Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 94309460

GI number: 94309460

Start: 551784

End: 552518

Strand: Direct

Name: ompR [H]

Synonym: Rmet_0515

Alternate gene names: 94309460

Gene position: 551784-552518 (Clockwise)

Preceding gene: 94309455

Following gene: 94309461

Centisome position: 14.05

GC content: 66.26

Gene sequence:

>735_bases
ATGCGTACAAACCAGCCCACCCAGATTCTCGTCGTCGATGACGATCCCGAACTGCGCGACCTGCTGCGCGAGTACCTGAC
ATCCCAGGGATTCGCGGTTTCCGTGCTCCATGATGGCGACGGCCTGCAGGCGCGACTCGAGCGCGAGCGCCCGGCGCTGA
TCGTGCTCGACCTGATGATGCCAAAGGTCGACGGCCTGACCGCCCTGCGCAATCTGCGCGCCAAGAACGACGATATCCCC
GTGATCCTGCTGACCGCGCGCAGCGACGAGATCGACCGCATCGTCGGGCTGGAGATCGGCGCGGACGACTACCTCGGCAA
GCCGTTCTCGCCACGCGAGTTGCTGGCGCGGATCAATGCCGTGCTGCGCCGCAAGCTGGCCCGCCCGGCTGCCGCACCCG
AGGATCGGGAATCCGTGGTGTTCGGCCCGTTCCGGGTGAACTTCCGCCAGCGCTCGCTCGAACGCAGCGGCCAGTCCGTT
TCCATCAGCGACACCGAATTCGCGCTGCTCAAGCTGCTGCTGTCGCATCCGCTTGAAGTGCTCTCCCGCGAGCGCATCGT
CGAACTGATGTACGGCACCGCCAACGGCATCAGCGACCGGGGCATCGACGTGCAGATCTGGCGCCTGCGCCGCCTGCTCG
ACGAGGACGCCCAGCGCCCGCGCTATATCCAGACCGTACGTGGCCGCGGCTACACCTTTGTGCCGGACGAGGCCGAGGAC
AGCATTCCGCAATGA

Upstream 100 bases:

>100_bases
TTATTACAGCGGATTACCAACGACGTGGGTGTAACCTCCGGAAACAAAACGGTCCGGGACATTTGCAAAGCCGCATGTCC
GGCCTGACTATCATGTGCCT

Downstream 100 bases:

>100_bases
AGCTTCGCATCGATACCCTGTTTGGCCGCATCGCGCTGCTGATCGCGGCCGTGTTGGTGATCAGCCACTTTTCGTGGCTG
GCCATCCTACGCATGGACCG

Product: DNA-binding response regulator in two-component regulatory system with EnvZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRTNQPTQILVVDDDPELRDLLREYLTSQGFAVSVLHDGDGLQARLERERPALIVLDLMMPKVDGLTALRNLRAKNDDIP
VILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINAVLRRKLARPAAAPEDRESVVFGPFRVNFRQRSLERSGQSV
SISDTEFALLKLLLSHPLEVLSRERIVELMYGTANGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAED
SIPQ

Sequences:

>Translated_244_residues
MRTNQPTQILVVDDDPELRDLLREYLTSQGFAVSVLHDGDGLQARLERERPALIVLDLMMPKVDGLTALRNLRAKNDDIP
VILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINAVLRRKLARPAAAPEDRESVVFGPFRVNFRQRSLERSGQSV
SISDTEFALLKLLLSHPLEVLSRERIVELMYGTANGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAED
SIPQ
>Mature_244_residues
MRTNQPTQILVVDDDPELRDLLREYLTSQGFAVSVLHDGDGLQARLERERPALIVLDLMMPKVDGLTALRNLRAKNDDIP
VILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINAVLRRKLARPAAAPEDRESVVFGPFRVNFRQRSLERSGQSV
SISDTEFALLKLLLSHPLEVLSRERIVELMYGTANGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAED
SIPQ

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=51.7391304347826, Blast_Score=227, Evalue=5e-61,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=38.655462184874, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.5172413793103, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=41.5254237288136, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=36.5957446808511, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=37.6623376623377, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=35.3711790393013, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=32.3404255319149, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=33.8912133891213, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=35.4978354978355, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=36.2445414847162, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.3478260869565, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.5132743362832, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.5309734513274, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788550, Length=131, Percent_Identity=31.2977099236641, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=32.7272727272727, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788905, Length=139, Percent_Identity=33.0935251798561, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=142, Percent_Identity=28.8732394366197, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=33.9805825242718, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27694; Mature: 27694

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNQPTQILVVDDDPELRDLLREYLTSQGFAVSVLHDGDGLQARLERERPALIVLDLMM
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCEEEEEEHHH
PKVDGLTALRNLRAKNDDIPVILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINA
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEECCHHHCCCCCCHHHHHHHHHH
VLRRKLARPAAAPEDRESVVFGPFRVNFRQRSLERSGQSVSISDTEFALLKLLLSHPLEV
HHHHHHHCCCCCCCCCCCEEECCEEECHHHHHHHHCCCEEEECHHHHHHHHHHHHCHHHH
LSRERIVELMYGTANGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAED
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCCCC
SIPQ
CCCC
>Mature Secondary Structure
MRTNQPTQILVVDDDPELRDLLREYLTSQGFAVSVLHDGDGLQARLERERPALIVLDLMM
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCEEEEEEHHH
PKVDGLTALRNLRAKNDDIPVILLTARSDEIDRIVGLEIGADDYLGKPFSPRELLARINA
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEECCHHHCCCCCCHHHHHHHHHH
VLRRKLARPAAAPEDRESVVFGPFRVNFRQRSLERSGQSVSISDTEFALLKLLLSHPLEV
HHHHHHHCCCCCCCCCCCEEECCEEECHHHHHHHHCCCEEEECHHHHHHHHHHHHCHHHH
LSRERIVELMYGTANGISDRGIDVQIWRLRRLLDEDAQRPRYIQTVRGRGYTFVPDEAED
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCCCCC
SIPQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]