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The map label for this gene is cbbG1 [H]

Identifier: 94310457

GI number: 94310457

Start: 1636839

End: 1637846

Strand: Direct

Name: cbbG1 [H]

Synonym: Rmet_1515

Alternate gene names: 94310457

Gene position: 1636839-1637846 (Clockwise)

Preceding gene: 94310456

Following gene: 94310458

Centisome position: 41.67

GC content: 64.98

Gene sequence:

>1008_bases
ATGACTATTCGCATCGGAATCAACGGCTTCGGTCGCATCGGCCGCATGGTGTTTCGCGCCGCCGTGCAGGACTTCAAGAA
CGACATCGAGGTGGTCGCGATCAACGACCTGCTCGAACCCGACTATCTCGCGTACATGCTGCGGTACGACAGCGTGCACG
GCCGCTTCAAGGGCGAAGTGGTCGTCGATGGCGGCACGCTGGTCGTCAACGGCCGCAAGATCCGGCTCACCGCGGTAAAG
GATCCCGCCGCGCTCGCCTGGGGCGATGTCGGCGTCGACGTGGTCGTCGAGTCGACGGGCCTGTTCCTGACGCACGACAC
CTGCCAGAAGCACCTCGACGCTGGCGCCAGGAAGGTGATCCAGAGCGCACCCAGCAAGGACGACACGCCGATGTTCGTCT
ATGGCGTCAACCACACCCAGTACGCCGGTGAGAAGATCGTCAGCAACGCGAGCTGCACCACGAACTGCCTGGCGCCGGTG
GCCAAGGTGCTCAACGACAGTTTCGGCATCAAGCGCGGCATGATGACCACCGTGCACGCCGCCACCGCCACGCAGAAGAC
CGTGGACGGCCCGAGCAACAAGGACTGGCGCGGCGGCCGCGGCATCCTCGAGAACATCATCCCCTCGTCCACCGGCGCCG
CCAAGGCGATGGGCCGGGTGATCCCGGCGCTGAACAACAAGCTCACCGGCATGGCGCTTCGCGTGCCGACCAGCGATGTG
TCGGTGGTCGACCTGACCGTCGAACTCGCCCAGGAGACGAGCTACGAAAAGATCTGCGCGGCGATGAAGGCGGCGAGCCA
GGGCGCCATGAAAGGCGTGCTCGGGTACACGCAGGACAAGGTGGTTTCGACCGACTTCCGCGGCGAGGCCTGCACCGCGG
TGTTCGACGCCGAGGCCGGCATTATGCTCGACTCGACCTTCGTCAAGGTGGTGGCCTGGTACGACAACGAATGGGGCTAC
TCGAGCAAGGTGCTCGAGATGGTGCGCGTGATGGGAGCGTCGCGGTGA

Upstream 100 bases:

>100_bases
GCCTGTTCCCGAGTCTCGCTGATCTTGCGCAGCATGTACTCGCCGGCCGGTCCGGCGCACCTTGCGTTTCGCTCACTTCA
ACCCAACCCACTATCTCATC

Downstream 100 bases:

>100_bases
ACGTGTTGCGCTTCGCCGACCTCGTCGCCCAGGGCCGCGTGTGCGGCCAGCGCGTCTTCATCCGCGCCGACCTCAACGTG
CCGCAGGACGATGCGGGGAA

Product: glyceraldehyde-3-phosphate dehydrogenase A (GAPDH-A)

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTIRIGINGFGRIGRMVFRAAVQDFKNDIEVVAINDLLEPDYLAYMLRYDSVHGRFKGEVVVDGGTLVVNGRKIRLTAVK
DPAALAWGDVGVDVVVESTGLFLTHDTCQKHLDAGARKVIQSAPSKDDTPMFVYGVNHTQYAGEKIVSNASCTTNCLAPV
AKVLNDSFGIKRGMMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAMGRVIPALNNKLTGMALRVPTSDV
SVVDLTVELAQETSYEKICAAMKAASQGAMKGVLGYTQDKVVSTDFRGEACTAVFDAEAGIMLDSTFVKVVAWYDNEWGY
SSKVLEMVRVMGASR

Sequences:

>Translated_335_residues
MTIRIGINGFGRIGRMVFRAAVQDFKNDIEVVAINDLLEPDYLAYMLRYDSVHGRFKGEVVVDGGTLVVNGRKIRLTAVK
DPAALAWGDVGVDVVVESTGLFLTHDTCQKHLDAGARKVIQSAPSKDDTPMFVYGVNHTQYAGEKIVSNASCTTNCLAPV
AKVLNDSFGIKRGMMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAMGRVIPALNNKLTGMALRVPTSDV
SVVDLTVELAQETSYEKICAAMKAASQGAMKGVLGYTQDKVVSTDFRGEACTAVFDAEAGIMLDSTFVKVVAWYDNEWGY
SSKVLEMVRVMGASR
>Mature_334_residues
TIRIGINGFGRIGRMVFRAAVQDFKNDIEVVAINDLLEPDYLAYMLRYDSVHGRFKGEVVVDGGTLVVNGRKIRLTAVKD
PAALAWGDVGVDVVVESTGLFLTHDTCQKHLDAGARKVIQSAPSKDDTPMFVYGVNHTQYAGEKIVSNASCTTNCLAPVA
KVLNDSFGIKRGMMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAMGRVIPALNNKLTGMALRVPTSDVS
VVDLTVELAQETSYEKICAAMKAASQGAMKGVLGYTQDKVVSTDFRGEACTAVFDAEAGIMLDSTFVKVVAWYDNEWGYS
SKVLEMVRVMGASR

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=56.1194029850746, Blast_Score=390, Evalue=1e-109,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=56.0240963855422, Blast_Score=382, Evalue=1e-106,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=69.8170731707317, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=38.2089552238806, Blast_Score=247, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=59.1591591591592, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=58.5585585585586, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=58.7349397590361, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=58.7349397590361, Blast_Score=389, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=62.0060790273556, Blast_Score=423, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=59.8784194528875, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=60.1823708206687, Blast_Score=412, Evalue=1e-116,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=59.0909090909091, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=59.0909090909091, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=58.7878787878788, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=58.7878787878788, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=59.2024539877301, Blast_Score=384, Evalue=1e-107,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36027; Mature: 35896

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRIGINGFGRIGRMVFRAAVQDFKNDIEVVAINDLLEPDYLAYMLRYDSVHGRFKGEV
CEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECEE
VVDGGTLVVNGRKIRLTAVKDPAALAWGDVGVDVVVESTGLFLTHDTCQKHLDAGARKVI
EEECCEEEECCEEEEEEEECCCCCEEECCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHH
QSAPSKDDTPMFVYGVNHTQYAGEKIVSNASCTTNCLAPVAKVLNDSFGIKRGMMTTVHA
HCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHEEHH
ATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAMGRVIPALNNKLTGMALRVPTSDV
HHHCHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCC
SVVDLTVELAQETSYEKICAAMKAASQGAMKGVLGYTQDKVVSTDFRGEACTAVFDAEAG
EEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCC
IMLDSTFVKVVAWYDNEWGYSSKVLEMVRVMGASR
EEEECCEEEEEEEECCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIRIGINGFGRIGRMVFRAAVQDFKNDIEVVAINDLLEPDYLAYMLRYDSVHGRFKGEV
EEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECEE
VVDGGTLVVNGRKIRLTAVKDPAALAWGDVGVDVVVESTGLFLTHDTCQKHLDAGARKVI
EEECCEEEECCEEEEEEEECCCCCEEECCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHH
QSAPSKDDTPMFVYGVNHTQYAGEKIVSNASCTTNCLAPVAKVLNDSFGIKRGMMTTVHA
HCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHEEHH
ATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAMGRVIPALNNKLTGMALRVPTSDV
HHHCHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCC
SVVDLTVELAQETSYEKICAAMKAASQGAMKGVLGYTQDKVVSTDFRGEACTAVFDAEAG
EEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECCCC
IMLDSTFVKVVAWYDNEWGYSSKVLEMVRVMGASR
EEEECCEEEEEEEECCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852; 8366033 [H]