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The map label for this gene is regA [H]

Identifier: 94309080

GI number: 94309080

Start: 140454

End: 141017

Strand: Reverse

Name: regA [H]

Synonym: Rmet_0135

Alternate gene names: 94309080

Gene position: 141017-140454 (Counterclockwise)

Preceding gene: 94309081

Following gene: 94309078

Centisome position: 3.59

GC content: 66.84

Gene sequence:

>564_bases
ATGCCCTTCCTCGTCATCGATGACGACGAAGTTTTTTCCGGCACCCTGGCCCGCGCCCTCACGCGCCGCGGCTATGCCGT
GCAGGTCGCCCATAACGGCGCCGAAGCGCTGGCCCTGGCCGGCAGGACACCATTCGCCTACGTCACGCTGGATCTGCATC
TGGGACCGCCGCCGGAGTCGGGCGGCACGTCAGCCTCGGAATCGGGATTGCATCTGGTGGCGCCGCTGCGCGCGGCGTTG
CCCGATGCGCGCATCCTGGTGCTGACCGGCTACGCAAGCATCGCCACGGCCGTGGCCGCGGTCAAACAAGGGGCTGATGA
GTATCTGGCCAAGCCGGCCAATGTCGACTCGATCCTGACCGCGCTGATGGCGGGTGTTTCCGAGGATGCGGCCGAGGCCG
CGCTGGAGGAACCGGTGCCGCTATCGGTGGCACGGCTCGAATGGGAGCATATTCAACGTGTGCTCACCGAGCATGGGGGC
AATATCTCGGCCACGGCGCGCGCGCTGAATATGCATCGGCGCACCTTGCAGCGCAAGCTGGGCAAGCGGCCGGTTTCACG
CTGA

Upstream 100 bases:

>100_bases
TCGAACTTCGCCTTCCGCTCACGGCCGCATCCGAACGCGCCATCGCCGCACAACCCGACTTCCAACCGTGATGACCGACG
TCACCGCCTCCAACGACGCC

Downstream 100 bases:

>100_bases
ATCCGGCCGGCTCGCGCCAGCCGCGCGGCCATCGCACTGGCTCACAGGCGCAGCTGGACGTAATCCCAACCAAGATCGTC
GGCATCCGCCGACGCAGACG

Product: RegA, response regulator containing a Fis-type DNA-binding domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPFLVIDDDEVFSGTLARALTRRGYAVQVAHNGAEALALAGRTPFAYVTLDLHLGPPPESGGTSASESGLHLVAPLRAAL
PDARILVLTGYASIATAVAAVKQGADEYLAKPANVDSILTALMAGVSEDAAEAALEEPVPLSVARLEWEHIQRVLTEHGG
NISATARALNMHRRTLQRKLGKRPVSR

Sequences:

>Translated_187_residues
MPFLVIDDDEVFSGTLARALTRRGYAVQVAHNGAEALALAGRTPFAYVTLDLHLGPPPESGGTSASESGLHLVAPLRAAL
PDARILVLTGYASIATAVAAVKQGADEYLAKPANVDSILTALMAGVSEDAAEAALEEPVPLSVARLEWEHIQRVLTEHGG
NISATARALNMHRRTLQRKLGKRPVSR
>Mature_186_residues
PFLVIDDDEVFSGTLARALTRRGYAVQVAHNGAEALALAGRTPFAYVTLDLHLGPPPESGGTSASESGLHLVAPLRAALP
DARILVLTGYASIATAVAAVKQGADEYLAKPANVDSILTALMAGVSEDAAEAALEEPVPLSVARLEWEHIQRVLTEHGGN
ISATARALNMHRRTLQRKLGKRPVSR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=146, Percent_Identity=30.1369863013699, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19747; Mature: 19616

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLVIDDDEVFSGTLARALTRRGYAVQVAHNGAEALALAGRTPFAYVTLDLHLGPPPES
CCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHEEECCCCCEEEEEEEEEECCCCCC
GGTSASESGLHLVAPLRAALPDARILVLTGYASIATAVAAVKQGADEYLAKPANVDSILT
CCCCCCCCCCEEEEHHHHHCCCCEEEEEECHHHHHHHHHHHHHCHHHHHCCCCCHHHHHH
ALMAGVSEDAAEAALEEPVPLSVARLEWEHIQRVLTEHGGNISATARALNMHRRTLQRKL
HHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKRPVSR
CCCCCCC
>Mature Secondary Structure 
PFLVIDDDEVFSGTLARALTRRGYAVQVAHNGAEALALAGRTPFAYVTLDLHLGPPPES
CEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHEEECCCCCEEEEEEEEEECCCCCC
GGTSASESGLHLVAPLRAALPDARILVLTGYASIATAVAAVKQGADEYLAKPANVDSILT
CCCCCCCCCCEEEEHHHHHCCCCEEEEEECHHHHHHHHHHHHHCHHHHHCCCCCHHHHHH
ALMAGVSEDAAEAALEEPVPLSVARLEWEHIQRVLTEHGGNISATARALNMHRRTLQRKL
HHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKRPVSR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA