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The map label for this gene is ldcA [H]

Identifier: 94310516

GI number: 94310516

Start: 1693396

End: 1694316

Strand: Direct

Name: ldcA [H]

Synonym: Rmet_1574

Alternate gene names: 94310516

Gene position: 1693396-1694316 (Clockwise)

Preceding gene: 94310515

Following gene: 94310517

Centisome position: 43.11

GC content: 65.58

Gene sequence:

>921_bases
ATGAGCCAGCCCACCGAAGTCCGTCTCATCGCCTCATCCGGCTACCCTCACGACGTTGCCATTGCCGCCCGCGGCTGTGC
CTGGCTCAAGCACCACGGCTACCACGTCAACAATCCCGATGTGCTCGCGCGCCGCTATCTGCGATTCGGCGGTACGGATG
CGGAGCGGTTGGCCGATCTCCATGCCATCGGCACAGGTCCCGCTCGGGAGCTGACGCTGGCGGTGCGCGGCGGGTACGGC
CTGGGCCGACTGCTCGATCGCATCGAGTTCGGGCGCATCGCGGAGCAGGCCAGCGCAAGCGGCACGCCGATCGTCGGTCA
CAGCGATTTCACCGCGTTCCAGCTGGCCTATCTGGCCAAGGCTGGCGGGGTGTCGTTCGCAGGGCCGATGCTGCTCGCGG
ATTTCGGCGAGGAGCACGTCGATTCGTTCATGTGGCGGCATTTCGAGGGCATCCTGCGCGCCCCGGTCCACGACATCGAG
GTCGAGGCGGCCCAGGTGGCCGCGCCGGCAACCGTGGAAGGCACGCTCTGGGGCGGCAATCTGGCCATGCTGTGCACGCT
GCTGGGCACGCCGTACATGCCGAACATCGACGGTGGCATTCTGTTCCTGGAAGACATCAACGAGCCGCCGTACCGCGTGG
AGCGGATGTTGCTCCAGTTGCTGCACGCAGGGGTGCTGGCCCGGCAACAGGCCATCGTGCTGGGCGACTTCTCGAATTAC
CGCACCACCGACTACGACAATGGCTACAACATGGATGCCGTATTCGACTATGTGCGCGAACAGTTGCGTATTCCGGTGCT
CACGGGCCTGCCGTTCGGCCACTGCCCGCGCAAGCTGACTTTGCCGGTGGGCGGAAATGCGCGGCTGACGGCACGTGCCG
ACGGTTTCGTGCTGTCGCTGTCGGGTTATCCGACGTTGTAG

Upstream 100 bases:

>100_bases
GGGCGCGCCGCAGGGCGCAGAAAGCGGCAAGAGCCTTGCAGGTCTCGCCAGTGGACGCAGATTCGGGGAAAATTCAGGCT
TCAGACCCGAATTCCGAAAC

Downstream 100 bases:

>100_bases
GCGGCGTTGTAGTCGGCGGTCGCCCAGGGCGGCGACATGCCGCCCGCGACTTACCAGATACCCCCACGAGTGGTAAAATA
TCTGGTTATTTCCTCATTTC

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSQPTEVRLIASSGYPHDVAIAARGCAWLKHHGYHVNNPDVLARRYLRFGGTDAERLADLHAIGTGPARELTLAVRGGYG
LGRLLDRIEFGRIAEQASASGTPIVGHSDFTAFQLAYLAKAGGVSFAGPMLLADFGEEHVDSFMWRHFEGILRAPVHDIE
VEAAQVAAPATVEGTLWGGNLAMLCTLLGTPYMPNIDGGILFLEDINEPPYRVERMLLQLLHAGVLARQQAIVLGDFSNY
RTTDYDNGYNMDAVFDYVREQLRIPVLTGLPFGHCPRKLTLPVGGNARLTARADGFVLSLSGYPTL

Sequences:

>Translated_306_residues
MSQPTEVRLIASSGYPHDVAIAARGCAWLKHHGYHVNNPDVLARRYLRFGGTDAERLADLHAIGTGPARELTLAVRGGYG
LGRLLDRIEFGRIAEQASASGTPIVGHSDFTAFQLAYLAKAGGVSFAGPMLLADFGEEHVDSFMWRHFEGILRAPVHDIE
VEAAQVAAPATVEGTLWGGNLAMLCTLLGTPYMPNIDGGILFLEDINEPPYRVERMLLQLLHAGVLARQQAIVLGDFSNY
RTTDYDNGYNMDAVFDYVREQLRIPVLTGLPFGHCPRKLTLPVGGNARLTARADGFVLSLSGYPTL
>Mature_305_residues
SQPTEVRLIASSGYPHDVAIAARGCAWLKHHGYHVNNPDVLARRYLRFGGTDAERLADLHAIGTGPARELTLAVRGGYGL
GRLLDRIEFGRIAEQASASGTPIVGHSDFTAFQLAYLAKAGGVSFAGPMLLADFGEEHVDSFMWRHFEGILRAPVHDIEV
EAAQVAAPATVEGTLWGGNLAMLCTLLGTPYMPNIDGGILFLEDINEPPYRVERMLLQLLHAGVLARQQAIVLGDFSNYR
TTDYDNGYNMDAVFDYVREQLRIPVLTGLPFGHCPRKLTLPVGGNARLTARADGFVLSLSGYPTL

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=300, Percent_Identity=49.3333333333333, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33287; Mature: 33156

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTEVRLIASSGYPHDVAIAARGCAWLKHHGYHVNNPDVLARRYLRFGGTDAERLADL
CCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
HAIGTGPARELTLAVRGGYGLGRLLDRIEFGRIAEQASASGTPIVGHSDFTAFQLAYLAK
HHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHH
AGGVSFAGPMLLADFGEEHVDSFMWRHFEGILRAPVHDIEVEAAQVAAPATVEGTLWGGN
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCCEEEEEEECCC
LAMLCTLLGTPYMPNIDGGILFLEDINEPPYRVERMLLQLLHAGVLARQQAIVLGDFSNY
HHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
RTTDYDNGYNMDAVFDYVREQLRIPVLTGLPFGHCPRKLTLPVGGNARLTARADGFVLSL
CCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCEEEEEECCCEEEEE
SGYPTL
CCCCCC
>Mature Secondary Structure 
SQPTEVRLIASSGYPHDVAIAARGCAWLKHHGYHVNNPDVLARRYLRFGGTDAERLADL
CCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
HAIGTGPARELTLAVRGGYGLGRLLDRIEFGRIAEQASASGTPIVGHSDFTAFQLAYLAK
HHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHH
AGGVSFAGPMLLADFGEEHVDSFMWRHFEGILRAPVHDIEVEAAQVAAPATVEGTLWGGN
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCCEEEEEEECCC
LAMLCTLLGTPYMPNIDGGILFLEDINEPPYRVERMLLQLLHAGVLARQQAIVLGDFSNY
HHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
RTTDYDNGYNMDAVFDYVREQLRIPVLTGLPFGHCPRKLTLPVGGNARLTARADGFVLSL
CCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCEEEEEECCCEEEEE
SGYPTL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]