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The map label for this gene is yhdH [H]

Identifier: 93006528

GI number: 93006528

Start: 2108845

End: 2110197

Strand: Reverse

Name: yhdH [H]

Synonym: Pcryo_1704

Alternate gene names: 93006528

Gene position: 2110197-2108845 (Counterclockwise)

Preceding gene: 93006529

Following gene: 93006526

Centisome position: 68.96

GC content: 42.5

Gene sequence:

>1353_bases
ATGGCTAGTAATAAACAAGATCATGCGCAGTGGAGCTCAAGTTTTGGCTTCGTACTTGCAGCAGTAGGCTCGGCAGTCGG
CTTAGGAAATATTTGGAAATTCCCTTATATGGTAGGTGAAAGCGGTGGTTCAGCTTTTGTTATTGCCTATTTGTTCTGTA
TTGCTTTGGTTGGTTTTCCTGTATTGGTCGCTGAGTGGCTCATTGGTCGCCGTGGTCAAAAGAATCCTATTAATACCTTT
AAAGATGTTGCTGTTAGTGAAGGTAAGTCAAGTAGCTGGGGTATTGTCGGTGCAACTGGTATCTTAGGTGGTTTTTTAAT
TCTCTCTTTTTATAGTGTCATCGGTGGCTGGGCGCTGAACTATATCACTAAAGTTGGCACGGGCAGTTTTGCCGGTCAAA
ACAGTGACTCTGTCGCTGCAACCTTTGATGGAATGCTAGCATCAGCAGGTACGCTAACGATTTGGCATACGGTATTTATG
ATCATTACTGCACTTATCGTAGGTATTGGTGTGACACGCGGTATTGAAAACGCTGCTAAAATCATGATGCCATTACTGGG
TGTGATTTTATTTATCATTGTTGGTTATAACGTGATAAATGGTGGTTTTGGTGAAGCGGTTAATTACTTGTTTGCACCTG
ATTTGAGCAAGTTGACCGTTGATGTAATGCTAGCGGCATTGGGTCATGCTTTCTTTACCCTATCTATTGGTATGGGCATC
ATGGTGGCTTATGGTTCATACTTAGGTCGTGAAGTGAACTTACTAAAAACTGCTCGTACGGTTGTTATTTTAGATACAGT
TATTGCCTTAGCAGCTGGTTTGGCCATTTTCCCAATCATCTTTAGCAATGGTCTTGATCCTGCATCAGGTCCTGGTTTGA
TTTTTGTCAGTCTACCGATTGCTTTTGGTAGCATGGCTGGTGGTACGATTATTGGTACTTTGTTCTTCTTATTGATTACC
TTTGCTGCTGTGACATCGTCGATATCATTGCTAGAGCCAAGTGTCGAGTTCTTAGAAGAACGCACATCTATGAACCGTAC
GATGTCTACCATTGCTGCTAGTACCGTGATTTGGCTATTGGGTATCGCTGCGCTATTGTCGTTTAACCTATGGAGCGACT
TTACTATCATGGGCAACGGCATCTTTGATGCACTAGACAAACTTACCAGTAAGTTCTTATTACCGCTAACCGGTCTTGCA
GGCATTATCTTCTTTGCTTGGAGAATGGACCAACGTAGCATTCAGCAAGAGCTTAATTTATCAAACGGTACTTGGCAGAT
TTGGCAAATCGTTACTAAATTTGTAGCGCCAATCGCAGTTATTGTGGTATTTGTGGCTGCATTGGTAGGCTAA

Upstream 100 bases:

>100_bases
ACATTGATGCATAGAGTAAATAGTCAAATATTATGGACAGCTATTTATAATAATCAAGGATGATTATAAGCAATATTAAT
TGAAGCATGAGGAAGGAAAA

Downstream 100 bases:

>100_bases
TCATTTATTCTTGATATGTATCCTGTTGATAGTTAGCTTGTCAAAATTTAGTGAACAAAAAAGGCTTAAGGTTGATCTTA
AGCCTTTTTTTGTATTTTAT

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MASNKQDHAQWSSSFGFVLAAVGSAVGLGNIWKFPYMVGESGGSAFVIAYLFCIALVGFPVLVAEWLIGRRGQKNPINTF
KDVAVSEGKSSSWGIVGATGILGGFLILSFYSVIGGWALNYITKVGTGSFAGQNSDSVAATFDGMLASAGTLTIWHTVFM
IITALIVGIGVTRGIENAAKIMMPLLGVILFIIVGYNVINGGFGEAVNYLFAPDLSKLTVDVMLAALGHAFFTLSIGMGI
MVAYGSYLGREVNLLKTARTVVILDTVIALAAGLAIFPIIFSNGLDPASGPGLIFVSLPIAFGSMAGGTIIGTLFFLLIT
FAAVTSSISLLEPSVEFLEERTSMNRTMSTIAASTVIWLLGIAALLSFNLWSDFTIMGNGIFDALDKLTSKFLLPLTGLA
GIIFFAWRMDQRSIQQELNLSNGTWQIWQIVTKFVAPIAVIVVFVAALVG

Sequences:

>Translated_450_residues
MASNKQDHAQWSSSFGFVLAAVGSAVGLGNIWKFPYMVGESGGSAFVIAYLFCIALVGFPVLVAEWLIGRRGQKNPINTF
KDVAVSEGKSSSWGIVGATGILGGFLILSFYSVIGGWALNYITKVGTGSFAGQNSDSVAATFDGMLASAGTLTIWHTVFM
IITALIVGIGVTRGIENAAKIMMPLLGVILFIIVGYNVINGGFGEAVNYLFAPDLSKLTVDVMLAALGHAFFTLSIGMGI
MVAYGSYLGREVNLLKTARTVVILDTVIALAAGLAIFPIIFSNGLDPASGPGLIFVSLPIAFGSMAGGTIIGTLFFLLIT
FAAVTSSISLLEPSVEFLEERTSMNRTMSTIAASTVIWLLGIAALLSFNLWSDFTIMGNGIFDALDKLTSKFLLPLTGLA
GIIFFAWRMDQRSIQQELNLSNGTWQIWQIVTKFVAPIAVIVVFVAALVG
>Mature_449_residues
ASNKQDHAQWSSSFGFVLAAVGSAVGLGNIWKFPYMVGESGGSAFVIAYLFCIALVGFPVLVAEWLIGRRGQKNPINTFK
DVAVSEGKSSSWGIVGATGILGGFLILSFYSVIGGWALNYITKVGTGSFAGQNSDSVAATFDGMLASAGTLTIWHTVFMI
ITALIVGIGVTRGIENAAKIMMPLLGVILFIIVGYNVINGGFGEAVNYLFAPDLSKLTVDVMLAALGHAFFTLSIGMGIM
VAYGSYLGREVNLLKTARTVVILDTVIALAAGLAIFPIIFSNGLDPASGPGLIFVSLPIAFGSMAGGTIIGTLFFLLITF
AAVTSSISLLEPSVEFLEERTSMNRTMSTIAASTVIWLLGIAALLSFNLWSDFTIMGNGIFDALDKLTSKFLLPLTGLAG
IIFFAWRMDQRSIQQELNLSNGTWQIWQIVTKFVAPIAVIVVFVAALVG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=499, Percent_Identity=23.6472945891784, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI58219014, Length=308, Percent_Identity=26.9480519480519, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI7657587, Length=419, Percent_Identity=25.0596658711217, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI289191377, Length=509, Percent_Identity=24.1650294695481, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI289191351, Length=509, Percent_Identity=24.1650294695481, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4557046, Length=509, Percent_Identity=24.1650294695481, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI194018524, Length=304, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI33354281, Length=307, Percent_Identity=25.0814332247557, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI21361581, Length=424, Percent_Identity=23.1132075471698, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI171184408, Length=412, Percent_Identity=24.2718446601942, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI171184406, Length=412, Percent_Identity=24.2718446601942, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI171184404, Length=412, Percent_Identity=24.2718446601942, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI11181770, Length=304, Percent_Identity=24.6710526315789, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4507041, Length=502, Percent_Identity=21.5139442231076, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4507043, Length=378, Percent_Identity=21.6931216931217, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI51468073, Length=303, Percent_Identity=22.4422442244224, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI197276623, Length=354, Percent_Identity=22.8813559322034, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI54607094, Length=354, Percent_Identity=22.8813559322034, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI134304856, Length=341, Percent_Identity=23.7536656891496, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI5032097, Length=351, Percent_Identity=24.5014245014245, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI92859670, Length=120, Percent_Identity=34.1666666666667, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21361693, Length=120, Percent_Identity=32.5, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI6005715, Length=135, Percent_Identity=30.3703703703704, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI12408638, Length=298, Percent_Identity=23.1543624161074, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI218563756, Length=351, Percent_Identity=23.9316239316239, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146584, Length=514, Percent_Identity=23.3463035019455, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17554804, Length=480, Percent_Identity=26.6666666666667, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17535731, Length=384, Percent_Identity=27.0833333333333, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17555248, Length=155, Percent_Identity=31.6129032258064, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI133952791, Length=141, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17136952, Length=379, Percent_Identity=24.2744063324538, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639514, Length=508, Percent_Identity=22.8346456692913, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI221329674, Length=508, Percent_Identity=22.8346456692913, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24661428, Length=500, Percent_Identity=22.8, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI281364394, Length=376, Percent_Identity=24.2021276595745, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574704, Length=376, Percent_Identity=24.2021276595745, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136950, Length=376, Percent_Identity=24.2021276595745, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574702, Length=376, Percent_Identity=24.2021276595745, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24652942, Length=500, Percent_Identity=24, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45551088, Length=500, Percent_Identity=24, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45550877, Length=391, Percent_Identity=24.5524296675192, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24654186, Length=534, Percent_Identity=21.7228464419476, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI45551183, Length=391, Percent_Identity=24.0409207161125, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655079, Length=306, Percent_Identity=25.1633986928105, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639516, Length=528, Percent_Identity=21.969696969697, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19921936, Length=375, Percent_Identity=27.7333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281365034, Length=407, Percent_Identity=24.5700245700246, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24762620, Length=492, Percent_Identity=21.3414634146341, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921352, Length=397, Percent_Identity=23.6775818639798, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24584353, Length=397, Percent_Identity=23.6775818639798, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24582567, Length=476, Percent_Identity=23.5294117647059, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363702, Length=364, Percent_Identity=25, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281363700, Length=334, Percent_Identity=25.748502994012, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639853, Length=510, Percent_Identity=21.1764705882353, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281364136, Length=401, Percent_Identity=22.9426433915212, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47643; Mature: 47511

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNKQDHAQWSSSFGFVLAAVGSAVGLGNIWKFPYMVGESGGSAFVIAYLFCIALVGFP
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCHHHHHHHHHHHHHHHH
VLVAEWLIGRRGQKNPINTFKDVAVSEGKSSSWGIVGATGILGGFLILSFYSVIGGWALN
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
YITKVGTGSFAGQNSDSVAATFDGMLASAGTLTIWHTVFMIITALIVGIGVTRGIENAAK
HHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
IMMPLLGVILFIIVGYNVINGGFGEAVNYLFAPDLSKLTVDVMLAALGHAFFTLSIGMGI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MVAYGSYLGREVNLLKTARTVVILDTVIALAAGLAIFPIIFSNGLDPASGPGLIFVSLPI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECH
AFGSMAGGTIIGTLFFLLITFAAVTSSISLLEPSVEFLEERTSMNRTMSTIAASTVIWLL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAALLSFNLWSDFTIMGNGIFDALDKLTSKFLLPLTGLAGIIFFAWRMDQRSIQQELNL
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
SNGTWQIWQIVTKFVAPIAVIVVFVAALVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASNKQDHAQWSSSFGFVLAAVGSAVGLGNIWKFPYMVGESGGSAFVIAYLFCIALVGFP
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCHHHHHHHHHHHHHHHH
VLVAEWLIGRRGQKNPINTFKDVAVSEGKSSSWGIVGATGILGGFLILSFYSVIGGWALN
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
YITKVGTGSFAGQNSDSVAATFDGMLASAGTLTIWHTVFMIITALIVGIGVTRGIENAAK
HHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
IMMPLLGVILFIIVGYNVINGGFGEAVNYLFAPDLSKLTVDVMLAALGHAFFTLSIGMGI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MVAYGSYLGREVNLLKTARTVVILDTVIALAAGLAIFPIIFSNGLDPASGPGLIFVSLPI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECH
AFGSMAGGTIIGTLFFLLITFAAVTSSISLLEPSVEFLEERTSMNRTMSTIAASTVIWLL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAALLSFNLWSDFTIMGNGIFDALDKLTSKFLLPLTGLAGIIFFAWRMDQRSIQQELNL
HHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
SNGTWQIWQIVTKFVAPIAVIVVFVAALVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]