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The map label for this gene is hit [H]

Identifier: 94309156

GI number: 94309156

Start: 224403

End: 224840

Strand: Direct

Name: hit [H]

Synonym: Rmet_0211

Alternate gene names: 94309156

Gene position: 224403-224840 (Clockwise)

Preceding gene: 94309155

Following gene: 94309157

Centisome position: 5.71

GC content: 65.3

Gene sequence:

>438_bases
ATGCAGGCCGAGTACGACAGCAACAACATCTTCGCGCGCATCCTGCGCGGCGAACTCCCGTGCTTCAAGGTTTATGAAGA
CGCGGACACGATTGCGTTCATGGACATCATGCCGCAATCAGACGGTCACACACTAGTGGTGCCGAAGGAGCAGGCCGTCG
ACGTGTTCGGCCTGTCCGAGGCCGGCGCGGCCGCGGCGATCCGTGCGACGCAGATCGTCGCGCGTGGCGTGCGCGAGGCC
TTCCAGCCCGATGGCGTGGTGATCAGCCAGTTCAATGGCGCAGCGGCCGGCCAGACCGTGCCGCACATCCACTTTCATAT
CGTGCCGCGCTACGTGGACCAGCCGCTGCGCGGCCATGCACGCCAGCAACAGGACATGGGCGTGCTCAAGCAGCACGCCG
AGCGCGTCATTGCCGCGCTGGCGAAGCTCAAGGGCTGA

Upstream 100 bases:

>100_bases
GCAATATGTAATTGCGTCGATGGAAATAATGGGTGGGGCGGTTCACGGCGGCGGACGCTGGGGCTACACTCAGCGTTCCG
CTTGAAAAACCGAGACACCC

Downstream 100 bases:

>100_bases
GCGCGCCCGAAAATCGAATCACCAAACAACTGGAAACTGAAGGAAGGAAGACAGACATGGCAATCAAGACAGTGGGCATC
GTTGGTGCCGGCACGATGGG

Product: diadenosine tetraphosphate (Ap4A) hydrolase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MQAEYDSNNIFARILRGELPCFKVYEDADTIAFMDIMPQSDGHTLVVPKEQAVDVFGLSEAGAAAAIRATQIVARGVREA
FQPDGVVISQFNGAAAGQTVPHIHFHIVPRYVDQPLRGHARQQQDMGVLKQHAERVIAALAKLKG

Sequences:

>Translated_145_residues
MQAEYDSNNIFARILRGELPCFKVYEDADTIAFMDIMPQSDGHTLVVPKEQAVDVFGLSEAGAAAAIRATQIVARGVREA
FQPDGVVISQFNGAAAGQTVPHIHFHIVPRYVDQPLRGHARQQQDMGVLKQHAERVIAALAKLKG
>Mature_145_residues
MQAEYDSNNIFARILRGELPCFKVYEDADTIAFMDIMPQSDGHTLVVPKEQAVDVFGLSEAGAAAAIRATQIVARGVREA
FQPDGVVISQFNGAAAGQTVPHIHFHIVPRYVDQPLRGHARQQQDMGVLKQHAERVIAALAKLKG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320078, Length=146, Percent_Identity=32.1917808219178, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581222, Length=102, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28574010, Length=102, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15832; Mature: 15832

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAEYDSNNIFARILRGELPCFKVYEDADTIAFMDIMPQSDGHTLVVPKEQAVDVFGLSE
CCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCEEEECHHHCCEEECCCC
AGAAAAIRATQIVARGVREAFQPDGVVISQFNGAAAGQTVPHIHFHIVPRYVDQPLRGHA
CCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEECHHHCCCHHHHH
RQQQDMGVLKQHAERVIAALAKLKG
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQAEYDSNNIFARILRGELPCFKVYEDADTIAFMDIMPQSDGHTLVVPKEQAVDVFGLSE
CCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCEEEECHHHCCEEECCCC
AGAAAAIRATQIVARGVREAFQPDGVVISQFNGAAAGQTVPHIHFHIVPRYVDQPLRGHA
CCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEECHHHCCCHHHHH
RQQQDMGVLKQHAERVIAALAKLKG
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]