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The map label for this gene is gntR [H]

Identifier: 94309813

GI number: 94309813

Start: 947557

End: 949377

Strand: Reverse

Name: gntR [H]

Synonym: Rmet_0868

Alternate gene names: 94309813

Gene position: 949377-947557 (Counterclockwise)

Preceding gene: 94309816

Following gene: 94309812

Centisome position: 24.17

GC content: 66.28

Gene sequence:

>1821_bases
ATGCACCCGCCCTCGACGTGCACGATCGTGCCGGCTGGCAGGTGCTCGAAAAAGCACTGGCCGGCAGCCAGCCGGATGGT
GCGGGAAACGGGTCCGGGAAATTCGGTCGGTTCGGTCGGTTCGGCGGGCTTGATGAATGACATGGCGTGGCTCCTGGGTC
GCAAAATCATGCAAACAAGGCTACCGAGCCGCCCGCCTTGCCAACAGGCACAAGCCATCGCAAGCGCAACCAGAACAGAT
GTCAAACTTGCGCCCTGTTACGATACAGAGACACCGCATCTGTATCTGTTCCACTTCACCCCATCGCGCGAAGATGCCCC
CATGAACGCCAACCTCGCCGCCAACCTCGCCGCCAACCTCGCCGCCAGCCCTGCCCCCGCCGCATCGCCTCAATCCTCCG
CCCCGCTCTACCAGCAGGTGGCTGGCCATTATCGGCAGGCGATTTCGGTGGGCACGCTGGCGCCGGGTGACCGGATGCCG
TCCGTGCGTTCGCTGATGGGGCTGCACGACGTGAGCCTGTCCACGGCGCTCCAGGCCTGCCGCGAGCTTGAGGCGGCCGG
CCTGCTCGAAGCGCGGCCGCGCTCGGGCTATTTCGTGCGTGCTCCTGCGCGGCCCTCGCTGGCCCCGATCGAAGAACCGG
CCACCGGATTGCCGGATCCCGCGCAGTACGTCGGCATCCACCAGCGCATCTCCGCAATCCTGGCGCGCGGCCAGCATTAC
CGGATCAACTTCGGCGGTGCCTGCGGGGCGCCGGAGCTGTATCCGGCGGCCGCATTGCGCAATGCCGCCACGCGGGCACT
GCGGCGATACCCAATGCTCTTTGGCAGTTCGGTCGACTTCGACGGCCACCCCGCGTTTCGCGCGGCATTGGCCAGGCACG
CGTTGCGCGCGCGGATCAACGTCGCGCCCGAGGACATCGTGGTCACACACGGCTGCACCGAAGCGCTGACGCTGGCCCTG
CGGGCCGTGGCGAACCCGGGCGATGTCATCGCCGTGGAATCACCGACGTACTACGGCCTGCTGCAGATTCTCGAAAGCCT
GGGAATGCGTGCGCTCGAGATTCCTTGCAGCCCGCAGACCGGCATGTCGCTCGAAGCGCTGGATCTGGCTGCCCAGACCT
ACGACAACATCAAGGCCGTCTGCGTGGTGCCGAACCTGCAGAATCCGCTCGGCTGCGTCATGCCGGACACGCACAAACAG
CGCTTGGTGAACTGGTGCGCCACACGCGGTCTCACGCTGATCGAAGACGACTGCTGCTCGGCCACCTTCGACGACGAAGT
GCCGCTGACGGCCGCCAAGGCATGGGACACCACGGGCTCCGTGATCTACTGCGGGTCGCTCCATAAGATCCTGGCGCCCG
GAATGCGGCTCGGCTGGATCACGGCGGGCAAGTGGCAGGCGCGCGTGGAGATGCTCAAGTTCGGCCTGTCGCGCCCGAAC
GAGATGCTGACGCAGATCGCCGTGGCCGAGTTCATGGGCACGGGGGCATTCGAGCGTCACCTGCGTCGCCTGCGCACCCA
GTTGCGAACCCAGCGCGAATGGATGGCCCAGAGAATCGCGACCACCTTCCCGTCAGGCACCCGCCTGACGCTGCCGCGCG
GTGGGCTGCATCTCTGGGTGGAAATGCCCCAGTCGATCTCGTCGGAAGCGGTCTTCGAACAGGCGCTGGCCGAGGGCATC
CGGGTGATGCCGGGCGCCATGTTCTCGAACTCGAATCGCTTCAATCACTACCTGCGGCTGAACTGCGGCATTCCTCGATC
TCCGGAAATCGAGCGCGCGCTCGATACCGTGGCGGGCGTGGTTCGGCGCATGGCCGCCTGA

Upstream 100 bases:

>100_bases
CCAACCTGTGACTTGGATCACTTGCACGCCCCCGGAATGCAGCGTGTACGCGGCCTGGCCGATATCGCTGGCCAGCCAGC
ACGGCGCGGTGGTCACGACA

Downstream 100 bases:

>100_bases
ACGTGGCGCCGATGCCAACGCCAGCATCGTTCTTGCGAGATTTCTTCCCCGATTCGGGCACGCTCGCCTATCCTATTGCG
CGATACGCCGAACACAAAAA

Product: regulatory protein GntR, HTH:Aminotransferase, class I and II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MHPPSTCTIVPAGRCSKKHWPAASRMVRETGPGNSVGSVGSAGLMNDMAWLLGRKIMQTRLPSRPPCQQAQAIASATRTD
VKLAPCYDTETPHLYLFHFTPSREDAPMNANLAANLAANLAASPAPAASPQSSAPLYQQVAGHYRQAISVGTLAPGDRMP
SVRSLMGLHDVSLSTALQACRELEAAGLLEARPRSGYFVRAPARPSLAPIEEPATGLPDPAQYVGIHQRISAILARGQHY
RINFGGACGAPELYPAAALRNAATRALRRYPMLFGSSVDFDGHPAFRAALARHALRARINVAPEDIVVTHGCTEALTLAL
RAVANPGDVIAVESPTYYGLLQILESLGMRALEIPCSPQTGMSLEALDLAAQTYDNIKAVCVVPNLQNPLGCVMPDTHKQ
RLVNWCATRGLTLIEDDCCSATFDDEVPLTAAKAWDTTGSVIYCGSLHKILAPGMRLGWITAGKWQARVEMLKFGLSRPN
EMLTQIAVAEFMGTGAFERHLRRLRTQLRTQREWMAQRIATTFPSGTRLTLPRGGLHLWVEMPQSISSEAVFEQALAEGI
RVMPGAMFSNSNRFNHYLRLNCGIPRSPEIERALDTVAGVVRRMAA

Sequences:

>Translated_606_residues
MHPPSTCTIVPAGRCSKKHWPAASRMVRETGPGNSVGSVGSAGLMNDMAWLLGRKIMQTRLPSRPPCQQAQAIASATRTD
VKLAPCYDTETPHLYLFHFTPSREDAPMNANLAANLAANLAASPAPAASPQSSAPLYQQVAGHYRQAISVGTLAPGDRMP
SVRSLMGLHDVSLSTALQACRELEAAGLLEARPRSGYFVRAPARPSLAPIEEPATGLPDPAQYVGIHQRISAILARGQHY
RINFGGACGAPELYPAAALRNAATRALRRYPMLFGSSVDFDGHPAFRAALARHALRARINVAPEDIVVTHGCTEALTLAL
RAVANPGDVIAVESPTYYGLLQILESLGMRALEIPCSPQTGMSLEALDLAAQTYDNIKAVCVVPNLQNPLGCVMPDTHKQ
RLVNWCATRGLTLIEDDCCSATFDDEVPLTAAKAWDTTGSVIYCGSLHKILAPGMRLGWITAGKWQARVEMLKFGLSRPN
EMLTQIAVAEFMGTGAFERHLRRLRTQLRTQREWMAQRIATTFPSGTRLTLPRGGLHLWVEMPQSISSEAVFEQALAEGI
RVMPGAMFSNSNRFNHYLRLNCGIPRSPEIERALDTVAGVVRRMAA
>Mature_606_residues
MHPPSTCTIVPAGRCSKKHWPAASRMVRETGPGNSVGSVGSAGLMNDMAWLLGRKIMQTRLPSRPPCQQAQAIASATRTD
VKLAPCYDTETPHLYLFHFTPSREDAPMNANLAANLAANLAASPAPAASPQSSAPLYQQVAGHYRQAISVGTLAPGDRMP
SVRSLMGLHDVSLSTALQACRELEAAGLLEARPRSGYFVRAPARPSLAPIEEPATGLPDPAQYVGIHQRISAILARGQHY
RINFGGACGAPELYPAAALRNAATRALRRYPMLFGSSVDFDGHPAFRAALARHALRARINVAPEDIVVTHGCTEALTLAL
RAVANPGDVIAVESPTYYGLLQILESLGMRALEIPCSPQTGMSLEALDLAAQTYDNIKAVCVVPNLQNPLGCVMPDTHKQ
RLVNWCATRGLTLIEDDCCSATFDDEVPLTAAKAWDTTGSVIYCGSLHKILAPGMRLGWITAGKWQARVEMLKFGLSRPN
EMLTQIAVAEFMGTGAFERHLRRLRTQLRTQREWMAQRIATTFPSGTRLTLPRGGLHLWVEMPQSISSEAVFEQALAEGI
RVMPGAMFSNSNRFNHYLRLNCGIPRSPEIERALDTVAGVVRRMAA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=412, Percent_Identity=21.8446601941748, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI33469970, Length=412, Percent_Identity=21.8446601941748, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4507369, Length=160, Percent_Identity=28.75, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1790797, Length=471, Percent_Identity=33.3333333333333, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1787710, Length=475, Percent_Identity=33.0526315789474, Blast_Score=247, Evalue=1e-66,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 65633; Mature: 65633

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPPSTCTIVPAGRCSKKHWPAASRMVRETGPGNSVGSVGSAGLMNDMAWLLGRKIMQTR
CCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
LPSRPPCQQAQAIASATRTDVKLAPCYDTETPHLYLFHFTPSREDAPMNANLAANLAANL
CCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
AASPAPAASPQSSAPLYQQVAGHYRQAISVGTLAPGDRMPSVRSLMGLHDVSLSTALQAC
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RELEAAGLLEARPRSGYFVRAPARPSLAPIEEPATGLPDPAQYVGIHQRISAILARGQHY
HHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
RINFGGACGAPELYPAAALRNAATRALRRYPMLFGSSVDFDGHPAFRAALARHALRARIN
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
VAPEDIVVTHGCTEALTLALRAVANPGDVIAVESPTYYGLLQILESLGMRALEIPCSPQT
CCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCEEEECCCCCCC
GMSLEALDLAAQTYDNIKAVCVVPNLQNPLGCVMPDTHKQRLVNWCATRGLTLIEDDCCS
CCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCC
ATFDDEVPLTAAKAWDTTGSVIYCGSLHKILAPGMRLGWITAGKWQARVEMLKFGLSRPN
CCCCCCCCCEEHHCCCCCCCEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHH
EMLTQIAVAEFMGTGAFERHLRRLRTQLRTQREWMAQRIATTFPSGTRLTLPRGGLHLWV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEE
EMPQSISSEAVFEQALAEGIRVMPGAMFSNSNRFNHYLRLNCGIPRSPEIERALDTVAGV
ECCHHCCHHHHHHHHHHCCHHCCCCHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
VRRMAA
HHHHCC
>Mature Secondary Structure
MHPPSTCTIVPAGRCSKKHWPAASRMVRETGPGNSVGSVGSAGLMNDMAWLLGRKIMQTR
CCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
LPSRPPCQQAQAIASATRTDVKLAPCYDTETPHLYLFHFTPSREDAPMNANLAANLAANL
CCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
AASPAPAASPQSSAPLYQQVAGHYRQAISVGTLAPGDRMPSVRSLMGLHDVSLSTALQAC
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RELEAAGLLEARPRSGYFVRAPARPSLAPIEEPATGLPDPAQYVGIHQRISAILARGQHY
HHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
RINFGGACGAPELYPAAALRNAATRALRRYPMLFGSSVDFDGHPAFRAALARHALRARIN
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
VAPEDIVVTHGCTEALTLALRAVANPGDVIAVESPTYYGLLQILESLGMRALEIPCSPQT
CCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCEEEECCCCCCC
GMSLEALDLAAQTYDNIKAVCVVPNLQNPLGCVMPDTHKQRLVNWCATRGLTLIEDDCCS
CCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCC
ATFDDEVPLTAAKAWDTTGSVIYCGSLHKILAPGMRLGWITAGKWQARVEMLKFGLSRPN
CCCCCCCCCEEHHCCCCCCCEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHH
EMLTQIAVAEFMGTGAFERHLRRLRTQLRTQREWMAQRIATTFPSGTRLTLPRGGLHLWV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEE
EMPQSISSEAVFEQALAEGIRVMPGAMFSNSNRFNHYLRLNCGIPRSPEIERALDTVAGV
ECCHHCCHHHHHHHHHHCCHHCCCCHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
VRRMAA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]