCRINLTALRDLAVAL
HHHCCCCCCEEEEEEEECCCHHCCCHHHCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHH
PGLYNNILRLMANEVRHDHAMLRTLGVLNAEERLIAFLLSLSARLSARGFAASEFQLRMT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEH
REEIGSYLGLKLETISRLFSRLSETGLITVRHRSVKLNDLNGLRLIYEGSSGALASFQNH
HHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECEEEEECCCCEEEEEECCCCCHHHHHHH
CLAN
HCCC
>Mature Secondary Structure 
PRCSACTFASFCLPGGLNRRDIDRLDSVVHGRISLHKGESLYRLGDPVTSIYAIRVGTL
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCEECCCCHHHEEEEEEHHH
KSQVSTQDGRVQIVGFHLPGELVGLDSLVSPQYMSHAVALEDARLCRINLTALRDLAVAL
HHHCCCCCCEEEEEEEECCCHHCCCHHHCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHH
PGLYNNILRLMANEVRHDHAMLRTLGVLNAEERLIAFLLSLSARLSARGFAASEFQLRMT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEH
REEIGSYLGLKLETISRLFSRLSETGLITVRHRSVKLNDLNGLRLIYEGSSGALASFQNH
HHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECEEEEECCCCEEEEEECCCCCHHHHHHH
CLAN
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]