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The map label for this gene is yaeL [C]

Identifier: 93006533

GI number: 93006533

Start: 2115935

End: 2117308

Strand: Reverse

Name: yaeL [C]

Synonym: Pcryo_1709

Alternate gene names: 93006533

Gene position: 2117308-2115935 (Counterclockwise)

Preceding gene: 93006534

Following gene: 93006532

Centisome position: 69.2

GC content: 43.96

Gene sequence:

>1374_bases
ATGACGTTTCTATTAACACTCCTTGCGGCAATATTTGTCTTAGGTCCGCTTATTGCTTTGCATGAGTGGGGTCATTATAT
TGTAGCGCGTCTTTGCGGCGTTAGAGTGCTCACATATTCTATTGGTTTTGGTCCTAAGCTTTTTGGCTGGACCAGCAAAA
AAAGTGGCATTGATTATCGTATCTCGGCATTACCCCTTGGTGGATATGTCAAAATGCTTGATGAGCGTGAAGGTGAGGTG
GCAAAAGATGAGCAGCATTTAGCATTTAATCGTCAGCATCCGCTTAAGAAAATAGCTATTGTGGCTGCTGGTCCTATCAT
GAACTTCGTTATTGCCATTGCATTGTTCTGGGTGTTATTTATGACTCCCTCAGAGCAGCTTGCCACCAAGATTGGTCAAG
TATTGCCGGATACGCCTGCCGCGATAGCACAGTTGCCTGCCGGTGATAAAATCGTTGCGATTGACGGTCATGACGTACAG
ACGTGGGAAGGGATTAATTATCGCCTTGCTGGGCGCATGGGCGAGACAGCCAATATAAGCGTGACGTTGCAATCAGAAGC
CAATAATAATGCAACCAAAACTTATCAAGCACCTGTAAAAGAATTTATGCAAGGTGCCGCACAAGGTAAAGATGCCTTAT
CAAGCTTTGGTATGATACCGTGGCAACCAAATATTGCACCGATAGTCGGTGATGTAACGCCTGATGGCGCGGCAAGTCGT
CAAGGTCTCAAGGCTGGCGACCGCATCACTGCTATCAATGATGAAGCCATTAATGACTGGATTAGCGCCACTCGTATTAT
CCGTGACAATCCTGAGACTTTGCTTACATTTAGCGTGTTACGTAATGATAAGCCGATTGAATTACAGATTATGCCGCAAG
GTAAAAAAGACAATTTAGGTAACGATTATGGACAAATTGGTGCTATGGTGGCACAGTCTGAGATTGTCATTCCTGATGCG
TACAAAACTACGGTGGTCTATGGTCCAGCTGAGTCGTTAATCAAATCGTTTGAGAAAACTGAGCAATTGGCTGTTATGAC
TGTCAGCTCAATGGGCAAGATGCTATCAGGTATGATAGGTCTTGATAACTTATCAGGTCCGATTACCATCGCAAAAGTCG
CTAAGCAAAGTTTTGATATCAGTTGGCAAATGGTATTATCTACCGCAGCCTTAATCAGTTTGAGCCTTGCGGTTTTGAAT
TTGTTGCCCATTCCAGTATTAGATGGCGGTCATATTGTCTATTATCTGATTGAGCTGATACGTGGTAAGCCACTCTCTGA
AGGCGTGCAAATGGTAGGCTTAAATATTGGTTTACTCTTGCTGGCAGGTTTCATGGTGTTAGCAATTGGTAATGATATCA
GTCGGCTGTTTTGA

Upstream 100 bases:

>100_bases
GCGCGTCAGCATACTGAGAAGCTGGTGGCAAGATTGGTTTAGATGTATCAAGTGCTATCGCCTTTATAATGATGTTAAGA
GTACCTACTGAGAAAAGATC

Downstream 100 bases:

>100_bases
TGATATAGCATACTTCTTGCACGGTAAGATGCGATAGACTAATGGTTTTATGCTTATCCTGTATCTATTGTTAGGCTAAT
AAGCAATTTCTTTTATCGCC

Product: peptidase M50 membrane-associated zinc metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTFLLTLLAAIFVLGPLIALHEWGHYIVARLCGVRVLTYSIGFGPKLFGWTSKKSGIDYRISALPLGGYVKMLDEREGEV
AKDEQHLAFNRQHPLKKIAIVAAGPIMNFVIAIALFWVLFMTPSEQLATKIGQVLPDTPAAIAQLPAGDKIVAIDGHDVQ
TWEGINYRLAGRMGETANISVTLQSEANNNATKTYQAPVKEFMQGAAQGKDALSSFGMIPWQPNIAPIVGDVTPDGAASR
QGLKAGDRITAINDEAINDWISATRIIRDNPETLLTFSVLRNDKPIELQIMPQGKKDNLGNDYGQIGAMVAQSEIVIPDA
YKTTVVYGPAESLIKSFEKTEQLAVMTVSSMGKMLSGMIGLDNLSGPITIAKVAKQSFDISWQMVLSTAALISLSLAVLN
LLPIPVLDGGHIVYYLIELIRGKPLSEGVQMVGLNIGLLLLAGFMVLAIGNDISRLF

Sequences:

>Translated_457_residues
MTFLLTLLAAIFVLGPLIALHEWGHYIVARLCGVRVLTYSIGFGPKLFGWTSKKSGIDYRISALPLGGYVKMLDEREGEV
AKDEQHLAFNRQHPLKKIAIVAAGPIMNFVIAIALFWVLFMTPSEQLATKIGQVLPDTPAAIAQLPAGDKIVAIDGHDVQ
TWEGINYRLAGRMGETANISVTLQSEANNNATKTYQAPVKEFMQGAAQGKDALSSFGMIPWQPNIAPIVGDVTPDGAASR
QGLKAGDRITAINDEAINDWISATRIIRDNPETLLTFSVLRNDKPIELQIMPQGKKDNLGNDYGQIGAMVAQSEIVIPDA
YKTTVVYGPAESLIKSFEKTEQLAVMTVSSMGKMLSGMIGLDNLSGPITIAKVAKQSFDISWQMVLSTAALISLSLAVLN
LLPIPVLDGGHIVYYLIELIRGKPLSEGVQMVGLNIGLLLLAGFMVLAIGNDISRLF
>Mature_456_residues
TFLLTLLAAIFVLGPLIALHEWGHYIVARLCGVRVLTYSIGFGPKLFGWTSKKSGIDYRISALPLGGYVKMLDEREGEVA
KDEQHLAFNRQHPLKKIAIVAAGPIMNFVIAIALFWVLFMTPSEQLATKIGQVLPDTPAAIAQLPAGDKIVAIDGHDVQT
WEGINYRLAGRMGETANISVTLQSEANNNATKTYQAPVKEFMQGAAQGKDALSSFGMIPWQPNIAPIVGDVTPDGAASRQ
GLKAGDRITAINDEAINDWISATRIIRDNPETLLTFSVLRNDKPIELQIMPQGKKDNLGNDYGQIGAMVAQSEIVIPDAY
KTTVVYGPAESLIKSFEKTEQLAVMTVSSMGKMLSGMIGLDNLSGPITIAKVAKQSFDISWQMVLSTAALISLSLAVLNL
LPIPVLDGGHIVYYLIELIRGKPLSEGVQMVGLNIGLLLLAGFMVLAIGNDISRLF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=457, Percent_Identity=38.5120350109409, Blast_Score=306, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49383; Mature: 49252

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLLTLLAAIFVLGPLIALHEWGHYIVARLCGVRVLTYSIGFGPKLFGWTSKKSGIDYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEE
ISALPLGGYVKMLDEREGEVAKDEQHLAFNRQHPLKKIAIVAAGPIMNFVIAIALFWVLF
EEEECCCHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHEEEEECCHHHHHHHHHHHHHHHH
MTPSEQLATKIGQVLPDTPAAIAQLPAGDKIVAIDGHDVQTWEGINYRLAGRMGETANIS
CCCCHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEEE
VTLQSEANNNATKTYQAPVKEFMQGAAQGKDALSSFGMIPWQPNIAPIVGDVTPDGAASR
EEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEECCCCCCCCCCC
QGLKAGDRITAINDEAINDWISATRIIRDNPETLLTFSVLRNDKPIELQIMPQGKKDNLG
CCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEEEEEECCCCCCCCC
NDYGQIGAMVAQSEIVIPDAYKTTVVYGPAESLIKSFEKTEQLAVMTVSSMGKMLSGMIG
CCHHHHHHHHHCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDNLSGPITIAKVAKQSFDISWQMVLSTAALISLSLAVLNLLPIPVLDGGHIVYYLIELI
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHH
RGKPLSEGVQMVGLNIGLLLLAGFMVLAIGNDISRLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
TFLLTLLAAIFVLGPLIALHEWGHYIVARLCGVRVLTYSIGFGPKLFGWTSKKSGIDYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEE
ISALPLGGYVKMLDEREGEVAKDEQHLAFNRQHPLKKIAIVAAGPIMNFVIAIALFWVLF
EEEECCCHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHEEEEECCHHHHHHHHHHHHHHHH
MTPSEQLATKIGQVLPDTPAAIAQLPAGDKIVAIDGHDVQTWEGINYRLAGRMGETANIS
CCCCHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEEE
VTLQSEANNNATKTYQAPVKEFMQGAAQGKDALSSFGMIPWQPNIAPIVGDVTPDGAASR
EEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEECCCCCCCCCCC
QGLKAGDRITAINDEAINDWISATRIIRDNPETLLTFSVLRNDKPIELQIMPQGKKDNLG
CCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEEEEEECCCCCCCCC
NDYGQIGAMVAQSEIVIPDAYKTTVVYGPAESLIKSFEKTEQLAVMTVSSMGKMLSGMIG
CCHHHHHHHHHCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDNLSGPITIAKVAKQSFDISWQMVLSTAALISLSLAVLNLLPIPVLDGGHIVYYLIELI
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHH
RGKPLSEGVQMVGLNIGLLLLAGFMVLAIGNDISRLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]