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The map label for this gene is pepN [H]

Identifier: 94309821

GI number: 94309821

Start: 957196

End: 959889

Strand: Reverse

Name: pepN [H]

Synonym: Rmet_0876

Alternate gene names: 94309821

Gene position: 959889-957196 (Counterclockwise)

Preceding gene: 335055509

Following gene: 94309820

Centisome position: 24.44

GC content: 65.03

Gene sequence:

>2694_bases
ATGCTGCGCACCGATACGCCCGTCACCGTCTATCGCAAGGACTATACTCCGCCCGCTTTCGCCATCGACCACGTGGATCT
CGTGCTCGACCTCGATCCGCAGCGTACCGTCGTCACCAGCACGCTGAAGATCCAGCGCACCGGCACGGCCGACGCGCCGC
TGGTTCTGGCCGGCGAGGAGCTGGAACTGGTTGGCGTGCGCCTCGATGGCCAGCCGTTCTCCGGCGTCAAGCAGGACGGC
GACTCGCTGACCCTGACTGGCCTGCCGGGAACTGGCACGCTGGAAATCACCACGGCCTGCAATCCCGCCGCCAATACCAC
GCTGTCCGGCCTGTACGTCTCCAACGGCAACTTCTTCACCCAGTGCGAAGCCGAGGGCTTTCGCCGCATCACGTATTTCC
TGGATCGCCCGGATGTGATGACGACCTACCGCGTTACGCTGCGCGCCGATCGCGCCGCAAGCCCGGTACTGCTTTCGAAC
GGCAACCTGCTCTCGCAACGCGATCTGCCGGATGGCAAACACGAAGCCGTCTGGGAAGACCCGTTCCGCAAGCCGTCATA
CCTGTTCGCGCTCGTGGCCGGCAAGCTCGAGCGCATCGAGCAAACCATCGTTTCGGCATCGGGCAAGCAAAAGCTGCTGC
AAGTCTGGGTCGAGCCGCAGGACCTGGACAAGACGCGTCACGCGATGGACTCGCTGGTTCACGCGATCCGCTGGGACGAG
CAGCGCTTCGGCCTGGAACTTGACCTCGACCGTTTCATGATCGTCGCCGTGGGCGACTTCAACATGGGGGCGATGGAAAA
CAAGGGCCTGAACATCTTCAACACCAAGTATGTGCTGGCCAACGCCCAGACCGCGACGGATGTCGACTTCGCCAATATCG
AATCGGTGGTGGCCCACGAGTACTTCCATAACTGGACCGGCAACCGCGTGACCTGCCGCGACTGGTTCCAGTTGTCGCTC
AAGGAAGGCCTGACCGTGTTCCGCGACCAGGAATTCTCGGCCGACATGATGGGCTCGGAATCGGGCCGCGCGGTCAAGCG
CATCGAGGATGTGCGCGTGCTGCGCCAGGTGCAGTTCCCCGAGGATGCGGGTCCGATGGCCCACCCGGTGCGCCCGGACA
GCTACGAGGAAATCAACAACTTCTACACGGTCACGGTCTACGAGAAAGGCGCCGAAGTCGTGCGGATGTACCAGACTCTG
CTTGGCCGTGACGGCTTCCGCAAGGGGATGGACCTGTACTTCCAGCGTCATGACGGCCAGGCGGTGACATGCGACGACTT
CCGCGCGGCGATGGCTGACGCGAACGGCCGCGACCTGAAGCAGTTCGGCCTCTGGTACAGCCAGGCTGGCACGCCCGTGG
TCACGGTCAAGACCGCGTGGGACGGCGCCTCCGGCACGCTGACGCTGACGTTGTCGCAGCGCTGCCCGAAGGTCGGCATC
GAAACGCGCGCTGGCATGCCGGACAAGCAACCGTTCCACATCCCGTTCGCGCTCGGCCTGATCGACGCGGAAGGCAATGA
CCTGCCGCTGCAACGCGAAGGGGAACCCAAGGCAGGCGCGAGCACGCGCGTGCTCGATTTCACGCAGGCCGAGCAGACCT
TCCGCTTCATCAACCTGCCTCGCGGTGGCAAGGCGCCATTGCCCTCGCTGCTGCGTAATTTCTCGGCACCAGTCGTTGTC
GATTACGAATACAGCGATGCGGAACTGACATTTCTTCTCTCGCACGACACCGACGCATTCAACCGCTGGGAAGCCGGCCA
ACGCCTGGCCACGCGCGCGCTACTGCATCTGGTGGCCGACGTCCAGGCCAATCGTGAACTGAAGCTCGACCCGGCGCTGG
TGTCGGCGTTCCGCAGCGTGCTCACCGATGGCGCGCTGAATCCCGCCTTCCGCGAACAGGCACTGATGCTCCCCGCGGAG
GCCTATCTGGCCGAACGCATGGGCGTGGCCGACCCGACGGCGATTCACCGCGCACGTCTGTTCCTGCGCGAAGGCCTGGC
GCGCACGCTCAAGGCCGAATGGCTGGCCGCATACGAGGCCAACGCGACACCGGGCGAATACAGCCCCGATGCCGACTCGA
TGGCCCGTCGCGCGCTGCGCAATCTCGCGCTCGGCTATCTGGCCGACAGCGGAGACGCCGACATGCAGGCACTTGCGGAC
CGCCACTACCAGCAGAGCGACAACATGACAGACCGCTTCGCCGCGCTGTCTGCGCTGGTCAACAGCTTCGCACCGGGCCG
CGAACACGCGCTGGCCGATTTCTACGAGCGCTTCGAGGACGACGCGCTGGTCATCGACAAGTGGTTCTCGCTGCAGGGAA
TGCAGCGCGGCGAAGTTGGCCCGCACGCGGGCAAGCGCACCATTGATACCGTGCGCGCGCTGATGCAGCATCCGGCCTTC
AATCTGCGCAACCCGAATCGCGCCCGTTCGCTGATCTTCAGCTTCTGCTCGGGCAACCCAGCGCAGTTCCACGCCGAGGA
CGGCTCGGGCTACGCATTCTGGGCCGACCAGGTACTGGCGCTGGATGCGATCAACCCGCAGGTGGCCGCGCGCCTGGCAC
GCGTCATGGACCGCTGGCAGAAGTACGAGATGCCGCTGCGCGAACGGATGCGCGCGGCGCTGGAACGCGTGGCCGCCTCG
TCGACGCTGTCGCGCGATGTGCGCGAGATCGTCAGCAAGGCCCTGTCGGCCTGA

Upstream 100 bases:

>100_bases
CATTGCCCGAACCCCTTGGCTACAATGAGGGCTTCGAGGGCCGTCGCAATCTTCAGCACGCCGCCCGCCCCCCCCGGTCA
CTCCGAAGACAGGATTCCCC

Downstream 100 bases:

>100_bases
CCCGGAAAGTGGCATGTCCGCAGCGGCACACATGTAGAATTGCGGCCATCCAAGGAGAACCCCACCATGACACGCATCAG
CCTCACCCGCTATCTGGTCG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 897; Mature: 897

Protein sequence:

>897_residues
MLRTDTPVTVYRKDYTPPAFAIDHVDLVLDLDPQRTVVTSTLKIQRTGTADAPLVLAGEELELVGVRLDGQPFSGVKQDG
DSLTLTGLPGTGTLEITTACNPAANTTLSGLYVSNGNFFTQCEAEGFRRITYFLDRPDVMTTYRVTLRADRAASPVLLSN
GNLLSQRDLPDGKHEAVWEDPFRKPSYLFALVAGKLERIEQTIVSASGKQKLLQVWVEPQDLDKTRHAMDSLVHAIRWDE
QRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAQTATDVDFANIESVVAHEYFHNWTGNRVTCRDWFQLSL
KEGLTVFRDQEFSADMMGSESGRAVKRIEDVRVLRQVQFPEDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTL
LGRDGFRKGMDLYFQRHDGQAVTCDDFRAAMADANGRDLKQFGLWYSQAGTPVVTVKTAWDGASGTLTLTLSQRCPKVGI
ETRAGMPDKQPFHIPFALGLIDAEGNDLPLQREGEPKAGASTRVLDFTQAEQTFRFINLPRGGKAPLPSLLRNFSAPVVV
DYEYSDAELTFLLSHDTDAFNRWEAGQRLATRALLHLVADVQANRELKLDPALVSAFRSVLTDGALNPAFREQALMLPAE
AYLAERMGVADPTAIHRARLFLREGLARTLKAEWLAAYEANATPGEYSPDADSMARRALRNLALGYLADSGDADMQALAD
RHYQQSDNMTDRFAALSALVNSFAPGREHALADFYERFEDDALVIDKWFSLQGMQRGEVGPHAGKRTIDTVRALMQHPAF
NLRNPNRARSLIFSFCSGNPAQFHAEDGSGYAFWADQVLALDAINPQVAARLARVMDRWQKYEMPLRERMRAALERVAAS
STLSRDVREIVSKALSA

Sequences:

>Translated_897_residues
MLRTDTPVTVYRKDYTPPAFAIDHVDLVLDLDPQRTVVTSTLKIQRTGTADAPLVLAGEELELVGVRLDGQPFSGVKQDG
DSLTLTGLPGTGTLEITTACNPAANTTLSGLYVSNGNFFTQCEAEGFRRITYFLDRPDVMTTYRVTLRADRAASPVLLSN
GNLLSQRDLPDGKHEAVWEDPFRKPSYLFALVAGKLERIEQTIVSASGKQKLLQVWVEPQDLDKTRHAMDSLVHAIRWDE
QRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAQTATDVDFANIESVVAHEYFHNWTGNRVTCRDWFQLSL
KEGLTVFRDQEFSADMMGSESGRAVKRIEDVRVLRQVQFPEDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTL
LGRDGFRKGMDLYFQRHDGQAVTCDDFRAAMADANGRDLKQFGLWYSQAGTPVVTVKTAWDGASGTLTLTLSQRCPKVGI
ETRAGMPDKQPFHIPFALGLIDAEGNDLPLQREGEPKAGASTRVLDFTQAEQTFRFINLPRGGKAPLPSLLRNFSAPVVV
DYEYSDAELTFLLSHDTDAFNRWEAGQRLATRALLHLVADVQANRELKLDPALVSAFRSVLTDGALNPAFREQALMLPAE
AYLAERMGVADPTAIHRARLFLREGLARTLKAEWLAAYEANATPGEYSPDADSMARRALRNLALGYLADSGDADMQALAD
RHYQQSDNMTDRFAALSALVNSFAPGREHALADFYERFEDDALVIDKWFSLQGMQRGEVGPHAGKRTIDTVRALMQHPAF
NLRNPNRARSLIFSFCSGNPAQFHAEDGSGYAFWADQVLALDAINPQVAARLARVMDRWQKYEMPLRERMRAALERVAAS
STLSRDVREIVSKALSA
>Mature_897_residues
MLRTDTPVTVYRKDYTPPAFAIDHVDLVLDLDPQRTVVTSTLKIQRTGTADAPLVLAGEELELVGVRLDGQPFSGVKQDG
DSLTLTGLPGTGTLEITTACNPAANTTLSGLYVSNGNFFTQCEAEGFRRITYFLDRPDVMTTYRVTLRADRAASPVLLSN
GNLLSQRDLPDGKHEAVWEDPFRKPSYLFALVAGKLERIEQTIVSASGKQKLLQVWVEPQDLDKTRHAMDSLVHAIRWDE
QRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAQTATDVDFANIESVVAHEYFHNWTGNRVTCRDWFQLSL
KEGLTVFRDQEFSADMMGSESGRAVKRIEDVRVLRQVQFPEDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTL
LGRDGFRKGMDLYFQRHDGQAVTCDDFRAAMADANGRDLKQFGLWYSQAGTPVVTVKTAWDGASGTLTLTLSQRCPKVGI
ETRAGMPDKQPFHIPFALGLIDAEGNDLPLQREGEPKAGASTRVLDFTQAEQTFRFINLPRGGKAPLPSLLRNFSAPVVV
DYEYSDAELTFLLSHDTDAFNRWEAGQRLATRALLHLVADVQANRELKLDPALVSAFRSVLTDGALNPAFREQALMLPAE
AYLAERMGVADPTAIHRARLFLREGLARTLKAEWLAAYEANATPGEYSPDADSMARRALRNLALGYLADSGDADMQALAD
RHYQQSDNMTDRFAALSALVNSFAPGREHALADFYERFEDDALVIDKWFSLQGMQRGEVGPHAGKRTIDTVRALMQHPAF
NLRNPNRARSLIFSFCSGNPAQFHAEDGSGYAFWADQVLALDAINPQVAARLARVMDRWQKYEMPLRERMRAALERVAAS
STLSRDVREIVSKALSA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI61742775, Length=343, Percent_Identity=25.9475218658892, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI61742777, Length=343, Percent_Identity=25.9475218658892, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI132814467, Length=388, Percent_Identity=25.2577319587629, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI158937236, Length=396, Percent_Identity=25.5050505050505, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI94818901, Length=463, Percent_Identity=24.622030237581, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI94818891, Length=463, Percent_Identity=24.622030237581, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI157266300, Length=376, Percent_Identity=23.936170212766, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310123622, Length=362, Percent_Identity=25.9668508287293, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI310133497, Length=365, Percent_Identity=26.3013698630137, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI194306629, Length=305, Percent_Identity=22.9508196721311, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI11641261, Length=305, Percent_Identity=22.9508196721311, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI4505029, Length=374, Percent_Identity=25.4010695187166, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI7019561, Length=233, Percent_Identity=25.7510729613734, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI194239713, Length=364, Percent_Identity=23.9010989010989, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1787163, Length=893, Percent_Identity=49.1601343784994, Blast_Score=833, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=355, Percent_Identity=29.5774647887324, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71989076, Length=355, Percent_Identity=29.5774647887324, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17569221, Length=371, Percent_Identity=25.3369272237197, Blast_Score=109, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17569225, Length=362, Percent_Identity=25.414364640884, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI133903840, Length=352, Percent_Identity=23.8636363636364, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533276, Length=309, Percent_Identity=26.8608414239482, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115533278, Length=309, Percent_Identity=26.8608414239482, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI193206928, Length=481, Percent_Identity=24.3243243243243, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193206926, Length=481, Percent_Identity=24.3243243243243, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71984353, Length=357, Percent_Identity=25.7703081232493, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71984339, Length=357, Percent_Identity=25.7703081232493, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990873, Length=320, Percent_Identity=25, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17544504, Length=359, Percent_Identity=26.4623955431755, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565628, Length=332, Percent_Identity=25, Blast_Score=71, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI9755335, Length=391, Percent_Identity=25.8312020460358, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321837, Length=341, Percent_Identity=26.6862170087977, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655257, Length=345, Percent_Identity=29.2753623188406, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24655252, Length=344, Percent_Identity=28.7790697674419, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24655274, Length=344, Percent_Identity=28.7790697674419, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24655260, Length=344, Percent_Identity=28.7790697674419, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24655265, Length=344, Percent_Identity=28.7790697674419, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24655268, Length=344, Percent_Identity=28.7790697674419, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646514, Length=378, Percent_Identity=28.042328042328, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646516, Length=341, Percent_Identity=28.7390029325513, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646518, Length=341, Percent_Identity=28.7390029325513, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24651025, Length=357, Percent_Identity=26.890756302521, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24651023, Length=357, Percent_Identity=26.890756302521, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24651021, Length=357, Percent_Identity=26.890756302521, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24646512, Length=342, Percent_Identity=26.0233918128655, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646510, Length=342, Percent_Identity=26.0233918128655, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24648786, Length=292, Percent_Identity=29.1095890410959, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651016, Length=302, Percent_Identity=25.1655629139073, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21358341, Length=272, Percent_Identity=25.3676470588235, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221379089, Length=340, Percent_Identity=26.4705882352941, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI161078673, Length=358, Percent_Identity=25.6983240223464, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650973, Length=356, Percent_Identity=26.4044943820225, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571901, Length=358, Percent_Identity=25.6983240223464, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45550850, Length=356, Percent_Identity=26.4044943820225, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648790, Length=315, Percent_Identity=25.0793650793651, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221330574, Length=362, Percent_Identity=26.5193370165746, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571792, Length=381, Percent_Identity=24.9343832020997, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550350, Length=432, Percent_Identity=23.6111111111111, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585062, Length=435, Percent_Identity=23.6781609195402, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585064, Length=435, Percent_Identity=23.6781609195402, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585066, Length=435, Percent_Identity=23.6781609195402, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99937; Mature: 99937

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTDTPVTVYRKDYTPPAFAIDHVDLVLDLDPQRTVVTSTLKIQRTGTADAPLVLAGEE
CCCCCCCEEEEECCCCCCCEEEECEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEECCC
LELVGVRLDGQPFSGVKQDGDSLTLTGLPGTGTLEITTACNPAANTTLSGLYVSNGNFFT
EEEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEEEEECCCEEE
QCEAEGFRRITYFLDRPDVMTTYRVTLRADRAASPVLLSNGNLLSQRDLPDGKHEAVWED
EECCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
PFRKPSYLFALVAGKLERIEQTIVSASGKQKLLQVWVEPQDLDKTRHAMDSLVHAIRWDE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
QRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAQTATDVDFANIESVVAHE
HHCCEEEECCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
YFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMMGSESGRAVKRIEDVRVLRQVQFP
HHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCC
EDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFQRHDGQ
CCCCCCCCCCCCCCHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCEEEEECCCC
AVTCDDFRAAMADANGRDLKQFGLWYSQAGTPVVTVKTAWDGASGTLTLTLSQRCPKVGI
EEEHHHHHHHHHCCCCCHHHHHCCHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCC
ETRAGMPDKQPFHIPFALGLIDAEGNDLPLQREGEPKAGASTRVLDFTQAEQTFRFINLP
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHEEEEECC
RGGKAPLPSLLRNFSAPVVVDYEYSDAELTFLLSHDTDAFNRWEAGQRLATRALLHLVAD
CCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VQANRELKLDPALVSAFRSVLTDGALNPAFREQALMLPAEAYLAERMGVADPTAIHRARL
HHCCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHH
FLREGLARTLKAEWLAAYEANATPGEYSPDADSMARRALRNLALGYLADSGDADMQALAD
HHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
RHYQQSDNMTDRFAALSALVNSFAPGREHALADFYERFEDDALVIDKWFSLQGMQRGEVG
HHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCC
PHAGKRTIDTVRALMQHPAFNLRNPNRARSLIFSFCSGNPAQFHAEDGSGYAFWADQVLA
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCEEE
LDAINPQVAARLARVMDRWQKYEMPLRERMRAALERVAASSTLSRDVREIVSKALSA
EECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRTDTPVTVYRKDYTPPAFAIDHVDLVLDLDPQRTVVTSTLKIQRTGTADAPLVLAGEE
CCCCCCCEEEEECCCCCCCEEEECEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEECCC
LELVGVRLDGQPFSGVKQDGDSLTLTGLPGTGTLEITTACNPAANTTLSGLYVSNGNFFT
EEEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEEEEECCCEEE
QCEAEGFRRITYFLDRPDVMTTYRVTLRADRAASPVLLSNGNLLSQRDLPDGKHEAVWED
EECCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
PFRKPSYLFALVAGKLERIEQTIVSASGKQKLLQVWVEPQDLDKTRHAMDSLVHAIRWDE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
QRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAQTATDVDFANIESVVAHE
HHCCEEEECCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
YFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMMGSESGRAVKRIEDVRVLRQVQFP
HHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCC
EDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFQRHDGQ
CCCCCCCCCCCCCCHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCEEEEECCCC
AVTCDDFRAAMADANGRDLKQFGLWYSQAGTPVVTVKTAWDGASGTLTLTLSQRCPKVGI
EEEHHHHHHHHHCCCCCHHHHHCCHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCC
ETRAGMPDKQPFHIPFALGLIDAEGNDLPLQREGEPKAGASTRVLDFTQAEQTFRFINLP
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHEEEEECC
RGGKAPLPSLLRNFSAPVVVDYEYSDAELTFLLSHDTDAFNRWEAGQRLATRALLHLVAD
CCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VQANRELKLDPALVSAFRSVLTDGALNPAFREQALMLPAEAYLAERMGVADPTAIHRARL
HHCCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHH
FLREGLARTLKAEWLAAYEANATPGEYSPDADSMARRALRNLALGYLADSGDADMQALAD
HHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
RHYQQSDNMTDRFAALSALVNSFAPGREHALADFYERFEDDALVIDKWFSLQGMQRGEVG
HHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCC
PHAGKRTIDTVRALMQHPAFNLRNPNRARSLIFSFCSGNPAQFHAEDGSGYAFWADQVLA
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCEEE
LDAINPQVAARLARVMDRWQKYEMPLRERMRAALERVAASSTLSRDVREIVSKALSA
EECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]