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The map label for this gene is ccmE [H]

Identifier: 93006933

GI number: 93006933

Start: 2583930

End: 2584430

Strand: Reverse

Name: ccmE [H]

Synonym: Pcryo_2109

Alternate gene names: 93006933

Gene position: 2584430-2583930 (Counterclockwise)

Preceding gene: 93006934

Following gene: 93006925

Centisome position: 84.46

GC content: 46.91

Gene sequence:

>501_bases
ATGAACGCAGTTCGTCGTAAAAAACTGATGTGGGTTATGTTTACGCTTGCAGGGGCAGCCATAGCCGTGGTATTGGTGAT
TTATGCCATTGGGCAACAGACCGACTACTACTTTGACGCGACTGCCATTGCGCAAGGTGAAGCGCCACAAGACAAACGTA
TTCGTGCTGGTGGTATGGTGGTTGCTGGTAGTGTACAGCGTGCGCCAAACGACCCATTGAGCGTTGAATTTGCCATCACA
GACTTTCAATCGACCGTCCCCGTGACTTATCAAGGTATTTTGCCAGATTTGTTCGCTGAGAACTCAGGTGTTGTCGCGAC
GGGTAAAATGCAAGGTGATACCTTTGTCGCAGGTGAAGTGCTGGCAAAACATGATGAGAACTATATGCCGCCAGAAGTTG
CTAAATCGATGAAAGAAAATAATCGCATTGGTGCAGTTCCTTCTTCTGAGCAATACAATCCTGCTGAAAAAGTTCATGAG
ACCAAGACTTTACAGCAGTAA

Upstream 100 bases:

>100_bases
AGACATTTTTAGGACGTTTTTCTAATGGTAGTTTCTTTAATATTTTCTGTTTTATAGATGGATAATGTCTAAAACAGCGA
CTCATCAATGAGGTAGTAGT

Downstream 100 bases:

>100_bases
TTGCGCTGGCAACAATAAACGATAATTATCGTAAAAAGCATTAAACATAAAAAAATCCAGTGACCTTTATCACTGGATTT
TTTTTGGCAAACCTCATACT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNAVRRKKLMWVMFTLAGAAIAVVLVIYAIGQQTDYYFDATAIAQGEAPQDKRIRAGGMVVAGSVQRAPNDPLSVEFAIT
DFQSTVPVTYQGILPDLFAENSGVVATGKMQGDTFVAGEVLAKHDENYMPPEVAKSMKENNRIGAVPSSEQYNPAEKVHE
TKTLQQ

Sequences:

>Translated_166_residues
MNAVRRKKLMWVMFTLAGAAIAVVLVIYAIGQQTDYYFDATAIAQGEAPQDKRIRAGGMVVAGSVQRAPNDPLSVEFAIT
DFQSTVPVTYQGILPDLFAENSGVVATGKMQGDTFVAGEVLAKHDENYMPPEVAKSMKENNRIGAVPSSEQYNPAEKVHE
TKTLQQ
>Mature_166_residues
MNAVRRKKLMWVMFTLAGAAIAVVLVIYAIGQQTDYYFDATAIAQGEAPQDKRIRAGGMVVAGSVQRAPNDPLSVEFAIT
DFQSTVPVTYQGILPDLFAENSGVVATGKMQGDTFVAGEVLAKHDENYMPPEVAKSMKENNRIGAVPSSEQYNPAEKVHE
TKTLQQ

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=160, Percent_Identity=45.625, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 18037; Mature: 18037

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVRRKKLMWVMFTLAGAAIAVVLVIYAIGQQTDYYFDATAIAQGEAPQDKRIRAGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEECCCEE
VAGSVQRAPNDPLSVEFAITDFQSTVPVTYQGILPDLFAENSGVVATGKMQGDTFVAGEV
EECCCCCCCCCCCEEEEEEECCCCCCCEEEECCCHHHHCCCCCEEEECCCCCCEEEHHHH
LAKHDENYMPPEVAKSMKENNRIGAVPSSEQYNPAEKVHETKTLQQ
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNAVRRKKLMWVMFTLAGAAIAVVLVIYAIGQQTDYYFDATAIAQGEAPQDKRIRAGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEECCCEE
VAGSVQRAPNDPLSVEFAITDFQSTVPVTYQGILPDLFAENSGVVATGKMQGDTFVAGEV
EECCCCCCCCCCCEEEEEEECCCCCCCEEEECCCHHHHCCCCCEEEECCCCCCEEEHHHH
LAKHDENYMPPEVAKSMKENNRIGAVPSSEQYNPAEKVHETKTLQQ
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA