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The map label for this gene is cbbF2

Identifier: 94310453

GI number: 94310453

Start: 1632041

End: 1633138

Strand: Direct

Name: cbbF2

Synonym: Rmet_1511

Alternate gene names: 94310453

Gene position: 1632041-1633138 (Clockwise)

Preceding gene: 94310452

Following gene: 94310454

Centisome position: 41.55

GC content: 66.85

Gene sequence:

>1098_bases
ATGCCACTGTCCCACCGCCAGACCCTGACCCGCTACCTGATCGAGGAACGACGCCGCTTCCCCGAGGCCAGCGGCGAACT
CAACGCGCTGATCCTCGATGTGGCGCTGGCATGCAAGGCGCTGGCCCGCGTCGTGTCGTTCGGAGAACTCGGCGACGCGT
TGAGCGACGGTTCCGCTGCGCCCACGGGGGGGGGCATCAACGTGCAGGGCGAGGTGCAGAAACCGCTGGACGTGCAGTCC
AACGAGATGTTCATCCGCATGAACGAGTGGAACGGGCAACTCGCCGGCATGGCCAGCGAGGAGATGGAGGAGCCGTACCT
GATCCCGAGCTCTTACCCGCGCGGCAAGTACCTGCTCGTGTTCGACCCACTGGACGGCAGCAGCAACATCGACGTCAACG
TCTCCATCGGCAGCATCTTCTCGATCCTGCGCGCCCCGGCCGACGTGGTAGCCAGCGGCCGCGACGTGACCGAAGCGGAC
TTCCTGCAGCCCGGCGCCGCACAGGTCGCCGCCGGCTACACGATCTACGGGCCGACGACGCAACTGGTGCTGACCGTCGG
CAATGGTGTCGCGGCCTTCACGCTGGACCCCAACCTCGGCGAGTTCTTGCTGACGCGCAGCGACATCCGCGTACCCGAGC
AGACGCAGGAGTTCGCAATCAACTCCAGCAACAGCCGGTTCTGGGAGCCGCCGGTCAAGCGCTACGTCGACGAATGCCTG
GCCGGCAAGACCGGGCCGCGCGGCAAGGACTTCAACATGCGCTGGGTCGCGAGTATGGTCGCCGAGGCGCATCGCATCCT
CATGCGCGGCGGTGTCTTCATGTACCCGCGCGACACCAAGGATCCCGCCAAGCCCGGTCGTCTGCGGCTGCTGTACGAGG
CGAATCCGGTCGCAATGCTGATGGAACAGGCCGGCGGCCGCGCCAGCACGGGGCGCGAGCCGATCCTGGGGGTCAGTCCG
ACGGCGCTGCATCAGCGCATCGGCTTGATCTTCGGCAGCAAGGATGAAGTCGAGCGCATCGAGCGCTATCACCAGGAGCC
GGCGTCCAACGAGGCCGCCGCACCGCTGTTCGCCGAACGCAGCCTGTTCCGCGACTGA

Upstream 100 bases:

>100_bases
TCGACCAGGTCGCGCTCACGACTCTTGCCGCGGCGGACATCCGGGTCAGCCGGGTGTTCGCCGCGGCAACCTGACACTGA
ACCACTCCGAGGACTCACCC

Downstream 100 bases:

>100_bases
ACCGAACACGAGCCACCCTGCGAGTCCACACCATGTCAGAAAAACACCCCATCATCGCCATCACGGGCAGTTCCGGCGCC
GGCACGAGCTCGGTGACGCG

Product: fructose-1,6-bisphosphatase I

Products: NA

Alternate protein names: FBPase class 1 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MPLSHRQTLTRYLIEERRRFPEASGELNALILDVALACKALARVVSFGELGDALSDGSAAPTGGGINVQGEVQKPLDVQS
NEMFIRMNEWNGQLAGMASEEMEEPYLIPSSYPRGKYLLVFDPLDGSSNIDVNVSIGSIFSILRAPADVVASGRDVTEAD
FLQPGAAQVAAGYTIYGPTTQLVLTVGNGVAAFTLDPNLGEFLLTRSDIRVPEQTQEFAINSSNSRFWEPPVKRYVDECL
AGKTGPRGKDFNMRWVASMVAEAHRILMRGGVFMYPRDTKDPAKPGRLRLLYEANPVAMLMEQAGGRASTGREPILGVSP
TALHQRIGLIFGSKDEVERIERYHQEPASNEAAAPLFAERSLFRD

Sequences:

>Translated_365_residues
MPLSHRQTLTRYLIEERRRFPEASGELNALILDVALACKALARVVSFGELGDALSDGSAAPTGGGINVQGEVQKPLDVQS
NEMFIRMNEWNGQLAGMASEEMEEPYLIPSSYPRGKYLLVFDPLDGSSNIDVNVSIGSIFSILRAPADVVASGRDVTEAD
FLQPGAAQVAAGYTIYGPTTQLVLTVGNGVAAFTLDPNLGEFLLTRSDIRVPEQTQEFAINSSNSRFWEPPVKRYVDECL
AGKTGPRGKDFNMRWVASMVAEAHRILMRGGVFMYPRDTKDPAKPGRLRLLYEANPVAMLMEQAGGRASTGREPILGVSP
TALHQRIGLIFGSKDEVERIERYHQEPASNEAAAPLFAERSLFRD
>Mature_364_residues
PLSHRQTLTRYLIEERRRFPEASGELNALILDVALACKALARVVSFGELGDALSDGSAAPTGGGINVQGEVQKPLDVQSN
EMFIRMNEWNGQLAGMASEEMEEPYLIPSSYPRGKYLLVFDPLDGSSNIDVNVSIGSIFSILRAPADVVASGRDVTEADF
LQPGAAQVAAGYTIYGPTTQLVLTVGNGVAAFTLDPNLGEFLLTRSDIRVPEQTQEFAINSSNSRFWEPPVKRYVDECLA
GKTGPRGKDFNMRWVASMVAEAHRILMRGGVFMYPRDTKDPAKPGRLRLLYEANPVAMLMEQAGGRASTGREPILGVSPT
ALHQRIGLIFGSKDEVERIERYHQEPASNEAAAPLFAERSLFRD

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=333, Percent_Identity=40.2402402402402, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI189083692, Length=345, Percent_Identity=41.1594202898551, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI16579888, Length=345, Percent_Identity=41.1594202898551, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1790679, Length=340, Percent_Identity=43.2352941176471, Blast_Score=268, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17508131, Length=336, Percent_Identity=42.2619047619048, Blast_Score=254, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6323409, Length=334, Percent_Identity=38.9221556886228, Blast_Score=236, Evalue=3e-63,
Organism=Drosophila melanogaster, GI45550998, Length=341, Percent_Identity=44.574780058651, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI19921562, Length=341, Percent_Identity=44.574780058651, Blast_Score=248, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16A2_RALME (Q1LN82)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_583663.1
- ProteinModelPortal:   Q1LN82
- SMR:   Q1LN82
- STRING:   Q1LN82
- GeneID:   4038314
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_1511
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   PIRAYID
- PhylomeDB:   Q1LN82
- ProtClustDB:   CLSK923881
- BioCyc:   RMET266264:RMET_1511-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 39934; Mature: 39803

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00124 FBPASE

Important sites: BINDING 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSHRQTLTRYLIEERRRFPEASGELNALILDVALACKALARVVSFGELGDALSDGSAA
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PTGGGINVQGEVQKPLDVQSNEMFIRMNEWNGQLAGMASEEMEEPYLIPSSYPRGKYLLV
CCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHCCCCEECCCCCCCCCEEEE
FDPLDGSSNIDVNVSIGSIFSILRAPADVVASGRDVTEADFLQPGAAQVAAGYTIYGPTT
EECCCCCCCEEEEEEHHHHHHHHHCCHHHHHCCCCCCHHHHCCCCHHHHHCCEEEECCCE
QLVLTVGNGVAAFTLDPNLGEFLLTRSDIRVPEQTQEFAINSSNSRFWEPPVKRYVDECL
EEEEEECCCEEEEEECCCCCHHHEECCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHH
AGKTGPRGKDFNMRWVASMVAEAHRILMRGGVFMYPRDTKDPAKPGRLRLLYEANPVAML
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCHHHHH
MEQAGGRASTGREPILGVSPTALHQRIGLIFGSKDEVERIERYHQEPASNEAAAPLFAER
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCCCCHHHHH
SLFRD
HHCCC
>Mature Secondary Structure 
PLSHRQTLTRYLIEERRRFPEASGELNALILDVALACKALARVVSFGELGDALSDGSAA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PTGGGINVQGEVQKPLDVQSNEMFIRMNEWNGQLAGMASEEMEEPYLIPSSYPRGKYLLV
CCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHCCCCEECCCCCCCCCEEEE
FDPLDGSSNIDVNVSIGSIFSILRAPADVVASGRDVTEADFLQPGAAQVAAGYTIYGPTT
EECCCCCCCEEEEEEHHHHHHHHHCCHHHHHCCCCCCHHHHCCCCHHHHHCCEEEECCCE
QLVLTVGNGVAAFTLDPNLGEFLLTRSDIRVPEQTQEFAINSSNSRFWEPPVKRYVDECL
EEEEEECCCEEEEEECCCCCHHHEECCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHH
AGKTGPRGKDFNMRWVASMVAEAHRILMRGGVFMYPRDTKDPAKPGRLRLLYEANPVAML
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCHHHHH
MEQAGGRASTGREPILGVSPTALHQRIGLIFGSKDEVERIERYHQEPASNEAAAPLFAER
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCCCCHHHHH
SLFRD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA