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The map label for this gene is aroC [H]

Identifier: 94310083

GI number: 94310083

Start: 1245129

End: 1246238

Strand: Direct

Name: aroC [H]

Synonym: Rmet_1138

Alternate gene names: 94310083

Gene position: 1245129-1246238 (Clockwise)

Preceding gene: 94310082

Following gene: 94310084

Centisome position: 31.7

GC content: 65.23

Gene sequence:

>1110_bases
ATGTCTGGCAATACCCTCGGCCTGCTTTTCACAGTTACCACGTTCGGCGAATCGCACGGGCCCGCCATCGGCGCGGTAGT
GGATGGCTGCCCGCCGGGGATGTCGCTGACCGAAGCCGACATCCAGATCGACCTGGACCGCCGCAAGCCCGGCACGTCGC
GCCACGTGACACAGCGCCAGGAAGCGGATCAGGTGGAGATCCTGTCCGGCGTATTCGAAGGTAAGACCACGGGCACGCCG
ATCTGCCTGCTGATCCGCAACACCGACCAGCGCAGCAAGGACTACGGCAACATCGTCGAGACGTTCCGCCCGGGCCATGC
CGACTACACCTACTGGCACAAGTACGGTATCCGTGACTATCGCGGTGGTGGCCGCTCGTCGGCGCGCCTGACCGCACCCG
TGGTGGCCGCCGCGGCAATCGCGAAGAAATGGCTGAATGAGCAGTACGGCACCGAGATTCGTGGCTACATGTCGCAGCTC
GGTGAGGTCGAAGTGCCGTTCACCGACTGGAAACACGTGCCGGAGAACCCGTTCTTCGCGGCGAATGCCGATATCGTTCC
CGAGTTGGAAACCTACATGGATGCGCTGCGCCGCGACGGCGACTCCGTCGGCGCGCGTATCGAAGTGGTGGCCAGCCATG
TGCCGGTGGGTCTGGGCGAGCCGCTGTTCGACAAGCTCGACGCCGATATCGCGCACGCAATGATGGGCATCAACGCGGTC
AAGGGCGTCGAGATCGGCGCTGGCTTCGACAGCGTGTCCCAGCGCGGCACCGTGCATGGCGACGAACTGACGCCGGAGGG
GTTCCGCACGAATAACTCGGGTGGCGTGCTCGGCGGGATTTCCACCGGGCAGGACATCAAGGTATCGCTGGCAATCAAGC
CGACGTCGAGCATCCGTACCGCGCGCGAATCGATCGACAAGGCTGGCAGCCCGGCCAGCGTGGAAACGTTCGGTCGCCAC
GACCCGTGCGTCGGCATCCGCGCCACGCCGATCGCCGAAGCCATGCTTGCGCTGGTGCTGATGGACCACGCATTGCGGCA
TCGCGCCCAATGCGGTGACGTCCGCGTCGACACCCCGCGCATCCCGGCGCAAGCACCGGGCAAATCCTGA

Upstream 100 bases:

>100_bases
CCGCAACGGCAGGCCGGCCCGAGGCGGCTTTCGGGCAGCAATAGCCCTGCAAAATAGCCGTACAATGTAGGCCGTCCCCA
ATTCCTGTGCGGTTTCGATC

Downstream 100 bases:

>100_bases
GCACTCGCGTTTCCGGGTCGATCGACCCGGGGACCTATCTCCGTTTCGGACTCTTCTATCTCGGCTATTACGGCTATGTC
GGCGTGATATCGCCGTACGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMSLTEADIQIDLDRRKPGTSRHVTQRQEADQVEILSGVFEGKTTGTP
ICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDYRGGGRSSARLTAPVVAAAAIAKKWLNEQYGTEIRGYMSQL
GEVEVPFTDWKHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASHVPVGLGEPLFDKLDADIAHAMMGINAV
KGVEIGAGFDSVSQRGTVHGDELTPEGFRTNNSGGVLGGISTGQDIKVSLAIKPTSSIRTARESIDKAGSPASVETFGRH
DPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVRVDTPRIPAQAPGKS

Sequences:

>Translated_369_residues
MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMSLTEADIQIDLDRRKPGTSRHVTQRQEADQVEILSGVFEGKTTGTP
ICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDYRGGGRSSARLTAPVVAAAAIAKKWLNEQYGTEIRGYMSQL
GEVEVPFTDWKHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASHVPVGLGEPLFDKLDADIAHAMMGINAV
KGVEIGAGFDSVSQRGTVHGDELTPEGFRTNNSGGVLGGISTGQDIKVSLAIKPTSSIRTARESIDKAGSPASVETFGRH
DPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVRVDTPRIPAQAPGKS
>Mature_368_residues
SGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMSLTEADIQIDLDRRKPGTSRHVTQRQEADQVEILSGVFEGKTTGTPI
CLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDYRGGGRSSARLTAPVVAAAAIAKKWLNEQYGTEIRGYMSQLG
EVEVPFTDWKHVPENPFFAANADIVPELETYMDALRRDGDSVGARIEVVASHVPVGLGEPLFDKLDADIAHAMMGINAVK
GVEIGAGFDSVSQRGTVHGDELTPEGFRTNNSGGVLGGISTGQDIKVSLAIKPTSSIRTARESIDKAGSPASVETFGRHD
PCVGIRATPIAEAMLALVLMDHALRHRAQCGDVRVDTPRIPAQAPGKS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=64.1666666666667, Blast_Score=457, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=44.141689373297, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39559; Mature: 39428

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMSLTEADIQIDLDRRKPGTSRHVTQRQ
CCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCEEECEEEEEECCCCCCCCHHHHHHH
EADQVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDY
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCC
RGGGRSSARLTAPVVAAAAIAKKWLNEQYGTEIRGYMSQLGEVEVPFTDWKHVPENPFFA
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCCCCCCCCCCCCEE
ANADIVPELETYMDALRRDGDSVGARIEVVASHVPVGLGEPLFDKLDADIAHAMMGINAV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFDSVSQRGTVHGDELTPEGFRTNNSGGVLGGISTGQDIKVSLAIKPTSSIRT
CCEEECCCCHHHHHCCCCCCCCCCCCCCEECCCCCEEECCCCCCCEEEEEEECCCHHHHH
ARESIDKAGSPASVETFGRHDPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVRVDTPR
HHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
IPAQAPGKS
CCCCCCCCC
>Mature Secondary Structure 
SGNTLGLLFTVTTFGESHGPAIGAVVDGCPPGMSLTEADIQIDLDRRKPGTSRHVTQRQ
CCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCEEECEEEEEECCCCCCCCHHHHHHH
EADQVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDY
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCC
RGGGRSSARLTAPVVAAAAIAKKWLNEQYGTEIRGYMSQLGEVEVPFTDWKHVPENPFFA
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCCCCCCCCCCCCEE
ANADIVPELETYMDALRRDGDSVGARIEVVASHVPVGLGEPLFDKLDADIAHAMMGINAV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFDSVSQRGTVHGDELTPEGFRTNNSGGVLGGISTGQDIKVSLAIKPTSSIRT
CCEEECCCCHHHHHCCCCCCCCCCCCCCEECCCCCEEECCCCCCCEEEEEEECCCHHHHH
ARESIDKAGSPASVETFGRHDPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVRVDTPR
HHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
IPAQAPGKS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA