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The map label for this gene is yngJ [H]

Identifier: 94309913

GI number: 94309913

Start: 1051692

End: 1052954

Strand: Reverse

Name: yngJ [H]

Synonym: Rmet_0968

Alternate gene names: 94309913

Gene position: 1052954-1051692 (Counterclockwise)

Preceding gene: 94309916

Following gene: 94309912

Centisome position: 26.81

GC content: 64.37

Gene sequence:

>1263_bases
ATGCAATTCGAGTACACGCCCAAGGTCAAGGAAATGCAGGCCAGGCTGCTGGCGTTCTTCGACCAGCACATTTACCCCAA
CGAGAAGCGCTTCTACGCCGAGATCCAGGCCAATCGCGCGGCCGGCAACGCGTGGATTCCGACCAAGGTGATCGAGGAAC
TGAAGCCGCTGGCGCGTGAAGCCGGGCTCTGGAACCTGTTCCTGCCGCGTTCGAAGCGCGCGCCGGAAGGGCTGTCGAAC
CTCGAATACGCGCCGATGTGCGAAATCATGGGCCGTGTGCCCTGGTCGGCCGAGGTGTTCAACTGCGCCGCGCCCGATAC
CGGCAACATGGAAACGCTCGAGCGCTACGCCTCGGAAGAACTGAAGGACGAGTGGCTGGAGCCCCTGCTGCGCGGCGAGA
TCCGCTCGGCGTTCCTGATGACCGAGCCGGCCGTGGCTTCGTCGGACGCCACGAACATCGAGTGCCGCATCGAACGCGAT
GGCGATCACTACGTGATCAACGGCACCAAGTGGTGGTCGTCGGGCGCCGGCGATCCCCGCTGCAAGGTCTACATCGTGAT
GGGCAAGACCGATCCGAATGCTGGCCGTCATGAACAGCAGTCGATGATCGTGGTGCCGGCCGATACCCCGGGCATCACCA
TCAAGCGCTTCCTGCCGGTGTTCGGCTACGACGACGCTCCGCACGGCCACATGGAAATCGAACTGAAGAATGTGCGCGTG
CCGGTCAGCAACATCCTGTTGGGTGAAGGCCGCGGCTTCGAGATCGCCCAGGGCCGCCTCGGCCCGGGCCGTATCCACCA
CTGCATGCGCAGCATCGGCGTGGCGGAACGCGCACTGGAACTGATGTGCAAGCGCAGTCTGGAGCGTGTGGCATTCGGCA
AGCAGATCGCCCGCCAGGGCGTGACGCAGGAACGCATCGCCGAAGCCCGCTGCGACATCGAAATGGCGCGCCTGCTGACG
CTGAAGGCCGCGTACATGATGGACACGGTCGGCAACAAGATTGCCAAGGCCGAGATTGCGATGATCAAGGTGGTGGCGCC
GAACGTGGCCCTGCGCGTGATCGACTGGGCCATCCAGGTGCACGGCGCCGCGGGTGTGTCGGGCGACTTCCCGCTGGCCA
ACTGGTGGGCGCACCAGCGCACGCTGCGTCTGGCCGATGGTCCGGACGAGGTACACCGCAATGCGATCGCCAAGCTGGAA
CTGGCCAAGCACATGAAGCTGAACCCGGACAGCATCCAGATGCCGATCACGCGCGGCTCGTGA

Upstream 100 bases:

>100_bases
CTAGAAAATTCATTTTTCTTATTGATCAGGTTCCGCTAGAGTAACCAACGTCGGCACACCGTGCCTGGTACCACACCCAA
AAGGTAACCGAGGAGACCTC

Downstream 100 bases:

>100_bases
TGCGCTGCCGCTGAAACAGGAAAGCCCGACAGGTCACTGTCGGGCTTTTTTTCTTGCCGGGCTGGACACCGAAGCACCAT
CCCACGAACAGATCATCCAT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MQFEYTPKVKEMQARLLAFFDQHIYPNEKRFYAEIQANRAAGNAWIPTKVIEELKPLAREAGLWNLFLPRSKRAPEGLSN
LEYAPMCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEELKDEWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERD
GDHYVINGTKWWSSGAGDPRCKVYIVMGKTDPNAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRSLERVAFGKQIARQGVTQERIAEARCDIEMARLLT
LKAAYMMDTVGNKIAKAEIAMIKVVAPNVALRVIDWAIQVHGAAGVSGDFPLANWWAHQRTLRLADGPDEVHRNAIAKLE
LAKHMKLNPDSIQMPITRGS

Sequences:

>Translated_420_residues
MQFEYTPKVKEMQARLLAFFDQHIYPNEKRFYAEIQANRAAGNAWIPTKVIEELKPLAREAGLWNLFLPRSKRAPEGLSN
LEYAPMCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEELKDEWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERD
GDHYVINGTKWWSSGAGDPRCKVYIVMGKTDPNAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRSLERVAFGKQIARQGVTQERIAEARCDIEMARLLT
LKAAYMMDTVGNKIAKAEIAMIKVVAPNVALRVIDWAIQVHGAAGVSGDFPLANWWAHQRTLRLADGPDEVHRNAIAKLE
LAKHMKLNPDSIQMPITRGS
>Mature_420_residues
MQFEYTPKVKEMQARLLAFFDQHIYPNEKRFYAEIQANRAAGNAWIPTKVIEELKPLAREAGLWNLFLPRSKRAPEGLSN
LEYAPMCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEELKDEWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERD
GDHYVINGTKWWSSGAGDPRCKVYIVMGKTDPNAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRSLERVAFGKQIARQGVTQERIAEARCDIEMARLLT
LKAAYMMDTVGNKIAKAEIAMIKVVAPNVALRVIDWAIQVHGAAGVSGDFPLANWWAHQRTLRLADGPDEVHRNAIAKLE
LAKHMKLNPDSIQMPITRGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=406, Percent_Identity=56.8965517241379, Blast_Score=461, Evalue=1e-130,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=56.8238213399504, Blast_Score=454, Evalue=1e-128,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=56.8238213399504, Blast_Score=454, Evalue=1e-128,
Organism=Homo sapiens, GI21361497, Length=382, Percent_Identity=28.5340314136126, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4501859, Length=322, Percent_Identity=29.8136645962733, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557231, Length=414, Percent_Identity=26.0869565217391, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI187960098, Length=414, Percent_Identity=26.0869565217391, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI4557233, Length=321, Percent_Identity=29.9065420560748, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI7656849, Length=286, Percent_Identity=28.6713286713287, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI76496475, Length=413, Percent_Identity=26.1501210653753, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4557235, Length=413, Percent_Identity=26.1501210653753, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226958412, Length=324, Percent_Identity=25.6172839506173, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=25.6172839506173, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=23.961661341853, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4503943, Length=288, Percent_Identity=23.2638888888889, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI7669494, Length=266, Percent_Identity=24.4360902255639, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081958, Length=305, Percent_Identity=28.1967213114754, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786223, Length=298, Percent_Identity=24.496644295302, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=54.2465753424658, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17534899, Length=407, Percent_Identity=28.992628992629, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17569725, Length=422, Percent_Identity=27.4881516587678, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=287, Percent_Identity=28.9198606271777, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17533517, Length=291, Percent_Identity=28.8659793814433, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=284, Percent_Identity=29.5774647887324, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=371, Percent_Identity=28.3018867924528, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=26.1764705882353, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=284, Percent_Identity=28.169014084507, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=324, Percent_Identity=25.3086419753086, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=296, Percent_Identity=25.3378378378378, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=271, Percent_Identity=26.9372693726937, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=27.7153558052434, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=189, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=25.9109311740891, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=181, Percent_Identity=28.7292817679558, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646207, Length=351, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24666513, Length=288, Percent_Identity=30.9027777777778, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281363737, Length=399, Percent_Identity=26.5664160401003, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24660351, Length=284, Percent_Identity=29.9295774647887, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=28.6103542234332, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21355753, Length=352, Percent_Identity=23.8636363636364, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19920834, Length=321, Percent_Identity=24.2990654205607, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 47063; Mature: 47063

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFEYTPKVKEMQARLLAFFDQHIYPNEKRFYAEIQANRAAGNAWIPTKVIEELKPLARE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
AGLWNLFLPRSKRAPEGLSNLEYAPMCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEE
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHH
LKDEWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERDGDHYVINGTKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCEEEEECEEECCCCCCCCC
CKVYIVMGKTDPNAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHCCCCCCCCCEEEEEEEEEEC
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRSLERVAFGKQIARQG
CHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTQERIAEARCDIEMARLLTLKAAYMMDTVGNKIAKAEIAMIKVVAPNVALRVIDWAIQV
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCCEEEEEEEEEEE
HGAAGVSGDFPLANWWAHQRTLRLADGPDEVHRNAIAKLELAKHMKLNPDSIQMPITRGS
ECCCCCCCCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEECEECCC
>Mature Secondary Structure
MQFEYTPKVKEMQARLLAFFDQHIYPNEKRFYAEIQANRAAGNAWIPTKVIEELKPLARE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
AGLWNLFLPRSKRAPEGLSNLEYAPMCEIMGRVPWSAEVFNCAAPDTGNMETLERYASEE
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHH
LKDEWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERDGDHYVINGTKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCEEEEECEEECCCCCCCCC
CKVYIVMGKTDPNAGRHEQQSMIVVPADTPGITIKRFLPVFGYDDAPHGHMEIELKNVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHCCCCCCCCCEEEEEEEEEEC
PVSNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRSLERVAFGKQIARQG
CHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTQERIAEARCDIEMARLLTLKAAYMMDTVGNKIAKAEIAMIKVVAPNVALRVIDWAIQV
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCCEEEEEEEEEEE
HGAAGVSGDFPLANWWAHQRTLRLADGPDEVHRNAIAKLELAKHMKLNPDSIQMPITRGS
ECCCCCCCCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEECEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]