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The map label for this gene is gntK [H]

Identifier: 94309991

GI number: 94309991

Start: 1139122

End: 1139637

Strand: Direct

Name: gntK [H]

Synonym: Rmet_1046

Alternate gene names: 94309991

Gene position: 1139122-1139637 (Clockwise)

Preceding gene: 94309990

Following gene: 335055513

Centisome position: 29.0

GC content: 66.09

Gene sequence:

>516_bases
ATGATCTATATCCTGATGGGCGTTTCCGGCAGCGGCAAGAGCACGGTCGGCCAGATGCTGGCGGACCGTCTTCATTGCGG
TTTCCACGACGCGGACAGCTTCCACAGCGACGCCAACAAGGCCAAGATGCACGCCGGCATCCCATTGACCGATGACGACC
GCTGGCCCTGGCTGGACGCGATGCGGGCCGCCATCGACGCCGCCCGCGCCGAGGGCCGCACCCACGTGTTCACATGTTCG
GCGCTGCGCCAGGTCTATCGGGACCGCCTGCTGCCGGCCGACGGCGGCGTGACCTTCGTGTTCATGAAGGGCGACGCCTC
GACGATCGGCAGCCGCCTGTCCGCGCGCACCGACCATTTTTTCAATCCCGCGCTGCTCCAGAGCCAGTTCGAGACCCTGG
AGGAGCCTTGCGACGCGCTCGTGCTCGATATTCGCCGCACTCCCGAGGCACTGGTCGAGGATATTCTGGAAAAATGCCCG
CCGGCATCGGCCGCCTGTTCCGGGAAGGCGCCCTGA

Upstream 100 bases:

>100_bases
ACGCGCTGCACCCCGGAAGCACCTTCGCGCCACATCGACGTGGCCGAAGGCTACCGACAAGGATGGCAACACCATCCGAC
ACATGATCGATGGAGCAGAC

Downstream 100 bases:

>100_bases
ATAACTTGTGGCTGGCAAGCATCTTGCTAAATCGTTTCTGTGTGCCGGCGCGTGTCACTTGTGTGCAACCCCTTGCGGGT
TCAGCCGGTACGGATATGCT

Product: gluconate kinase 2; gluconate transport, GNT I system

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MIYILMGVSGSGKSTVGQMLADRLHCGFHDADSFHSDANKAKMHAGIPLTDDDRWPWLDAMRAAIDAARAEGRTHVFTCS
ALRQVYRDRLLPADGGVTFVFMKGDASTIGSRLSARTDHFFNPALLQSQFETLEEPCDALVLDIRRTPEALVEDILEKCP
PASAACSGKAP

Sequences:

>Translated_171_residues
MIYILMGVSGSGKSTVGQMLADRLHCGFHDADSFHSDANKAKMHAGIPLTDDDRWPWLDAMRAAIDAARAEGRTHVFTCS
ALRQVYRDRLLPADGGVTFVFMKGDASTIGSRLSARTDHFFNPALLQSQFETLEEPCDALVLDIRRTPEALVEDILEKCP
PASAACSGKAP
>Mature_171_residues
MIYILMGVSGSGKSTVGQMLADRLHCGFHDADSFHSDANKAKMHAGIPLTDDDRWPWLDAMRAAIDAARAEGRTHVFTCS
ALRQVYRDRLLPADGGVTFVFMKGDASTIGSRLSARTDHFFNPALLQSQFETLEEPCDALVLDIRRTPEALVEDILEKCP
PASAACSGKAP

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=175, Percent_Identity=38.8571428571429, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI87082265, Length=160, Percent_Identity=45.625, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1790719, Length=167, Percent_Identity=39.5209580838323, Blast_Score=116, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25146487, Length=140, Percent_Identity=45, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320454, Length=160, Percent_Identity=33.125, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18622; Mature: 18622

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYILMGVSGSGKSTVGQMLADRLHCGFHDADSFHSDANKAKMHAGIPLTDDDRWPWLDA
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCHHHH
MRAAIDAARAEGRTHVFTCSALRQVYRDRLLPADGGVTFVFMKGDASTIGSRLSARTDHF
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
FNPALLQSQFETLEEPCDALVLDIRRTPEALVEDILEKCPPASAACSGKAP
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIYILMGVSGSGKSTVGQMLADRLHCGFHDADSFHSDANKAKMHAGIPLTDDDRWPWLDA
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCHHHH
MRAAIDAARAEGRTHVFTCSALRQVYRDRLLPADGGVTFVFMKGDASTIGSRLSARTDHF
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
FNPALLQSQFETLEEPCDALVLDIRRTPEALVEDILEKCPPASAACSGKAP
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]