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The map label for this gene is fdsA [H]

Identifier: 94309500

GI number: 94309500

Start: 593044

End: 595917

Strand: Direct

Name: fdsA [H]

Synonym: Rmet_0555

Alternate gene names: 94309500

Gene position: 593044-595917 (Clockwise)

Preceding gene: 94309499

Following gene: 94309501

Centisome position: 15.1

GC content: 64.23

Gene sequence:

>2874_bases
TTGAACGCTCGAGACGATTTCGACTACGGTACCCCGGCCAGCGACGCCGAAACGCAGGTTACGCTGGAAATCGACGGGGT
ATCCGTCACCGTGCCAGCCGGCACCTCCGTGATGCGCGCCGCCGCCGAGGCGGGCGTGGGCGTGCCGAAGCTCTGCGCCA
CCGATTCGCTGAAGGCATTCGGATCGTGCCGCCTGTGCCTGGTGGAGATCGAAGGCCGGCGCGGCTACCCGGCTTCTTGC
ACCACGCCCGTTGAAGCGGGTATGAAGGTGCGCACGCAAAGCGAAAAGCTCGGCGATCTGCGCCGTGGCGTGATGGAGCT
CTATATCTCCGATCACCCGCTCGATTGCCTGACCTGCCCGACCAACGGCAACTGCGAGTTGCAGGACATGGCCGGCGTGG
TGGGCCTGCGCGAAGTGCGATACAACGATGGCGCCGGCACTGCCCCGCCGATCGCCACGCACACGCATCTGGCCAAGGAT
GAATCGAATCCGTACTTCACGTATGACCCATCCAAGTGCATCGTCTGCAATCGCTGCGTGCGTGCCTGCGAGGAGACGCA
AGGCACGTTCGCGCTGACGATCAGCGGCCGGGGCTTTGATTCGCGTGTGGCGGCCGGCACCAGCCAGCCGTTCATGGAAT
CGGACTGCGTGTCGTGTGGCGCCTGCGTCCAGGCGTGTCCCACCGCCACGCTGACGGAAACGTCGGTGATCCAGCTGGGC
CAGGCGTCCCACAGCAAGATCACCACGTGCGCGTACTGCGGCGTGGGATGCTCGTTCAAGGCCGAGATGAAGGGCAACGA
GGTCGTGCGGATGGTGCCGTACAAGGACGGCGCCGCCAACGAGGGTCATGCCTGCGTGAAGGGCCGCTTCGCGTGGGGCT
ATGCCACGCACAAGGACCGCATCCTGAAGCCGATGATTCGCGCCAGGATCACCGACCCGTGGAGGGAAGTGTCGTGGGAG
GAGGCGATCGGATACGCGGCGTCGCAGTTCCGACGCATCCAGGCCGAGCACGGCAAGGATTCGATTGGCGGTATCGTTTC
GTCGCGCTGCACCAACGAGGAAGGCTATCTGGTGCAGAAGCTCGTGCGAGCCGCATTCGGCAACAACAACGTCGACACCT
GCGCGCGTGTCTGCCATTCCCCCACCGGCTACGGCCTGAAGACGACCATCGGTGAATCCGCCGGCACGCAGACGTTCCGC
TCGGTGGCCAAGGCCGACGTGATCATGGTCATCGGCGCCAATCCGACCGACGGGCACCCGGTGTTCGCCTCGCGCATGAA
GCGACGCCTGCGCGCCGGGGCCCGGCTGATCGTGGTCGATCCGCGCCGCATCGATCTGGTGGAATCGCCGCATATCCGCG
CCGACTATCACCTGCAATTGCGTCCGGGCACCAATGTGGCGGTGGTGACGTCGATCGCGCACGTGATCGTCACGGAGGGG
CTGCTGGCCGAGCAATTCATCGCCGAGCGTTGCGAGGACCGCGCGTTCCAGCAATGGCGAGATTTCGTCGCGCTGCCCGA
GAACTCGCCCGAGGCACTCGAAGCGGAGACCGGTGTGCCGGCCGAACAACTGCGTGGCGCAGCCCGCCTCTACGCCACCG
GCGGCAACGCTGCGATCTACTACGGTCTGGGCGTGACCGAACATGCGCAGGGTTCGACCACGGTAATGGCCATCGCCAAT
CTGGCCATGGCCACCGGCAATATCGGTCGCGAAGGCGTGGGCGTCAATCCGCTGCGCGGCCAGAACAACGTGCAGGGGTC
GTGCGATATCGGCTCGTTCCCGCATGAGCTTCCGGGCTACCGTCATGTGTCGGACTCGACGGTGCGTGGCAGCTTCGAGG
CCGCGTGGAATGTCGAGATCAACCCCGAGCCCGGTCTGCGTATTCCGAACATGTTCGAAGCGGCGATTACCGGATCGTTC
CGGGGTCTGTACTGTCAGGGCGAGGACATTGTCCAGTCCGACCCAAATACGCAGCACGTGGCCGAAGCGCTGTCGTCGAT
GGAGTGCATCGTCGTGCAGGATATCTTCCTGAACGAAACCGCCAAGTACGCACACGTGTTCCTGCCGGGTTCGTCGTTCC
TGGAGAAGGACGGCACGTTCACCAACGCGGAGCGCCGGATCTCGCGCGTGCGCAAGGTGATGCCGCCGAAGGCCGGATAC
TCGGACTGGGAGGCAACGATCCTGCTGTCGAACGCGCTCGGTTATCCGATGCACTACAACCATCCGTCCGAGATCATGGA
CGAGATTGCGCGCCTCACACCCACGTTTGCGGGTGTCAGCTACAAGAAGCTTGAGGAACTTGGCAGCATCCAGTGGCCGT
GTAATGCCGAGGCCCCGGAGGGCACGCCGACCATGCACGTGGACACTTTCGTGCGCGGCAAGGGCAAGTTCATCATCACG
AAGTACGTGCCGACCAGCGAAAAGGTCAACCGAAAGTACCCGCTGATCCTGACCACGGGGCGCATCCTGTCCCAATACAA
CGTTGGCGCGCAGACACGGCGCACGCACAACGTGCATTGGCACGATGAGGACCGCCTCGAGATCCATCCGCACGATGCGG
AGGAACGCGGGATCAAGGACGGCGACTGGGTCGGGATTCAGAGCCGTGCCGGTGAAACGGTGCTGCGAGCGATCGTCAGC
GAGCGGATGCAGCCCGGCGTGGTCTATACGACGTTCCACTTCCCCGAGTCCGGCGCCAACGTGATCACGACCGACAACTC
GGACTGGGCCACTAATTGCCCGGAGTACAAGGTGACGGCCGTGCAGGTGATGCCGGTGGCGCAGCCCTCCACGTGGCAGC
GCAACTACCATGCCTTCAACGAGGAACAGCTGGCACATCTGCGCGCGGCCGGCGAACCCACACCGACGCGATGA

Upstream 100 bases:

>100_bases
AAGGCAGCCTGAACGCGGCCTGAGCGCGGCAATCAAAAAAAGCACGACGCGCTCCTCAGGAGCGCGCGACCTCACAGCAG
TGAAAGACGGGAGACATCCC

Downstream 100 bases:

>100_bases
GCCAGGGAGCACGGCGATGAAGCGAGACATGCCTGACGAGAACGGCCTGGGTGAAGCTGGAGTATTGCCAGTGCAGCACA
CGCGTGCGGTCACGCGCTGG

Product: NAD-dependent formate dehydrogenase subunit alpha

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 957; Mature: 957

Protein sequence:

>957_residues
MNARDDFDYGTPASDAETQVTLEIDGVSVTVPAGTSVMRAAAEAGVGVPKLCATDSLKAFGSCRLCLVEIEGRRGYPASC
TTPVEAGMKVRTQSEKLGDLRRGVMELYISDHPLDCLTCPTNGNCELQDMAGVVGLREVRYNDGAGTAPPIATHTHLAKD
ESNPYFTYDPSKCIVCNRCVRACEETQGTFALTISGRGFDSRVAAGTSQPFMESDCVSCGACVQACPTATLTETSVIQLG
QASHSKITTCAYCGVGCSFKAEMKGNEVVRMVPYKDGAANEGHACVKGRFAWGYATHKDRILKPMIRARITDPWREVSWE
EAIGYAASQFRRIQAEHGKDSIGGIVSSRCTNEEGYLVQKLVRAAFGNNNVDTCARVCHSPTGYGLKTTIGESAGTQTFR
SVAKADVIMVIGANPTDGHPVFASRMKRRLRAGARLIVVDPRRIDLVESPHIRADYHLQLRPGTNVAVVTSIAHVIVTEG
LLAEQFIAERCEDRAFQQWRDFVALPENSPEALEAETGVPAEQLRGAARLYATGGNAAIYYGLGVTEHAQGSTTVMAIAN
LAMATGNIGREGVGVNPLRGQNNVQGSCDIGSFPHELPGYRHVSDSTVRGSFEAAWNVEINPEPGLRIPNMFEAAITGSF
RGLYCQGEDIVQSDPNTQHVAEALSSMECIVVQDIFLNETAKYAHVFLPGSSFLEKDGTFTNAERRISRVRKVMPPKAGY
SDWEATILLSNALGYPMHYNHPSEIMDEIARLTPTFAGVSYKKLEELGSIQWPCNAEAPEGTPTMHVDTFVRGKGKFIIT
KYVPTSEKVNRKYPLILTTGRILSQYNVGAQTRRTHNVHWHDEDRLEIHPHDAEERGIKDGDWVGIQSRAGETVLRAIVS
ERMQPGVVYTTFHFPESGANVITTDNSDWATNCPEYKVTAVQVMPVAQPSTWQRNYHAFNEEQLAHLRAAGEPTPTR

Sequences:

>Translated_957_residues
MNARDDFDYGTPASDAETQVTLEIDGVSVTVPAGTSVMRAAAEAGVGVPKLCATDSLKAFGSCRLCLVEIEGRRGYPASC
TTPVEAGMKVRTQSEKLGDLRRGVMELYISDHPLDCLTCPTNGNCELQDMAGVVGLREVRYNDGAGTAPPIATHTHLAKD
ESNPYFTYDPSKCIVCNRCVRACEETQGTFALTISGRGFDSRVAAGTSQPFMESDCVSCGACVQACPTATLTETSVIQLG
QASHSKITTCAYCGVGCSFKAEMKGNEVVRMVPYKDGAANEGHACVKGRFAWGYATHKDRILKPMIRARITDPWREVSWE
EAIGYAASQFRRIQAEHGKDSIGGIVSSRCTNEEGYLVQKLVRAAFGNNNVDTCARVCHSPTGYGLKTTIGESAGTQTFR
SVAKADVIMVIGANPTDGHPVFASRMKRRLRAGARLIVVDPRRIDLVESPHIRADYHLQLRPGTNVAVVTSIAHVIVTEG
LLAEQFIAERCEDRAFQQWRDFVALPENSPEALEAETGVPAEQLRGAARLYATGGNAAIYYGLGVTEHAQGSTTVMAIAN
LAMATGNIGREGVGVNPLRGQNNVQGSCDIGSFPHELPGYRHVSDSTVRGSFEAAWNVEINPEPGLRIPNMFEAAITGSF
RGLYCQGEDIVQSDPNTQHVAEALSSMECIVVQDIFLNETAKYAHVFLPGSSFLEKDGTFTNAERRISRVRKVMPPKAGY
SDWEATILLSNALGYPMHYNHPSEIMDEIARLTPTFAGVSYKKLEELGSIQWPCNAEAPEGTPTMHVDTFVRGKGKFIIT
KYVPTSEKVNRKYPLILTTGRILSQYNVGAQTRRTHNVHWHDEDRLEIHPHDAEERGIKDGDWVGIQSRAGETVLRAIVS
ERMQPGVVYTTFHFPESGANVITTDNSDWATNCPEYKVTAVQVMPVAQPSTWQRNYHAFNEEQLAHLRAAGEPTPTR
>Mature_957_residues
MNARDDFDYGTPASDAETQVTLEIDGVSVTVPAGTSVMRAAAEAGVGVPKLCATDSLKAFGSCRLCLVEIEGRRGYPASC
TTPVEAGMKVRTQSEKLGDLRRGVMELYISDHPLDCLTCPTNGNCELQDMAGVVGLREVRYNDGAGTAPPIATHTHLAKD
ESNPYFTYDPSKCIVCNRCVRACEETQGTFALTISGRGFDSRVAAGTSQPFMESDCVSCGACVQACPTATLTETSVIQLG
QASHSKITTCAYCGVGCSFKAEMKGNEVVRMVPYKDGAANEGHACVKGRFAWGYATHKDRILKPMIRARITDPWREVSWE
EAIGYAASQFRRIQAEHGKDSIGGIVSSRCTNEEGYLVQKLVRAAFGNNNVDTCARVCHSPTGYGLKTTIGESAGTQTFR
SVAKADVIMVIGANPTDGHPVFASRMKRRLRAGARLIVVDPRRIDLVESPHIRADYHLQLRPGTNVAVVTSIAHVIVTEG
LLAEQFIAERCEDRAFQQWRDFVALPENSPEALEAETGVPAEQLRGAARLYATGGNAAIYYGLGVTEHAQGSTTVMAIAN
LAMATGNIGREGVGVNPLRGQNNVQGSCDIGSFPHELPGYRHVSDSTVRGSFEAAWNVEINPEPGLRIPNMFEAAITGSF
RGLYCQGEDIVQSDPNTQHVAEALSSMECIVVQDIFLNETAKYAHVFLPGSSFLEKDGTFTNAERRISRVRKVMPPKAGY
SDWEATILLSNALGYPMHYNHPSEIMDEIARLTPTFAGVSYKKLEELGSIQWPCNAEAPEGTPTMHVDTFVRGKGKFIIT
KYVPTSEKVNRKYPLILTTGRILSQYNVGAQTRRTHNVHWHDEDRLEIHPHDAEERGIKDGDWVGIQSRAGETVLRAIVS
ERMQPGVVYTTFHFPESGANVITTDNSDWATNCPEYKVTAVQVMPVAQPSTWQRNYHAFNEEQLAHLRAAGEPTPTR

Specific function: Decomposes Formic Acid To Hydrogen And Carbon Dioxide Under Anaerobic Conditions In The Absence Of Exogenous Electron Acceptors. [C]

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=423, Percent_Identity=28.6052009456265, Blast_Score=169, Evalue=8e-42,
Organism=Escherichia coli, GI3868721, Length=694, Percent_Identity=38.1844380403458, Blast_Score=480, Evalue=1e-136,
Organism=Escherichia coli, GI1788534, Length=822, Percent_Identity=24.9391727493917, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI3868720, Length=621, Percent_Identity=25.7648953301127, Blast_Score=174, Evalue=3e-44,
Organism=Escherichia coli, GI3868719, Length=620, Percent_Identity=25, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787778, Length=684, Percent_Identity=23.6842105263158, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI87081797, Length=730, Percent_Identity=24.2465753424658, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI145693161, Length=424, Percent_Identity=26.1792452830189, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI171474008, Length=778, Percent_Identity=24.0359897172237, Blast_Score=120, Evalue=6e-28,
Organism=Escherichia coli, GI1787870, Length=498, Percent_Identity=25.9036144578313, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI87081994, Length=770, Percent_Identity=21.9480519480519, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI145693196, Length=463, Percent_Identity=22.8941684665227, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565758, Length=412, Percent_Identity=28.3980582524272, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32566231, Length=412, Percent_Identity=28.3980582524272, Blast_Score=153, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193209088, Length=214, Percent_Identity=33.6448598130841, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24640559, Length=542, Percent_Identity=25.830258302583, Blast_Score=156, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24640557, Length=542, Percent_Identity=25.830258302583, Blast_Score=156, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: 1.2.1.2

Molecular weight: Translated: 104399; Mature: 104399

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00932 MOLYBDOPTERIN_PROK_3 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARDDFDYGTPASDAETQVTLEIDGVSVTVPAGTSVMRAAAEAGVGVPKLCATDSLKAF
CCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHCCCCCCCHHCCCCHHHC
GSCRLCLVEIEGRRGYPASCTTPVEAGMKVRTQSEKLGDLRRGVMELYISDHPLDCLTCP
CCCEEEEEEEECCCCCCCCCCCHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEECC
TNGNCELQDMAGVVGLREVRYNDGAGTAPPIATHTHLAKDESNPYFTYDPSKCIVCNRCV
CCCCEEHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
RACEETQGTFALTISGRGFDSRVAAGTSQPFMESDCVSCGACVQACPTATLTETSVIQLG
HHHHHCCCEEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHEEC
QASHSKITTCAYCGVGCSFKAEMKGNEVVRMVPYKDGAANEGHACVKGRFAWGYATHKDR
CCCCCCEEEEEEECCCCCEEECCCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCHHH
ILKPMIRARITDPWREVSWEEAIGYAASQFRRIQAEHGKDSIGGIVSSRCTNEEGYLVQK
HHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHH
LVRAAFGNNNVDTCARVCHSPTGYGLKTTIGESAGTQTFRSVAKADVIMVIGANPTDGHP
HHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCCC
VFASRMKRRLRAGARLIVVDPRRIDLVESPHIRADYHLQLRPGTNVAVVTSIAHVIVTEG
HHHHHHHHHHHHCCEEEEECCCEEEEECCCCCCEEEEEEECCCCCEEHHHHHHHHHHHCC
LLAEQFIAERCEDRAFQQWRDFVALPENSPEALEAETGVPAEQLRGAARLYATGGNAAIY
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCEEEE
YGLGVTEHAQGSTTVMAIANLAMATGNIGREGVGVNPLRGQNNVQGSCDIGSFPHELPGY
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RHVSDSTVRGSFEAAWNVEINPEPGLRIPNMFEAAITGSFRGLYCQGEDIVQSDPNTQHV
CCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEECCCHHHCCCCCHHHH
AEALSSMECIVVQDIFLNETAKYAHVFLPGSSFLEKDGTFTNAERRISRVRKVMPPKAGY
HHHHHCCCEEEEEHHHHCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
SDWEATILLSNALGYPMHYNHPSEIMDEIARLTPTFAGVSYKKLEELGSIQWPCNAEAPE
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHCCCCHHHHHHHCCCCCCCCCCCCC
GTPTMHVDTFVRGKGKFIITKYVPTSEKVNRKYPLILTTGRILSQYNVGAQTRRTHNVHW
CCCEEEEEEEEECCCCEEEEEECCCCHHCCCCCCEEEECCHHHHHCCCCCCCCCCCCCCC
HDEDRLEIHPHDAEERGIKDGDWVGIQSRAGETVLRAIVSERMQPGVVYTTFHFPESGAN
CCCCCEEECCCCHHHCCCCCCCEEEEHHHCHHHHHHHHHHHHCCCCEEEEEEECCCCCCE
VITTDNSDWATNCPEYKVTAVQVMPVAQPSTWQRNYHAFNEEQLAHLRAAGEPTPTR
EEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNARDDFDYGTPASDAETQVTLEIDGVSVTVPAGTSVMRAAAEAGVGVPKLCATDSLKAF
CCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHCCCCCCCHHCCCCHHHC
GSCRLCLVEIEGRRGYPASCTTPVEAGMKVRTQSEKLGDLRRGVMELYISDHPLDCLTCP
CCCEEEEEEEECCCCCCCCCCCHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEECC
TNGNCELQDMAGVVGLREVRYNDGAGTAPPIATHTHLAKDESNPYFTYDPSKCIVCNRCV
CCCCEEHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
RACEETQGTFALTISGRGFDSRVAAGTSQPFMESDCVSCGACVQACPTATLTETSVIQLG
HHHHHCCCEEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHEEC
QASHSKITTCAYCGVGCSFKAEMKGNEVVRMVPYKDGAANEGHACVKGRFAWGYATHKDR
CCCCCCEEEEEEECCCCCEEECCCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCHHH
ILKPMIRARITDPWREVSWEEAIGYAASQFRRIQAEHGKDSIGGIVSSRCTNEEGYLVQK
HHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHH
LVRAAFGNNNVDTCARVCHSPTGYGLKTTIGESAGTQTFRSVAKADVIMVIGANPTDGHP
HHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCCC
VFASRMKRRLRAGARLIVVDPRRIDLVESPHIRADYHLQLRPGTNVAVVTSIAHVIVTEG
HHHHHHHHHHHHCCEEEEECCCEEEEECCCCCCEEEEEEECCCCCEEHHHHHHHHHHHCC
LLAEQFIAERCEDRAFQQWRDFVALPENSPEALEAETGVPAEQLRGAARLYATGGNAAIY
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCEEEE
YGLGVTEHAQGSTTVMAIANLAMATGNIGREGVGVNPLRGQNNVQGSCDIGSFPHELPGY
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RHVSDSTVRGSFEAAWNVEINPEPGLRIPNMFEAAITGSFRGLYCQGEDIVQSDPNTQHV
CCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEECCCHHHCCCCCHHHH
AEALSSMECIVVQDIFLNETAKYAHVFLPGSSFLEKDGTFTNAERRISRVRKVMPPKAGY
HHHHHCCCEEEEEHHHHCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
SDWEATILLSNALGYPMHYNHPSEIMDEIARLTPTFAGVSYKKLEELGSIQWPCNAEAPE
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHCCCCHHHHHHHCCCCCCCCCCCCC
GTPTMHVDTFVRGKGKFIITKYVPTSEKVNRKYPLILTTGRILSQYNVGAQTRRTHNVHW
CCCEEEEEEEEECCCCEEEEEECCCCHHCCCCCCEEEECCHHHHHCCCCCCCCCCCCCCC
HDEDRLEIHPHDAEERGIKDGDWVGIQSRAGETVLRAIVSERMQPGVVYTTFHFPESGAN
CCCCCEEECCCCHHHCCCCCCCEEEEHHHCHHHHHHHHHHHHCCCCEEEEEEECCCCCCE
VITTDNSDWATNCPEYKVTAVQVMPVAQPSTWQRNYHAFNEEQLAHLRAAGEPTPTR
EEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: Fe; Mo; Se [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.19 {3-pyridinecarboxaldehyde-NAD+}} 0.032 {NAD+}} 1.16 {3-acetylpyridine-NAD+}} 0.54 {deamino-NAD+}} 0.17 {thio-NAD+}} [C]

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: Redox reaction [C]

Inhibitor: Azide; Br-; Cl-; CN-; F-; HCO3-; HCOS-; NO2-; NO3-; OCN-; SCN- [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]