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The map label for this gene is rutG [H]

Identifier: 94309675

GI number: 94309675

Start: 807191

End: 808639

Strand: Direct

Name: rutG [H]

Synonym: Rmet_0730

Alternate gene names: 94309675

Gene position: 807191-808639 (Clockwise)

Preceding gene: 94309674

Following gene: 94309676

Centisome position: 20.55

GC content: 64.39

Gene sequence:

>1449_bases
ATGCGCAACGCCACTGCCGACAGCGGTCGCCGGGCCGTGCAATCCGACAAAACCATCGAACAAGACCAACCAACTGGCGT
GCCTGGTGTGAACCGGGCCGCCGCTGAAAAGGGAGAGAACAACATGGCGAATGGCCAGGGCAATGCGGGGGGGGAAGGTT
TTTTTCCGAAGTGGCGGCTCAAGACCGAGGGCGTGATCGGCCCCGACGAGCGCCTGCCCGCTGGACAGACGCTGCTGGCG
GGTATCCAGCACGTGGTGGCGATGTTCGGGTCGACCGCAATCGCGCCGATCCTGATGGGTTTCCATCCTAATATCGCCAT
CCTGTTCTCGGGCATCGGCACCCTGCTGTTCTTCCTTTTCGTTCGCGGTCGCGTGCCGAGCTATCTCGGCTCGAGCTTTG
CCTTCATCGCCGTTGTCATCGCGGCCACTGGCTATGCGGGCAGTGGTCCCAATCCCAATATTCCCCTGGCGCTGGGCGGC
ATCATCGCGGCGGGCGCGTTATATACGGTCATCGGCCTCATCGTGCAGGCAGTTGGCTACGGTTGGGTGGAAAAGCTGAT
GCCGCCGGTCGTGACTGGCGCGATCGTCGCGGCAATCGGCCTGAACCTGGCGCCGGTGGCGGTCAAGGCGGTCAGCGCCG
CGCCGCTCGATACCTGGGTGGGTTTGCTGACGGTGCTGGCTGTCGGCCTGATCGCCGTGCGCGCGCCAGGTATGCTTGGC
CGCTTGCCGGTGCTGCTGGGCGGACTGGCCGGCTATCTCGCCTACTACATTGCCACCAACCTGATGGGGCTGGGCAAGGC
CATCGACTTTTCGGGAGTGGCGGCGGCGAACTGGTTCGGCATGCCGGAGTTCACGGCGCCGGTATTCCAGGCCAATGCCA
TGCTGCTGATCGCGCCTGTGGCCATCGTGCTCGTGGCGGAGAATCTCGGGCATATCAAGGCGATCGGCGTTATGACCGGC
CGCAACCTCGATCCGTACATCGGCCGCGCCTTCATCGGTGACGGCGTGGCAACGATGTTGTCGGCGGCGGGTGGTGGCAC
CGGCGTGACCACCTACGCCGAGAATATGGGCGTGATGGCGGTGACCAAGATCTATTCGACGCTGATCTTCGTGGTGGCGG
CCGCCGTGGCTATCCTGCTCGGCTTCTCACCGAAATTCGGTGCACTGATCCTGACGATCCCGGGGCCGGTGATCGGGGGC
CTGACCATCGTCGTGTTCGGCCTGATTTCGGCGACGGCCGGCCGCATCTGGGTGCAGAACCACGTCGATTTCTCCAGCTC
GCGCAATCTGATTACCGTGGGCGCCACTCTGACGGTGGCTGCTGGCGATTTGACCCTGAAGCTGGGCGGCCTGACGCTTG
GCGGCATCGGTACCGCCACGTTTGGCGCCATCCTGCTGTACCACCTGCTCGGCAAGGGCCGGACGCAGGAGCAGGGCCTG
ACGCATTGA

Upstream 100 bases:

>100_bases
TGACGCCAGCGGATCCGCACCCGGGTCAACAATCGCAGGCTGGTATGCGTTGTGCTTGCGGCACGAGGTGCCGTTTGCAC
GGCCCGGGGTGCGGAGTATC

Downstream 100 bases:

>100_bases
TCCACCAAAGGGAATCCCGCCGGCTGGCCGCCTGGAAATGGCCCGGCCGCCGGTGCGGATAAGTTGGGTGCATTACAATG
GCCTGCGAAAAACCGACCGA

Product: pyrimidine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MRNATADSGRRAVQSDKTIEQDQPTGVPGVNRAAAEKGENNMANGQGNAGGEGFFPKWRLKTEGVIGPDERLPAGQTLLA
GIQHVVAMFGSTAIAPILMGFHPNIAILFSGIGTLLFFLFVRGRVPSYLGSSFAFIAVVIAATGYAGSGPNPNIPLALGG
IIAAGALYTVIGLIVQAVGYGWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSAAPLDTWVGLLTVLAVGLIAVRAPGMLG
RLPVLLGGLAGYLAYYIATNLMGLGKAIDFSGVAAANWFGMPEFTAPVFQANAMLLIAPVAIVLVAENLGHIKAIGVMTG
RNLDPYIGRAFIGDGVATMLSAAGGGTGVTTYAENMGVMAVTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGG
LTIVVFGLISATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLTLKLGGLTLGGIGTATFGAILLYHLLGKGRTQEQGL
TH

Sequences:

>Translated_482_residues
MRNATADSGRRAVQSDKTIEQDQPTGVPGVNRAAAEKGENNMANGQGNAGGEGFFPKWRLKTEGVIGPDERLPAGQTLLA
GIQHVVAMFGSTAIAPILMGFHPNIAILFSGIGTLLFFLFVRGRVPSYLGSSFAFIAVVIAATGYAGSGPNPNIPLALGG
IIAAGALYTVIGLIVQAVGYGWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSAAPLDTWVGLLTVLAVGLIAVRAPGMLG
RLPVLLGGLAGYLAYYIATNLMGLGKAIDFSGVAAANWFGMPEFTAPVFQANAMLLIAPVAIVLVAENLGHIKAIGVMTG
RNLDPYIGRAFIGDGVATMLSAAGGGTGVTTYAENMGVMAVTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGG
LTIVVFGLISATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLTLKLGGLTLGGIGTATFGAILLYHLLGKGRTQEQGL
TH
>Mature_482_residues
MRNATADSGRRAVQSDKTIEQDQPTGVPGVNRAAAEKGENNMANGQGNAGGEGFFPKWRLKTEGVIGPDERLPAGQTLLA
GIQHVVAMFGSTAIAPILMGFHPNIAILFSGIGTLLFFLFVRGRVPSYLGSSFAFIAVVIAATGYAGSGPNPNIPLALGG
IIAAGALYTVIGLIVQAVGYGWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSAAPLDTWVGLLTVLAVGLIAVRAPGMLG
RLPVLLGGLAGYLAYYIATNLMGLGKAIDFSGVAAANWFGMPEFTAPVFQANAMLLIAPVAIVLVAENLGHIKAIGVMTG
RNLDPYIGRAFIGDGVATMLSAAGGGTGVTTYAENMGVMAVTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGG
LTIVVFGLISATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLTLKLGGLTLGGIGTATFGAILLYHLLGKGRTQEQGL
TH

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=240, Percent_Identity=26.25, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI44680143, Length=240, Percent_Identity=26.25, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081818, Length=422, Percent_Identity=64.6919431279621, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1788843, Length=431, Percent_Identity=36.4269141531323, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI87082181, Length=437, Percent_Identity=28.3752860411899, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87082178, Length=381, Percent_Identity=25.9842519685039, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558856, Length=421, Percent_Identity=24.7030878859857, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=164, Percent_Identity=35.3658536585366, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541904, Length=253, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=164, Percent_Identity=35.9756097560976, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542262, Length=134, Percent_Identity=35.8208955223881, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356175, Length=171, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49167; Mature: 49167

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNATADSGRRAVQSDKTIEQDQPTGVPGVNRAAAEKGENNMANGQGNAGGEGFFPKWRL
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
KTEGVIGPDERLPAGQTLLAGIQHVVAMFGSTAIAPILMGFHPNIAILFSGIGTLLFFLF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VRGRVPSYLGSSFAFIAVVIAATGYAGSGPNPNIPLALGGIIAAGALYTVIGLIVQAVGY
HHCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSAAPLDTWVGLLTVLAVGLIAVRAPGMLG
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHH
RLPVLLGGLAGYLAYYIATNLMGLGKAIDFSGVAAANWFGMPEFTAPVFQANAMLLIAPV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHCCCHHHHHHH
AIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSAAGGGTGVTTYAENMGVMA
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHCCCHHH
VTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVVFGLISATAGRIWVQN
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEE
HVDFSSSRNLITVGATLTVAAGDLTLKLGGLTLGGIGTATFGAILLYHLLGKGRTQEQGL
CCCCCCCCCEEEECCEEEEEECCEEEEECCEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
TH
CC
>Mature Secondary Structure
MRNATADSGRRAVQSDKTIEQDQPTGVPGVNRAAAEKGENNMANGQGNAGGEGFFPKWRL
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
KTEGVIGPDERLPAGQTLLAGIQHVVAMFGSTAIAPILMGFHPNIAILFSGIGTLLFFLF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VRGRVPSYLGSSFAFIAVVIAATGYAGSGPNPNIPLALGGIIAAGALYTVIGLIVQAVGY
HHCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSAAPLDTWVGLLTVLAVGLIAVRAPGMLG
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHH
RLPVLLGGLAGYLAYYIATNLMGLGKAIDFSGVAAANWFGMPEFTAPVFQANAMLLIAPV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHCCCHHHHHHH
AIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSAAGGGTGVTTYAENMGVMA
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHCCCHHH
VTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVVFGLISATAGRIWVQN
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEE
HVDFSSSRNLITVGATLTVAAGDLTLKLGGLTLGGIGTATFGAILLYHLLGKGRTQEQGL
CCCCCCCCCEEEECCEEEEEECCEEEEECCEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
TH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]