BacMap

Definition	Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession	NC_007973
Length	3,928,089

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The map label for this gene is phaB2 [H]

Identifier: 94310275

GI number: 94310275

Start: 1444571

End: 1445317

Strand: Direct

Name: phaB2 [H]

Synonym: Rmet_1333

Alternate gene names: 94310275

Gene position: 1444571-1445317 (Clockwise)

Preceding gene: 335055525

Following gene: 94310276

Centisome position: 36.78

GC content: 63.72

Gene sequence:

>747_bases
ATGAATACGACGCAACGGACGGCGCTCGTGACGGGAGGCAACCGGGGGTTGGGCGCTGCGATCGCCCGTGCCCTGCACGA
TGCCGGCCACCGCGTGATCGTCACGCATACCCCCGGCAACACCACGATTGGCCAGTGGCAGCAAGCGCAAGCGACACAGG
GCTACTCATTTGCCGCCTACGGGGTGGATGTATCGGACTACGAATCAACGCAGGAACTGGCGCGGCGCATCCACGCCGAC
GGTCATCGGATCGACATCCTGGTGAACAACGCCGGCATCACCCGCGATGCAACGCTGCGCAAGCTCGACAAGGCCGGTTG
GGATGCCGTACTGCGCACCAACCTGGACTCCATGTTCAACGTCACCAAGCCGTTCATCGACCCGATGGCCGAGCGCGGCT
GGGGCCGCATCGTCAACATCTCTTCGATCAACGGCAGCAAGGGCCAGTTCGGGCAGACCAATTATTCGGCGGCCAAGGCC
GGGGTACATGGATTCACCAAGGCGCTCGCACAGGAGGTGGCGCGCAAGGGCGTGACGGTCAACACCGTCTCGCCGGGCTA
TCTGGCCACCGAGATGGTGATGGCGGTGCGAGAGGACATGCGCCAGAAGATCATCGATGCGATTCCGGTTGGCCGTCTCG
GCCAGCCGGCCGAGATTGCAGCTCTTGTCGCCTTCATCGCCAGCGAAGCCGCCGCCTTCATGACCGGCAGCAACGTGGCG
ATGAACGGCGGTCAGCACATGTCTTGA

Upstream 100 bases:

>100_bases
GACGCAGCCTCTTTCACGCAGCTTTGCCAGCGCTTGGCGCAGCCCTGGACCGCCCCAAGCGCCGTACCCCAGGGCAAGAC
CAAGAAATGAGGGGACGGCA

Downstream 100 bases:

>100_bases
GCCCACTGCGCGAGCGGCTGACTTCCGACGCGGCAATCCGCAGCTCTTGGAGGAGTTCCATGTATTCACGATTTCTGGTG
CCGCTTGATGGCAGTCCCAC

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNTTQRTALVTGGNRGLGAAIARALHDAGHRVIVTHTPGNTTIGQWQQAQATQGYSFAAYGVDVSDYESTQELARRIHAD
GHRIDILVNNAGITRDATLRKLDKAGWDAVLRTNLDSMFNVTKPFIDPMAERGWGRIVNISSINGSKGQFGQTNYSAAKA
GVHGFTKALAQEVARKGVTVNTVSPGYLATEMVMAVREDMRQKIIDAIPVGRLGQPAEIAALVAFIASEAAAFMTGSNVA
MNGGQHMS

Sequences:

>Translated_248_residues
MNTTQRTALVTGGNRGLGAAIARALHDAGHRVIVTHTPGNTTIGQWQQAQATQGYSFAAYGVDVSDYESTQELARRIHAD
GHRIDILVNNAGITRDATLRKLDKAGWDAVLRTNLDSMFNVTKPFIDPMAERGWGRIVNISSINGSKGQFGQTNYSAAKA
GVHGFTKALAQEVARKGVTVNTVSPGYLATEMVMAVREDMRQKIIDAIPVGRLGQPAEIAALVAFIASEAAAFMTGSNVA
MNGGQHMS
>Mature_248_residues
MNTTQRTALVTGGNRGLGAAIARALHDAGHRVIVTHTPGNTTIGQWQQAQATQGYSFAAYGVDVSDYESTQELARRIHAD
GHRIDILVNNAGITRDATLRKLDKAGWDAVLRTNLDSMFNVTKPFIDPMAERGWGRIVNISSINGSKGQFGQTNYSAAKA
GVHGFTKALAQEVARKGVTVNTVSPGYLATEMVMAVREDMRQKIIDAIPVGRLGQPAEIAALVAFIASEAAAFMTGSNVA
MNGGQHMS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=36.6935483870968, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=34.0163934426229, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.9236947791165, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=31.3492063492063, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4504505, Length=233, Percent_Identity=33.0472103004292, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=31.0526315789474, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=32.7586206896552, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=29.5275590551181, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=29.5833333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=26.7489711934156, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.0588235294118, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=28.3950617283951, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542939, Length=216, Percent_Identity=30.0925925925926, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=28.2258064516129, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7657478, Length=195, Percent_Identity=29.7435897435897, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=29.1005291005291, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=210, Percent_Identity=28.0952380952381, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI150247226, Length=188, Percent_Identity=30.8510638297872, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=181, Percent_Identity=27.0718232044199, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19743808, Length=207, Percent_Identity=30.9178743961353, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157739938, Length=187, Percent_Identity=25.1336898395722, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=31.3829787234043, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.7435897435897, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=43.8247011952191, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=33.201581027668, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=31.1203319502075, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=29.0983606557377, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.7937743190661, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=30.46875, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.4677419354839, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=29.4605809128631, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.1652892561983, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=27.6422764227642, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=30.3867403314917, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=39.344262295082, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=38.1526104417671, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=31.0483870967742, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17568967, Length=232, Percent_Identity=31.8965517241379, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=30.6513409961686, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=27.6422764227642, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=28.957528957529, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=28.0155642023346, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=31.1224489795918, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=31.9371727748691, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.8461538461538, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=30.1204819277108, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=30.2681992337165, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=27.3092369477912, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=28.5171102661597, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.7924528301887, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.6290322580645, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.9701492537313, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=27.1255060728745, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=26.4591439688716, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=26.8939393939394, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=26.2548262548263, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=171, Percent_Identity=29.8245614035088, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.4809160305344, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=25.5813953488372, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.8195488721804, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=22.1374045801527, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=212, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=212, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=25.7692307692308, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=30.1724137931034, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320089, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=211, Percent_Identity=26.0663507109005, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=38.0165289256198, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=35.3174603174603, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=31.5789473684211, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=30.3643724696356, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859837, Length=231, Percent_Identity=34.6320346320346, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=27.9835390946502, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=33.9181286549708, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=28.8537549407115, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=30.5699481865285, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=29.0697674418605, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=154, Percent_Identity=29.2207792207792, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=212, Percent_Identity=31.1320754716981, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=195, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161076933, Length=195, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=29.4685990338164, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26437; Mature: 26437

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTQRTALVTGGNRGLGAAIARALHDAGHRVIVTHTPGNTTIGQWQQAQATQGYSFAAY
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEEE
GVDVSDYESTQELARRIHADGHRIDILVNNAGITRDATLRKLDKAGWDAVLRTNLDSMFN
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHH
VTKPFIDPMAERGWGRIVNISSINGSKGQFGQTNYSAAKAGVHGFTKALAQEVARKGVTV
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
NTVSPGYLATEMVMAVREDMRQKIIDAIPVGRLGQPAEIAALVAFIASEAAAFMTGSNVA
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
MNGGQHMS
ECCCCCCC
>Mature Secondary Structure
MNTTQRTALVTGGNRGLGAAIARALHDAGHRVIVTHTPGNTTIGQWQQAQATQGYSFAAY
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEEE
GVDVSDYESTQELARRIHADGHRIDILVNNAGITRDATLRKLDKAGWDAVLRTNLDSMFN
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHH
VTKPFIDPMAERGWGRIVNISSINGSKGQFGQTNYSAAKAGVHGFTKALAQEVARKGVTV
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
NTVSPGYLATEMVMAVREDMRQKIIDAIPVGRLGQPAEIAALVAFIASEAAAFMTGSNVA
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
MNGGQHMS
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]