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The map label for this gene is coxC [H]

Identifier: 94309210

GI number: 94309210

Start: 282495

End: 283355

Strand: Direct

Name: coxC [H]

Synonym: Rmet_0265

Alternate gene names: 94309210

Gene position: 282495-283355 (Clockwise)

Preceding gene: 94309209

Following gene: 94309212

Centisome position: 7.19

GC content: 63.53

Gene sequence:

>861_bases
ATGAGTGCGAATCGCGCAAACGCCCCGTACTACTTCGTGCCGGGCCCGTCGCGCCATCCGATCACGGCGGCATTCGGCCT
GCTGATGACCGGCGCGGGAGCCGCGGGTTGGGTCAACGGGCAGCCGTGGGCGCCGTACCTGTGCGGCTTCGGCCTGTTGT
GGTTCCTCTTCGTGCTCAAGAGCTGGTTCGGTGACGCCATCCGCGAATCCGAAGGCGGCATGTACGGCAAGAACATCGAC
ACCTCGTTCCGCTGGTCGATGGGCTGGTTCATCTTCTCCGAAGTGATGTTCTTCGCGGCGTTCTTCGGCGCCCTGTTCTA
CGCGCGCACCATCGCCATGCCGTGGCTGGGCGACCTGAACAACAAGATCATCTGGCCGGACTTCGCGGCCGTGTGGCCGA
ACATGGGCCCTGCCGGCACCGTGGAAGACTTCCAGACGATGGGCCCGTGGCCGATCCCGACCATCAACACGGCGCTGCTG
CTGACCTCGGGCGTCACGCTGACCTGGGCGCACCACGCGCTGCTGGCCGGCAAGCGCAGCCAGCTGATTCAGGGCCTGGT
CCTGACGATCCTGCTGGGCGCGATCTTCATGTGCCTGCAGGCCTACGAGTACATGCACGCCTACAGCGAACTGAACCTGA
AGCTGACCTCGGGTGTCTATGGTTCGACGTTCTTCCTGCTCACGGGATTCCACGGCTTTCACGTGACGATGGGCGCGATC
ATGCTGACGGTGGTGCTGATCCGCGTGCTGAAGGGCCATTTCACGCCGGAGCATCACTTCGCATTCGAAGGTGCAGCCTG
GTACTGGCACTTCGTGGACGTGGTCTGGCTGGGCCTGTACGTGGTGGTCTACTGGCTGTAA

Upstream 100 bases:

>100_bases
TAGCAGGAAACTAGCAGGGAAAAAGGACAGAGCCGCTGGCAACCGAAGCGAAGCGGATCTGGCGAATAACCATTAGAGAC
TCTGAGCTGGAGATAGAAGA

Downstream 100 bases:

>100_bases
GGATTTCGCCGCGCCGCCTGCGGGCGGCGTGCGGTATCGAAGAAAGCGAAGCGCCGCGGGAGAGAAATCTCGGCGGCGCT
TTTTTTCGCGAGGATGCCTG

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSANRANAPYYFVPGPSRHPITAAFGLLMTGAGAAGWVNGQPWAPYLCGFGLLWFLFVLKSWFGDAIRESEGGMYGKNID
TSFRWSMGWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKIIWPDFAAVWPNMGPAGTVEDFQTMGPWPIPTINTALL
LTSGVTLTWAHHALLAGKRSQLIQGLVLTILLGAIFMCLQAYEYMHAYSELNLKLTSGVYGSTFFLLTGFHGFHVTMGAI
MLTVVLIRVLKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Sequences:

>Translated_286_residues
MSANRANAPYYFVPGPSRHPITAAFGLLMTGAGAAGWVNGQPWAPYLCGFGLLWFLFVLKSWFGDAIRESEGGMYGKNID
TSFRWSMGWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKIIWPDFAAVWPNMGPAGTVEDFQTMGPWPIPTINTALL
LTSGVTLTWAHHALLAGKRSQLIQGLVLTILLGAIFMCLQAYEYMHAYSELNLKLTSGVYGSTFFLLTGFHGFHVTMGAI
MLTVVLIRVLKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
>Mature_285_residues
SANRANAPYYFVPGPSRHPITAAFGLLMTGAGAAGWVNGQPWAPYLCGFGLLWFLFVLKSWFGDAIRESEGGMYGKNIDT
SFRWSMGWFIFSEVMFFAAFFGALFYARTIAMPWLGDLNNKIIWPDFAAVWPNMGPAGTVEDFQTMGPWPIPTINTALLL
TSGVTLTWAHHALLAGKRSQLIQGLVLTILLGAIFMCLQAYEYMHAYSELNLKLTSGVYGSTFFLLTGFHGFHVTMGAIM
LTVVLIRVLKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=276, Percent_Identity=42.3913043478261, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1786633, Length=151, Percent_Identity=33.7748344370861, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6226542, Length=292, Percent_Identity=34.2465753424658, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32054; Mature: 31923

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANRANAPYYFVPGPSRHPITAAFGLLMTGAGAAGWVNGQPWAPYLCGFGLLWFLFVLK
CCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SWFGDAIRESEGGMYGKNIDTSFRWSMGWFIFSEVMFFAAFFGALFYARTIAMPWLGDLN
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NKIIWPDFAAVWPNMGPAGTVEDFQTMGPWPIPTINTALLLTSGVTLTWAHHALLAGKRS
CCEECCCHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHH
QLIQGLVLTILLGAIFMCLQAYEYMHAYSELNLKLTSGVYGSTFFLLTGFHGFHVTMGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHCCCHHHHHHHHH
MLTVVLIRVLKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SANRANAPYYFVPGPSRHPITAAFGLLMTGAGAAGWVNGQPWAPYLCGFGLLWFLFVLK
CCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SWFGDAIRESEGGMYGKNIDTSFRWSMGWFIFSEVMFFAAFFGALFYARTIAMPWLGDLN
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NKIIWPDFAAVWPNMGPAGTVEDFQTMGPWPIPTINTALLLTSGVTLTWAHHALLAGKRS
CCEECCCHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHH
QLIQGLVLTILLGAIFMCLQAYEYMHAYSELNLKLTSGVYGSTFFLLTGFHGFHVTMGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHCCCHHHHHHHHH
MLTVVLIRVLKGHFTPEHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]