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The map label for this gene is minC

Identifier: 94308980

GI number: 94308980

Start: 37050

End: 37898

Strand: Reverse

Name: minC

Synonym: Rmet_0035

Alternate gene names: 94308980

Gene position: 37898-37050 (Counterclockwise)

Preceding gene: 94308991

Following gene: 94308979

Centisome position: 0.96

GC content: 67.02

Gene sequence:

>849_bases
ATGTCTCAGAAGAAATCGCCACGCTTCGAGCTGCGCAGTGGCAACGTCGACGCCCTCCTTCTCGCTCTCAATACCGCCGA
CCTGGACGCGGTGCGGGACGACCTCCTCTCCCGCTTCGAGTCAACCCCCGATTTCTTTTCTGATGACGTTGTCGCGCTGG
ACCTGCGCCGCCTGGAAGGCACCGGGGCGCTGGCGCTGGACCGTGTGATCGACACCCTGGCCACCCTCAAGGCCCGTGCC
ATCGGCGTGGTGGCCCGTGCCGACCAGCGCGACTGGGCCGGCGGCTTCGGCCTGCCGCTGCTGGACAGCCAGAGCCGGCG
TGGCGGCAAGGACGAGGCCCCTAAAGAGAAGGCGGGCAAACCCGAAGCCACGGCGGCAAGCGGGCAGACGGACGCCGAGG
CGGCCGGGAACACCGGCAAGGGCAAGGACAGCGAGGGCGCCGCCGTCAATGGCAAGGCCTCGGAAATCGCCGAGATCATG
GCGGCCGCGAACGCGGCTTCCGCCCCCCGCGCAATCCCCACGCTGCTGATCGACAAGCCGCTGCGCTCGGGCCAGCAGAT
CTACGCCCAGGGCGACGTGGTGATCCTGGACCTGGTCAGCTACGGCGCCGAAGTCATCGCCGAAGGCAATATCCATATCT
ATGCCCCGCTGCGCGGCCGCGCACTGGCGGGTGTCAAGGGTAATCCCGATGCGCGCATCTTCTGCACGTGCCTGGAGCCC
GAACTGATTTCCATCGCCGGCATCTACCGGACCGCGGAGCAGACACTCCCGGCCGACGTGCTCGGCAAGTCGGCACAGGT
TCGCCTGGCCGACGAAAAGCTGATCCTTGAACCGCTGCGCATGAAATAA

Upstream 100 bases:

>100_bases
CCGTGGTCCGCATCGGCCACCTGGGGCCGGCCGTCCGACATTTGTTACAGTTCCCCGGAGATACGACGTTAGAATGTGGC
ATTTCCACGGTCACCCGGCT

Downstream 100 bases:

>100_bases
CGGCAGCACGCAATCGAACGAATTCCACTCATACCGGACCATAGAGCCATGGCAAAAATCATCGTAGTGACCTCCGGCAA
GGGGGGCGTTGGCAAGACCA

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSQKKSPRFELRSGNVDALLLALNTADLDAVRDDLLSRFESTPDFFSDDVVALDLRRLEGTGALALDRVIDTLATLKARA
IGVVARADQRDWAGGFGLPLLDSQSRRGGKDEAPKEKAGKPEATAASGQTDAEAAGNTGKGKDSEGAAVNGKASEIAEIM
AAANAASAPRAIPTLLIDKPLRSGQQIYAQGDVVILDLVSYGAEVIAEGNIHIYAPLRGRALAGVKGNPDARIFCTCLEP
ELISIAGIYRTAEQTLPADVLGKSAQVRLADEKLILEPLRMK

Sequences:

>Translated_282_residues
MSQKKSPRFELRSGNVDALLLALNTADLDAVRDDLLSRFESTPDFFSDDVVALDLRRLEGTGALALDRVIDTLATLKARA
IGVVARADQRDWAGGFGLPLLDSQSRRGGKDEAPKEKAGKPEATAASGQTDAEAAGNTGKGKDSEGAAVNGKASEIAEIM
AAANAASAPRAIPTLLIDKPLRSGQQIYAQGDVVILDLVSYGAEVIAEGNIHIYAPLRGRALAGVKGNPDARIFCTCLEP
ELISIAGIYRTAEQTLPADVLGKSAQVRLADEKLILEPLRMK
>Mature_281_residues
SQKKSPRFELRSGNVDALLLALNTADLDAVRDDLLSRFESTPDFFSDDVVALDLRRLEGTGALALDRVIDTLATLKARAI
GVVARADQRDWAGGFGLPLLDSQSRRGGKDEAPKEKAGKPEATAASGQTDAEAAGNTGKGKDSEGAAVNGKASEIAEIMA
AANAASAPRAIPTLLIDKPLRSGQQIYAQGDVVILDLVSYGAEVIAEGNIHIYAPLRGRALAGVKGNPDARIFCTCLEPE
LISIAGIYRTAEQTLPADVLGKSAQVRLADEKLILEPLRMK

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=107, Percent_Identity=52.3364485981308, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_RALME (Q1LSF5)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_582190.1
- ProteinModelPortal:   Q1LSF5
- STRING:   Q1LSF5
- GeneID:   4036819
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_0035
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- ProtClustDB:   PRK01973
- BioCyc:   RMET266264:RMET_0035-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 29772; Mature: 29641

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKKSPRFELRSGNVDALLLALNTADLDAVRDDLLSRFESTPDFFSDDVVALDLRRLEG
CCCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
TGALALDRVIDTLATLKARAIGVVARADQRDWAGGFGLPLLDSQSRRGGKDEAPKEKAGK
CCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PEATAASGQTDAEAAGNTGKGKDSEGAAVNGKASEIAEIMAAANAASAPRAIPTLLIDKP
CCCCCCCCCCCHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCHHHHHHHCCC
LRSGQQIYAQGDVVILDLVSYGAEVIAEGNIHIYAPLRGRALAGVKGNPDARIFCTCLEP
CCCCCEEEECCCEEEEEHHHCCCEEEECCCEEEEECCCCCEEECCCCCCCCEEEEEECCC
ELISIAGIYRTAEQTLPADVLGKSAQVRLADEKLILEPLRMK
CHHHHHHHHHHHHHCCCHHHHCCCCEEEECCCHHHHCCCCCC
>Mature Secondary Structure 
SQKKSPRFELRSGNVDALLLALNTADLDAVRDDLLSRFESTPDFFSDDVVALDLRRLEG
CCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
TGALALDRVIDTLATLKARAIGVVARADQRDWAGGFGLPLLDSQSRRGGKDEAPKEKAGK
CCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PEATAASGQTDAEAAGNTGKGKDSEGAAVNGKASEIAEIMAAANAASAPRAIPTLLIDKP
CCCCCCCCCCCHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCHHHHHHHCCC
LRSGQQIYAQGDVVILDLVSYGAEVIAEGNIHIYAPLRGRALAGVKGNPDARIFCTCLEP
CCCCCEEEECCCEEEEEHHHCCCEEEECCCEEEEECCCCCEEECCCCCCCCEEEEEECCC
ELISIAGIYRTAEQTLPADVLGKSAQVRLADEKLILEPLRMK
CHHHHHHHHHHHHHCCCHHHHCCCCEEEECCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA