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The map label for this gene is fadN [H]

Identifier: 94309331

GI number: 94309331

Start: 412352

End: 414778

Strand: Direct

Name: fadN [H]

Synonym: Rmet_0386

Alternate gene names: 94309331

Gene position: 412352-414778 (Clockwise)

Preceding gene: 94309330

Following gene: 94309332

Centisome position: 10.5

GC content: 64.28

Gene sequence:

>2427_bases
ATGTCCAATTTCATCGTCAAGAAGGTCGCTGTGCTCGGTGCCGGCGTCATGGGGGCGCAGATTGCCGCCCATCTGATCAA
CGCCCGCGTTCCCGTGATCCTGTTCGACCTGCCGGCCAAGGAAGGCCCGAAGAACGGTATCGCCGATCGCGCGATCGAGA
ACCTGAAGAAGCTCTCGCCCGCGCCGCTCGGCATCAAGGAAGAGGCCGGCCTGATTCGCGCCGCCAACTACGAGGACGAC
ATCGCCCTGCTCAAGGAGTGCGACGTGGTGATCGAGGCGATCGCCGAGCGCATGGACTGGAAGCATGACCTCTACAAGAA
GGTGTCGCCGCATCTCGCGCCGAACGCAATCTTCGCCACGAACACGTCTGGCCTGTCGATCACGGCGCTGTCCGATGGCT
TCGATGCCGACCTGAAGTCGCGCTTCTGCGGTGTGCACTTCTTCAATCCGCCGCGCTACATGCACCTGGTGGAGCTGATC
CCGACCGCGACGACCAAGCCGGAGATTCTCGACCGTCTGGAATCGTTCCTGACCACGTCGCTGGGCAAGGGTGTCGTGCG
CGCCAAGGACACGTCGAACTTCATCGCCAACCGTGTCGGCATCTTCTCGATCCTGGCCGTGTTCGCCGAAGCCGAGAAGT
TCGGCATTCCGTTCGATATCGTCGACGACCTGACCGGTACCAAGCTGGGCCGCGCCAAGTCGGCCACGTTCCGCACCGCC
GACGTGGTAGGCCTGGACACGATGGCGCACGTCATCAAGACGATGCAGGACAACCTGACCGATGACCCGTTCGCGCCGGT
GTACAAGACGCCGGCCGTGCTGAAGGGGCTGGTGGATGCCGGCGCGCTGGGCCAGAAGACCGGCGCCGGTTTCTACAAGA
AGGAAGGCAAGGCGATCAAGGTGCTGGACGCCAAGTCTGGCCAGTACGTCGAGTCCGGCAAGAAGGCCGACGAGATCGTC
GTGCGCATCCTGAAGAAGGAACCGGCCGAACGTATCAAGCTGCTGCGTGAATCGACCAATCCGCAGGCCCAGTTCCTGTG
GGGCGTGTTCCGTGACGTGTTCCACTACATCGCCGTCTATCTGGAACAGATCGCTGGCTCGGCGGCCGATATCGACCTGG
CCATTCGCTGGGGCTTCGGCTGGAACTCGGGTCCGTTCGAAGATTGGCAGGCCGCTGGCTGGAAGCAGGTGGCCGAGTGG
GTCAAGGAAGATGTCGAGGCAGGCAAGGCGCTCTCGAACGCTCCGCTGCCGGCATGGGTGCTGAACGGCGCCGTGGCCGA
GAACGGTGGCGTGCATGGCGCGCAGGGTTCGTGGTCGCCGGCGGCCAGTGCATTCGTCAAGCGTGCCGAATTGCCGGTGT
ACCAGCGCCAGGTGTTCCGTGCCGCGCTGAAGGGTACCGACTCGCCCGATCCGCGCCGTGCCGGCAAAACGATCGAGGAG
AACGATGGCGCGCGCATCTGGACCACTGATGGTGCCGACGATGTGCTCGTGATCTCGTTCAAGAGCAAGATGAACACGGT
TGGCCCAGATGTGCTCGATACCATCGTGCGCGCCGTGGAACTGGCCGAAGCCAGCTACAAGGGTCTGGTGGTGTGGCAAC
CGACGTCGCTGCAACTGGGCGCGCCGGGTGGTCCATTCTCGGCGGGCGCCAACCTGGAAGCCGCGATGCCGGCCTTCATG
ATGGGCGGTGCCAAGGGCATCGAGCCGTTCGTCAAGAAGTTCCAGGACACGATGATGCGCGTGAAGTACGCGGCGGTGCC
GGTGGTGCCGGCCGTGTCGGGCATCGCGCTCGGCGGTGGCTGCGAACTGATGCTGCATTCCGCGAAGCGGGTGGTGGCGC
TGGAAAGCTATGTCGGTCTCGTCGAGGTGGGCGTGGGTCTGGTGCCGGCCGGCGGTGGCCTCAAGGAAGCCGCGATCGCA
GCAGCCAAGGCCGCGCAGGCAGCGGGCAGCACGAACTACCTGAACTTCATCACCAATCGCTTCCAGGCAGCGGCGATGGC
CAAGGTGTCGTCGTCGGCGCTCGACGCGCAGAAGATCGGCTACGTCCAGCCGACCGACACGATCGTCTATAACGTCCATG
AACTGCTGTACGTGGCGCAGAACGAAGTGCGCGCGCTGGCCAACGCCGGCTATCGCGCACCGCTGCCCGGCCAGCTGATT
CCGGTGGCTGGCCGCTCGGGCATCGCCACGATCAAGGCATCGCTGGTCAACATGCGCGACGGCAACTTCATCTCGGCGCA
CGACTTCCTGATTGCCTCGCGCATCGCGGAAGTGGTTTGCGGCGGCGATGTGGAGGCCGGCTCGCTGGTCAGCGAAGACT
GGCTGCTGGCGCTGGAGCGTCGCGCATTCATCGACCTGCTGGGCAACGGCAAGACCCAGGAGCGGATCATGGGAATGCTG
CAGACGGGCAAGCCGGTGCGCAACTAA

Upstream 100 bases:

>100_bases
CCTGAGGGTTGTCTCCCTTCTCCCCTGATACGGGAGAAGGGGAGAATCCACCCGCAGCATATTCATCTCTCCTCAAACGC
TCACTAGCCAAGGAGCGCGC

Downstream 100 bases:

>100_bases
TCAGGCCAACGAGGAACCGACATCATGAAACAACTGCAAGACGCATACATTGTCGCGGCTACCCGTTCGCCGATCGGCAA
GGCCCCGAAGGGCGCTTTCA

Product: putative 3-hydroxyacyl-coa dehydrogenase oxidoreductase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 808; Mature: 807

Protein sequence:

>808_residues
MSNFIVKKVAVLGAGVMGAQIAAHLINARVPVILFDLPAKEGPKNGIADRAIENLKKLSPAPLGIKEEAGLIRAANYEDD
IALLKECDVVIEAIAERMDWKHDLYKKVSPHLAPNAIFATNTSGLSITALSDGFDADLKSRFCGVHFFNPPRYMHLVELI
PTATTKPEILDRLESFLTTSLGKGVVRAKDTSNFIANRVGIFSILAVFAEAEKFGIPFDIVDDLTGTKLGRAKSATFRTA
DVVGLDTMAHVIKTMQDNLTDDPFAPVYKTPAVLKGLVDAGALGQKTGAGFYKKEGKAIKVLDAKSGQYVESGKKADEIV
VRILKKEPAERIKLLRESTNPQAQFLWGVFRDVFHYIAVYLEQIAGSAADIDLAIRWGFGWNSGPFEDWQAAGWKQVAEW
VKEDVEAGKALSNAPLPAWVLNGAVAENGGVHGAQGSWSPAASAFVKRAELPVYQRQVFRAALKGTDSPDPRRAGKTIEE
NDGARIWTTDGADDVLVISFKSKMNTVGPDVLDTIVRAVELAEASYKGLVVWQPTSLQLGAPGGPFSAGANLEAAMPAFM
MGGAKGIEPFVKKFQDTMMRVKYAAVPVVPAVSGIALGGGCELMLHSAKRVVALESYVGLVEVGVGLVPAGGGLKEAAIA
AAKAAQAAGSTNYLNFITNRFQAAAMAKVSSSALDAQKIGYVQPTDTIVYNVHELLYVAQNEVRALANAGYRAPLPGQLI
PVAGRSGIATIKASLVNMRDGNFISAHDFLIASRIAEVVCGGDVEAGSLVSEDWLLALERRAFIDLLGNGKTQERIMGML
QTGKPVRN

Sequences:

>Translated_808_residues
MSNFIVKKVAVLGAGVMGAQIAAHLINARVPVILFDLPAKEGPKNGIADRAIENLKKLSPAPLGIKEEAGLIRAANYEDD
IALLKECDVVIEAIAERMDWKHDLYKKVSPHLAPNAIFATNTSGLSITALSDGFDADLKSRFCGVHFFNPPRYMHLVELI
PTATTKPEILDRLESFLTTSLGKGVVRAKDTSNFIANRVGIFSILAVFAEAEKFGIPFDIVDDLTGTKLGRAKSATFRTA
DVVGLDTMAHVIKTMQDNLTDDPFAPVYKTPAVLKGLVDAGALGQKTGAGFYKKEGKAIKVLDAKSGQYVESGKKADEIV
VRILKKEPAERIKLLRESTNPQAQFLWGVFRDVFHYIAVYLEQIAGSAADIDLAIRWGFGWNSGPFEDWQAAGWKQVAEW
VKEDVEAGKALSNAPLPAWVLNGAVAENGGVHGAQGSWSPAASAFVKRAELPVYQRQVFRAALKGTDSPDPRRAGKTIEE
NDGARIWTTDGADDVLVISFKSKMNTVGPDVLDTIVRAVELAEASYKGLVVWQPTSLQLGAPGGPFSAGANLEAAMPAFM
MGGAKGIEPFVKKFQDTMMRVKYAAVPVVPAVSGIALGGGCELMLHSAKRVVALESYVGLVEVGVGLVPAGGGLKEAAIA
AAKAAQAAGSTNYLNFITNRFQAAAMAKVSSSALDAQKIGYVQPTDTIVYNVHELLYVAQNEVRALANAGYRAPLPGQLI
PVAGRSGIATIKASLVNMRDGNFISAHDFLIASRIAEVVCGGDVEAGSLVSEDWLLALERRAFIDLLGNGKTQERIMGML
QTGKPVRN
>Mature_807_residues
SNFIVKKVAVLGAGVMGAQIAAHLINARVPVILFDLPAKEGPKNGIADRAIENLKKLSPAPLGIKEEAGLIRAANYEDDI
ALLKECDVVIEAIAERMDWKHDLYKKVSPHLAPNAIFATNTSGLSITALSDGFDADLKSRFCGVHFFNPPRYMHLVELIP
TATTKPEILDRLESFLTTSLGKGVVRAKDTSNFIANRVGIFSILAVFAEAEKFGIPFDIVDDLTGTKLGRAKSATFRTAD
VVGLDTMAHVIKTMQDNLTDDPFAPVYKTPAVLKGLVDAGALGQKTGAGFYKKEGKAIKVLDAKSGQYVESGKKADEIVV
RILKKEPAERIKLLRESTNPQAQFLWGVFRDVFHYIAVYLEQIAGSAADIDLAIRWGFGWNSGPFEDWQAAGWKQVAEWV
KEDVEAGKALSNAPLPAWVLNGAVAENGGVHGAQGSWSPAASAFVKRAELPVYQRQVFRAALKGTDSPDPRRAGKTIEEN
DGARIWTTDGADDVLVISFKSKMNTVGPDVLDTIVRAVELAEASYKGLVVWQPTSLQLGAPGGPFSAGANLEAAMPAFMM
GGAKGIEPFVKKFQDTMMRVKYAAVPVVPAVSGIALGGGCELMLHSAKRVVALESYVGLVEVGVGLVPAGGGLKEAAIAA
AKAAQAAGSTNYLNFITNRFQAAAMAKVSSSALDAQKIGYVQPTDTIVYNVHELLYVAQNEVRALANAGYRAPLPGQLIP
VAGRSGIATIKASLVNMRDGNFISAHDFLIASRIAEVVCGGDVEAGSLVSEDWLLALERRAFIDLLGNGKTQERIMGMLQ
TGKPVRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=301, Percent_Identity=33.5548172757475, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI296179427, Length=316, Percent_Identity=32.5949367088608, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI261878539, Length=400, Percent_Identity=26, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI68989263, Length=400, Percent_Identity=26, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI20127408, Length=406, Percent_Identity=26.3546798029557, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1787661, Length=462, Percent_Identity=26.4069264069264, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790281, Length=333, Percent_Identity=26.1261261261261, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788682, Length=327, Percent_Identity=24.7706422018349, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17549919, Length=299, Percent_Identity=31.438127090301, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17563036, Length=294, Percent_Identity=30.2721088435374, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17553560, Length=300, Percent_Identity=29.6666666666667, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17558304, Length=397, Percent_Identity=27.9596977329975, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=388, Percent_Identity=29.3814432989691, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508953, Length=388, Percent_Identity=29.3814432989691, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144276, Length=291, Percent_Identity=31.9587628865979, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71985930, Length=416, Percent_Identity=24.0384615384615, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985923, Length=409, Percent_Identity=24.6943765281174, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549573, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921000, Length=402, Percent_Identity=26.3681592039801, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583077, Length=402, Percent_Identity=26.3681592039801, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24583079, Length=402, Percent_Identity=26.3681592039801, Blast_Score=76, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 86380; Mature: 86249

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFIVKKVAVLGAGVMGAQIAAHLINARVPVILFDLPAKEGPKNGIADRAIENLKKLSP
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCC
APLGIKEEAGLIRAANYEDDIALLKECDVVIEAIAERMDWKHDLYKKVSPHLAPNAIFAT
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEE
NTSGLSITALSDGFDADLKSRFCGVHFFNPPRYMHLVELIPTATTKPEILDRLESFLTTS
CCCCEEEEEECCCCCHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LGKGVVRAKDTSNFIANRVGIFSILAVFAEAEKFGIPFDIVDDLTGTKLGRAKSATFRTA
HCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCEEHH
DVVGLDTMAHVIKTMQDNLTDDPFAPVYKTPAVLKGLVDAGALGQKTGAGFYKKEGKAIK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEE
VLDAKSGQYVESGKKADEIVVRILKKEPAERIKLLRESTNPQAQFLWGVFRDVFHYIAVY
EEECCCCCHHHCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LEQIAGSAADIDLAIRWGFGWNSGPFEDWQAAGWKQVAEWVKEDVEAGKALSNAPLPAWV
HHHHCCCCCCEEEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCHHHCCCCCCHHH
LNGAVAENGGVHGAQGSWSPAASAFVKRAELPVYQRQVFRAALKGTDSPDPRRAGKTIEE
HCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCC
NDGARIWTTDGADDVLVISFKSKMNTVGPDVLDTIVRAVELAEASYKGLVVWQPTSLQLG
CCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEC
APGGPFSAGANLEAAMPAFMMGGAKGIEPFVKKFQDTMMRVKYAAVPVVPAVSGIALGGG
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCC
CELMLHSAKRVVALESYVGLVEVGVGLVPAGGGLKEAAIAAAKAAQAAGSTNYLNFITNR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
FQAAAMAKVSSSALDAQKIGYVQPTDTIVYNVHELLYVAQNEVRALANAGYRAPLPGQLI
HHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
PVAGRSGIATIKASLVNMRDGNFISAHDFLIASRIAEVVCGGDVEAGSLVSEDWLLALER
EECCCCCHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RAFIDLLGNGKTQERIMGMLQTGKPVRN
HHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNFIVKKVAVLGAGVMGAQIAAHLINARVPVILFDLPAKEGPKNGIADRAIENLKKLSP
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCC
APLGIKEEAGLIRAANYEDDIALLKECDVVIEAIAERMDWKHDLYKKVSPHLAPNAIFAT
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEE
NTSGLSITALSDGFDADLKSRFCGVHFFNPPRYMHLVELIPTATTKPEILDRLESFLTTS
CCCCEEEEEECCCCCHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LGKGVVRAKDTSNFIANRVGIFSILAVFAEAEKFGIPFDIVDDLTGTKLGRAKSATFRTA
HCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCEEHH
DVVGLDTMAHVIKTMQDNLTDDPFAPVYKTPAVLKGLVDAGALGQKTGAGFYKKEGKAIK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEE
VLDAKSGQYVESGKKADEIVVRILKKEPAERIKLLRESTNPQAQFLWGVFRDVFHYIAVY
EEECCCCCHHHCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LEQIAGSAADIDLAIRWGFGWNSGPFEDWQAAGWKQVAEWVKEDVEAGKALSNAPLPAWV
HHHHCCCCCCEEEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCHHHCCCCCCHHH
LNGAVAENGGVHGAQGSWSPAASAFVKRAELPVYQRQVFRAALKGTDSPDPRRAGKTIEE
HCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCC
NDGARIWTTDGADDVLVISFKSKMNTVGPDVLDTIVRAVELAEASYKGLVVWQPTSLQLG
CCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEC
APGGPFSAGANLEAAMPAFMMGGAKGIEPFVKKFQDTMMRVKYAAVPVVPAVSGIALGGG
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCC
CELMLHSAKRVVALESYVGLVEVGVGLVPAGGGLKEAAIAAAKAAQAAGSTNYLNFITNR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
FQAAAMAKVSSSALDAQKIGYVQPTDTIVYNVHELLYVAQNEVRALANAGYRAPLPGQLI
HHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
PVAGRSGIATIKASLVNMRDGNFISAHDFLIASRIAEVVCGGDVEAGSLVSEDWLLALER
EECCCCCHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RAFIDLLGNGKTQERIMGMLQTGKPVRN
HHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]