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The map label for this gene is ybhO [H]

Identifier: 94309328

GI number: 94309328

Start: 408002

End: 409387

Strand: Direct

Name: ybhO [H]

Synonym: Rmet_0383

Alternate gene names: 94309328

Gene position: 408002-409387 (Clockwise)

Preceding gene: 94309326

Following gene: 94309329

Centisome position: 10.39

GC content: 66.23

Gene sequence:

>1386_bases
ATGTGCAGGAGCCGCCCGTTCGCCGATAATCGAGCCATGTCACGGATCAACGATCGGGTATCGCCCCCAACGTCGAGTGC
GCCAGGCACGCCGGAATCGCCATCGAGCGCATTGCATCAAGAGGTTGGCGATCCCGCTGCCACCACCGTTGCCAACGCCA
CTGCGCCATTGATGCGCTGGGTGCGCCGGCGCGGCAGCCCGGTCCAGGGCAACCTGGTCGATCTGCTGAGCAACGGCCAG
GAGTATTTTCCCGCCCTGATCGAGGCGATTGATGCCGCGCGCGTGCACGTCGTGCTCGAGACCTATATTTATGCCGACGA
TGATGTCGGCGCCCTTGTTACTGATGCGTTGATCCGGGCGGCGCAACGCGGTGTGGATGTCAGGCTGGTCGTCGACGGAT
TCGGCGCGGGGGATCTGCCTGCGACGCTCGCCAGCCGGCTGCGCGATGGAGGTGTGCGCCTCGAGGTTTTTCGTCCGGTG
CGTGGATTCAGGCTGGCGCGCCGGCATCTGCGGCGGTTGCATCGCAAGATGGCGGTGATCGACGACAGCGTGGCCTTCGT
CGGTGGTATCAATATCATCGACGACCACAACTACGGCCCGCTGGAATTGCCCGAAGTCGGCCCACGCTACGACTTTGCCG
TGCGCGTGCGCGGCCCGCTGGTGGCGCAGATCGCGCTCGCTTCGGCGCGGCTGTGGTTCCGGATGGCACAGCAACGCGGG
CTGCGCGAAACCGCAACGGCTTTCACCGAAGTGGAAACGCTGACCACCGCCGCGCGGCAGGCCCGGCGCGAGCATCACGC
GGGCGGCGTGGCTGCGGCATTGCTGCTGCGCGACAACCTGCGCAATCGCCGCACGATCGAGCGCGAATATCTCTACGCGC
TGGGCGCCGCGCGTCATGACGTGATCATCGCCAACGCCTATTTTCTGCCTGGCACGAAGATGCGGCGCGCGTTGCTGGCG
TGCCGTGAGCGCGGGGTGCGTGTGCGACTGCTGCTGCAGGGGATGGTCGAGTACCGGCTGCAACATTTCGCGACGCACGC
GCTCTATGCGCGGCTGCTCGAGGCCGGCATCGAAATCTACGAATACGAGGCGAGCTTCCTGCACGCGAAGGTCGCCGTCA
TCGACAACTCGTGGGCGACGGTCGGCTCGAGCAACCTGGATCCGTTCAGCCTGCTGCTGGCACGAGAGGCCAATGTCGCG
GTGTATGACCCGAGCTTTGCCGGCGTGCTGCGCGCGCGTCTGGAGCGGGCCATGGCGCAGCGCAGCGCGCGCGTGGTGCC
CGAGGTTCACGCACGCCTGCCGCGACTGCGCCGGTTTGCCAATTGGGCGGCGTACTACGTGTTGCGTCTCGGCGTCGTGA
TCGCGGGTGTCACAGGCCGTTACTGA

Upstream 100 bases:

>100_bases
TCTTGCCGCTGCCCGACGAGCCGGCGATACCGAATACCTTCACAATGCTTTCCCTGTTGGGCGTCACAATGCTCCGACAA
TATCAGACTTCGCCAGGGCC

Downstream 100 bases:

>100_bases
CGCCGCGCAAGCCGGGCACGGTAACATGCTGCCCTGCCGCAAGCCGCGCCTTCCGCGCAAACGTGCCCCGGCCATTTCAA
GCCGGTTTTAAGCCGATGCT

Product: putative phospholipase d/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MCRSRPFADNRAMSRINDRVSPPTSSAPGTPESPSSALHQEVGDPAATTVANATAPLMRWVRRRGSPVQGNLVDLLSNGQ
EYFPALIEAIDAARVHVVLETYIYADDDVGALVTDALIRAAQRGVDVRLVVDGFGAGDLPATLASRLRDGGVRLEVFRPV
RGFRLARRHLRRLHRKMAVIDDSVAFVGGINIIDDHNYGPLELPEVGPRYDFAVRVRGPLVAQIALASARLWFRMAQQRG
LRETATAFTEVETLTTAARQARREHHAGGVAAALLLRDNLRNRRTIEREYLYALGAARHDVIIANAYFLPGTKMRRALLA
CRERGVRVRLLLQGMVEYRLQHFATHALYARLLEAGIEIYEYEASFLHAKVAVIDNSWATVGSSNLDPFSLLLAREANVA
VYDPSFAGVLRARLERAMAQRSARVVPEVHARLPRLRRFANWAAYYVLRLGVVIAGVTGRY

Sequences:

>Translated_461_residues
MCRSRPFADNRAMSRINDRVSPPTSSAPGTPESPSSALHQEVGDPAATTVANATAPLMRWVRRRGSPVQGNLVDLLSNGQ
EYFPALIEAIDAARVHVVLETYIYADDDVGALVTDALIRAAQRGVDVRLVVDGFGAGDLPATLASRLRDGGVRLEVFRPV
RGFRLARRHLRRLHRKMAVIDDSVAFVGGINIIDDHNYGPLELPEVGPRYDFAVRVRGPLVAQIALASARLWFRMAQQRG
LRETATAFTEVETLTTAARQARREHHAGGVAAALLLRDNLRNRRTIEREYLYALGAARHDVIIANAYFLPGTKMRRALLA
CRERGVRVRLLLQGMVEYRLQHFATHALYARLLEAGIEIYEYEASFLHAKVAVIDNSWATVGSSNLDPFSLLLAREANVA
VYDPSFAGVLRARLERAMAQRSARVVPEVHARLPRLRRFANWAAYYVLRLGVVIAGVTGRY
>Mature_461_residues
MCRSRPFADNRAMSRINDRVSPPTSSAPGTPESPSSALHQEVGDPAATTVANATAPLMRWVRRRGSPVQGNLVDLLSNGQ
EYFPALIEAIDAARVHVVLETYIYADDDVGALVTDALIRAAQRGVDVRLVVDGFGAGDLPATLASRLRDGGVRLEVFRPV
RGFRLARRHLRRLHRKMAVIDDSVAFVGGINIIDDHNYGPLELPEVGPRYDFAVRVRGPLVAQIALASARLWFRMAQQRG
LRETATAFTEVETLTTAARQARREHHAGGVAAALLLRDNLRNRRTIEREYLYALGAARHDVIIANAYFLPGTKMRRALLA
CRERGVRVRLLLQGMVEYRLQHFATHALYARLLEAGIEIYEYEASFLHAKVAVIDNSWATVGSSNLDPFSLLLAREANVA
VYDPSFAGVLRARLERAMAQRSARVVPEVHARLPRLRRFANWAAYYVLRLGVVIAGVTGRY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=367, Percent_Identity=38.9645776566758, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1787502, Length=369, Percent_Identity=27.3712737127371, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081826, Length=380, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 51152; Mature: 51152

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRSRPFADNRAMSRINDRVSPPTSSAPGTPESPSSALHQEVGDPAATTVANATAPLMRW
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
VRRRGSPVQGNLVDLLSNGQEYFPALIEAIDAARVHVVLETYIYADDDVGALVTDALIRA
HHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEHHEECCCCHHHHHHHHHHHH
AQRGVDVRLVVDGFGAGDLPATLASRLRDGGVRLEVFRPVRGFRLARRHLRRLHRKMAVI
HHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
DDSVAFVGGINIIDDHNYGPLELPEVGPRYDFAVRVRGPLVAQIALASARLWFRMAQQRG
CCCHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC
LRETATAFTEVETLTTAARQARREHHAGGVAAALLLRDNLRNRRTIEREYLYALGAARHD
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIIANAYFLPGTKMRRALLACRERGVRVRLLLQGMVEYRLQHFATHALYARLLEAGIEIY
EEEEEEEECCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EYEASFLHAKVAVIDNSWATVGSSNLDPFSLLLAREANVAVYDPSFAGVLRARLERAMAQ
EEHHHHHEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHH
RSARVVPEVHARLPRLRRFANWAAYYVLRLGVVIAGVTGRY
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MCRSRPFADNRAMSRINDRVSPPTSSAPGTPESPSSALHQEVGDPAATTVANATAPLMRW
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
VRRRGSPVQGNLVDLLSNGQEYFPALIEAIDAARVHVVLETYIYADDDVGALVTDALIRA
HHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEHHEECCCCHHHHHHHHHHHH
AQRGVDVRLVVDGFGAGDLPATLASRLRDGGVRLEVFRPVRGFRLARRHLRRLHRKMAVI
HHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
DDSVAFVGGINIIDDHNYGPLELPEVGPRYDFAVRVRGPLVAQIALASARLWFRMAQQRG
CCCHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC
LRETATAFTEVETLTTAARQARREHHAGGVAAALLLRDNLRNRRTIEREYLYALGAARHD
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIIANAYFLPGTKMRRALLACRERGVRVRLLLQGMVEYRLQHFATHALYARLLEAGIEIY
EEEEEEEECCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EYEASFLHAKVAVIDNSWATVGSSNLDPFSLLLAREANVAVYDPSFAGVLRARLERAMAQ
EEHHHHHEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHH
RSARVVPEVHARLPRLRRFANWAAYYVLRLGVVIAGVTGRY
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]