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The map label for this gene is hexR [C]

Identifier: 94310347

GI number: 94310347

Start: 1516970

End: 1517983

Strand: Direct

Name: hexR [C]

Synonym: Rmet_1405

Alternate gene names: 94310347

Gene position: 1516970-1517983 (Clockwise)

Preceding gene: 94310345

Following gene: 94310348

Centisome position: 38.62

GC content: 65.48

Gene sequence:

>1014_bases
ATGGTTGCACCGGGAAAGTGCTTTTTCATCAAAGCGCGATGCCGGTCCTGGTGCGCCAATCATTGTTTCGCGCTGATTCG
CGCGGTTTTGAATGGATCCTGTAGTCCCGAGATGCCAGACGGCCTGCTAATTTCCGAGCGTATTGCACGCGCCTTGCCAA
CGTTGACGCCCGCGCACCAGCGCATGGCGCAGTACGTGCTGGAGAACCCGTTCCGTGCCGCCACGATGCGGATCGACGAG
TTCGCCACGGCCGTGGACGTATCGGTGGCCACGGCCAACCGCTTTGCGCGCGCGCTGGGATTCGAAGGCTATCCGCAGTT
CCGCACCGAACTCGTACGCGGCTTCGAGGCCACGCTGGCCCCGGTGGAGCGATTGCGCGACGAACTGGCGCGGCCCACCA
CGGCGGCGGAGGTGTTCGCGGCCTCGCTCGAGGACGGCATCCGTAACCTGGAAGCCACGCGTCGCGCGCTGGACCCCGAA
GCCTGCGAGCGTGCGGTGTCGGCGATCCTGGAGGCGGAGCGTGTCTACGTGATGGGTTTTGGCGCCAGCGGATTCCTGGC
CGGGCTGCTGCAGCACGGTCTGGAGATGCATTGCCGCATGGTCACGTCGGTGTCCAATTCGGGTGGCGCATCCCATGCGG
GACGGCAACTGTTCAAGTTGCAACCGCAGGATCTGGTCATCGCCATCGCGTTTCCACGCTACGTGACTGACACGATCATG
CTGGCCCAGCGCGTCAAGGAGCACGGCGGCCGATTGATGGCGCTTACCGATGGCCCGGCATCGCCGCTGGCACCGCTGGC
TGACTACACGCTTTACGCCAATACCGGATACCGGTTCTCCGCCAATTCCGATGCCACGGTTCTGGCGCTGATCGAGGCGC
TGTGCGGCGCCGTGGCGCACCGGTCCGCGCGGTCGGTCAAGGCGGCCGCCGAAATGACCGAATTCCTGCTGCCCTGGCTC
CACGGCGCGCCCGACGCGCGTGGTGGCCGGATTGCCCCGAAATCTCCCGACTGA

Upstream 100 bases:

>100_bases
GCCGCTGGCTATGTTCGGCCGCTTGTTCTGAGGGATTACCCCTAATCGGCCACTTTTCACTCTCCTGGTACAGCAATTGC
GTGTAAATTTATTTACATAG

Downstream 100 bases:

>100_bases
TCCCCGACCGAAGTAGAAGGACCCCATGCCTCAAGCTGTTATCGCCATCCACGGTGGCGCGGGCACGATCACCCGTGCCG
CGATGAATGCAGAGCGCGAA

Product: RpiR/GlvR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVAPGKCFFIKARCRSWCANHCFALIRAVLNGSCSPEMPDGLLISERIARALPTLTPAHQRMAQYVLENPFRAATMRIDE
FATAVDVSVATANRFARALGFEGYPQFRTELVRGFEATLAPVERLRDELARPTTAAEVFAASLEDGIRNLEATRRALDPE
ACERAVSAILEAERVYVMGFGASGFLAGLLQHGLEMHCRMVTSVSNSGGASHAGRQLFKLQPQDLVIAIAFPRYVTDTIM
LAQRVKEHGGRLMALTDGPASPLAPLADYTLYANTGYRFSANSDATVLALIEALCGAVAHRSARSVKAAAEMTEFLLPWL
HGAPDARGGRIAPKSPD

Sequences:

>Translated_337_residues
MVAPGKCFFIKARCRSWCANHCFALIRAVLNGSCSPEMPDGLLISERIARALPTLTPAHQRMAQYVLENPFRAATMRIDE
FATAVDVSVATANRFARALGFEGYPQFRTELVRGFEATLAPVERLRDELARPTTAAEVFAASLEDGIRNLEATRRALDPE
ACERAVSAILEAERVYVMGFGASGFLAGLLQHGLEMHCRMVTSVSNSGGASHAGRQLFKLQPQDLVIAIAFPRYVTDTIM
LAQRVKEHGGRLMALTDGPASPLAPLADYTLYANTGYRFSANSDATVLALIEALCGAVAHRSARSVKAAAEMTEFLLPWL
HGAPDARGGRIAPKSPD
>Mature_337_residues
MVAPGKCFFIKARCRSWCANHCFALIRAVLNGSCSPEMPDGLLISERIARALPTLTPAHQRMAQYVLENPFRAATMRIDE
FATAVDVSVATANRFARALGFEGYPQFRTELVRGFEATLAPVERLRDELARPTTAAEVFAASLEDGIRNLEATRRALDPE
ACERAVSAILEAERVYVMGFGASGFLAGLLQHGLEMHCRMVTSVSNSGGASHAGRQLFKLQPQDLVIAIAFPRYVTDTIM
LAQRVKEHGGRLMALTDGPASPLAPLADYTLYANTGYRFSANSDATVLALIEALCGAVAHRSARSVKAAAEMTEFLLPWL
HGAPDARGGRIAPKSPD

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=220, Percent_Identity=24.5454545454545, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 36477; Mature: 36477

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPGKCFFIKARCRSWCANHCFALIRAVLNGSCSPEMPDGLLISERIARALPTLTPAHQ
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHH
RMAQYVLENPFRAATMRIDEFATAVDVSVATANRFARALGFEGYPQFRTELVRGFEATLA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
PVERLRDELARPTTAAEVFAASLEDGIRNLEATRRALDPEACERAVSAILEAERVYVMGF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEEE
GASGFLAGLLQHGLEMHCRMVTSVSNSGGASHAGRQLFKLQPQDLVIAIAFPRYVTDTIM
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHH
LAQRVKEHGGRLMALTDGPASPLAPLADYTLYANTGYRFSANSDATVLALIEALCGAVAH
HHHHHHHHCCEEEEEECCCCCCCCHHHCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHH
RSARSVKAAAEMTEFLLPWLHGAPDARGGRIAPKSPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVAPGKCFFIKARCRSWCANHCFALIRAVLNGSCSPEMPDGLLISERIARALPTLTPAHQ
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHH
RMAQYVLENPFRAATMRIDEFATAVDVSVATANRFARALGFEGYPQFRTELVRGFEATLA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
PVERLRDELARPTTAAEVFAASLEDGIRNLEATRRALDPEACERAVSAILEAERVYVMGF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEEE
GASGFLAGLLQHGLEMHCRMVTSVSNSGGASHAGRQLFKLQPQDLVIAIAFPRYVTDTIM
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHH
LAQRVKEHGGRLMALTDGPASPLAPLADYTLYANTGYRFSANSDATVLALIEALCGAVAH
HHHHHHHHCCEEEEEECCCCCCCCHHHCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHH
RSARSVKAAAEMTEFLLPWLHGAPDARGGRIAPKSPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]