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The map label for this gene is gmhB [H]

Identifier: 94309390

GI number: 94309390

Start: 471099

End: 471680

Strand: Reverse

Name: gmhB [H]

Synonym: Rmet_0445

Alternate gene names: 94309390

Gene position: 471680-471099 (Counterclockwise)

Preceding gene: 94309391

Following gene: 94309389

Centisome position: 12.01

GC content: 63.23

Gene sequence:

>582_bases
ATGCCACAGTCCCAGTTGAAGTTCGTCATCCTGGATCGCGACGGAGTCATCAACCGCGACAGCGACCAGTTCATCAAGAC
ACCCGACGAATGGATACCCATCGAGGGTAGCCTTGAAGCCATCGCCATGCTGAACCAGGCCGGCTACCGCGTAGTGGTGG
CCAGCAACCAGTCGGGCATCGGCCGCGGCCTGTTCGAGATGAGCGCGCTCAACGCGATGCACGAGAAGATGTACAAGGCG
CTGGCCAACCTCGGTGGCCGCGTCGAAGCCATCTTCTTCTGCCCGCACACGGCAGCCGACAACTGCGACTGCCGCAAACC
CAAATCCGGCCTGTACGAGCAGATTGGCGAGCGGTTCGGCATCGAATTGCGCACCGTGCCCACGGTGGGAGATTCGCTGC
GCGACCTTCAGGCGGGCGTGGCGGTTGGCTGCATCCCGCATCTGGTTCGTACTGGCAAGGGCATGAAAACGCTGGAAAAA
GGCGGCCTGCCCGATGGCACGCGCGTGCATGACGACCTGGCAGCGTTTGCGCGCTGGCTGATCGACGATGCGGCGCCCAA
GCCGCAACCAACCGCGCCCTGA

Upstream 100 bases:

>100_bases
CGCTGTTGGCCACGCTGCACGGCCTGGCGAATCGCGTCGCGGACATTTCGAAGCTGGCGGCCTAAGCTGTCTCATACGCT
GCATCACCGGAACGCGCGCC

Downstream 100 bases:

>100_bases
TATCCGTCCCCGATTACCGCCCCCGATCGATGACTTTCCTCCGTTCCCTGCTGTTCTCGCTGTACCTCCTGGCACTCACG
CCCCCCTATGCGTGCCTTTG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MPQSQLKFVILDRDGVINRDSDQFIKTPDEWIPIEGSLEAIAMLNQAGYRVVVASNQSGIGRGLFEMSALNAMHEKMYKA
LANLGGRVEAIFFCPHTAADNCDCRKPKSGLYEQIGERFGIELRTVPTVGDSLRDLQAGVAVGCIPHLVRTGKGMKTLEK
GGLPDGTRVHDDLAAFARWLIDDAAPKPQPTAP

Sequences:

>Translated_193_residues
MPQSQLKFVILDRDGVINRDSDQFIKTPDEWIPIEGSLEAIAMLNQAGYRVVVASNQSGIGRGLFEMSALNAMHEKMYKA
LANLGGRVEAIFFCPHTAADNCDCRKPKSGLYEQIGERFGIELRTVPTVGDSLRDLQAGVAVGCIPHLVRTGKGMKTLEK
GGLPDGTRVHDDLAAFARWLIDDAAPKPQPTAP
>Mature_192_residues
PQSQLKFVILDRDGVINRDSDQFIKTPDEWIPIEGSLEAIAMLNQAGYRVVVASNQSGIGRGLFEMSALNAMHEKMYKAL
ANLGGRVEAIFFCPHTAADNCDCRKPKSGLYEQIGERFGIELRTVPTVGDSLRDLQAGVAVGCIPHLVRTGKGMKTLEKG
GLPDGTRVHDDLAAFARWLIDDAAPKPQPTAP

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=35.9477124183007, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=29.4964028776978, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 21003; Mature: 20872

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSQLKFVILDRDGVINRDSDQFIKTPDEWIPIEGSLEAIAMLNQAGYRVVVASNQSGI
CCCCCEEEEEECCCCCCCCCCCHHHCCCCCEECCCCCHHHHHHHHCCCCEEEEECCCCCC
GRGLFEMSALNAMHEKMYKALANLGGRVEAIFFCPHTAADNCDCRKPKSGLYEQIGERFG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHC
IELRTVPTVGDSLRDLQAGVAVGCIPHLVRTGKGMKTLEKGGLPDGTRVHDDLAAFARWL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
IDDAAPKPQPTAP
HHCCCCCCCCCCC
>Mature Secondary Structure 
PQSQLKFVILDRDGVINRDSDQFIKTPDEWIPIEGSLEAIAMLNQAGYRVVVASNQSGI
CCCCEEEEEECCCCCCCCCCCHHHCCCCCEECCCCCHHHHHHHHCCCCEEEEECCCCCC
GRGLFEMSALNAMHEKMYKALANLGGRVEAIFFCPHTAADNCDCRKPKSGLYEQIGERFG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHC
IELRTVPTVGDSLRDLQAGVAVGCIPHLVRTGKGMKTLEKGGLPDGTRVHDDLAAFARWL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
IDDAAPKPQPTAP
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]