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The map label for this gene is hoxK [H]

Identifier: 94310242

GI number: 94310242

Start: 1414328

End: 1415422

Strand: Reverse

Name: hoxK [H]

Synonym: Rmet_1298

Alternate gene names: 94310242

Gene position: 1415422-1414328 (Counterclockwise)

Preceding gene: 94310244

Following gene: 94310241

Centisome position: 36.03

GC content: 65.21

Gene sequence:

>1095_bases
ATGGAAACCTTTTACGAGATCATGCGCCGCAAAGGCATTTCGCGCCGCAGTTTCATGAAGTACTGCTCGCTCACCGCCAC
CTCGCTGGGGCTGGCACCGAGCTTTGTGCCCCAGATCGCCCACGCGATGGAAAACAAGCCGCGCACCCCGGTGCTCTGGC
TGCACGGTCTGGAATGCACCTGCTGCACCGAAGCCTTCATCCGCTCGGCCCACCCGCTGGCCAAGGACGTGGTGCTCTCC
ATGATCAGCCTGGACTACGACGACACCCTGATGGCCGCCGCCGGCCACCAGGCCGAGGCCATCCTCGAAGAGATCATGAC
CAAGTACAAGGGTCAGTACATCCTGGCGGTGGAAGGCAATCCGCCGCTGAACGAAGACGGCATGTTCTGCATCCAGTCGG
GCAAGCCCTTCATCGACAAGCTCAAGCACGTGGCCAAGGACGCCAAGGCCATCATCGCCTGGGGTTCGTGCGCCAGCTGG
GGCTGCGTGCAGGCCGCCAAGCCCAACCCGACCCAGGCCACGCCCATCCACAAGGTCATCACCGACAAGCCCATCATCAA
GGTGCCGGGCTGCCCGCCCATCCCCGAGGTGATGACGGGCGTGATCACCTACATGCTGACCTTCGACCGCATTCCCGAGC
TGGACCGCCAGGGCCGCCCGAAGATGTTCTACAGCCAGCGCATCCACGACAAGTGCTACCGCCGCCCTCACTTCGACGCC
GGCCAGTTCGTCGAGGCGTGGGACGACGACTCCGCGCGCAAGGGCTACTGCCTCTACAAGGTGGGCTGCAAGGGCCCGAC
CACCTACAACGCCTGCTCCACCGTGCAGTGGAACGAGGGCACGAGCTTCCCCATCAAGGCCGGCCACGGTTGCATCGGCT
GCTCGGAAGACGGCTTCTGGGACAAGGGTTCGTTCTACGACCGCCTCACCGACATCCACGCCTTCGGCATCGAAGCCAAT
GCCGACCAGATCGGTGGCACGGCCGCCGGCGTGGTGGGCGCGGCGGTGGCGGCCCACGCGGCCATCTCGGTGGCCAAGCG
CGTGCGCGACAACAACGCCCGCAAGCCCGACGCATCCACACCCGCCAACCACTGA

Upstream 100 bases:

>100_bases
AAGCCCCGACGCACAGCACTGGTGCAAAAGCGTACATTGTCGGCACTCGCGAACGGTGCTCTGCACCGCGCAACGCGGGG
AACCGAGGAGACAACCCACG

Downstream 100 bases:

>100_bases
CACGACCGAGGAACAAGAACATGGGTGCTTACGAAACTCAAGGCTTCCGCATGGACAACACGGGCCGGCGCATCGTCGTC
GACCCGGTGACCCGCATCGA

Product: HoxK membrane-bound (NiFe) hydrogenase small subunit

Products: NA

Alternate protein names: Hydrogenlyase; Membrane-bound hydrogenase small subunit [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
METFYEIMRRKGISRRSFMKYCSLTATSLGLAPSFVPQIAHAMENKPRTPVLWLHGLECTCCTEAFIRSAHPLAKDVVLS
MISLDYDDTLMAAAGHQAEAILEEIMTKYKGQYILAVEGNPPLNEDGMFCIQSGKPFIDKLKHVAKDAKAIIAWGSCASW
GCVQAAKPNPTQATPIHKVITDKPIIKVPGCPPIPEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFDA
GQFVEAWDDDSARKGYCLYKVGCKGPTTYNACSTVQWNEGTSFPIKAGHGCIGCSEDGFWDKGSFYDRLTDIHAFGIEAN
ADQIGGTAAGVVGAAVAAHAAISVAKRVRDNNARKPDASTPANH

Sequences:

>Translated_364_residues
METFYEIMRRKGISRRSFMKYCSLTATSLGLAPSFVPQIAHAMENKPRTPVLWLHGLECTCCTEAFIRSAHPLAKDVVLS
MISLDYDDTLMAAAGHQAEAILEEIMTKYKGQYILAVEGNPPLNEDGMFCIQSGKPFIDKLKHVAKDAKAIIAWGSCASW
GCVQAAKPNPTQATPIHKVITDKPIIKVPGCPPIPEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFDA
GQFVEAWDDDSARKGYCLYKVGCKGPTTYNACSTVQWNEGTSFPIKAGHGCIGCSEDGFWDKGSFYDRLTDIHAFGIEAN
ADQIGGTAAGVVGAAVAAHAAISVAKRVRDNNARKPDASTPANH
>Mature_364_residues
METFYEIMRRKGISRRSFMKYCSLTATSLGLAPSFVPQIAHAMENKPRTPVLWLHGLECTCCTEAFIRSAHPLAKDVVLS
MISLDYDDTLMAAAGHQAEAILEEIMTKYKGQYILAVEGNPPLNEDGMFCIQSGKPFIDKLKHVAKDAKAIIAWGSCASW
GCVQAAKPNPTQATPIHKVITDKPIIKVPGCPPIPEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFDA
GQFVEAWDDDSARKGYCLYKVGCKGPTTYNACSTVQWNEGTSFPIKAGHGCIGCSEDGFWDKGSFYDRLTDIHAFGIEAN
ADQIGGTAAGVVGAAVAAHAAISVAKRVRDNNARKPDASTPANH

Specific function: This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions [H]

COG id: COG1740

COG function: function code C; Ni,Fe-hydrogenase I small subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family [H]

Homologues:

Organism=Escherichia coli, GI1787206, Length=329, Percent_Identity=74.1641337386018, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1789371, Length=294, Percent_Identity=43.1972789115646, Blast_Score=275, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR001821
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.12.99.6 [H]

Molecular weight: Translated: 39952; Mature: 39952

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METFYEIMRRKGISRRSFMKYCSLTATSLGLAPSFVPQIAHAMENKPRTPVLWLHGLECT
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCHH
CCTEAFIRSAHPLAKDVVLSMISLDYDDTLMAAAGHQAEAILEEIMTKYKGQYILAVEGN
HHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCC
PPLNEDGMFCIQSGKPFIDKLKHVAKDAKAIIAWGSCASWGCVQAAKPNPTQATPIHKVI
CCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
TDKPIIKVPGCPPIPEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFDA
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
GQFVEAWDDDSARKGYCLYKVGCKGPTTYNACSTVQWNEGTSFPIKAGHGCIGCSEDGFW
CCHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEECCCCEEECCCCCCC
DKGSFYDRLTDIHAFGIEANADQIGGTAAGVVGAAVAAHAAISVAKRVRDNNARKPDAST
CCCCHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PANH
CCCC
>Mature Secondary Structure
METFYEIMRRKGISRRSFMKYCSLTATSLGLAPSFVPQIAHAMENKPRTPVLWLHGLECT
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCHH
CCTEAFIRSAHPLAKDVVLSMISLDYDDTLMAAAGHQAEAILEEIMTKYKGQYILAVEGN
HHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCC
PPLNEDGMFCIQSGKPFIDKLKHVAKDAKAIIAWGSCASWGCVQAAKPNPTQATPIHKVI
CCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
TDKPIIKVPGCPPIPEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFDA
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
GQFVEAWDDDSARKGYCLYKVGCKGPTTYNACSTVQWNEGTSFPIKAGHGCIGCSEDGFW
CCHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEECCCCEEECCCCCCC
DKGSFYDRLTDIHAFGIEANADQIGGTAAGVVGAAVAAHAAISVAKRVRDNNARKPDAST
CCCCHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PANH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1383192; 12948488; 2493816 [H]