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The map label for this gene is ydcR [H]

Identifier: 94310071

GI number: 94310071

Start: 1233359

End: 1234786

Strand: Direct

Name: ydcR [H]

Synonym: Rmet_1126

Alternate gene names: 94310071

Gene position: 1233359-1234786 (Clockwise)

Preceding gene: 94310070

Following gene: 94310072

Centisome position: 31.4

GC content: 64.99

Gene sequence:

>1428_bases
GTGACTCTCTACGAAAAACTTGCGACCGATATCGAGGCGCTGGTCCAGCAAGGCGTATTGCTTCCGGGCGAGAAGATCCC
CTCGGTGCGGCAGGCGGCGCAGCATCATCGCCTGAGCATCACCACGGTCGTGCGTGCGTATCTGCTGCTGGAATCGCGCG
GCATCCTGGAGAGCCGGCCGCAATCGGGCTACTTCGTGCGTGCCCGGCCCGGCGAGCCACCGATCGACCTGCTCCCGACC
CGACCCGCGGCACGCCCTTCGGCGGTGGATGTGAGCGCGCTCGTGCTGTCGACGCTGCGCTCGATTCGTGTCGATGACGC
GGTGCCGCTCGGCTCGCCATATCCCGACCCCCGGCTCTACCCGTGGCAGCGCATCACGCAGTACGCCAATGCCATCGCCA
AGCGCTACGACACGTGGAGCGTGCTCGACGACCTGCCGCCGGGCGCGCCGCCACTGATTCGCCAGATCACGCGCCGTTAC
CTGGAGAACGGGCTGGCCGTCGATCCGAACGAAGTGATCGTTACGATCGGCGCCACCGAGGCCATCAACCTGTGCCTGCA
GGCCGTGGCAAAGCCGGGCGACACCATTGCCGTGGAATCGCCAACGTACTACGCGATGCTGCACGCGATCGAGCGGCTGG
GGATGCGTGCCGTGGAAGTGGCGACCGATCCCGTGAAAGGCATCGACGTGCAGGCGCTGGCGAAGCTGCTCGACGAGCGC
CCCGTGGCCGCGTGCATGGTGATGCCGAATTTCCAGAATCCGCTTGGCTTCCAGATGCCGGACGAACGCAAGCAGGCGCT
GGTGGAATTGCTGACTGCGCGCGATATTCCGGTGATCGAGAACGACGTCTATGGCGAGCTGTTTTACGGTGACGTGCATC
CGACCTCGCTCAAGTCCTACGATCGGGCCGGCATCGTGCTGCATTGCTCGTCGTTCTCGAAGACGTTGACCAATGCGTAC
CGCATCGGCTGGGCGCTGCCGGGACGGTACCGGGAAAGGGTGGAGCGGCTCAAGTTCCTGAACACGCTGACCACCTCGAC
GATTCCGCAATTGGCCATCGCCGAGTTCCTGCGCAAGGACGGCTATGACTTTCATCTGCGGCGCGTGCGCAAGGCCTATG
CGCAGCAGGCCAACATCATGGCGGCGGCGGTGCGTCGCTTCTTTCCGCAGGGCACGCGCGTGTCGCGCCCCGCTGGCGGG
TATGTGCTGTGGGTGGAGTTGCCGGAGGAGGTGGACGCGATGGCCCTTTATCACGCGGCGCTGGAGCGACGCATCACGGT
GGCGCCCGGCCACATCTTCTCGCCGGTGCCGACCTATGCCAACTGCATCCGACTTAACTACAGCAGCGCATGGACGCCAG
ACATGGAGGCGGCCGTCGTTACGCTCGGCAAGCTGGTGGCAACATTGCAGGCGCGGGAGGCAATATGA

Upstream 100 bases:

>100_bases
GAGGGTTTCGTATTACGATCTGAGCCGCTGGCGGTACCGGGCTGACGCCCGGCCGGGCACCGCCAGCCAGATCGGAAATT
ACTGGCGAAAGGTTGGCGGT

Downstream 100 bases:

>100_bases
GCGATGACGTGAACGAACAGAATGGCATCGACCCGGTGCTGGAGGCGATCCTCCGCGCGCTTTGGGAACATGCACGGGAA
GCCGGCGGCGACCTGTCGCT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTLYEKLATDIEALVQQGVLLPGEKIPSVRQAAQHHRLSITTVVRAYLLLESRGILESRPQSGYFVRARPGEPPIDLLPT
RPAARPSAVDVSALVLSTLRSIRVDDAVPLGSPYPDPRLYPWQRITQYANAIAKRYDTWSVLDDLPPGAPPLIRQITRRY
LENGLAVDPNEVIVTIGATEAINLCLQAVAKPGDTIAVESPTYYAMLHAIERLGMRAVEVATDPVKGIDVQALAKLLDER
PVAACMVMPNFQNPLGFQMPDERKQALVELLTARDIPVIENDVYGELFYGDVHPTSLKSYDRAGIVLHCSSFSKTLTNAY
RIGWALPGRYRERVERLKFLNTLTTSTIPQLAIAEFLRKDGYDFHLRRVRKAYAQQANIMAAAVRRFFPQGTRVSRPAGG
YVLWVELPEEVDAMALYHAALERRITVAPGHIFSPVPTYANCIRLNYSSAWTPDMEAAVVTLGKLVATLQAREAI

Sequences:

>Translated_475_residues
MTLYEKLATDIEALVQQGVLLPGEKIPSVRQAAQHHRLSITTVVRAYLLLESRGILESRPQSGYFVRARPGEPPIDLLPT
RPAARPSAVDVSALVLSTLRSIRVDDAVPLGSPYPDPRLYPWQRITQYANAIAKRYDTWSVLDDLPPGAPPLIRQITRRY
LENGLAVDPNEVIVTIGATEAINLCLQAVAKPGDTIAVESPTYYAMLHAIERLGMRAVEVATDPVKGIDVQALAKLLDER
PVAACMVMPNFQNPLGFQMPDERKQALVELLTARDIPVIENDVYGELFYGDVHPTSLKSYDRAGIVLHCSSFSKTLTNAY
RIGWALPGRYRERVERLKFLNTLTTSTIPQLAIAEFLRKDGYDFHLRRVRKAYAQQANIMAAAVRRFFPQGTRVSRPAGG
YVLWVELPEEVDAMALYHAALERRITVAPGHIFSPVPTYANCIRLNYSSAWTPDMEAAVVTLGKLVATLQAREAI
>Mature_474_residues
TLYEKLATDIEALVQQGVLLPGEKIPSVRQAAQHHRLSITTVVRAYLLLESRGILESRPQSGYFVRARPGEPPIDLLPTR
PAARPSAVDVSALVLSTLRSIRVDDAVPLGSPYPDPRLYPWQRITQYANAIAKRYDTWSVLDDLPPGAPPLIRQITRRYL
ENGLAVDPNEVIVTIGATEAINLCLQAVAKPGDTIAVESPTYYAMLHAIERLGMRAVEVATDPVKGIDVQALAKLLDERP
VAACMVMPNFQNPLGFQMPDERKQALVELLTARDIPVIENDVYGELFYGDVHPTSLKSYDRAGIVLHCSSFSKTLTNAYR
IGWALPGRYRERVERLKFLNTLTTSTIPQLAIAEFLRKDGYDFHLRRVRKAYAQQANIMAAAVRRFFPQGTRVSRPAGGY
VLWVELPEEVDAMALYHAALERRITVAPGHIFSPVPTYANCIRLNYSSAWTPDMEAAVVTLGKLVATLQAREAI

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=317, Percent_Identity=27.7602523659306, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI33469970, Length=317, Percent_Identity=27.7602523659306, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI4507369, Length=296, Percent_Identity=25, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1787710, Length=466, Percent_Identity=41.2017167381974, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI1790797, Length=473, Percent_Identity=37.4207188160677, Blast_Score=322, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6321000, Length=317, Percent_Identity=22.397476340694, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=315, Percent_Identity=24.7619047619048, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356535, Length=296, Percent_Identity=25.3378378378378, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52803; Mature: 52671

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLYEKLATDIEALVQQGVLLPGEKIPSVRQAAQHHRLSITTVVRAYLLLESRGILESRP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHCCC
QSGYFVRARPGEPPIDLLPTRPAARPSAVDVSALVLSTLRSIRVDDAVPLGSPYPDPRLY
CCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PWQRITQYANAIAKRYDTWSVLDDLPPGAPPLIRQITRRYLENGLAVDPNEVIVTIGATE
CHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCHH
AINLCLQAVAKPGDTIAVESPTYYAMLHAIERLGMRAVEVATDPVKGIDVQALAKLLDER
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHCC
PVAACMVMPNFQNPLGFQMPDERKQALVELLTARDIPVIENDVYGELFYGDVHPTSLKSY
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHCC
DRAGIVLHCSSFSKTLTNAYRIGWALPGRYRERVERLKFLNTLTTSTIPQLAIAEFLRKD
CCCCEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYDFHLRRVRKAYAQQANIMAAAVRRFFPQGTRVSRPAGGYVLWVELPEEVDAMALYHAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHH
LERRITVAPGHIFSPVPTYANCIRLNYSSAWTPDMEAAVVTLGKLVATLQAREAI
HHCEEEECCCCCCCCCCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLYEKLATDIEALVQQGVLLPGEKIPSVRQAAQHHRLSITTVVRAYLLLESRGILESRP
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHCCC
QSGYFVRARPGEPPIDLLPTRPAARPSAVDVSALVLSTLRSIRVDDAVPLGSPYPDPRLY
CCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PWQRITQYANAIAKRYDTWSVLDDLPPGAPPLIRQITRRYLENGLAVDPNEVIVTIGATE
CHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCHH
AINLCLQAVAKPGDTIAVESPTYYAMLHAIERLGMRAVEVATDPVKGIDVQALAKLLDER
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHCC
PVAACMVMPNFQNPLGFQMPDERKQALVELLTARDIPVIENDVYGELFYGDVHPTSLKSY
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHCC
DRAGIVLHCSSFSKTLTNAYRIGWALPGRYRERVERLKFLNTLTTSTIPQLAIAEFLRKD
CCCCEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYDFHLRRVRKAYAQQANIMAAAVRRFFPQGTRVSRPAGGYVLWVELPEEVDAMALYHAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHH
LERRITVAPGHIFSPVPTYANCIRLNYSSAWTPDMEAAVVTLGKLVATLQAREAI
HHCEEEECCCCCCCCCCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]