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The map label for this gene is slyD [H]

Identifier: 94310018

GI number: 94310018

Start: 1165153

End: 1165713

Strand: Direct

Name: slyD [H]

Synonym: Rmet_1073

Alternate gene names: 94310018

Gene position: 1165153-1165713 (Clockwise)

Preceding gene: 94310015

Following gene: 94310024

Centisome position: 29.66

GC content: 61.14

Gene sequence:

>561_bases
ATGCGGAATCGCTCATGGAGTCAAGAATTGAAAATCGCTAAGAATACGGTGGTGTCCGTGGTGTATAAGCTGTCGGACGC
GCAGGGCAATCTGATCGAAGAGTCGGATGAGCCCATGGTCTATTTGCACGGCGGATATGATGGCACGTTCCCCAAGATCG
AGGAAGCGCTGGACGGCCACGACGCCGGCTTCGAGACCGAGTTGCAGCTGGAACCGGAAGAGGCGTTTGGCGACTACGAC
GCCGAACTCGTGAAGGTGGAGCCGCGTGATCGTTTCCCGGAGCCGCTCGAAGTGGGCATGCAGTTCGAGGGCGTGCCCGA
GGACGGTGACGACGAAGATTCGATCATCTACACGGTGACGGACGTCGCCGAGGACAAGGTCGTGCTTGACGGCAATCACC
CGCTGGCCGGCATGGCGCTGCGCTTCTGGCTGAAGGTATCGGAAGTCCGCGAGGCGACGAGCGAGGAAGTCGAGCACGGT
CACGCGCACGGCGCTTCGGGCATCGAAGTGGTGGACGAAGACGAGGACGGCGAGGACGAGGCTCCTCGCACGCTGCACTA
A

Upstream 100 bases:

>100_bases
TGCCAGATATCACGCATGAAGGCTGAGGGCGTCATGCCGCCGAGCAGGGTGAGCGGCGCGTCGGGATCGACAGGTTCCGG
AGGCAAGGCCTGCGCGTATA

Downstream 100 bases:

>100_bases
GTCTCACAACACGAGCGATCCGCGATAGGTCATCGCGAACATGAAAAAGCCGGCATTTGCCGGCTTTTTCATTTTGTCCT
CTTGTTGATGAATATCAATT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase 2

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MRNRSWSQELKIAKNTVVSVVYKLSDAQGNLIEESDEPMVYLHGGYDGTFPKIEEALDGHDAGFETELQLEPEEAFGDYD
AELVKVEPRDRFPEPLEVGMQFEGVPEDGDDEDSIIYTVTDVAEDKVVLDGNHPLAGMALRFWLKVSEVREATSEEVEHG
HAHGASGIEVVDEDEDGEDEAPRTLH

Sequences:

>Translated_186_residues
MRNRSWSQELKIAKNTVVSVVYKLSDAQGNLIEESDEPMVYLHGGYDGTFPKIEEALDGHDAGFETELQLEPEEAFGDYD
AELVKVEPRDRFPEPLEVGMQFEGVPEDGDDEDSIIYTVTDVAEDKVVLDGNHPLAGMALRFWLKVSEVREATSEEVEHG
HAHGASGIEVVDEDEDGEDEAPRTLH
>Mature_186_residues
MRNRSWSQELKIAKNTVVSVVYKLSDAQGNLIEESDEPMVYLHGGYDGTFPKIEEALDGHDAGFETELQLEPEEAFGDYD
AELVKVEPRDRFPEPLEVGMQFEGVPEDGDDEDSIIYTVTDVAEDKVVLDGNHPLAGMALRFWLKVSEVREATSEEVEHG
HAHGASGIEVVDEDEDGEDEAPRTLH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=152, Percent_Identity=38.1578947368421, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 20715; Mature: 20715

Theoretical pI: Translated: 3.92; Mature: 3.92

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNRSWSQELKIAKNTVVSVVYKLSDAQGNLIEESDEPMVYLHGGYDGTFPKIEEALDGH
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCC
DAGFETELQLEPEEAFGDYDAELVKVEPRDRFPEPLEVGMQFEGVPEDGDDEDSIIYTVT
CCCCCEEEEECHHHHCCCCCCEEEEECCCCCCCCHHHHCEEECCCCCCCCCCCCEEEEEE
DVAEDKVVLDGNHPLAGMALRFWLKVSEVREATSEEVEHGHAHGASGIEVVDEDEDGEDE
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
APRTLH
CCCCCC
>Mature Secondary Structure
MRNRSWSQELKIAKNTVVSVVYKLSDAQGNLIEESDEPMVYLHGGYDGTFPKIEEALDGH
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCC
DAGFETELQLEPEEAFGDYDAELVKVEPRDRFPEPLEVGMQFEGVPEDGDDEDSIIYTVT
CCCCCEEEEECHHHHCCCCCCEEEEECCCCCCCCHHHHCEEECCCCCCCCCCCCEEEEEE
DVAEDKVVLDGNHPLAGMALRFWLKVSEVREATSEEVEHGHAHGASGIEVVDEDEDGEDE
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
APRTLH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]