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The map label for this gene is yjjL [H]

Identifier: 94309721

GI number: 94309721

Start: 852103

End: 853446

Strand: Direct

Name: yjjL [H]

Synonym: Rmet_0776

Alternate gene names: 94309721

Gene position: 852103-853446 (Clockwise)

Preceding gene: 94309715

Following gene: 94309722

Centisome position: 21.69

GC content: 65.25

Gene sequence:

>1344_bases
ATGCACCATCTTTCCGCCGACACGCAGCAGGCCAACAACAACGACTATCTGGTCAGCAAATCACGCGCATGGTTTGCGTT
TGCCATGACCTTCGCGCTGATGCTCTTCGACTACATCGATCGTCAGGTGATCGTGTCCTTGTTTCCGCACCTGAAGGCCG
AGTGGAACCTTTCCGACAAGCAACTGGGCGCGCTGGTGTCGATCATCTCGGTGGTGGTCGCGCTGGGCGGCATCCCCGTT
GCGCTGTTGGCGGACCGCGTCAGCCGCGTCAAGAGCGTGGTGGTCATGGGCGTGGTCTGGAGCCTGGCCACGATTTCCTG
CATGTTTACCCGCAACTACTCGCAGTTGTTCATGGCGCGCGCGATGGTGGGTGTGGGTGAGTCCGGCTACGGCTCCGTCG
GTGCGGCGCTGATCGCCAGCCTGTTCCCGGCAAGGTTGCGTTCGATGCTGCTCGGCGCGTTCTTCGCGGCCGGATCGATT
GGCGCGGTGCTCGGCGTGGTGCTGGGTGGCGTGATTACCGCACGCTGGGGCTGGCAGGCCGCGTTCGGCGTGGTGGGTGT
GCCCGGCCTGCTGCTGGCGCTGCTCTACATGTTCGTGCCGGACTACAAGACTGCGGCGCTGGACACGCGGCCGGCCCATG
AGCAAGGGCAAGCAAAGGGCCTGCTCGCGCACATGGTGTCGGCGCTGACGAGCTCGCGCACGCTGTGGTGGACCTGCCTG
GGTGCGGCGCTGCAGCTTGTCGTGGTATCGACGATCTGGGCCTGGCTGCCGAGCTACTTCAATCGCCTCCACGGCACGCC
GGTGGATCAGGCTGCCATGCAGTCGGCGTTGATCGTGCTGTGCGGCGCGGTGGGTTGCTTCGTCTGGGGCATTGTTGCGG
ATGTCGCCGGCACCAAGCAGCCGCGCAACAAGCTCAAGACGGTGTCGTTCCTGTGCATGGTGACCGCGCCGATCCTGGTG
GTTGCATTCAGCGCCGCGGAGTCCATGAACCAGCAGTTCCTGCTGATCGCGCTGGGTGGCTTCCTGATGACATGCACGGT
TGGGCCGGCTTCGAGCGTGGTGCTCGACGTGGTGCATCCGGGGCTGCGCTCCACCGGCGCTGCGCTGCTGTCGCTGTTCC
AGAACCTGTTCGGACTCGCCATCGGTCCGTTCGTAGGCGGTGCGCTCTCCGACGCATTCGGCCTGCAAGCGGCATTGACG
GCAATGCCGGTCTTTGGCCTGCTCGCGGCGCTGTGCCTGCTGCGCGCATCGCGCACCTATGAGCGCGATCTGCAGGAGGT
GGCGCAGATCCAGTCCGCCATCGCCGAACAACCCGCCGGGGCCGCGGCTTCGATGACAGCGTGA

Upstream 100 bases:

>100_bases
CGCACCGCCGGATTCTGGAGGGAAAAACGGCGGGCTTCCGATAGAAAACCAGGCAGTTGTGACAGGGCCCGACAGCCGGC
CTGCACAGGAGACACCGCTC

Downstream 100 bases:

>100_bases
TGAGTGAAGTGGATGTGCCTGGGGCAGTCGTAGCAGCGGGCGCGGAAGCGGGCCCCAGGCGCCCCAGCGTCGGCAGCATG
GCGGCACTGACCGCTGGCTT

Product: putative major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MHHLSADTQQANNNDYLVSKSRAWFAFAMTFALMLFDYIDRQVIVSLFPHLKAEWNLSDKQLGALVSIISVVVALGGIPV
ALLADRVSRVKSVVVMGVVWSLATISCMFTRNYSQLFMARAMVGVGESGYGSVGAALIASLFPARLRSMLLGAFFAAGSI
GAVLGVVLGGVITARWGWQAAFGVVGVPGLLLALLYMFVPDYKTAALDTRPAHEQGQAKGLLAHMVSALTSSRTLWWTCL
GAALQLVVVSTIWAWLPSYFNRLHGTPVDQAAMQSALIVLCGAVGCFVWGIVADVAGTKQPRNKLKTVSFLCMVTAPILV
VAFSAAESMNQQFLLIALGGFLMTCTVGPASSVVLDVVHPGLRSTGAALLSLFQNLFGLAIGPFVGGALSDAFGLQAALT
AMPVFGLLAALCLLRASRTYERDLQEVAQIQSAIAEQPAGAAASMTA

Sequences:

>Translated_447_residues
MHHLSADTQQANNNDYLVSKSRAWFAFAMTFALMLFDYIDRQVIVSLFPHLKAEWNLSDKQLGALVSIISVVVALGGIPV
ALLADRVSRVKSVVVMGVVWSLATISCMFTRNYSQLFMARAMVGVGESGYGSVGAALIASLFPARLRSMLLGAFFAAGSI
GAVLGVVLGGVITARWGWQAAFGVVGVPGLLLALLYMFVPDYKTAALDTRPAHEQGQAKGLLAHMVSALTSSRTLWWTCL
GAALQLVVVSTIWAWLPSYFNRLHGTPVDQAAMQSALIVLCGAVGCFVWGIVADVAGTKQPRNKLKTVSFLCMVTAPILV
VAFSAAESMNQQFLLIALGGFLMTCTVGPASSVVLDVVHPGLRSTGAALLSLFQNLFGLAIGPFVGGALSDAFGLQAALT
AMPVFGLLAALCLLRASRTYERDLQEVAQIQSAIAEQPAGAAASMTA
>Mature_447_residues
MHHLSADTQQANNNDYLVSKSRAWFAFAMTFALMLFDYIDRQVIVSLFPHLKAEWNLSDKQLGALVSIISVVVALGGIPV
ALLADRVSRVKSVVVMGVVWSLATISCMFTRNYSQLFMARAMVGVGESGYGSVGAALIASLFPARLRSMLLGAFFAAGSI
GAVLGVVLGGVITARWGWQAAFGVVGVPGLLLALLYMFVPDYKTAALDTRPAHEQGQAKGLLAHMVSALTSSRTLWWTCL
GAALQLVVVSTIWAWLPSYFNRLHGTPVDQAAMQSALIVLCGAVGCFVWGIVADVAGTKQPRNKLKTVSFLCMVTAPILV
VAFSAAESMNQQFLLIALGGFLMTCTVGPASSVVLDVVHPGLRSTGAALLSLFQNLFGLAIGPFVGGALSDAFGLQAALT
AMPVFGLLAALCLLRASRTYERDLQEVAQIQSAIAEQPAGAAASMTA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=378, Percent_Identity=25.1322751322751, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194239645, Length=387, Percent_Identity=25.3229974160207, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI215490096, Length=400, Percent_Identity=26, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI14042968, Length=400, Percent_Identity=26, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI215490102, Length=380, Percent_Identity=23.4210526315789, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI215490100, Length=376, Percent_Identity=25.531914893617, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI2367379, Length=333, Percent_Identity=26.7267267267267, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082231, Length=253, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789515, Length=286, Percent_Identity=24.4755244755245, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=396, Percent_Identity=26.5151515151515, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193209775, Length=407, Percent_Identity=23.3415233415233, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71992409, Length=451, Percent_Identity=24.8337028824834, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17539092, Length=415, Percent_Identity=25.7831325301205, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24654039, Length=384, Percent_Identity=22.65625, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17864456, Length=384, Percent_Identity=22.65625, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24654041, Length=394, Percent_Identity=22.0812182741117, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654037, Length=394, Percent_Identity=22.0812182741117, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654044, Length=181, Percent_Identity=24.8618784530387, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47192; Mature: 47192

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]