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The map label for this gene is cbbF3 [H]

Identifier: 94309820

GI number: 94309820

Start: 956113

End: 957129

Strand: Reverse

Name: cbbF3 [H]

Synonym: Rmet_0875

Alternate gene names: 94309820

Gene position: 957129-956113 (Counterclockwise)

Preceding gene: 94309821

Following gene: 94309816

Centisome position: 24.37

GC content: 63.13

Gene sequence:

>1017_bases
ATGACACGCATCAGCCTCACCCGCTATCTGGTCGAGGAGCAGCGCAAGCACAACACGATCGAGCCGGAACTCCGGCTGCT
GATCGAAGTGGTCGCGCGCGCCTGCAAGGCCATTTCCAACGCCGTCAGCAAGGGCGCCCTCGCGGGTGTGCTCGGCTCGG
CCGGCACCGGCAACGTTCAGGGCGAAACGCAGCAGAAGCTCGATGTGATCGCCAATGAGGTGCTGCTCGACGCCAATGAA
TGGGGTGGCCATCTGGCTGCCATGGCGTCCGAGGAAATGGACTCGTTCTACGAGATCCCGAACCGCTACCCGAAGGGCGA
ATACCTGCTGCTGTTCGATCCGCTCGACGGCTCGTCGAACATCGACGTGAACGTGTCGATCGGCACGATCTTCTCGGTCC
TGCACATGCACAAGCCCGGTCAGACCGTGACCGAGCATGACTTCATGCAGCCGGGCACCCAGCAGGTGGCAGCCGGCTAT
GCCGTGTATGGCCCGCAGACCACGCTGGTGCTGACCGTCGGCAATGGCGTGCACATGTTCACGCTGGACCGCGAGGCAGG
CAGCTTCGTGCTAACCCAGTCCGATGTGATGATCCCGGAAGACACCAAGGAATTCGCGATCAACATGTCCAACATGCGCC
ACTGGGCTCCGCCCGTGCGCCGCTACATCGACGAGTGCCTGGCCGGCGACGAAGGTCCGCGCGGCAAGAACTTCAACATG
CGCTGGATCGCCTCGATGGTGGCCGACGTGCACCGCATCCTGACACGCGGCGGCGTCTTCATGTATCCGTGGGACAAGCG
CGAGCCCGAGAAACCGGGCAAGCTGCGCCTGATGTATGAAGCCAATCCGATGGCGTTCCTGGTCGAGCAGGCGGGCGGCG
CGGCTACCAATGGCCAGCAGCGCATTCTGGACGTGGAGCCGACCAAGCTCCACCAGCGCGTATCGGTCATCCTCGGTTCG
AAGAATGAAGTCGAGCGCGTCACGCGGTATCACCAGGAAGACGCCGCCAAGGCGTAA

Upstream 100 bases:

>100_bases
GCGCGAGATCGTCAGCAAGGCCCTGTCGGCCTGACCCGGAAAGTGGCATGTCCGCAGCGGCACACATGTAGAATTGCGGC
CATCCAAGGAGAACCCCACC

Downstream 100 bases:

>100_bases
CGGGTAGATCCGGTTTCGACAAGCACAGGGCGCCTCGGCGCCCTGTCTGCTTTGCTGAAGCCAACAGCCGCACGGCAATC
CGTAAAAAAGCGGCAGGCTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTRISLTRYLVEEQRKHNTIEPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQGETQQKLDVIANEVLLDANE
WGGHLAAMASEEMDSFYEIPNRYPKGEYLLLFDPLDGSSNIDVNVSIGTIFSVLHMHKPGQTVTEHDFMQPGTQQVAAGY
AVYGPQTTLVLTVGNGVHMFTLDREAGSFVLTQSDVMIPEDTKEFAINMSNMRHWAPPVRRYIDECLAGDEGPRGKNFNM
RWIASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAFLVEQAGGAATNGQQRILDVEPTKLHQRVSVILGS
KNEVERVTRYHQEDAAKA

Sequences:

>Translated_338_residues
MTRISLTRYLVEEQRKHNTIEPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQGETQQKLDVIANEVLLDANE
WGGHLAAMASEEMDSFYEIPNRYPKGEYLLLFDPLDGSSNIDVNVSIGTIFSVLHMHKPGQTVTEHDFMQPGTQQVAAGY
AVYGPQTTLVLTVGNGVHMFTLDREAGSFVLTQSDVMIPEDTKEFAINMSNMRHWAPPVRRYIDECLAGDEGPRGKNFNM
RWIASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAFLVEQAGGAATNGQQRILDVEPTKLHQRVSVILGS
KNEVERVTRYHQEDAAKA
>Mature_337_residues
TRISLTRYLVEEQRKHNTIEPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQGETQQKLDVIANEVLLDANEW
GGHLAAMASEEMDSFYEIPNRYPKGEYLLLFDPLDGSSNIDVNVSIGTIFSVLHMHKPGQTVTEHDFMQPGTQQVAAGYA
VYGPQTTLVLTVGNGVHMFTLDREAGSFVLTQSDVMIPEDTKEFAINMSNMRHWAPPVRRYIDECLAGDEGPRGKNFNMR
WIASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAFLVEQAGGAATNGQQRILDVEPTKLHQRVSVILGSK
NEVERVTRYHQEDAAKA

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=335, Percent_Identity=42.3880597014925, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI16579888, Length=335, Percent_Identity=42.3880597014925, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI22907028, Length=334, Percent_Identity=40.4191616766467, Blast_Score=235, Evalue=5e-62,
Organism=Escherichia coli, GI1790679, Length=330, Percent_Identity=45.7575757575758, Blast_Score=281, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17508131, Length=327, Percent_Identity=44.0366972477064, Blast_Score=272, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323409, Length=324, Percent_Identity=39.5061728395062, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI45550998, Length=327, Percent_Identity=43.7308868501529, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI19921562, Length=327, Percent_Identity=43.7308868501529, Blast_Score=257, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37526; Mature: 37395

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRISLTRYLVEEQRKHNTIEPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQ
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GETQQKLDVIANEVLLDANEWGGHLAAMASEEMDSFYEIPNRYPKGEYLLLFDPLDGSSN
CCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
IDVNVSIGTIFSVLHMHKPGQTVTEHDFMQPGTQQVAAGYAVYGPQTTLVLTVGNGVHMF
EEEEEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHCCEEEECCCEEEEEEECCCEEEE
TLDREAGSFVLTQSDVMIPEDTKEFAINMSNMRHWAPPVRRYIDECLAGDEGPRGKNFNM
EEECCCCCEEEEECCEECCCCCHHHHEEHHHCHHCCCHHHHHHHHHHCCCCCCCCCCCCH
RWIASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAFLVEQAGGAATNGQQ
HHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCC
RILDVEPTKLHQRVSVILGSKNEVERVTRYHQEDAAKA
EEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRISLTRYLVEEQRKHNTIEPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQ
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GETQQKLDVIANEVLLDANEWGGHLAAMASEEMDSFYEIPNRYPKGEYLLLFDPLDGSSN
CCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
IDVNVSIGTIFSVLHMHKPGQTVTEHDFMQPGTQQVAAGYAVYGPQTTLVLTVGNGVHMF
EEEEEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHCCEEEECCCEEEEEEECCCEEEE
TLDREAGSFVLTQSDVMIPEDTKEFAINMSNMRHWAPPVRRYIDECLAGDEGPRGKNFNM
EEECCCCCEEEEECCEECCCCCHHHHEEHHHCHHCCCHHHHHHHHHHCCCCCCCCCCCCH
RWIASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAFLVEQAGGAATNGQQ
HHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCC
RILDVEPTKLHQRVSVILGSKNEVERVTRYHQEDAAKA
EEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA