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The map label for this gene is yheS [H]

Identifier: 94310346

GI number: 94310346

Start: 1514869

End: 1516791

Strand: Reverse

Name: yheS [H]

Synonym: Rmet_1404

Alternate gene names: 94310346

Gene position: 1516791-1514869 (Counterclockwise)

Preceding gene: 94310361

Following gene: 94310344

Centisome position: 38.61

GC content: 65.99

Gene sequence:

>1923_bases
GTGATCCGAATCGACCAGCTTGTCCTCCAGCGCGGCACCAAAGTGCTGTTCGACCACACCAGCGTGACGCTCAATCCGGG
CGAGCGCGTCGGCCTTGTCGGCGCCAACGGCAGTGGCAAGTCCACACTGTTCTCCATGCTGCGCGGCGAGTTGCACGCCG
ACGGCGGCGACGTCTTCCTGCCCGCCCAGTGGCGCATTGCGCATGTGGCGCAGGAGACGCCCGCGGTAGCCCGCTCCGCC
GTGGACTATGTGGTCGATGGCGATACCCGCCTGCGCGAGATCGAGGCTCGGATAGCCGCCGCCCAAGCCAGCGGCGATGG
CTCGGCCGAAGGCGAAGCCCATGCAGCCTATGCCGACGCCGACGGCTACACCGCCGCCGCGCGCGCCGAGGCGCTGTTGC
TGGGCCTGGGCTTCACGCTGCCGCAGGTGTCGCAGCCCGTGGCATCGTTCTCGGGCGGCTGGCGGATGCGCTTGAACCTG
GCGCAGGCGCTGATGTGTCCGTCGGACCTGCTGCTGCTTGACGAACCGACCAACCACCTGGACCTCGACGCCATCGTTTG
GCTCGAAGACTGGCTTGCGCGCTACCCAGGCACGCTGGTGATGATCTCGCACGATCGCGAATTCCTCGACGCGATCTGCA
ACGTCACGGTGCATATCGAGAACCAGCAACTGAAGCGTTACGGCGGCAACTACACGCAGTTCGAAACGATGCGGCTGCAG
CAGATGGCGCAGCAGCAGTCGGCCTACGCGCGCCAGCAGAAGGAAATCGCGCACCTGGAGTCGTTCATCAACCGCTTCAA
GGCCAAGGCCACCAAGGCACGCCAGGCGCAAAGCCGGGTGAAGGCGCTGGAAAAGATGGAGCGGCTGGCGCCGGTGCACG
TGGCAGCGGGCTTCGCTTTCGAATTCCGTGAGCCCGATTCGGCGCCGAACCCGATGATGGTGCTGGAAGGTGTGGACTGC
GGCTATGCCGAGGCCGACCCGCCCGTCACGATCCTGCACAACCTTGCACTGTCGATCCAGAACGGCCAGCGCATCGGCCT
GCTGGGCGCGAACGGCCAGGGCAAGTCGACGCTGGTGAAGACGCTGGCCGGCACGCAGGCGCCGCTGAACGGCACCGTCC
GGCTCGGCAAGGGACTCGTGATCGGCTACTTCGCCCAGCACCAGCTGGAAACGCTGCGCGACCACGATTCGCCGCTCCAG
CATCTGGCGCGGCTGGCGCCGGATGTGCGAGAGCAGGAACTGCGCGACTTCCTGGGCAGCTTCAATTTCCGCGGTGACAT
GGCGACGTCACCGATCGAACCGTTCTCGGGCGGCGAGAAGGCCCGGCTGGCGCTGTCCCTGATCGTCTGGCAAAAGCCGA
ACCTGCTGCTGCTAGATGAACCGACCAACCACCTGGACCTCGACACCCGCGAAGCGCTGACGATGGCGCTGGCCCAGTTC
GAAGGCACGCTGATCCTGGTCTCGCACGACCGACATCTGCTGCGCGCCACCTCGGACCAGTTCATGCTCGTGGCCGAGGG
CACGATCCGCCCGTTCGATGGCGATCTGGACGACTACCGCGACTGGCTGCTGCAACAGGCGGCCGCCAAGCGCAACGCGG
CCACGGCCGCGCACGCCGCCGAAGCCGCGCCCGTGGTCAACCGGAAGGACCAGCGCCGCGCAGAAGCCGACGAGCGCCAG
CGCCTGTCGGTACTGCGCAAGCCGCTGACGAAGGAACTGGAAAAGGTGGAAAAGCGGATGTCGGTGCTACAAGCCGACAA
GACCACGATCGACACGTTCATGGCCGACGCGTCGAGTTACGACGACGCCAACAAGACGAAGCTGAAGGACATGCTCAAGC
GCCAGGGCGAAGTCACCGGCGAACTCGAGCAACTGGAGGAACGCTGGCTCGAACTGCAGGAGCAGATCGAGCAGATCGCC
TGA

Upstream 100 bases:

>100_bases
GCGGCCGAACATAGCCAGCGGCGACAGTCTTTGGATGCCGGCGCGATACAATGCCGGCCTGCCGAAAAACCGTTTCCAGC
TTTAGCCTCCCGTCTCCTCC

Downstream 100 bases:

>100_bases
GGCATCTCAATCGACCTGAAGCTTGTGCCCCTCTACCACACGCGGGAGGGGACAAGCTCGGGCACGAGGGACAAGAGGGC
CAAGAACCACGCCGCTCAGC

Product: putative fused ABC transporter ATP-binding proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFSMLRGELHADGGDVFLPAQWRIAHVAQETPAVARSA
VDYVVDGDTRLREIEARIAAAQASGDGSAEGEAHAAYADADGYTAAARAEALLLGLGFTLPQVSQPVASFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLKRYGGNYTQFETMRLQ
QMAQQQSAYARQQKEIAHLESFINRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAFEFREPDSAPNPMMVLEGVDC
GYAEADPPVTILHNLALSIQNGQRIGLLGANGQGKSTLVKTLAGTQAPLNGTVRLGKGLVIGYFAQHQLETLRDHDSPLQ
HLARLAPDVREQELRDFLGSFNFRGDMATSPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
EGTLILVSHDRHLLRATSDQFMLVAEGTIRPFDGDLDDYRDWLLQQAAAKRNAATAAHAAEAAPVVNRKDQRRAEADERQ
RLSVLRKPLTKELEKVEKRMSVLQADKTTIDTFMADASSYDDANKTKLKDMLKRQGEVTGELEQLEERWLELQEQIEQIA

Sequences:

>Translated_640_residues
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFSMLRGELHADGGDVFLPAQWRIAHVAQETPAVARSA
VDYVVDGDTRLREIEARIAAAQASGDGSAEGEAHAAYADADGYTAAARAEALLLGLGFTLPQVSQPVASFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLKRYGGNYTQFETMRLQ
QMAQQQSAYARQQKEIAHLESFINRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAFEFREPDSAPNPMMVLEGVDC
GYAEADPPVTILHNLALSIQNGQRIGLLGANGQGKSTLVKTLAGTQAPLNGTVRLGKGLVIGYFAQHQLETLRDHDSPLQ
HLARLAPDVREQELRDFLGSFNFRGDMATSPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
EGTLILVSHDRHLLRATSDQFMLVAEGTIRPFDGDLDDYRDWLLQQAAAKRNAATAAHAAEAAPVVNRKDQRRAEADERQ
RLSVLRKPLTKELEKVEKRMSVLQADKTTIDTFMADASSYDDANKTKLKDMLKRQGEVTGELEQLEERWLELQEQIEQIA
>Mature_640_residues
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFSMLRGELHADGGDVFLPAQWRIAHVAQETPAVARSA
VDYVVDGDTRLREIEARIAAAQASGDGSAEGEAHAAYADADGYTAAARAEALLLGLGFTLPQVSQPVASFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLKRYGGNYTQFETMRLQ
QMAQQQSAYARQQKEIAHLESFINRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAFEFREPDSAPNPMMVLEGVDC
GYAEADPPVTILHNLALSIQNGQRIGLLGANGQGKSTLVKTLAGTQAPLNGTVRLGKGLVIGYFAQHQLETLRDHDSPLQ
HLARLAPDVREQELRDFLGSFNFRGDMATSPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
EGTLILVSHDRHLLRATSDQFMLVAEGTIRPFDGDLDDYRDWLLQQAAAKRNAATAAHAAEAAPVVNRKDQRRAEADERQ
RLSVLRKPLTKELEKVEKRMSVLQADKTTIDTFMADASSYDDANKTKLKDMLKRQGEVTGELEQLEERWLELQEQIEQIA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=39.7388059701493, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI10947137, Length=532, Percent_Identity=36.8421052631579, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI27881506, Length=532, Percent_Identity=36.8421052631579, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI10947135, Length=545, Percent_Identity=33.5779816513761, Blast_Score=267, Evalue=3e-71,
Organism=Homo sapiens, GI69354671, Length=545, Percent_Identity=33.5779816513761, Blast_Score=266, Evalue=4e-71,
Organism=Escherichia coli, GI1789751, Length=639, Percent_Identity=52.5821596244132, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=36.1742424242424, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1787182, Length=627, Percent_Identity=29.6650717703349, Blast_Score=222, Evalue=7e-59,
Organism=Escherichia coli, GI2367384, Length=526, Percent_Identity=30.4182509505703, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI1788165, Length=199, Percent_Identity=30.6532663316583, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790190, Length=524, Percent_Identity=21.3740458015267, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787758, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788225, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=537, Percent_Identity=36.8715083798883, Blast_Score=338, Evalue=7e-93,
Organism=Caenorhabditis elegans, GI17555318, Length=540, Percent_Identity=35.3703703703704, Blast_Score=329, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17559834, Length=554, Percent_Identity=33.3935018050542, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17569145, Length=324, Percent_Identity=26.8518518518519, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=557, Percent_Identity=35.3680430879713, Blast_Score=330, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6320874, Length=531, Percent_Identity=33.3333333333333, Blast_Score=289, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6325030, Length=389, Percent_Identity=29.8200514138817, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324314, Length=395, Percent_Identity=27.8481012658228, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=395, Percent_Identity=28.6075949367089, Blast_Score=143, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24666836, Length=536, Percent_Identity=38.8059701492537, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24642252, Length=537, Percent_Identity=36.6852886405959, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI18859989, Length=537, Percent_Identity=36.6852886405959, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24641342, Length=557, Percent_Identity=31.9569120287253, Blast_Score=300, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70818; Mature: 70818

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFSMLRGELHADGGDVFL
CCCHHHHHHHCCCEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
PAQWRIAHVAQETPAVARSAVDYVVDGDTRLREIEARIAAAQASGDGSAEGEAHAAYADA
CCCHHHHHHHHHCHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
DGYTAAARAEALLLGLGFTLPQVSQPVASFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLKRYGGNYTQFETMRLQ
CCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCEEEEECCHHHHHHCCCCCHHHHHHHH
QMAQQQSAYARQQKEIAHLESFINRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEE
EFREPDSAPNPMMVLEGVDCGYAEADPPVTILHNLALSIQNGQRIGLLGANGQGKSTLVK
EECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCCHHHHHH
TLAGTQAPLNGTVRLGKGLVIGYFAQHQLETLRDHDSPLQHLARLAPDVREQELRDFLGS
HHHCCCCCCCCEEEECCCEEEEHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHC
FNFRGDMATSPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
CCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHH
EGTLILVSHDRHLLRATSDQFMLVAEGTIRPFDGDLDDYRDWLLQQAAAKRNAATAAHAA
CCEEEEEECCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EAAPVVNRKDQRRAEADERQRLSVLRKPLTKELEKVEKRMSVLQADKTTIDTFMADASSY
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
DDANKTKLKDMLKRQGEVTGELEQLEERWLELQEQIEQIA
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFSMLRGELHADGGDVFL
CCCHHHHHHHCCCEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
PAQWRIAHVAQETPAVARSAVDYVVDGDTRLREIEARIAAAQASGDGSAEGEAHAAYADA
CCCHHHHHHHHHCHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
DGYTAAARAEALLLGLGFTLPQVSQPVASFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLKRYGGNYTQFETMRLQ
CCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCEEEEECCHHHHHHCCCCCHHHHHHHH
QMAQQQSAYARQQKEIAHLESFINRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEE
EFREPDSAPNPMMVLEGVDCGYAEADPPVTILHNLALSIQNGQRIGLLGANGQGKSTLVK
EECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCCHHHHHH
TLAGTQAPLNGTVRLGKGLVIGYFAQHQLETLRDHDSPLQHLARLAPDVREQELRDFLGS
HHHCCCCCCCCEEEECCCEEEEHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHC
FNFRGDMATSPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
CCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHH
EGTLILVSHDRHLLRATSDQFMLVAEGTIRPFDGDLDDYRDWLLQQAAAKRNAATAAHAA
CCEEEEEECCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EAAPVVNRKDQRRAEADERQRLSVLRKPLTKELEKVEKRMSVLQADKTTIDTFMADASSY
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
DDANKTKLKDMLKRQGEVTGELEQLEERWLELQEQIEQIA
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]