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The map label for this gene is lpxA [H]

Identifier: 93006529

GI number: 93006529

Start: 2110505

End: 2111284

Strand: Reverse

Name: lpxA [H]

Synonym: Pcryo_1705

Alternate gene names: 93006529

Gene position: 2111284-2110505 (Counterclockwise)

Preceding gene: 93006530

Following gene: 93006528

Centisome position: 69.0

GC content: 44.23

Gene sequence:

>780_bases
ATGAGTCAGATCCATCCCACAGCACTCATCTCACCGTCTGCTACGATTGATAAAACCGCAACCATTGGCCCTTACTGTAT
TGTCGGTGATGAGGTTACTATTGGTGCACATACTGTATTGCATCGCCACGTGGTCGTCACTAGATTGACTCGTATCGGTG
AATACAATCAGTTTTATCAATTTTCAAGCATTGGCGAAGACCCGCAAGACCTCAAATACGCAGGTGAGCGTACTTGGCTT
GAGATTGGTGATCATAATACCATTCGAGAAGCCTGTAGCTTGCACCGTGGTACTGAGCAAGATGGTGGGTTGACAAAAAT
TGGCAACCATAACTTGCTCATGGTTAACACTCATGTGGCTCATGATTGCTTGATTGGCGACCATAATGTATTGGCTAATA
ATGTTGGCGTCGCAGGTCACGTTACCATTGGCAATCATATTATTGTCGGTGGCAATTCAGGCATTCATCAGTTTTGTACA
ATTGATGATTATAGTTTGGTTGGTGGTGCAACGTTGGTCTTAAAAGATGTAGCGGCGTTTACCATGGTTTCAGGTAATCC
TGCTAAGGCACATGGTCTTAATATTGAAGGTATGCGCCGTAAAGGCTGGTCTAAAGATAGCATCGACGTGCTGCGTCAAG
CTTATCGTGTGGTATTCAGATCTGGTTTAACGACAGTGCAAGCACTTGAAGTATTGAAACAAGATCTGCTGCCAAAAGAG
TCAAAAATCGAATTTTTAATCGATTCGCTACAGAAAAGTCGCCGCGGAGTCGTGCGCTAA

Upstream 100 bases:

>100_bases
TATTTTTTAACAAAGGCAGCTTTAGGCTAGTTAATTTCACTAAGCTGTCTGTATTTGTTTTACTAATTTAATTGCATTCG
ATGATACAAAGGCCTCTATT

Downstream 100 bases:

>100_bases
ATTCTGTTTTGATACATCAGTAGCTCATTTTAAATAGTTTTTACCACCGAAACTAAATGTTATAAATAGTAATCATAAAT
ATAAAAAGCCATAACTAATA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSQIHPTALISPSATIDKTATIGPYCIVGDEVTIGAHTVLHRHVVVTRLTRIGEYNQFYQFSSIGEDPQDLKYAGERTWL
EIGDHNTIREACSLHRGTEQDGGLTKIGNHNLLMVNTHVAHDCLIGDHNVLANNVGVAGHVTIGNHIIVGGNSGIHQFCT
IDDYSLVGGATLVLKDVAAFTMVSGNPAKAHGLNIEGMRRKGWSKDSIDVLRQAYRVVFRSGLTTVQALEVLKQDLLPKE
SKIEFLIDSLQKSRRGVVR

Sequences:

>Translated_259_residues
MSQIHPTALISPSATIDKTATIGPYCIVGDEVTIGAHTVLHRHVVVTRLTRIGEYNQFYQFSSIGEDPQDLKYAGERTWL
EIGDHNTIREACSLHRGTEQDGGLTKIGNHNLLMVNTHVAHDCLIGDHNVLANNVGVAGHVTIGNHIIVGGNSGIHQFCT
IDDYSLVGGATLVLKDVAAFTMVSGNPAKAHGLNIEGMRRKGWSKDSIDVLRQAYRVVFRSGLTTVQALEVLKQDLLPKE
SKIEFLIDSLQKSRRGVVR
>Mature_258_residues
SQIHPTALISPSATIDKTATIGPYCIVGDEVTIGAHTVLHRHVVVTRLTRIGEYNQFYQFSSIGEDPQDLKYAGERTWLE
IGDHNTIREACSLHRGTEQDGGLTKIGNHNLLMVNTHVAHDCLIGDHNVLANNVGVAGHVTIGNHIIVGGNSGIHQFCTI
DDYSLVGGATLVLKDVAAFTMVSGNPAKAHGLNIEGMRRKGWSKDSIDVLRQAYRVVFRSGLTTVQALEVLKQDLLPKES
KIEFLIDSLQKSRRGVVR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=256, Percent_Identity=47.265625, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI1786376, Length=215, Percent_Identity=28.3720930232558, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28293; Mature: 28161

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIHPTALISPSATIDKTATIGPYCIVGDEVTIGAHTVLHRHVVVTRLTRIGEYNQFYQ
CCCCCCCEEECCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHH
FSSIGEDPQDLKYAGERTWLEIGDHNTIREACSLHRGTEQDGGLTKIGNHNLLMVNTHVA
HHCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEECCCC
HDCLIGDHNVLANNVGVAGHVTIGNHIIVGGNSGIHQFCTIDDYSLVGGATLVLKDVAAF
CCEEECCCCEECCCCCEEEEEEECCEEEECCCCCCCEEEEECCCHHHCCHHHHHHHHHHH
TMVSGNPAKAHGLNIEGMRRKGWSKDSIDVLRQAYRVVFRSGLTTVQALEVLKQDLLPKE
EEECCCCCHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
SKIEFLIDSLQKSRRGVVR
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQIHPTALISPSATIDKTATIGPYCIVGDEVTIGAHTVLHRHVVVTRLTRIGEYNQFYQ
CCCCCCEEECCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHH
FSSIGEDPQDLKYAGERTWLEIGDHNTIREACSLHRGTEQDGGLTKIGNHNLLMVNTHVA
HHCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEECCCC
HDCLIGDHNVLANNVGVAGHVTIGNHIIVGGNSGIHQFCTIDDYSLVGGATLVLKDVAAF
CCEEECCCCEECCCCCEEEEEEECCEEEECCCCCCCEEEEECCCHHHCCHHHHHHHHHHH
TMVSGNPAKAHGLNIEGMRRKGWSKDSIDVLRQAYRVVFRSGLTTVQALEVLKQDLLPKE
EEECCCCCHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
SKIEFLIDSLQKSRRGVVR
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA