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The map label for this gene is yfeR [H]

Identifier: 94309473

GI number: 94309473

Start: 563893

End: 564798

Strand: Direct

Name: yfeR [H]

Synonym: Rmet_0528

Alternate gene names: 94309473

Gene position: 563893-564798 (Clockwise)

Preceding gene: 94309471

Following gene: 94309475

Centisome position: 14.36

GC content: 67.11

Gene sequence:

>906_bases
ATGAATTACACACTGCGGCAGTTGCGGGTCTTTCTGGCGGTGGCGGGGCATGGCAGTTTCAGCCGGGCAGCGGATGCCGT
CGGGCTGACGCAGCCGGCGGTCAGTCGGGGTGTTGCCGAGCTTGAAGAGGCACTTGGCGTACGTCTGCTGGATCGTACGA
CTCGGGAAGTCGTGCTGACGGAGGCTGGAACGGCACTGGTACCAGCGCTGGAGCGGCTGCTGGGCCAGCTTGACGACACC
CTGGAAGAGACACGGCAGTCCGGCGAACGCTATCGCGGCCGGGTTGTGATAGCCAGTGCGCCGACGATCTCGGCGCGACT
AATGCCGATGTATGTGGCGGCCTGCGCGAGCCAGTATCCCGATATCCGGTTGTTCGTGCGCGACAACGTCCAGGCCGACG
GCCTCGAGCAGATCCGCGCCGGCGCGGTCGATTTCGGGGTGTTGATCGATCCGATGGCGCGCGAGGGGCTGACTATCGCG
CCGCTCGCCACCGATCCGTTCTGTTTCGTATGTCGGCGCGACCATCCACTGGCCGAGGCGGATTCGGTGCCCTGGACCGC
GTTGCACGGCGAGCGCCTGGTGCTGCTCGATTTTGCCTCCGGCAGCCGGCCGTTGATCGACCGGATCTTCGCTCGTCATG
GCGCGGTGCCGCAGGTGGTGCAGGAACTCGGGCACTCCGCCAGCGTATTCGGCATGGTGGAGGCGGGGATCGGCGCGTCG
GTCCTGCCGTCCTTCTCGTTGCCGTTGCCCGAGGCGTCCCCGCTGGTCTCGAAGCCGCTGACGCCGCGCGAGGAACGCAG
CATCGTCATGGTCCGTCGCGAGGACCGGTCGCTGTCACCGGCGGCGGCTGCGGTCTGGAACATGGTCCAGACCATGCCGA
TCCCGGCCGAAACCGCGACCGGCTGA

Upstream 100 bases:

>100_bases
CATTGATAGGGATAGTGCGTAAGGGTTTCCGCTTGGTATTGGACCCTCGTCCTGTCTAGAATGCAAATTCATTTATTTCA
TTCATTCATTTCAACGTTGC

Downstream 100 bases:

>100_bases
CTGCGACGGGCGAGGGGAGGGCTGAGGGGAGGGCTGTTACGCGCGGGGAGAGGCGGCCAACATTGCCGCTTCCAGCGCAA
AGCTGCCGTCGGGCTGCACG

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNYTLRQLRVFLAVAGHGSFSRAADAVGLTQPAVSRGVAELEEALGVRLLDRTTREVVLTEAGTALVPALERLLGQLDDT
LEETRQSGERYRGRVVIASAPTISARLMPMYVAACASQYPDIRLFVRDNVQADGLEQIRAGAVDFGVLIDPMAREGLTIA
PLATDPFCFVCRRDHPLAEADSVPWTALHGERLVLLDFASGSRPLIDRIFARHGAVPQVVQELGHSASVFGMVEAGIGAS
VLPSFSLPLPEASPLVSKPLTPREERSIVMVRREDRSLSPAAAAVWNMVQTMPIPAETATG

Sequences:

>Translated_301_residues
MNYTLRQLRVFLAVAGHGSFSRAADAVGLTQPAVSRGVAELEEALGVRLLDRTTREVVLTEAGTALVPALERLLGQLDDT
LEETRQSGERYRGRVVIASAPTISARLMPMYVAACASQYPDIRLFVRDNVQADGLEQIRAGAVDFGVLIDPMAREGLTIA
PLATDPFCFVCRRDHPLAEADSVPWTALHGERLVLLDFASGSRPLIDRIFARHGAVPQVVQELGHSASVFGMVEAGIGAS
VLPSFSLPLPEASPLVSKPLTPREERSIVMVRREDRSLSPAAAAVWNMVQTMPIPAETATG
>Mature_301_residues
MNYTLRQLRVFLAVAGHGSFSRAADAVGLTQPAVSRGVAELEEALGVRLLDRTTREVVLTEAGTALVPALERLLGQLDDT
LEETRQSGERYRGRVVIASAPTISARLMPMYVAACASQYPDIRLFVRDNVQADGLEQIRAGAVDFGVLIDPMAREGLTIA
PLATDPFCFVCRRDHPLAEADSVPWTALHGERLVLLDFASGSRPLIDRIFARHGAVPQVVQELGHSASVFGMVEAGIGAS
VLPSFSLPLPEASPLVSKPLTPREERSIVMVRREDRSLSPAAAAVWNMVQTMPIPAETATG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=52.7586206896552, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=33.5689045936396, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI157672245, Length=283, Percent_Identity=31.8021201413428, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=33.2, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=29.6703296703297, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.5720164609054, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367136, Length=249, Percent_Identity=30.5220883534137, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787601, Length=191, Percent_Identity=28.7958115183246, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=28.9256198347107, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788481, Length=249, Percent_Identity=28.1124497991968, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=27.8688524590164, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=24.1106719367589, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786401, Length=156, Percent_Identity=33.974358974359, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081904, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790783, Length=261, Percent_Identity=27.2030651340996, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786713, Length=266, Percent_Identity=27.4436090225564, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789173, Length=170, Percent_Identity=31.7647058823529, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790262, Length=241, Percent_Identity=24.4813278008299, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787128, Length=148, Percent_Identity=32.4324324324324, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790011, Length=100, Percent_Identity=36, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789639, Length=145, Percent_Identity=29.6551724137931, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788626, Length=248, Percent_Identity=29.4354838709677, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32429; Mature: 32429

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYTLRQLRVFLAVAGHGSFSRAADAVGLTQPAVSRGVAELEEALGVRLLDRTTREVVLT
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHCCCHHEEEE
EAGTALVPALERLLGQLDDTLEETRQSGERYRGRVVIASAPTISARLMPMYVAACASQYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCC
DIRLFVRDNVQADGLEQIRAGAVDFGVLIDPMAREGLTIAPLATDPFCFVCRRDHPLAEA
CEEEEEECCCCCCCHHHHHHCCCHHHHEECCHHHCCCEEEECCCCCEEEEEECCCCCCCC
DSVPWTALHGERLVLLDFASGSRPLIDRIFARHGAVPQVVQELGHSASVFGMVEAGIGAS
CCCCEEEECCCEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCEEEHHHHCCCCCH
VLPSFSLPLPEASPLVSKPLTPREERSIVMVRREDRSLSPAAAAVWNMVQTMPIPAETAT
HCCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
G
C
>Mature Secondary Structure
MNYTLRQLRVFLAVAGHGSFSRAADAVGLTQPAVSRGVAELEEALGVRLLDRTTREVVLT
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHCCCHHEEEE
EAGTALVPALERLLGQLDDTLEETRQSGERYRGRVVIASAPTISARLMPMYVAACASQYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCC
DIRLFVRDNVQADGLEQIRAGAVDFGVLIDPMAREGLTIAPLATDPFCFVCRRDHPLAEA
CEEEEEECCCCCCCHHHHHHCCCHHHHEECCHHHCCCEEEECCCCCEEEEEECCCCCCCC
DSVPWTALHGERLVLLDFASGSRPLIDRIFARHGAVPQVVQELGHSASVFGMVEAGIGAS
CCCCEEEECCCEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCEEEHHHHCCCCCH
VLPSFSLPLPEASPLVSKPLTPREERSIVMVRREDRSLSPAAAAVWNMVQTMPIPAETAT
HCCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]