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The map label for this gene is 94309678

Identifier: 94309678

GI number: 94309678

Start: 811003

End: 811926

Strand: Direct

Name: 94309678

Synonym: Rmet_0733

Alternate gene names: NA

Gene position: 811003-811926 (Clockwise)

Preceding gene: 94309676

Following gene: 94309679

Centisome position: 20.65

GC content: 63.96

Gene sequence:

>924_bases
ATGTCAACGGGCTACTACACGCATCCGTCGTTCCTGATGCATGAGATGGGGCATTTCCATCCTGAATGCCCGGAACGCCT
GCAGGCTATCGAGGACCATCTGATTTCGCACGGGATGGATGGCCTGCTGGACCGGCGGGAGGCGCCGGCTGCCACCGACG
CGCAGATCGAGCGCGTGCATCGGCCCGAATATGTGGCCAGCCTTGTCGCGATGAGTCCCGCCACCGGCTACCACCCGATC
GATCCCGATACCCTGATGAACCCGCACACGCTCACCGCTGCCAGGCATGCGGCTGGTGCGGCGGTGGCTGCCACGGACGC
CGTCATTGCCGGCGAACTGGAGAACGCGTTCTGCTGCGCGCGTCCGCCGGGCCATCATGCCGAGCCCGATCGCGCGATGG
GATTCTGTTTCTTCGATAACGTGGCGATTGCGGCACGACATGCGCTCACGGCGCACGGCCTGTCGCGCGTGGCGATCGTC
GATTTCGATGTGCACCACGGCAACGGCACCGAGGCGGCCTTCCGCGACGACCCGCAGGTGCTGATGTGCAGCTTTTTCCA
GCACCCGTTCTACCCGTACAGCGGCACGGAGCACTTTGCGCCGAACATGTCGAACATCCCGCTGCCCGCGTACTCCAACG
GCCTGGCTGTGCGCGAGGTCGTGGAAACGATCTGGCTGCCGCGGCTCAACGAATTCAAGCCCGAGATGCTGTTTATCTCC
GCCGGCTTCGATGCGCATCGCGAGGATGACCTCGGACAGATGGGACTGGTCGAGCAGGACTATGCGTGGATCACGCAGCA
GCTCGTCGATGTGGCGCGGGCTCATGCGAAGGGCCGCATCGTGAGTTGTCTGGAGGGGGGGTACAACCTTAGTGCCCTGG
CGCGAAGCGTATTTGCCCACCTGAAGGTGCTGGTCGAGACCTGA

Upstream 100 bases:

>100_bases
TACTTCGGTGCGCCGTACACGACAGCCAACAGGCGTAGAAGCGCGGGGCACGTCATGTGCTAACGTAGCGTCTGGAGACG
AACTTGACCCATAACGAATA

Downstream 100 bases:

>100_bases
AAGTGACAAAAACGCCGCTTATAAGGGCGTCTATATGACGCCAGCGCATAAAGCCATCGAAAAAATCTCGTTTGAGGTAT
GAAGCGGATCGCATAAAATG

Product: Deacetylase, histone deacetylase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSTGYYTHPSFLMHEMGHFHPECPERLQAIEDHLISHGMDGLLDRREAPAATDAQIERVHRPEYVASLVAMSPATGYHPI
DPDTLMNPHTLTAARHAAGAAVAATDAVIAGELENAFCCARPPGHHAEPDRAMGFCFFDNVAIAARHALTAHGLSRVAIV
DFDVHHGNGTEAAFRDDPQVLMCSFFQHPFYPYSGTEHFAPNMSNIPLPAYSNGLAVREVVETIWLPRLNEFKPEMLFIS
AGFDAHREDDLGQMGLVEQDYAWITQQLVDVARAHAKGRIVSCLEGGYNLSALARSVFAHLKVLVET

Sequences:

>Translated_307_residues
MSTGYYTHPSFLMHEMGHFHPECPERLQAIEDHLISHGMDGLLDRREAPAATDAQIERVHRPEYVASLVAMSPATGYHPI
DPDTLMNPHTLTAARHAAGAAVAATDAVIAGELENAFCCARPPGHHAEPDRAMGFCFFDNVAIAARHALTAHGLSRVAIV
DFDVHHGNGTEAAFRDDPQVLMCSFFQHPFYPYSGTEHFAPNMSNIPLPAYSNGLAVREVVETIWLPRLNEFKPEMLFIS
AGFDAHREDDLGQMGLVEQDYAWITQQLVDVARAHAKGRIVSCLEGGYNLSALARSVFAHLKVLVET
>Mature_306_residues
STGYYTHPSFLMHEMGHFHPECPERLQAIEDHLISHGMDGLLDRREAPAATDAQIERVHRPEYVASLVAMSPATGYHPID
PDTLMNPHTLTAARHAAGAAVAATDAVIAGELENAFCCARPPGHHAEPDRAMGFCFFDNVAIAARHALTAHGLSRVAIVD
FDVHHGNGTEAAFRDDPQVLMCSFFQHPFYPYSGTEHFAPNMSNIPLPAYSNGLAVREVVETIWLPRLNEFKPEMLFISA
GFDAHREDDLGQMGLVEQDYAWITQQLVDVARAHAKGRIVSCLEGGYNLSALARSVFAHLKVLVET

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=327, Percent_Identity=36.3914373088685, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI13128864, Length=299, Percent_Identity=37.4581939799331, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI17158039, Length=351, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI30795204, Length=351, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI30795202, Length=351, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI62750349, Length=328, Percent_Identity=33.5365853658537, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI62750347, Length=328, Percent_Identity=33.5365853658537, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI153085395, Length=330, Percent_Identity=33.030303030303, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI226529806, Length=324, Percent_Identity=33.641975308642, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI169234807, Length=323, Percent_Identity=34.3653250773994, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI148539870, Length=335, Percent_Identity=33.7313432835821, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI193209491, Length=326, Percent_Identity=33.7423312883436, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17540334, Length=307, Percent_Identity=34.5276872964169, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=307, Percent_Identity=34.5276872964169, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17540332, Length=307, Percent_Identity=34.5276872964169, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25154020, Length=303, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25154022, Length=303, Percent_Identity=33.003300330033, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17537347, Length=292, Percent_Identity=32.5342465753425, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534739, Length=314, Percent_Identity=25.1592356687898, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508561, Length=280, Percent_Identity=24.6428571428571, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=35.6466876971609, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325141, Length=286, Percent_Identity=24.1258741258741, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=258, Percent_Identity=26.3565891472868, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=27.8409090909091, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323999, Length=308, Percent_Identity=24.025974025974, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360899, Length=303, Percent_Identity=34.983498349835, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24642146, Length=303, Percent_Identity=35.3135313531353, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24642142, Length=303, Percent_Identity=35.3135313531353, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24642144, Length=303, Percent_Identity=35.3135313531353, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24641720, Length=350, Percent_Identity=33.7142857142857, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281360799, Length=350, Percent_Identity=33.7142857142857, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281360801, Length=350, Percent_Identity=33.7142857142857, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24657891, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33774; Mature: 33643

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGYYTHPSFLMHEMGHFHPECPERLQAIEDHLISHGMDGLLDRREAPAATDAQIERVH
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHC
RPEYVASLVAMSPATGYHPIDPDTLMNPHTLTAARHAAGAAVAATDAVIAGELENAFCCA
CHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEC
RPPGHHAEPDRAMGFCFFDNVAIAARHALTAHGLSRVAIVDFDVHHGNGTEAAFRDDPQV
CCCCCCCCCCHHEEEEEECCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCHH
LMCSFFQHPFYPYSGTEHFAPNMSNIPLPAYSNGLAVREVVETIWLPRLNEFKPEMLFIS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
AGFDAHREDDLGQMGLVEQDYAWITQQLVDVARAHAKGRIVSCLEGGYNLSALARSVFAH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LKVLVET
HHHHHCC
>Mature Secondary Structure 
STGYYTHPSFLMHEMGHFHPECPERLQAIEDHLISHGMDGLLDRREAPAATDAQIERVH
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHC
RPEYVASLVAMSPATGYHPIDPDTLMNPHTLTAARHAAGAAVAATDAVIAGELENAFCCA
CHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEC
RPPGHHAEPDRAMGFCFFDNVAIAARHALTAHGLSRVAIVDFDVHHGNGTEAAFRDDPQV
CCCCCCCCCCHHEEEEEECCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCHH
LMCSFFQHPFYPYSGTEHFAPNMSNIPLPAYSNGLAVREVVETIWLPRLNEFKPEMLFIS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
AGFDAHREDDLGQMGLVEQDYAWITQQLVDVARAHAKGRIVSCLEGGYNLSALARSVFAH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LKVLVET
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]