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The map label for this gene is tadA [H]

Identifier: 94310515

GI number: 94310515

Start: 1692830

End: 1693399

Strand: Direct

Name: tadA [H]

Synonym: Rmet_1573

Alternate gene names: 94310515

Gene position: 1692830-1693399 (Clockwise)

Preceding gene: 94310514

Following gene: 94310516

Centisome position: 43.1

GC content: 65.79

Gene sequence:

>570_bases
ATGGCAGACGTCCCCGTATTTGCCGACCCCGCGGAGCGCGACCGCTTCTACATGGCCGCCGCGCTCGACGAGGCACGGCT
GGCCGAAGCGGCCGGCGAGGTGCCGGTGGGCGCCGTGGTGGTGTGGGACGACAAGATCATCGCGCGCGGCCACAATTTGC
CGATCCGTTCGGTCGATCCGTCCGCTCATGCGGAGATGCAGGCGCTGCGCGCGGCAGCCAAGGTGCTGGGCAACTACCGG
ATGCCCGAGTGCGAGATTTACGTGACGCTTGAGCCGTGCCCGATGTGCAGTGGGGCGATTCTCCATGCGCGGCTGCGACA
CGTGGTATTTGGCGCGACCGACCCCAAGACGGGGGCGGCCGGCAGCGTGGTCGATCTGTTCGCGCAGGCCACGCTCAATC
ACCAGACCACACTCACGCGAGGCGTGATGGCTGATGAGTGTGGCCAGTTGCTGCGCGACTTTTTCGGGGCGCGCCGCAGG
GCGCAGAAAGCGGCAAGAGCCTTGCAGGTCTCGCCAGTGGACGCAGATTCGGGGAAAATTCAGGCTTCAGACCCGAATTC
CGAAACATGA

Upstream 100 bases:

>100_bases
GACCCGCCTGGTGCTGTTCGAGACGCCGAACTGCTGGGCCGAGGTCAGCGCGCCGCTCAGCCTGCCCGCGCAGGACTGAC
GCGGGACTGACAGGCGCTTC

Downstream 100 bases:

>100_bases
GCCAGCCCACCGAAGTCCGTCTCATCGCCTCATCCGGCTACCCTCACGACGTTGCCATTGCCGCCCGCGGCTGTGCCTGG
CTCAAGCACCACGGCTACCA

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MADVPVFADPAERDRFYMAAALDEARLAEAAGEVPVGAVVVWDDKIIARGHNLPIRSVDPSAHAEMQALRAAAKVLGNYR
MPECEIYVTLEPCPMCSGAILHARLRHVVFGATDPKTGAAGSVVDLFAQATLNHQTTLTRGVMADECGQLLRDFFGARRR
AQKAARALQVSPVDADSGKIQASDPNSET

Sequences:

>Translated_189_residues
MADVPVFADPAERDRFYMAAALDEARLAEAAGEVPVGAVVVWDDKIIARGHNLPIRSVDPSAHAEMQALRAAAKVLGNYR
MPECEIYVTLEPCPMCSGAILHARLRHVVFGATDPKTGAAGSVVDLFAQATLNHQTTLTRGVMADECGQLLRDFFGARRR
AQKAARALQVSPVDADSGKIQASDPNSET
>Mature_188_residues
ADVPVFADPAERDRFYMAAALDEARLAEAAGEVPVGAVVVWDDKIIARGHNLPIRSVDPSAHAEMQALRAAAKVLGNYRM
PECEIYVTLEPCPMCSGAILHARLRHVVFGATDPKTGAAGSVVDLFAQATLNHQTTLTRGVMADECGQLLRDFFGARRRA
QKAARALQVSPVDADSGKIQASDPNSET

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=155, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI145693172, Length=156, Percent_Identity=49.3589743589744, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=40.8163265306122, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17555996, Length=99, Percent_Identity=42.4242424242424, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541138, Length=145, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=37.9310344827586, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20254; Mature: 20123

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVPVFADPAERDRFYMAAALDEARLAEAAGEVPVGAVVVWDDKIIARGHNLPIRSVDP
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCCCCCCCCC
SAHAEMQALRAAAKVLGNYRMPECEIYVTLEPCPMCSGAILHARLRHVVFGATDPKTGAA
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCC
GSVVDLFAQATLNHQTTLTRGVMADECGQLLRDFFGARRRAQKAARALQVSPVDADSGKI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
QASDPNSET
EECCCCCCC
>Mature Secondary Structure 
ADVPVFADPAERDRFYMAAALDEARLAEAAGEVPVGAVVVWDDKIIARGHNLPIRSVDP
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCCCCCCCCC
SAHAEMQALRAAAKVLGNYRMPECEIYVTLEPCPMCSGAILHARLRHVVFGATDPKTGAA
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCC
GSVVDLFAQATLNHQTTLTRGVMADECGQLLRDFFGARRRAQKAARALQVSPVDADSGKI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
QASDPNSET
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]