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The map label for this gene is soxR [H]

Identifier: 94309769

GI number: 94309769

Start: 897729

End: 898613

Strand: Direct

Name: soxR [H]

Synonym: Rmet_0824

Alternate gene names: 94309769

Gene position: 897729-898613 (Clockwise)

Preceding gene: 94309764

Following gene: 94309772

Centisome position: 22.85

GC content: 68.02

Gene sequence:

>885_bases
ATGAGCACAATCCGCTTTCTAAGGACCTTCGTAGCCGTGGCCGAGCATGGCTCGTTCGCCGCTGCCGCCGGTCAGGTGGC
GCTGACCCAGGCGGCAGTGAGCCTGCAGATGCGCTCCCTGGAGGAGGAATTGCGGCGCGAACTGTTCGATCGCAGCGGGC
GCGTGGCAGTGCTCAATGCCGATGGCCGGGAATTGCTGCCCATGGCGCGGCGGCTGCTGGATCTCTATGAGGAGATGCGG
CTGCCACTTTCAGGGTCCGATGCGATGGCGGGGGCTGTGGCGGTCGGCGCGGTGGTGTCGGTGATGGGGGGGCTGTCGCA
TGTTGTGGCGCGGCTCAAGCGCACGCACGCGGCGCTTGATGTCCGGCTTATCGGCGCGAAGTCGATCGAACTGGCGACGA
TGGTGGAGGGCGGCGAGCTCGATGCGGCGTTTCTGGTCGAAGGCATGGCGCGCCCATCCGGGGTGCTGCGCTGGACGCCC
CTCTATGACGAGCCGCTGGTGGCCATCGCCTCGCGGGGCAGCGACGGCGATACGGCGCGTCAGGCGCTGGCGGCCAACCC
GTTCCTGCGGTTCGATCGCACCCAGCGTACTGGCGTGCTGGTGGAGCGCGCGCTCCGCCGCGCGCATCTGCGCACCAACG
AGTTTCTCGAACTGAATTCGATCGAGGCCTTGGTGGAACTCGTGCGTCAGGAGGTGGGGGTGACCGTGGTGCCGCTGCTA
AAACGTGCCCGCTGGCAGGAAGACGAGGCGCTGCGCATCCTGCCGTTGCAGGCCGATGGCGAGCCAATGGTCCGCACCAT
CGGCATGCTGGAGCGGCGCGATCACGGCCGCGCGCACGTGACCGAGGCGATCCGCGCTGCGTGTGCCGAGTTGTTCGCGG
CCTGA

Upstream 100 bases:

>100_bases
GTCGACATAATGAAAGTTAATATTCCTTGCCTGATCCACAAGAAAAACTTGTGAATCGAGCAAGGAGGCCAGCGACCCAT
ATGCATTCAATGAGCACCCC

Downstream 100 bases:

>100_bases
ACGTCGCCTGAATTCCCCCTGAACGCCGCATTGCTGCGGTGCCGGAATGAAAAAAGGGCGCCGCAATGGGCGCCCTTCCT
TTACAGCGGAAGCTGAGACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSTIRFLRTFVAVAEHGSFAAAAGQVALTQAAVSLQMRSLEEELRRELFDRSGRVAVLNADGRELLPMARRLLDLYEEMR
LPLSGSDAMAGAVAVGAVVSVMGGLSHVVARLKRTHAALDVRLIGAKSIELATMVEGGELDAAFLVEGMARPSGVLRWTP
LYDEPLVAIASRGSDGDTARQALAANPFLRFDRTQRTGVLVERALRRAHLRTNEFLELNSIEALVELVRQEVGVTVVPLL
KRARWQEDEALRILPLQADGEPMVRTIGMLERRDHGRAHVTEAIRAACAELFAA

Sequences:

>Translated_294_residues
MSTIRFLRTFVAVAEHGSFAAAAGQVALTQAAVSLQMRSLEEELRRELFDRSGRVAVLNADGRELLPMARRLLDLYEEMR
LPLSGSDAMAGAVAVGAVVSVMGGLSHVVARLKRTHAALDVRLIGAKSIELATMVEGGELDAAFLVEGMARPSGVLRWTP
LYDEPLVAIASRGSDGDTARQALAANPFLRFDRTQRTGVLVERALRRAHLRTNEFLELNSIEALVELVRQEVGVTVVPLL
KRARWQEDEALRILPLQADGEPMVRTIGMLERRDHGRAHVTEAIRAACAELFAA
>Mature_293_residues
STIRFLRTFVAVAEHGSFAAAAGQVALTQAAVSLQMRSLEEELRRELFDRSGRVAVLNADGRELLPMARRLLDLYEEMRL
PLSGSDAMAGAVAVGAVVSVMGGLSHVVARLKRTHAALDVRLIGAKSIELATMVEGGELDAAFLVEGMARPSGVLRWTPL
YDEPLVAIASRGSDGDTARQALAANPFLRFDRTQRTGVLVERALRRAHLRTNEFLELNSIEALVELVRQEVGVTVVPLLK
RARWQEDEALRILPLQADGEPMVRTIGMLERRDHGRAHVTEAIRAACAELFAA

Specific function: Transcriptional repressor of soxA gene expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=277, Percent_Identity=24.9097472924188, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=29.0657439446367, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=282, Percent_Identity=28.0141843971631, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788626, Length=154, Percent_Identity=38.3116883116883, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=310, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32121; Mature: 31989

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIRFLRTFVAVAEHGSFAAAAGQVALTQAAVSLQMRSLEEELRRELFDRSGRVAVLNA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGRELLPMARRLLDLYEEMRLPLSGSDAMAGAVAVGAVVSVMGGLSHVVARLKRTHAALD
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VRLIGAKSIELATMVEGGELDAAFLVEGMARPSGVLRWTPLYDEPLVAIASRGSDGDTAR
EEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCHHHHCCCCCCCHHHH
QALAANPFLRFDRTQRTGVLVERALRRAHLRTNEFLELNSIEALVELVRQEVGVTVVPLL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHH
KRARWQEDEALRILPLQADGEPMVRTIGMLERRDHGRAHVTEAIRAACAELFAA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STIRFLRTFVAVAEHGSFAAAAGQVALTQAAVSLQMRSLEEELRRELFDRSGRVAVLNA
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGRELLPMARRLLDLYEEMRLPLSGSDAMAGAVAVGAVVSVMGGLSHVVARLKRTHAALD
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VRLIGAKSIELATMVEGGELDAAFLVEGMARPSGVLRWTPLYDEPLVAIASRGSDGDTAR
EEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCHHHHCCCCCCCHHHH
QALAANPFLRFDRTQRTGVLVERALRRAHLRTNEFLELNSIEALVELVRQEVGVTVVPLL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHH
KRARWQEDEALRILPLQADGEPMVRTIGMLERRDHGRAHVTEAIRAACAELFAA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA