Click here to switch to the map view.

The map label for this gene is nuoC [H]

Identifier: 94309874

GI number: 94309874

Start: 1013397

End: 1013996

Strand: Direct

Name: nuoC [H]

Synonym: Rmet_0929

Alternate gene names: 94309874

Gene position: 1013397-1013996 (Clockwise)

Preceding gene: 94309873

Following gene: 94309875

Centisome position: 25.8

GC content: 62.33

Gene sequence:

>600_bases
ATGGCGAACCTGGATACCCTCAAGGCTGCGCTCGAAAAGGTCCTCGGCAAGCGCGTGCAGAACCTGATCGAGGCCACCGG
CGAACTGACGCTGATCGTCAAGGCCGCCGACTATCTCGAAGTCGCGCGTCTGCTGCGTGACGATCCCTCGCTGCGTTTCG
AACAGCTACTCGACCTGTGCGGCGTGGACTATTCCGACTACGCCGAAGGCGCCTGGGACGGCCTGCGCTTTGCCGCTGTC
TCGCAGCTGCTGTCGGTAACGCACAACTGGCGTCTGCGTCTGCGCGTGTTCGCGCCGGACGATGATTTCCCGGTGCTGCC
GTCGGTCATCAACGTCTGGAACTCGGTGAACTGGTTCGAGCGCGAAGCGTTCGATTTCTACGGCATCGTGTTCGAAGGCC
ATCCGGATCTGCGCCGTATCCTGACCGACTACGGTTTCGTCGGCCACCCGTTCCGCAAGGATTTCCCAGTCTCGGGCTAC
GTCGAAATGCGCTACGACCCGGAACAGAAGCGGGTCATCTACCAGCCGGTGACGATCGAGCCGCGCGAAGTCACGCCGCG
CGTGATTCGCGAGGAAAACTACGGCGGCACGCAGCACTGA

Upstream 100 bases:

>100_bases
GTTCCGGGCTGCCCGCCGACGGCGGAAGCGCTGATCTACGGCGTGATCCAGCTCCAGAACAAGATCAAGCGTACCAATAC
TATCGCGCGCAAGGGCTGAT

Downstream 100 bases:

>100_bases
GATCGCGTCATGGCAGATATCAAGAACTACACCCTCAACTTCGGCCCCCAACACCCTGCAGCGCACGGCGTGCTGCGTCT
GGTGCTTGAACTGGACGGCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MANLDTLKAALEKVLGKRVQNLIEATGELTLIVKAADYLEVARLLRDDPSLRFEQLLDLCGVDYSDYAEGAWDGLRFAAV
SQLLSVTHNWRLRLRVFAPDDDFPVLPSVINVWNSVNWFEREAFDFYGIVFEGHPDLRRILTDYGFVGHPFRKDFPVSGY
VEMRYDPEQKRVIYQPVTIEPREVTPRVIREENYGGTQH

Sequences:

>Translated_199_residues
MANLDTLKAALEKVLGKRVQNLIEATGELTLIVKAADYLEVARLLRDDPSLRFEQLLDLCGVDYSDYAEGAWDGLRFAAV
SQLLSVTHNWRLRLRVFAPDDDFPVLPSVINVWNSVNWFEREAFDFYGIVFEGHPDLRRILTDYGFVGHPFRKDFPVSGY
VEMRYDPEQKRVIYQPVTIEPREVTPRVIREENYGGTQH
>Mature_198_residues
ANLDTLKAALEKVLGKRVQNLIEATGELTLIVKAADYLEVARLLRDDPSLRFEQLLDLCGVDYSDYAEGAWDGLRFAAVS
QLLSVTHNWRLRLRVFAPDDDFPVLPSVINVWNSVNWFEREAFDFYGIVFEGHPDLRRILTDYGFVGHPFRKDFPVSGYV
EMRYDPEQKRVIYQPVTIEPREVTPRVIREENYGGTQH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=178, Percent_Identity=41.0112359550562, Blast_Score=137, Evalue=6e-33,
Organism=Escherichia coli, GI145693162, Length=134, Percent_Identity=35.0746268656716, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990788, Length=165, Percent_Identity=43.030303030303, Blast_Score=131, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32563621, Length=177, Percent_Identity=41.8079096045198, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24656494, Length=170, Percent_Identity=41.7647058823529, Blast_Score=134, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 23007; Mature: 22876

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLDTLKAALEKVLGKRVQNLIEATGELTLIVKAADYLEVARLLRDDPSLRFEQLLDLC
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHH
GVDYSDYAEGAWDGLRFAAVSQLLSVTHNWRLRLRVFAPDDDFPVLPSVINVWNSVNWFE
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHH
REAFDFYGIVFEGHPDLRRILTDYGFVGHPFRKDFPVSGYVEMRYDPEQKRVIYQPVTIE
HHHHHEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
PREVTPRVIREENYGGTQH
CHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
ANLDTLKAALEKVLGKRVQNLIEATGELTLIVKAADYLEVARLLRDDPSLRFEQLLDLC
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHH
GVDYSDYAEGAWDGLRFAAVSQLLSVTHNWRLRLRVFAPDDDFPVLPSVINVWNSVNWFE
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHH
REAFDFYGIVFEGHPDLRRILTDYGFVGHPFRKDFPVSGYVEMRYDPEQKRVIYQPVTIE
HHHHHEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
PREVTPRVIREENYGGTQH
CHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA