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The map label for this gene is lpsI [H]

Identifier: 93006418

GI number: 93006418

Start: 1952267

End: 1952980

Strand: Reverse

Name: lpsI [H]

Synonym: Pcryo_1594

Alternate gene names: 93006418

Gene position: 1952980-1952267 (Counterclockwise)

Preceding gene: 93006421

Following gene: 93006417

Centisome position: 63.83

GC content: 45.52

Gene sequence:

>714_bases
ATGAGTCAATCAAAGGTGTATAACAGCGCAGAAGCGGCGTTGAGTGGTGTTGTGCGTAACGGACAAACGCTGGCGATCGG
TGGTTTTGGTCTATGCGGTATTCCTGAAGCGTTAATCGAAGCATTGCGGGATAGTGGTGTTGAAGATTTGACGTGCATCA
GTAATAACGCTGGTGTCGATGACTTTGGCTTGGGATTGTTATTACAGACGCGCCAAATTAAAAAAATGATCTCATCTTAT
GTGGGTGAAAATAAAGAGTTTGAGCGCCAGTACTTGGCAGGCGAGTTGGAAGTTGAGCTGACCCCGCAAGGCACCTTAGC
AGAAAAACTACGTTCAGGTGGTGCAGGTATTCCGGCATTTTATACCGCAACCGGCGTTGGTACCTTAGTTGCTGAAGGCA
AAGAAACCCGCGAATTTGACGGTCGTACTTATGTGCTTGAGCATTCATTACGCGCTGATGTGTCTCTAATCAAAGCGCAG
AAAGCGGATAAAGCAGGTAACTTAATCTTTAATAAAACGGCGCGTAATTTTAATCCAGACTGTGCGATGGCGGGCAAGAT
TACTATTGTTGAAGTTGAAGAGATCGTAGAAACAGGCACCTTAAATCCTGATGAGATTCATCTGCCGGGTATTTTTGTGC
AGCGTATCGTATTGAATAGCAGCCCTGAAAAGCGTATCGAAAAGACAACAACTAAAGTGGTCGAAGGCGCTTAG

Upstream 100 bases:

>100_bases
TAAATATAAAACTGATTGGTAGTCTAGTGTTTGCTTAAATAAGCAAAACCTATAATGAATCAATGTAAATAATAAAAATG
AGACGTGCAAGGAGATAAGC

Downstream 100 bases:

>100_bases
TCATTGCGATTACAGCATAATTAATAAATTATTAAATTTATAGTAATAGAATATCGTAAAAATTAAGGAAGCTATCATGG
CATGGACAAGAGAGCAGATG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSQSKVYNSAEAALSGVVRNGQTLAIGGFGLCGIPEALIEALRDSGVEDLTCISNNAGVDDFGLGLLLQTRQIKKMISSY
VGENKEFERQYLAGELEVELTPQGTLAEKLRSGGAGIPAFYTATGVGTLVAEGKETREFDGRTYVLEHSLRADVSLIKAQ
KADKAGNLIFNKTARNFNPDCAMAGKITIVEVEEIVETGTLNPDEIHLPGIFVQRIVLNSSPEKRIEKTTTKVVEGA

Sequences:

>Translated_237_residues
MSQSKVYNSAEAALSGVVRNGQTLAIGGFGLCGIPEALIEALRDSGVEDLTCISNNAGVDDFGLGLLLQTRQIKKMISSY
VGENKEFERQYLAGELEVELTPQGTLAEKLRSGGAGIPAFYTATGVGTLVAEGKETREFDGRTYVLEHSLRADVSLIKAQ
KADKAGNLIFNKTARNFNPDCAMAGKITIVEVEEIVETGTLNPDEIHLPGIFVQRIVLNSSPEKRIEKTTTKVVEGA
>Mature_236_residues
SQSKVYNSAEAALSGVVRNGQTLAIGGFGLCGIPEALIEALRDSGVEDLTCISNNAGVDDFGLGLLLQTRQIKKMISSYV
GENKEFERQYLAGELEVELTPQGTLAEKLRSGGAGIPAFYTATGVGTLVAEGKETREFDGRTYVLEHSLRADVSLIKAQK
ADKAGNLIFNKTARNFNPDCAMAGKITIVEVEEIVETGTLNPDEIHLPGIFVQRIVLNSSPEKRIEKTTTKVVEGA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=248, Percent_Identity=54.4354838709677, Blast_Score=277, Evalue=5e-75,
Organism=Homo sapiens, GI11545841, Length=231, Percent_Identity=54.1125541125541, Blast_Score=241, Evalue=5e-64,
Organism=Escherichia coli, GI1788551, Length=205, Percent_Identity=48.2926829268293, Blast_Score=207, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17531517, Length=246, Percent_Identity=54.8780487804878, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=54.5454545454545, Blast_Score=267, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=54.5454545454545, Blast_Score=267, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25434; Mature: 25303

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSKVYNSAEAALSGVVRNGQTLAIGGFGLCGIPEALIEALRDSGVEDLTCISNNAGVD
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
DFGLGLLLQTRQIKKMISSYVGENKEFERQYLAGELEVELTPQGTLAEKLRSGGAGIPAF
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCCE
YTATGVGTLVAEGKETREFDGRTYVLEHSLRADVSLIKAQKADKAGNLIFNKTARNFNPD
EHHHCHHHHHHCCCCHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
CAMAGKITIVEVEEIVETGTLNPDEIHLPGIFVQRIVLNSSPEKRIEKTTTKVVEGA
CEECCCEEEEEHHHHHHHCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQSKVYNSAEAALSGVVRNGQTLAIGGFGLCGIPEALIEALRDSGVEDLTCISNNAGVD
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
DFGLGLLLQTRQIKKMISSYVGENKEFERQYLAGELEVELTPQGTLAEKLRSGGAGIPAF
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCCE
YTATGVGTLVAEGKETREFDGRTYVLEHSLRADVSLIKAQKADKAGNLIFNKTARNFNPD
EHHHCHHHHHHCCCCHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
CAMAGKITIVEVEEIVETGTLNPDEIHLPGIFVQRIVLNSSPEKRIEKTTTKVVEGA
CEECCCEEEEEHHHHHHHCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]