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The map label for this gene is yjiA [H]

Identifier: 94309072

GI number: 94309072

Start: 133191

End: 134282

Strand: Reverse

Name: yjiA [H]

Synonym: Rmet_0127

Alternate gene names: 94309072

Gene position: 134282-133191 (Counterclockwise)

Preceding gene: 94309073

Following gene: 94309071

Centisome position: 3.42

GC content: 61.17

Gene sequence:

>1092_bases
ATGTCCAAACTGATTCCGGTCACGATCCTTACCGGCTTCCTCGGCAGCGGCAAGACCACGCTGCTCAAGCGTATCCTCAA
CGAGCAGCACGGCATGAAGATCGCCGTGATCGAAAACGAGTTCGGCGAAGAAAACATCGACAACGAGATCCTGGTGCAGG
ACGGCCGCGAGCAGATCGTGCAGATGAGCAACGGCTGCATTTGCTGCACGATCCGCGGCGATCTGGTGCAGGCGCTGTCC
GATCTGGTCACCCAGCGCGATGAAGGCAAGATCGCGTTCGATCGCGTGGTGATCGAAACCACGGGCGTGGCCAATCCGGG
CCCCGTGGCGCAGACGTTCTTCATGGACGAGGAAATCGCCTCGCGCTACCTGCTGGACGCCGTGATCACGCTGGTCGATG
CCAAGCACGCCAACCTGCAGCTCGACAAGCAGGAAGAAGCACAGCGCCAGGTGGGCTTTGCCGACGCCATCTTCATCACC
AAAGCCGACCTGGTGAGCGAAGCCGAGGTGGCGGATCTGCGTCATCGCCTGCTGCACATGAACCCGCGCGCGCCGATCAA
CGCCGCGCACTTCGGCGAAGCGCCGATCGACCTGATCTTTGACCTGCGCGGTTTCAACCTGAACGAAAAGCTCGAGATCG
ACCCAGATTTCCTGCGCGCCGACGAGCACGACCACGAACATGACCACGAACACGGCGAACACTGCGGCACCGATTGCGGT
CACGACCACGGCCATGAGCATGGCCACGATCACGGGCACGGCCACGCGCATGACCACCACCACCATCATCATCACACCGA
CCGGATCGCGTCGTTCGTCTTCCGCAGCGACAAGCCGTTCCATTACGGCAAGCTAGAGGAATTCCTGTCGGGCATCCTGT
CCGTGTACGGCGAGAAGCTGCTGCGCTACAAAGGCGTGCTCTATATGGAAGGCGTGGACCGCAAGGTGGTGTTCCAGGGC
GTGCACCAGCTTATGGGCAGCGATATCGGCGCCAAGTGGGAAGATGAACAACCGGGCACGAAGATGGTCTTCATTGGCGT
GGACCTGCCGCGCGACGCAATTCTGAAGGGACTTGCGGCCTGCCTCGCCTGA

Upstream 100 bases:

>100_bases
GCATCTGCGCCGAATGCGGCCGATCGCACGGCGACGCATCCGCGCACTGACACATCCAGACACCTTTAGACGGCGAGCCC
TTTTCTCGGAGTACCACAAC

Downstream 100 bases:

>100_bases
CTTTACGTTTAGTGCGCCATCAGACACCTGCGTAAATCCGGCCCGATAATCCCTCCCGAAAGGGGGTACAGGGAAAACTC
GTGGCTTTTGTCCGGTTTTC

Product: cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIVQMSNGCICCTIRGDLVQALS
DLVTQRDEGKIAFDRVVIETTGVANPGPVAQTFFMDEEIASRYLLDAVITLVDAKHANLQLDKQEEAQRQVGFADAIFIT
KADLVSEAEVADLRHRLLHMNPRAPINAAHFGEAPIDLIFDLRGFNLNEKLEIDPDFLRADEHDHEHDHEHGEHCGTDCG
HDHGHEHGHDHGHGHAHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILSVYGEKLLRYKGVLYMEGVDRKVVFQG
VHQLMGSDIGAKWEDEQPGTKMVFIGVDLPRDAILKGLAACLA

Sequences:

>Translated_363_residues
MSKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIVQMSNGCICCTIRGDLVQALS
DLVTQRDEGKIAFDRVVIETTGVANPGPVAQTFFMDEEIASRYLLDAVITLVDAKHANLQLDKQEEAQRQVGFADAIFIT
KADLVSEAEVADLRHRLLHMNPRAPINAAHFGEAPIDLIFDLRGFNLNEKLEIDPDFLRADEHDHEHDHEHGEHCGTDCG
HDHGHEHGHDHGHGHAHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILSVYGEKLLRYKGVLYMEGVDRKVVFQG
VHQLMGSDIGAKWEDEQPGTKMVFIGVDLPRDAILKGLAACLA
>Mature_362_residues
SKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIVQMSNGCICCTIRGDLVQALSD
LVTQRDEGKIAFDRVVIETTGVANPGPVAQTFFMDEEIASRYLLDAVITLVDAKHANLQLDKQEEAQRQVGFADAIFITK
ADLVSEAEVADLRHRLLHMNPRAPINAAHFGEAPIDLIFDLRGFNLNEKLEIDPDFLRADEHDHEHDHEHGEHCGTDCGH
DHGHEHGHDHGHGHAHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILSVYGEKLLRYKGVLYMEGVDRKVVFQGV
HQLMGSDIGAKWEDEQPGTKMVFIGVDLPRDAILKGLAACLA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=372, Percent_Identity=31.989247311828, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI126722884, Length=372, Percent_Identity=31.989247311828, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI146231952, Length=372, Percent_Identity=31.989247311828, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI148727351, Length=372, Percent_Identity=31.7204301075269, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI223941779, Length=187, Percent_Identity=43.8502673796791, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI223941776, Length=362, Percent_Identity=30.6629834254144, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI119120938, Length=210, Percent_Identity=34.7619047619048, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI87082430, Length=356, Percent_Identity=41.5730337078652, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1788499, Length=175, Percent_Identity=33.1428571428571, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324356, Length=227, Percent_Identity=32.5991189427313, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 40621; Mature: 40490

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIV
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHH
QMSNGCICCTIRGDLVQALSDLVTQRDEGKIAFDRVVIETTGVANPGPVAQTFFMDEEIA
HHCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
SRYLLDAVITLVDAKHANLQLDKQEEAQRQVGFADAIFITKADLVSEAEVADLRHRLLHM
HHHHHHHHHHHHCCCCCCCEECHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHHHHHCC
NPRAPINAAHFGEAPIDLIFDLRGFNLNEKLEIDPDFLRADEHDHEHDHEHGEHCGTDCG
CCCCCCCHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHCCCCCC
HDHGHEHGHDHGHGHAHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILSVYGEKL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LRYKGVLYMEGVDRKVVFQGVHQLMGSDIGAKWEDEQPGTKMVFIGVDLPRDAILKGLAA
HHHCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
CLA
HHC
>Mature Secondary Structure 
SKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIV
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHH
QMSNGCICCTIRGDLVQALSDLVTQRDEGKIAFDRVVIETTGVANPGPVAQTFFMDEEIA
HHCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
SRYLLDAVITLVDAKHANLQLDKQEEAQRQVGFADAIFITKADLVSEAEVADLRHRLLHM
HHHHHHHHHHHHCCCCCCCEECHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHHHHHCC
NPRAPINAAHFGEAPIDLIFDLRGFNLNEKLEIDPDFLRADEHDHEHDHEHGEHCGTDCG
CCCCCCCHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHCCCCCC
HDHGHEHGHDHGHGHAHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILSVYGEKL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LRYKGVLYMEGVDRKVVFQGVHQLMGSDIGAKWEDEQPGTKMVFIGVDLPRDAILKGLAA
HHHCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
CLA
HHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]