Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 94310322

GI number: 94310322

Start: 1489378

End: 1490550

Strand: Direct

Name: yesM [H]

Synonym: Rmet_1380

Alternate gene names: 94310322

Gene position: 1489378-1490550 (Clockwise)

Preceding gene: 94310321

Following gene: 94310323

Centisome position: 37.92

GC content: 65.3

Gene sequence:

>1173_bases
ATGCGCCTATCGTGCGCGGGCCCGTCGCGGCTCAATATTCTTTGGCGCGACCTGCTGTTCGTGCTCTGCATGAACACGGT
GATCGCCGTCAGCCTCAACTACGGCTTCCGTACCGCCGGAACGCTGCTCCAGAATTTTGCCTACAGCCAGCTGATCGGTC
TCTCGATCTGGGTGCTGATCGATATCCCCCGCGTCCTGATCTGGTGGAACGATCGTCCGCGTCGATGGCCGTTCATGTGC
CTGGCCGTGGTGGCGGTGCCAATGGGCGTGGTGATGGGTAGCTGGGCGACACGCGAATTGCTGGGGCTGCCGGAGAAGTC
CGCGGCGGAGACCGGCGACATGCTGCGCATGTGCCTGATCGTCGGGATGCTGGCGTCGGCGAGCATGATCTACTTCTACT
GGTCGCGCGAGAAGCTGGCGTACCTGGAGCGGCAGGCCGCGCTCGACGCCTTGCAGCGCGAGGAAGCCGAAAAGCAACTC
GTGCGCGCCCAGTTGATGGCGCTGCAGGCACAGATCGAGCCGCATTTCCTGTTCAACTCGCTGGCCAATCTCGACGGCCT
GATCGCCACCGACCCCCGCGCGGCGCGCCAGTTGCTGCAGCGGCTGATCGGTTTCCTGCGCATGTCGTTGTCCCACACCC
GCGCTGAGCATTGCACGCTGGCGCAGGAGTTCGAGTTGCTGCGCAGCTACCTCGATATCCAGGGTATGCGATTTGGCGCG
CGGCTCGATTACGAGATCGACCTGCCGCCAGCGCTGGCCGAGGCGGAGATTCCGCCGATGCTGGTGCAGCCGCTGGTCGA
GAACGCGGTGACTCACGGTATCGAGCCGTGCATGCGCGGCGGGAAGATCGTGCTGTCCGCGCGCGAGACTGGGGACGGCA
GCCTGCAGGTGGTCATCGCCGACACCGGCGTGGGATTCAGCCAGGGCAATAAGGGCAGCAAGGGCGGTTCCGGGCTTGGC
CTGACCCATGTGCGCGAGCGCCTGGCACGGATCTTCGGCGCAGCGGCCACGATGCAAATGGAAGAGAACACGCCACGTGG
TGTGGTAGTGCGCCTGACGTTGCCGCTCCAGCGCGGTTTCGAACCAATGTCCGTACCGGTTCGCGCCGCTGCGGGCGCCG
CCGATCTGCAACATGCGCCTGCCGGTGTGGCCCCGGCAGTTTCCCGATCCTGA

Upstream 100 bases:

>100_bases
CCCATCGCGGCCCGGCGGTGTTTCCTTGCCCGGTCTTGCGCGATGCTGCAGTGCATCAGAGATTTGCACGCGGTACCTGT
AGCGAGAGGAGGGAGAGAAC

Downstream 100 bases:

>100_bases
TTGCACAGCCTGACAATTCATCCCCATGTCTCCGACGCTGCTGATCGCCGACGACGAACCGTTGCTCGCGCGCGTGCTGG
AATCCGAACTGAAGGCGCTG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRLSCAGPSRLNILWRDLLFVLCMNTVIAVSLNYGFRTAGTLLQNFAYSQLIGLSIWVLIDIPRVLIWWNDRPRRWPFMC
LAVVAVPMGVVMGSWATRELLGLPEKSAAETGDMLRMCLIVGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQL
VRAQLMALQAQIEPHFLFNSLANLDGLIATDPRAARQLLQRLIGFLRMSLSHTRAEHCTLAQEFELLRSYLDIQGMRFGA
RLDYEIDLPPALAEAEIPPMLVQPLVENAVTHGIEPCMRGGKIVLSARETGDGSLQVVIADTGVGFSQGNKGSKGGSGLG
LTHVRERLARIFGAAATMQMEENTPRGVVVRLTLPLQRGFEPMSVPVRAAAGAADLQHAPAGVAPAVSRS

Sequences:

>Translated_390_residues
MRLSCAGPSRLNILWRDLLFVLCMNTVIAVSLNYGFRTAGTLLQNFAYSQLIGLSIWVLIDIPRVLIWWNDRPRRWPFMC
LAVVAVPMGVVMGSWATRELLGLPEKSAAETGDMLRMCLIVGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQL
VRAQLMALQAQIEPHFLFNSLANLDGLIATDPRAARQLLQRLIGFLRMSLSHTRAEHCTLAQEFELLRSYLDIQGMRFGA
RLDYEIDLPPALAEAEIPPMLVQPLVENAVTHGIEPCMRGGKIVLSARETGDGSLQVVIADTGVGFSQGNKGSKGGSGLG
LTHVRERLARIFGAAATMQMEENTPRGVVVRLTLPLQRGFEPMSVPVRAAAGAADLQHAPAGVAPAVSRS
>Mature_390_residues
MRLSCAGPSRLNILWRDLLFVLCMNTVIAVSLNYGFRTAGTLLQNFAYSQLIGLSIWVLIDIPRVLIWWNDRPRRWPFMC
LAVVAVPMGVVMGSWATRELLGLPEKSAAETGDMLRMCLIVGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQL
VRAQLMALQAQIEPHFLFNSLANLDGLIATDPRAARQLLQRLIGFLRMSLSHTRAEHCTLAQEFELLRSYLDIQGMRFGA
RLDYEIDLPPALAEAEIPPMLVQPLVENAVTHGIEPCMRGGKIVLSARETGDGSLQVVIADTGVGFSQGNKGSKGGSGLG
LTHVRERLARIFGAAATMQMEENTPRGVVVRLTLPLQRGFEPMSVPVRAAAGAADLQHAPAGVAPAVSRS

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=182, Percent_Identity=36.8131868131868, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788723, Length=253, Percent_Identity=29.2490118577075, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42880; Mature: 42880

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSCAGPSRLNILWRDLLFVLCMNTVIAVSLNYGFRTAGTLLQNFAYSQLIGLSIWVLI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEE
DIPRVLIWWNDRPRRWPFMCLAVVAVPMGVVMGSWATRELLGLPEKSAAETGDMLRMCLI
ECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHH
VGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQLVRAQLMALQAQIEPHFLFNS
HHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LANLDGLIATDPRAARQLLQRLIGFLRMSLSHTRAEHCTLAQEFELLRSYLDIQGMRFGA
HHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
RLDYEIDLPPALAEAEIPPMLVQPLVENAVTHGIEPCMRGGKIVLSARETGDGSLQVVIA
EECEEECCCCCHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCCCEEEEEE
DTGVGFSQGNKGSKGGSGLGLTHVRERLARIFGAAATMQMEENTPRGVVVRLTLPLQRGF
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEECHHHCC
EPMSVPVRAAAGAADLQHAPAGVAPAVSRS
CCCCCCHHHHCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLSCAGPSRLNILWRDLLFVLCMNTVIAVSLNYGFRTAGTLLQNFAYSQLIGLSIWVLI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEE
DIPRVLIWWNDRPRRWPFMCLAVVAVPMGVVMGSWATRELLGLPEKSAAETGDMLRMCLI
ECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHH
VGMLASASMIYFYWSREKLAYLERQAALDALQREEAEKQLVRAQLMALQAQIEPHFLFNS
HHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LANLDGLIATDPRAARQLLQRLIGFLRMSLSHTRAEHCTLAQEFELLRSYLDIQGMRFGA
HHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
RLDYEIDLPPALAEAEIPPMLVQPLVENAVTHGIEPCMRGGKIVLSARETGDGSLQVVIA
EECEEECCCCCHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCCCEEEEEE
DTGVGFSQGNKGSKGGSGLGLTHVRERLARIFGAAATMQMEENTPRGVVVRLTLPLQRGF
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEECHHHCC
EPMSVPVRAAAGAADLQHAPAGVAPAVSRS
CCCCCCHHHHCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]