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The map label for this gene is pabB [H]

Identifier: 93007014

GI number: 93007014

Start: 2692505

End: 2694196

Strand: Direct

Name: pabB [H]

Synonym: Pcryo_2190

Alternate gene names: 93007014

Gene position: 2692505-2694196 (Clockwise)

Preceding gene: 93007013

Following gene: 93007023

Centisome position: 87.99

GC content: 42.38

Gene sequence:

>1692_bases
ATGGTTGTAATAGATACTCATACCACTGTGCAGACAGATTCTGCCCTACCGCCAGCTAGCAAAACTAGCTGGCGTTTTGG
TGACTTATCTGCTGCCGAATTAATGCCGCACCTGCAACGACATTTGTTAGAACAAAATAGCAAAGCAAACTGGCAGCTGG
TTTGGCTCAATAACGATGGGCGACCTGTGATTGGCTTATTACCAAAGACAAGCTGGTGCGTTTATCCTGTGACTAATAAC
ACGCTGCATGCTACTAAGCAGGGAAACCTTTGTAAAATCGAGAAAACACGGCGTGGGCATGTTCACCTTTATAGTAATTC
CAGTGATAGTGCGGCTACAAGCTATATGAGTTATAGCGACTGGCAAGAGGAATTAATTACTTACAGTCGGGCTCATGAAA
TAGATGGCATTCACGGTAACGGCTCGTTCTCAACTAAAGACGTCGATCAACAACCAAGTTATCAGCACGGCTTAATAGGT
TTTATCAGCTATGACATTAGTGCTCATGAACTCAGTCCAACCGTTAATATAGAGATGGCAGCACAGCCGTGCGCGTTATT
GGGGCATTATGATATTTACTTAACCGCTGATTCAGACAGTCAAAGCAGTTGGCAGTTAAAGGTAAATAATGATAATAACC
CTGACAGCAGCTCAGTCCAGCAGGATACAAATGCACTAATCAGAGTGCTAACATCTTATTTAAATAGTTTGGATAATCAA
CTATCGAATGAGAATGTCACTAAAAAATACTCCTGTAAAACGCCGCCTTTATTACTAGAAGCTCAATGGAGCAAACGACA
CTATCAGCAGGCATTTCATCAAACGCAAAATTATTTGCAGCAAGGCGATTGTTATCAAATCAATTTAACCCAAGCATGGA
GTGGCTATTTAAGCACTTATGAAGATAATTCAGTCACAAGCCTCATTGACTATTTACCTGCTTTGCACGCTAATACCCAA
GCGCCTTTTGCAGGATATATAGCCATTGATAGCTATAATCATGAAGGTAAAGTAAATACATCAAACCATCAGTTTGAATT
ATTAAGCTGTTCGCCGGAATTATTTTTTACCTTTAGCAAAGATATTGAGACTGACAAGCATCATATACGTACCAAGCCGA
TCAAAGGAACCATGCCGCGCGGCTTAACAACCGAACAAGATAATGACTATAAGCAGCAGTTAATCAACAGCGAAAAAGAC
CGTGCAGAAAACGTTATGATTGTGGATTTGTTACGTAATGATTTGGGTAAATACGCCAAAATCGGTAGCGTAAAGGTACC
ACAGCTATTTGCGATTGAGAGTTTTAGTAATGTACATCATATGGTCAGCACCATTACCGCCGAGCTCAAGACAGATACTC
ATCCCTTAAGCGTCTTATTTGGCAGTTTGCCTGCAGGATCAATTACTGGCACACCAAAGAAACGGGCGGTAGAGATTATT
GCAGAATTGGAAGGGGCACCGCGTAGTGCTTATTGTGGCACCATGGGTTATATGAACTTTGATGGTAGCGGTCAGTGGAA
TGTACTGATTCGCACACTGCAAGCGACCAGCACAGCTGACAATAGCAAACAAGTCAGTTTATGGGCAGGCGGAGGTATTA
CCGTTGCCTCTGACTGCGATGCTGAATATCAGGAGTGCCTAGATAAAGTCGGCAACCTATTATCTGTCCTTGCTAATACA
GCCAACCACTGA

Upstream 100 bases:

>100_bases
TGAAAAACGCGATCTTGAGCTTGAAACTCTTATGAGCAATAGCTTTGGCTTTGGCGGTACCAATGCAACACTAATCATCA
AAAAGTTTGACGCTTAAACT

Downstream 100 bases:

>100_bases
GCTTTATATTCGAAAACAGCTTAAAGCGGCGCAAAAGAGCCTGCTCACATCATGTGAGCAGGCTCTTTTTATTACTTATG
AAATATTGTTTTAGTACTAT

Product: anthranilate synthase component I/chorismate-binding protein

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MVVIDTHTTVQTDSALPPASKTSWRFGDLSAAELMPHLQRHLLEQNSKANWQLVWLNNDGRPVIGLLPKTSWCVYPVTNN
TLHATKQGNLCKIEKTRRGHVHLYSNSSDSAATSYMSYSDWQEELITYSRAHEIDGIHGNGSFSTKDVDQQPSYQHGLIG
FISYDISAHELSPTVNIEMAAQPCALLGHYDIYLTADSDSQSSWQLKVNNDNNPDSSSVQQDTNALIRVLTSYLNSLDNQ
LSNENVTKKYSCKTPPLLLEAQWSKRHYQQAFHQTQNYLQQGDCYQINLTQAWSGYLSTYEDNSVTSLIDYLPALHANTQ
APFAGYIAIDSYNHEGKVNTSNHQFELLSCSPELFFTFSKDIETDKHHIRTKPIKGTMPRGLTTEQDNDYKQQLINSEKD
RAENVMIVDLLRNDLGKYAKIGSVKVPQLFAIESFSNVHHMVSTITAELKTDTHPLSVLFGSLPAGSITGTPKKRAVEII
AELEGAPRSAYCGTMGYMNFDGSGQWNVLIRTLQATSTADNSKQVSLWAGGGITVASDCDAEYQECLDKVGNLLSVLANT
ANH

Sequences:

>Translated_563_residues
MVVIDTHTTVQTDSALPPASKTSWRFGDLSAAELMPHLQRHLLEQNSKANWQLVWLNNDGRPVIGLLPKTSWCVYPVTNN
TLHATKQGNLCKIEKTRRGHVHLYSNSSDSAATSYMSYSDWQEELITYSRAHEIDGIHGNGSFSTKDVDQQPSYQHGLIG
FISYDISAHELSPTVNIEMAAQPCALLGHYDIYLTADSDSQSSWQLKVNNDNNPDSSSVQQDTNALIRVLTSYLNSLDNQ
LSNENVTKKYSCKTPPLLLEAQWSKRHYQQAFHQTQNYLQQGDCYQINLTQAWSGYLSTYEDNSVTSLIDYLPALHANTQ
APFAGYIAIDSYNHEGKVNTSNHQFELLSCSPELFFTFSKDIETDKHHIRTKPIKGTMPRGLTTEQDNDYKQQLINSEKD
RAENVMIVDLLRNDLGKYAKIGSVKVPQLFAIESFSNVHHMVSTITAELKTDTHPLSVLFGSLPAGSITGTPKKRAVEII
AELEGAPRSAYCGTMGYMNFDGSGQWNVLIRTLQATSTADNSKQVSLWAGGGITVASDCDAEYQECLDKVGNLLSVLANT
ANH
>Mature_563_residues
MVVIDTHTTVQTDSALPPASKTSWRFGDLSAAELMPHLQRHLLEQNSKANWQLVWLNNDGRPVIGLLPKTSWCVYPVTNN
TLHATKQGNLCKIEKTRRGHVHLYSNSSDSAATSYMSYSDWQEELITYSRAHEIDGIHGNGSFSTKDVDQQPSYQHGLIG
FISYDISAHELSPTVNIEMAAQPCALLGHYDIYLTADSDSQSSWQLKVNNDNNPDSSSVQQDTNALIRVLTSYLNSLDNQ
LSNENVTKKYSCKTPPLLLEAQWSKRHYQQAFHQTQNYLQQGDCYQINLTQAWSGYLSTYEDNSVTSLIDYLPALHANTQ
APFAGYIAIDSYNHEGKVNTSNHQFELLSCSPELFFTFSKDIETDKHHIRTKPIKGTMPRGLTTEQDNDYKQQLINSEKD
RAENVMIVDLLRNDLGKYAKIGSVKVPQLFAIESFSNVHHMVSTITAELKTDTHPLSVLFGSLPAGSITGTPKKRAVEII
AELEGAPRSAYCGTMGYMNFDGSGQWNVLIRTLQATSTADNSKQVSLWAGGGITVASDCDAEYQECLDKVGNLLSVLANT
ANH

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=410, Percent_Identity=37.0731707317073, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1787518, Length=341, Percent_Identity=26.6862170087977, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1786809, Length=212, Percent_Identity=25.9433962264151, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=437, Percent_Identity=27.9176201372998, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6324361, Length=309, Percent_Identity=28.8025889967638, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 62640; Mature: 62640

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIDTHTTVQTDSALPPASKTSWRFGDLSAAELMPHLQRHLLEQNSKANWQLVWLNNDG
CEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
RPVIGLLPKTSWCVYPVTNNTLHATKQGNLCKIEKTRRGHVHLYSNSSDSAATSYMSYSD
CEEEEECCCCCEEEEECCCCEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHH
WQEELITYSRAHEIDGIHGNGSFSTKDVDQQPSYQHGLIGFISYDISAHELSPTVNIEMA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHCCCEEEEEEC
AQPCALLGHYDIYLTADSDSQSSWQLKVNNDNNPDSSSVQQDTNALIRVLTSYLNSLDNQ
CCCEEEEECEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSNENVTKKYSCKTPPLLLEAQWSKRHYQQAFHQTQNYLQQGDCYQINLTQAWSGYLSTY
HCCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHCC
EDNSVTSLIDYLPALHANTQAPFAGYIAIDSYNHEGKVNTSNHQFELLSCSPELFFTFSK
CCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEECCCCEEEEEECCCEEEEEECC
DIETDKHHIRTKPIKGTMPRGLTTEQDNDYKQQLINSEKDRAENVMIVDLLRNDLGKYAK
CCCCCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHCCEEEHHHHHHHHHHHHC
IGSVKVPQLFAIESFSNVHHMVSTITAELKTDTHPLSVLFGSLPAGSITGTPKKRAVEII
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHH
AELEGAPRSAYCGTMGYMNFDGSGQWNVLIRTLQATSTADNSKQVSLWAGGGITVASDCD
HHHCCCCCCCCCCCCCEEECCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCEEEECCCC
AEYQECLDKVGNLLSVLANTANH
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVVIDTHTTVQTDSALPPASKTSWRFGDLSAAELMPHLQRHLLEQNSKANWQLVWLNNDG
CEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
RPVIGLLPKTSWCVYPVTNNTLHATKQGNLCKIEKTRRGHVHLYSNSSDSAATSYMSYSD
CEEEEECCCCCEEEEECCCCEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHH
WQEELITYSRAHEIDGIHGNGSFSTKDVDQQPSYQHGLIGFISYDISAHELSPTVNIEMA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHCCCEEEEEEC
AQPCALLGHYDIYLTADSDSQSSWQLKVNNDNNPDSSSVQQDTNALIRVLTSYLNSLDNQ
CCCEEEEECEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSNENVTKKYSCKTPPLLLEAQWSKRHYQQAFHQTQNYLQQGDCYQINLTQAWSGYLSTY
HCCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHCC
EDNSVTSLIDYLPALHANTQAPFAGYIAIDSYNHEGKVNTSNHQFELLSCSPELFFTFSK
CCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEECCCCEEEEEECCCEEEEEECC
DIETDKHHIRTKPIKGTMPRGLTTEQDNDYKQQLINSEKDRAENVMIVDLLRNDLGKYAK
CCCCCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHCCEEEHHHHHHHHHHHHC
IGSVKVPQLFAIESFSNVHHMVSTITAELKTDTHPLSVLFGSLPAGSITGTPKKRAVEII
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHH
AELEGAPRSAYCGTMGYMNFDGSGQWNVLIRTLQATSTADNSKQVSLWAGGGITVASDCD
HHHCCCCCCCCCCCCCEEECCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCEEEECCCC
AEYQECLDKVGNLLSVLANTANH
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]