Click here to switch to the map view.

The map label for this gene is hemR [H]

Identifier: 93006736

GI number: 93006736

Start: 2360796

End: 2362889

Strand: Reverse

Name: hemR [H]

Synonym: Pcryo_1912

Alternate gene names: 93006736

Gene position: 2362889-2360796 (Counterclockwise)

Preceding gene: 93006738

Following gene: 93006735

Centisome position: 77.22

GC content: 45.75

Gene sequence:

>2094_bases
ATGCGCGAAGTAAAATTATCAAGATTTTCTAGTCGATTGACCGTATTGTCTATGGGCGTAGCAGCAGTATTGGGGGCACA
AGCGGCGAGTGCTACGACCTCAGCAGATATGCCGAGCACTACCTTACAGACCATCACAGTGACGGCAAACAGCTCAGTAC
GTGAAAGCGTGCAAGAGGGCGGTGTTGATGTTGAAGGCTATACCCCAGCTGCGCAGGCAAGCCACTTAAGTGATTTTTTA
AATGTCGTACCCGGTGTTACGGTAGGCGGTACGTCAGCGGTCAATCAGCGTATACGCGTACGTGGACTCGATGATACCAA
TTTGAAAGTGACCATTGATGGCGCTCGCCAAGAAGGCACGCTGTTTTATCATATGGGCGATGTGACCATTGACCCTGATT
TGCTAAAACAAGCGGAAGTATCGGTCGGTAATAACTCAGTGACACTAGGTAACGATGCGCTAGGTGGCGCAGTTGCTTTT
AAAACTGTTGATGCCGCAGATCTACTAAAACCGGGACAAAAAATCGGTGCCAAACTGCACGCAGGTTATGCTAGTAATAA
TGATGAATTGCTCACCTCAGCGACTGTGTTTGCTGCCCCAACGGATAATATAGACTTACTGGCTTATTATGGTCAGCGTA
ATGCCAATGCTGGTGAAGATGGCGAAGGTCGTAAGATCCAAACGGAAGATAGCAAAGGCGAGAATATTTTATTAAAGGCG
GGCGCGTATATTGCCAATGACCATCACGTAGGGGCTAGCTTTAGCCGTACCGAAAACGAAGGCATGTTCCCATTACGCCC
AGATTTCCCAGCAAGCCCAGGCGTTGGCAGTTGGAATGAAATTCTACCGCAAAAGGTTAAGCGTGATACTTATGGGCTGG
ACTATAGCTACAATCCTGCCAGTAACTTGGTCAATGTCGATACCAATGTTTATCAAACCGAAACGCAGATTTCACGCGAT
ACGGACTATACGACAAAGCCAGGTTATAACTGGGAAGCGGGCGTAAAAACCACGGGCGCAAAAATTCAAAATACCAGTGT
TATTGATACCAATGTCGGCAGCCATAAACTAATCGCCGGTGTTGAGCACTATAAAAAAGAATCTGAGCTAGAGCGTGACT
TCGTTAAAAAGGGCACCGATGAAGCCAAGAATACCTCTATTTATCTAGAAGATCAGTGGAAAAATGGCAAATTAACCTTA
ACGCCGGGCATACGCTACGACCGTTATGAGTCGCCTGAATTTGTTGCTGGTGGCAAAACTTATGACAATGTCGTTGGTGC
GCTTGCAGCAAGCTATGAGATTGCACCGTTAACGCAAGTGTTTGCCAGTTATACGCAGTTATTTAACGGTCCTGATTTGA
GCCAAGCGATTTTTAACTCAGATGGCGACAAAACCTACGTCAATAAAGACTTAAAAGCAGAAGAAGGATCAAATGCTGAG
ATTGGTATCGTTAAAACATTGCGTGACCTAACGGTAGCGGGTGATGCGTTACAACTTAGCGGAAAATATTTTGAAACTGA
TATCGAAAACTTTATTGAATTTGTCCGTTCTGGTGGTACTCGCGTTGGCTTAGACTGTACCACTGGACAACTTGGTGGCG
CTTGCCAAGGCGCGGTCAATAAAGATGAAGATTATAAAATTAAGGGTGTTGAGCTCGCTGCTGACTATAAAATGGATAGT
TTTAGCATGGGTCTAAGCTATGCCCATGCACGTAGCAAAGGTGATAAAACGGGCTATAGCATCCCATCAGTAACGGGTGG
CAGTGCCGACTCTGGCGATAAATATATGGTGAACTTGGCCTACGTACCAACAGACACCACCGAGCTGGGCTGGCGCAGTA
CCTATGTGGCTGCCATCACGCCCAAAACTGAATCTGCCCAGCTTGAAAAGTCTAACTATGATGTGCATGATATTTTTATG
AGCTATATGCCAAAACAAGTCGATGGTTTAAAAGCGACTGTTGGGGTTTATAATATCTTTGATGAAACCTATGCCAGCCA
TGCGTCACGTTCGCTTACAGAACAAGCAGATGGTTTGCGCACCGACTTTGAACCCGGTCGCAATATCAAAGCATCTTTAA
CCTATCAGTTCTAA

Upstream 100 bases:

>100_bases
AGCATCAAGCTTTTTAGAAAGTAATTTTGGGCAAAAATTACTGATTATTGATTTCCTAAACGAGTTTTAAAATTCTTATA
CTAGATAAAGTGAGTATGTT

Downstream 100 bases:

>100_bases
ATTTATACTGATCATGCGTAAAAAATGAGTGTTAAAAAAGCCAGCTGCTTTGTATAAGAGCTGGCTTTTTTATGTCGAAA
CCTCTTTTTTAAACCATATG

Product: TonB-dependent heme/hemoglobin receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MREVKLSRFSSRLTVLSMGVAAVLGAQAASATTSADMPSTTLQTITVTANSSVRESVQEGGVDVEGYTPAAQASHLSDFL
NVVPGVTVGGTSAVNQRIRVRGLDDTNLKVTIDGARQEGTLFYHMGDVTIDPDLLKQAEVSVGNNSVTLGNDALGGAVAF
KTVDAADLLKPGQKIGAKLHAGYASNNDELLTSATVFAAPTDNIDLLAYYGQRNANAGEDGEGRKIQTEDSKGENILLKA
GAYIANDHHVGASFSRTENEGMFPLRPDFPASPGVGSWNEILPQKVKRDTYGLDYSYNPASNLVNVDTNVYQTETQISRD
TDYTTKPGYNWEAGVKTTGAKIQNTSVIDTNVGSHKLIAGVEHYKKESELERDFVKKGTDEAKNTSIYLEDQWKNGKLTL
TPGIRYDRYESPEFVAGGKTYDNVVGALAASYEIAPLTQVFASYTQLFNGPDLSQAIFNSDGDKTYVNKDLKAEEGSNAE
IGIVKTLRDLTVAGDALQLSGKYFETDIENFIEFVRSGGTRVGLDCTTGQLGGACQGAVNKDEDYKIKGVELAADYKMDS
FSMGLSYAHARSKGDKTGYSIPSVTGGSADSGDKYMVNLAYVPTDTTELGWRSTYVAAITPKTESAQLEKSNYDVHDIFM
SYMPKQVDGLKATVGVYNIFDETYASHASRSLTEQADGLRTDFEPGRNIKASLTYQF

Sequences:

>Translated_697_residues
MREVKLSRFSSRLTVLSMGVAAVLGAQAASATTSADMPSTTLQTITVTANSSVRESVQEGGVDVEGYTPAAQASHLSDFL
NVVPGVTVGGTSAVNQRIRVRGLDDTNLKVTIDGARQEGTLFYHMGDVTIDPDLLKQAEVSVGNNSVTLGNDALGGAVAF
KTVDAADLLKPGQKIGAKLHAGYASNNDELLTSATVFAAPTDNIDLLAYYGQRNANAGEDGEGRKIQTEDSKGENILLKA
GAYIANDHHVGASFSRTENEGMFPLRPDFPASPGVGSWNEILPQKVKRDTYGLDYSYNPASNLVNVDTNVYQTETQISRD
TDYTTKPGYNWEAGVKTTGAKIQNTSVIDTNVGSHKLIAGVEHYKKESELERDFVKKGTDEAKNTSIYLEDQWKNGKLTL
TPGIRYDRYESPEFVAGGKTYDNVVGALAASYEIAPLTQVFASYTQLFNGPDLSQAIFNSDGDKTYVNKDLKAEEGSNAE
IGIVKTLRDLTVAGDALQLSGKYFETDIENFIEFVRSGGTRVGLDCTTGQLGGACQGAVNKDEDYKIKGVELAADYKMDS
FSMGLSYAHARSKGDKTGYSIPSVTGGSADSGDKYMVNLAYVPTDTTELGWRSTYVAAITPKTESAQLEKSNYDVHDIFM
SYMPKQVDGLKATVGVYNIFDETYASHASRSLTEQADGLRTDFEPGRNIKASLTYQF
>Mature_697_residues
MREVKLSRFSSRLTVLSMGVAAVLGAQAASATTSADMPSTTLQTITVTANSSVRESVQEGGVDVEGYTPAAQASHLSDFL
NVVPGVTVGGTSAVNQRIRVRGLDDTNLKVTIDGARQEGTLFYHMGDVTIDPDLLKQAEVSVGNNSVTLGNDALGGAVAF
KTVDAADLLKPGQKIGAKLHAGYASNNDELLTSATVFAAPTDNIDLLAYYGQRNANAGEDGEGRKIQTEDSKGENILLKA
GAYIANDHHVGASFSRTENEGMFPLRPDFPASPGVGSWNEILPQKVKRDTYGLDYSYNPASNLVNVDTNVYQTETQISRD
TDYTTKPGYNWEAGVKTTGAKIQNTSVIDTNVGSHKLIAGVEHYKKESELERDFVKKGTDEAKNTSIYLEDQWKNGKLTL
TPGIRYDRYESPEFVAGGKTYDNVVGALAASYEIAPLTQVFASYTQLFNGPDLSQAIFNSDGDKTYVNKDLKAEEGSNAE
IGIVKTLRDLTVAGDALQLSGKYFETDIENFIEFVRSGGTRVGLDCTTGQLGGACQGAVNKDEDYKIKGVELAADYKMDS
FSMGLSYAHARSKGDKTGYSIPSVTGGSADSGDKYMVNLAYVPTDTTELGWRSTYVAAITPKTESAQLEKSNYDVHDIFM
SYMPKQVDGLKATVGVYNIFDETYASHASRSLTEQADGLRTDFEPGRNIKASLTYQF

Specific function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75130; Mature: 75130

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVKLSRFSSRLTVLSMGVAAVLGAQAASATTSADMPSTTLQTITVTANSSVRESVQEG
CCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHC
GVDVEGYTPAAQASHLSDFLNVVPGVTVGGTSAVNQRIRVRGLDDTNLKVTIDGARQEGT
CCEECCCCCHHHHHHHHHHHHHHCCCEECCHHHHCCEEEEEECCCCCEEEEEECCCCCCE
LFYHMGDVTIDPDLLKQAEVSVGNNSVTLGNDALGGAVAFKTVDAADLLKPGQKIGAKLH
EEEEECCEEECHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCHHHHHCCCHHHCCEEE
AGYASNNDELLTSATVFAAPTDNIDLLAYYGQRNANAGEDGEGRKIQTEDSKGENILLKA
ECCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEEEEEC
GAYIANDHHVGASFSRTENEGMFPLRPDFPASPGVGSWNEILPQKVKRDTYGLDYSYNPA
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
SNLVNVDTNVYQTETQISRDTDYTTKPGYNWEAGVKTTGAKIQNTSVIDTNVGSHKLIAG
CCEEECCCCEEECHHHHCCCCCCCCCCCCCCCCCCEECCCEEECCEEEECCCCCCHHHHH
VEHYKKESELERDFVKKGTDEAKNTSIYLEDQWKNGKLTLTPGIRYDRYESPEFVAGGKT
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCEEECCCH
YDNVVGALAASYEIAPLTQVFASYTQLFNGPDLSQAIFNSDGDKTYVNKDLKAEEGSNAE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCE
IGIVKTLRDLTVAGDALQLSGKYFETDIENFIEFVRSGGTRVGLDCTTGQLGGACQGAVN
EEHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
KDEDYKIKGVELAADYKMDSFSMGLSYAHARSKGDKTGYSIPSVTGGSADSGDKYMVNLA
CCCCEEEEEEEEEECCCCCHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
YVPTDTTELGWRSTYVAAITPKTESAQLEKSNYDVHDIFMSYMPKQVDGLKATVGVYNIF
EECCCCCCCCCCEEEEEEECCCCCCCHHHCCCCCHHHHHHHHCCCHHCCCEEEHHHHHHH
DETYASHASRSLTEQADGLRTDFEPGRNIKASLTYQF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MREVKLSRFSSRLTVLSMGVAAVLGAQAASATTSADMPSTTLQTITVTANSSVRESVQEG
CCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHC
GVDVEGYTPAAQASHLSDFLNVVPGVTVGGTSAVNQRIRVRGLDDTNLKVTIDGARQEGT
CCEECCCCCHHHHHHHHHHHHHHCCCEECCHHHHCCEEEEEECCCCCEEEEEECCCCCCE
LFYHMGDVTIDPDLLKQAEVSVGNNSVTLGNDALGGAVAFKTVDAADLLKPGQKIGAKLH
EEEEECCEEECHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCHHHHHCCCHHHCCEEE
AGYASNNDELLTSATVFAAPTDNIDLLAYYGQRNANAGEDGEGRKIQTEDSKGENILLKA
ECCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEEEEEC
GAYIANDHHVGASFSRTENEGMFPLRPDFPASPGVGSWNEILPQKVKRDTYGLDYSYNPA
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
SNLVNVDTNVYQTETQISRDTDYTTKPGYNWEAGVKTTGAKIQNTSVIDTNVGSHKLIAG
CCEEECCCCEEECHHHHCCCCCCCCCCCCCCCCCCEECCCEEECCEEEECCCCCCHHHHH
VEHYKKESELERDFVKKGTDEAKNTSIYLEDQWKNGKLTLTPGIRYDRYESPEFVAGGKT
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCEEECCCH
YDNVVGALAASYEIAPLTQVFASYTQLFNGPDLSQAIFNSDGDKTYVNKDLKAEEGSNAE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCE
IGIVKTLRDLTVAGDALQLSGKYFETDIENFIEFVRSGGTRVGLDCTTGQLGGACQGAVN
EEHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
KDEDYKIKGVELAADYKMDSFSMGLSYAHARSKGDKTGYSIPSVTGGSADSGDKYMVNLA
CCCCEEEEEEEEEECCCCCHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
YVPTDTTELGWRSTYVAAITPKTESAQLEKSNYDVHDIFMSYMPKQVDGLKATVGVYNIF
EECCCCCCCCCCEEEEEEECCCCCCCHHHCCCCCHHHHHHHHCCCHHCCCEEEHHHHHHH
DETYASHASRSLTEQADGLRTDFEPGRNIKASLTYQF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1425573 [H]