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The map label for this gene is siaT [H]

Identifier: 94310094

GI number: 94310094

Start: 1259559

End: 1260863

Strand: Direct

Name: siaT [H]

Synonym: Rmet_1149

Alternate gene names: 94310094

Gene position: 1259559-1260863 (Clockwise)

Preceding gene: 94310093

Following gene: 94310095

Centisome position: 32.07

GC content: 65.52

Gene sequence:

>1305_bases
ATGACGCTGATCGCCATCATTCTGTTCGTGGTTTTCATTGGCCTGATGCTGCTGGGCGCGCCAATTGGCGTGTCGCTGGG
GCTGGGCGGTCTGGTCGCCATCGGCCTGTCGAACCTCGATACGCAAATGTTCGGCCTGCTGGCCGTGCCCCAGAACTTCT
ATGCCGGTCTTGCCAAGTACCCGCTGCTGGCCATTCCCATGTTCGTGCTGGTCGGTTCGATCTTCGATCGTTCCGGCGTA
GCGCAACGACTGGTCACGTTCGCCATCGCGATCGTGGGCCGTGGTCCGGGCATGTTGCCGCTGGTGGCCATCCTCGTGGC
GATGTTCCTGGGCGGCATCTCCGGCTCTGGTCCCGCGAACGCGGCCGCGGTAGGGGGCGTGATGATCGCGGCGATGTCGC
GTGCGGGCTATCCGGGCTCCTACAGCGCCGCGGTGGTTGGCGCGGCGGCGGCTACGGACATTCTGATCCCGCCGTCGGTG
GCGTTCATTATCTACAGCGTGCTGGTGCCAGGCGCATCGGTGCCCGCGCTGTTCGCCGCCGGCATGATCCCGGGCATCCT
GGCCGGTGTGGCGTTGATCGTTCCGGCCGTCTGGCTGGCGCGCAAGCACAACATGGGGCATATCGAAGCCGGCTTGCCGC
GCCCGCCGTTCTGGAAGAGCCTGCGCGAGGCCGCATGGGGCCTGGTGGCGCCGTTCCTGATTCTGGGTGGCATGCGCGCG
GGCTGGTTCACGCCGACCGAGGCCGCCGTCGTGGCCGTGGTCTACGGGTTGTTCGTCGGCATGGTGATCTATCGCAGCAT
TGGCGTGCGCGACCTGTTCACGATTTTCCAGGAGGCGGCCGAGACATCGGCGGTGATCCTGCTGGTGGTGGCGCTGGCCG
GCATCTTCGCCTATGCGCTGTCCACGCTCGGCGTAATCGACCCGCTGGCCAATGCCATTGCGCATTCGGGGCTGGGCGAG
TACGGCGTGCTGGCGCTGATCGTGCTGTTGCTGATGACCGTCGGCATGTTCCTGGACGGCATCTCGATCTTCCTGATCTT
CGTGCCGCTGCTGCTCCCGATCGCCACCGCGTTCCACTGGAATCCGGTATGGTTTGGCGTGGTGCTCACGCTCAAGGTGG
CGCTGGGTCAGTTCACCCCGCCACTGGCCGTGAACCTGATGGTGTCGTGCCGCATCGCGCGCGTGCGCATGGAAGAGACC
GTGCCATGGGTGATCTGGATGCTGCTGGCGATGTTCGTCGCCATGCTGATGGTGCTGGCCTATCCGCCGCTGGCCACCTG
GCTGCCCGACTACCTGGGCTATTGA

Upstream 100 bases:

>100_bases
TGCCCGTGCTGTCGATCTCAATAACGCTGCGGGCGCTGGCTCTGGCCCTGCGCAATGTCCGGGCGCTGCGTGCCCTGAAG
AACGATGGGGAGCGCGCGCA

Downstream 100 bases:

>100_bases
TATGAACGAGAAAACGAAAAGAGGAGATTCCCGGATGAAACGCCGTGCCCTGATGCTGTCCGTTGCCGCTTCGATCGCCG
CCGCCGCGCTTGCGCCGGCC

Product: TRAP dicarboxylate transporter- DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTLIAIILFVVFIGLMLLGAPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKYPLLAIPMFVLVGSIFDRSGV
AQRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPANAAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSV
AFIIYSVLVPGASVPALFAAGMIPGILAGVALIVPAVWLARKHNMGHIEAGLPRPPFWKSLREAAWGLVAPFLILGGMRA
GWFTPTEAAVVAVVYGLFVGMVIYRSIGVRDLFTIFQEAAETSAVILLVVALAGIFAYALSTLGVIDPLANAIAHSGLGE
YGVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHWNPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEET
VPWVIWMLLAMFVAMLMVLAYPPLATWLPDYLGY

Sequences:

>Translated_434_residues
MTLIAIILFVVFIGLMLLGAPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKYPLLAIPMFVLVGSIFDRSGV
AQRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPANAAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSV
AFIIYSVLVPGASVPALFAAGMIPGILAGVALIVPAVWLARKHNMGHIEAGLPRPPFWKSLREAAWGLVAPFLILGGMRA
GWFTPTEAAVVAVVYGLFVGMVIYRSIGVRDLFTIFQEAAETSAVILLVVALAGIFAYALSTLGVIDPLANAIAHSGLGE
YGVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHWNPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEET
VPWVIWMLLAMFVAMLMVLAYPPLATWLPDYLGY
>Mature_433_residues
TLIAIILFVVFIGLMLLGAPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKYPLLAIPMFVLVGSIFDRSGVA
QRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPANAAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSVA
FIIYSVLVPGASVPALFAAGMIPGILAGVALIVPAVWLARKHNMGHIEAGLPRPPFWKSLREAAWGLVAPFLILGGMRAG
WFTPTEAAVVAVVYGLFVGMVIYRSIGVRDLFTIFQEAAETSAVILLVVALAGIFAYALSTLGVIDPLANAIAHSGLGEY
GVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHWNPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEETV
PWVIWMLLAMFVAMLMVLAYPPLATWLPDYLGY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=393, Percent_Identity=31.8066157760814, Blast_Score=164, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45460; Mature: 45329

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHCC
>Mature Secondary Structure 
TLIAIILFVVFIGLMLLGAPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKY
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PLLAIPMFVLVGSIFDRSGVAQRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCH
AAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSVAFIIYSVLVPGASVPALFAA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHH
GMIPGILAGVALIVPAVWLARKHNMGHIEAGLPRPPFWKSLREAAWGLVAPFLILGGMRA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GWFTPTEAAVVAVVYGLFVGMVIYRSIGVRDLFTIFQEAAETSAVILLVVALAGIFAYAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLGVIDPLANAIAHSGLGEYGVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHW
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEETVPWVIWMLLAMFVAMLMVLA
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPPLATWLPDYLGY
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]